Adrian Allen, Ryan Magee, Ryan Devaney, Tara Ardis, Caitlín McNally, Carl McCormick, Eleanