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https://www.readbyqxmd.com/read/28435717/a-cinnamaldehyde-schiff-base-of-s-4-methyl-benz-yl-di-thio-carbazate-crystal-structure-hirshfeld-surface-analysis-and-computational-study
#1
Enis Nadia Md Yusof, Mohamed I M Tahir, Thahira B S A Ravoof, Sang Loon Tan, Edward R T Tiekink
The title di-thio-carbazate ester (I), C18H18N2S2 [systematic name: (E)-4-methyl-benzyl 2-[(E)-3-phenyl-allyl-idene]hydrazinecarbodi-thio-ate, comprises an almost planar central CN2S2 residue [r.m.s. deviation = 0.0131 Å]. The methyl-ene(tolyl-4) group forms a dihedral angle of 72.25 (4)° with the best plane through the remaining non-hydrogen atoms [r.m.s. deviation = 0.0586 Å] so the mol-ecule approximates mirror symmetry with the 4-tolyl group bis-ected by the plane. The configuration about both double bonds in the N-N=C-C=C chain is E; the chain has an all trans conformation...
April 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28435130/intramyometrial-injection-of-vasopressin-a-novel-method-for-hemostasis-at-laparoscopic-management-of-cornual-ectopic
#2
Ramesh Bettaiah, Shwetha Sudhakar Kamath
STUDY OBJECTIVE: Injection of vasopressin into the uterus , significantly reduces the vascularity of the cornual ectopic, thereby resulting in bloodless surgery. DESIGN: A step by step demonstration of the surgical procedure. Canadian task force classification III SETTING: while all ectopics are associated with risk of hemorrhage, cornual pregnancies are feared for catastrophic hemorrhage and uncontrollable bleeding. The maternal mortality rate can be as high as 2...
April 18, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28432398/ectes-abstracts-2017
#3
(no author information available yet)
No abstract text is available yet for this article.
April 21, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28431383/protocolized-hyperventilation-enhances-electroconvulsive-therapy
#4
Aida de Arriba-Arnau, Antonia Dalmau, Virginia Soria, Neus Salvat-Pujol, Carmina Ribes, Ana Sánchez-Allueva, José Manuel Menchón, Mikel Urretavizcaya
BACKGROUND: Hyperventilation is recommended in electroconvulsive therapy (ECT) to enhance seizures and to increase patients' safety. However, more evidence is needed regarding its effects and the optimum method of application. METHODS: This prospective study involving 21 subjects compared two procedures, protocolized hyperventilation (PHV) and hyperventilation as usual (HVau), applied to the same patient in two consecutive sessions. Transcutaneous partial pressure of carbon dioxide (TcPCO2) was measured throughout all sessions...
April 13, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28430980/the-relationship-between-symptom-relief-and-psychosocial-functional-improvement-during-acute-electroconvulsive-therapy-for-patients-with-major-depressive-disorder
#5
Ching-Hua Lin, Wei-Cheng Yang
Background: We aimed to compare the degree of symptom relief to psychosocial functional (abbreviated as "functional") improvement and explore the relationships between symptom relief and functional improvement during acute electroconvulsive therapy (ECT) for patients with major depressive disorder (MDD). Methods: MDD inpatients (N=130) requiring ECT were recruited. ECT was generally performed for a maximum of 12 treatments. Symptom severity, using the 17-item Hamilton Depression Rating Scale (HAMD-17), and psychosocial functioning (abbreviated as "functioning"), using the Modified Work and Social Adjustment Scale (MWSAS), were assessed before ECT, after every 3 ECT treatments, and after the final ECT...
April 18, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28430533/new-directions-in-the-rational-design-of-electrical-and-magnetic-seizure-therapies-individualized-low-amplitude-seizure-therapy-ilast-and-magnetic-seizure-therapy-mst
#6
Thomas Radman, Sarah H Lisanby
Electroconvulsive therapy remains a key treatment option for severe cases of depression, but undesirable side-effects continue to limit its use. Innovations in the design of novel seizure therapies seek to improve its risk benefit ratio through enhanced control of the focality of stimulation. The design of seizure therapies with increased spatial precision is motivated by avoiding stimulation of deep brain structures implicated in memory retention, including the hippocampus. The development of two innovations in seizure therapy-individualized low-amplitude seizure therapy (iLAST) and magnetic seizure therapy (MST), are detailed...
April 21, 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28426242/cellular-electron-cryotomography-toward-structural-biology-in-situ
#7
Catherine M Oikonomou, Grant J Jensen
Electron cryotomography (ECT) provides three-dimensional views of macromolecular complexes inside cells in a native frozen-hydrated state. Over the last two decades, ECT has revealed the ultrastructure of cells in unprecedented detail. It has also allowed us to visualize the structures of macromolecular machines in their native context inside intact cells. In many cases, such machines cannot be purified intact for in vitro study. In other cases, the function of a structure is lost outside the cell, so that the mechanism can be understood only by observation in situ...
April 19, 2017: Annual Review of Biochemistry
https://www.readbyqxmd.com/read/28424861/s-ketamine-compared-to-etomidate-during-electroconvulsive-therapy-in-major-depression
#8
Maxim Zavorotnyy, Ina Kluge, Kathrin Ahrens, Thomas Wohltmann, Benjamin Köhnlein, Patricia Dietsche, Udo Dannlowski, Tilo Kircher, Carsten Konrad
Objective of the study was to compare two commonly used anesthetic drugs, S-ketamine and etomidate, regarding their influence on seizure characteristics, safety aspects, and outcome of electroconvulsive therapy (ECT) in major depression. Treatment data of 60 patients who underwent a total number of 13 ECTs (median) because of the severe or treatment-resistant major depressive disorder (DSM-IV) were analyzed. Etomidate, mean dosage (SD) = 0.25 (0.04) mg/kg, was used for anesthesia in 29 participants; 31 patients received S-ketamine, mean dosage (SD) = 0...
April 19, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28422805/a-randomized-pilot-study-comparing-ketamine-and-methohexital-anesthesia-for-electroconvulsive-therapy-in-patients-with-depression
#9
Shona L Ray-Griffith, Lou Ann Eads, Xiaotong Han, Kimberly Golden, Zachary N Stowe
OBJECTIVE: This randomized controlled pilot study examines the differences in response to electroconvulsive therapy (ECT) as defined by an improvement of depressive symptoms between ketamine and methohexital as the primary anesthetic agent. Adverse effects and cognitive tolerability were also examined. METHODS: Subjects undergoing ECT for unipolar or bipolar depression were randomized to receive ketamine or methohexital as the anesthetic agent. Primary outcome measure includes the Hamilton rating scale for depression (17-item)...
April 18, 2017: Journal of ECT
https://www.readbyqxmd.com/read/28422271/a-systematic-review-of-left-unilateral-electroconvulsive-therapy
#10
REVIEW
C H Kellner, K G Farber, X R Chen, A Mehrotra, G D N Zipursky
OBJECTIVE: To systematically review the published clinical trials, case series, and case reports on left unilateral (LUL) electrode placement for clinical electroconvulsive therapy (ECT). METHOD: PubMed, Ovid Medline, and the Cochrane Library were searched for articles concerning LUL ECT. Number of patients, efficacy, and cognitive outcomes were extracted from the papers that met our inclusion criteria. RESULTS: A total of 52 articles were included in this review, consisting of 33 clinical trials, seven case series, and 12 case reports...
April 19, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28417028/general-anaesthesia-protocols-for-patients-undergoing-electroconvulsive-therapy-retrospective-analysis-of-504-sessions-over-a-five-year-period-at-a-tertiary-care-hospital-in-oman
#11
Aravind Narayanan, Chandar Lal, Hamed Al-Sinawi
OBJECTIVES: This study aimed to review general anaesthesia protocols for patients undergoing electroconvulsive therapy (ECT) at a tertiary care hospital in Oman, particularly with regards to clinical profile, potential drug interactions and patient outcomes. METHODS: This retrospective study took place at the Sultan Qaboos University Hospital (SQUH), Muscat, Oman. The electronic medical records of patients undergoing ECT at SQUH between January 2010 and December 2014 were reviewed for demographic characteristics and therapy details...
February 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/28413771/management-of-aromatase-inhibitor-associated-bone-loss-aibl-in-postmenopausal-women-with-hormone-sensitive-breast-cancer-joint-position-statement-of-the-iof-cabs-ects-ieg-esceo-ims-and-siog
#12
REVIEW
Peyman Hadji, Matti S Aapro, Jean-Jacques Body, Michael Gnant, Maria Luisa Brandi, Jean Yves Reginster, M Carola Zillikens, Claus-C Glüer, Tobie de Villiers, Rod Baber, G David Roodman, Cyrus Cooper, Bente Langdahl, Santiago Palacios, John Kanis, Nasser Al-Daghri, Xavier Nogues, Erik Fink Eriksen, Andreas Kurth, Rene Rizzoli, Robert E Coleman
BACKGROUND: Several guidelines have been reported for bone-directed treatment in women with early breast cancer (EBC) for averting fractures, particularly during aromatase inhibitor (AI) therapy. Recently, a number of studies on additional fracture related risk factors, new treatment options as well as real world studies demonstrating a much higher fracture rate than suggested by randomized clinical controlled trials (RCTs). Therefore, this updated algorithm was developed to better assess fracture risk and direct treatment as a position statement of several interdisciplinary cancer and bone societies involved in the management of AI-associated bone loss (AIBL)...
June 2017: Journal of Bone Oncology
https://www.readbyqxmd.com/read/28412557/electroconvulsive-therapy-changes-the-regional-resting-state-function-measured-by-regional-homogeneity-reho-and-amplitude-of-low-frequency-fluctuations-alff-in-elderly-major-depressive-disorder-patients-an-exploratory-study
#13
Xiao-Ming Kong, Shu-Xian Xu, Yan Sun, Ke-Yong Wang, Chen Wang, Ji Zhang, Jin-Xiang Xia, Li Zhang, Bo-Jian Tan, Xin-Hui Xie
Electroconvulsive therapy (ECT) is the most effective and rapid treatment for severe major depressive disorder (MDD) in elderly patients. The mechanism of ECT is unclear, and studies on ECT in elderly MDD patients by resting-state functional magnetic resonance imaging are rare. Thirteen elderly MDD patients were scanned before and after ECT using a 3.0T MRI scanner. Regional homogeneity (ReHo) and amplitude of low-frequency fluctuations (ALFF) were processed to compare resting-state function before and after treatment...
April 8, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28411470/incorporation-of-spheroidene-and-spheroidenone-into-light-harvesting-complexes-from-purple-sulfur-bacteria
#14
Aleksandr Ashikhmin, Zoya Makhneva, Maksim Bolshakov, Andrey Moskalenko
Spheroidene and spheroidenone from the non-sulfur bacterium Rhodobacter (Rba.) sphaeroides were incorporated into diphenylamine (DPA) LH1-RC and LH2 complexes from sulfur bacteria Allochromatium (Alc.) minutissimum and Ectothiorhodospira (Ect.) haloalkaliphila in which carotenoid (Car) biosynthesis was inhibited by ~95%. A series of biochemical characteristics of the modified LH2 complexes was studied (electrophoretic mobility, absorption and CD spectra, Car composition, Car-to-BChl energy transfer and thermal stability)...
March 30, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28406327/key-updates-in-the-clinical-application-of-electroconvulsive-therapy
#15
Richard D Weiner, Irving M Reti
ECT is the oldest and most effective therapy available for the treatment of severe major depression. It is highly effective in individuals with treatment resistance and when a rapid response is required. However, ECT is associated with memory impairment that is the most concerning side-effect of the treatment, substantially contributing to the controversy and stigmatization surrounding this highly effective treatment. There is overwhelming evidence for the efficacy and safety of an acute course of ECT for the treatment of a severe major depressive episode, as reflected by the recent FDA advisory panel recommendation to reclassify ECT devices from Class III to the lower risk category Class II...
April 13, 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28401340/seizure-threshold-increases-can-be-predicted-by-eeg-quality-in-right-unilateral-ultrabrief-ect
#16
Verònica Gálvez, Dusan Hadzi-Pavlovic, Susan Waite, Colleen K Loo
Increases in seizure threshold (ST) over a course of brief pulse ECT can be predicted by decreases in EEG quality, informing ECT dose adjustment to maintain adequate supra-threshold dosing. ST increases also occur over a course of right unilateral ultrabrief (RUL UB) ECT, but no data exist on the relationship between ST increases and EEG indices. This study (n = 35) investigated if increases in ST over RUL UB ECT treatments could be predicted by a decline in seizure quality. ST titration was performed at ECT session one and seven, with treatment dosing maintained stable (at 6-8 times ST) in intervening sessions...
April 11, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28397635/effects-of-electroconvulsive-therapy-on-amygdala-function-in-major-depression-a-longitudinal-functional-magnetic-resonance-imaging-study
#17
R Redlich, C Bürger, K Dohm, D Grotegerd, N Opel, D Zaremba, S Meinert, K Förster, J Repple, R Schnelle, C Wagenknecht, M Zavorotnyy, W Heindel, H Kugel, M Gerbaulet, J Alferink, V Arolt, P Zwanzger, U Dannlowski
BACKGROUND: Electroconvulsive therapy (ECT) is one of the most effective treatments for severe depression. However, little is known regarding brain functional processes mediating ECT effects. METHOD: In a non-randomized prospective study, functional magnetic resonance imaging data during the automatic processing of subliminally presented emotional faces were obtained twice, about 6 weeks apart, in patients with major depressive disorder (MDD) before and after treatment with ECT (ECT, n = 24)...
April 11, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28393840/antiviral-activity-of-chlorogenic-acid-against-influenza-a-h1n1-h3n2-virus-and-its-inhibition-of-neuraminidase
#18
Yue Ding, Zeyu Cao, Liang Cao, Gang Ding, Zhenzhong Wang, Wei Xiao
Lonicera japonica Thunb, rich in chlorogenic acid (CHA), is used for viral upper respiratory tract infection treatment caused by influenza virus, parainfluenza virus, and respiratory syncytial virus, ect in China. It was reported that CHA reduced serum hepatitis B virus level and death rate of influenza virus-infected mice. However, the underlying mechanisms of CHA against the influenza A virus have not been fully elucidated. Here, the antiviral effects and potential mechanisms of CHA against influenza A virus were investigated...
April 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28392861/reported-exercise-related-respiratory-symptoms-and-exercise-induced-bronchoconstriction-in-asthmatic-children
#19
Demet Inci, Refoel Guggenheim, Derya Ufuk Altintas, Johannes H Wildhaber, Alexander Moeller
BACKGROUND: Unlimited physical activity is one of the key issues of asthma control and management. We investigated how reliable reported exercise-related respiratory symptoms (ERRS) are in predicting exercise-induced bronchoconstriction (EIB) in asthmatic children. METHODS: In this prospective study, 179 asthmatic children aged 7 - 15 years were asked for specific questions on respiratory symptoms related to exercise and allocated into two groups according to whether they complained about symptoms...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28389949/structural-study-of-the-bacterial-flagellar-basal-body-by-electron-cryomicroscopy-and-image-analysis
#20
Akihiro Kawamoto, Keiichi Namba
The bacterial flagellum is a large assembly of about 30 different proteins and is divided into three parts: filament, hook, and basal body. The machineries for its crucial functions, such as torque generation, rotational switch regulation, protein export, and assembly initiation, are all located around the basal body. Although high-resolution structures of the filament and hook have already been revealed, the structure of the basal body remains elusive. Recently, the purification protocol for the MS ring, which is the core ring of the basal body, has been improved for the structural study of the MS ring by electron cryomicroscopy (cryoEM) and single particle image analysis...
2017: Methods in Molecular Biology
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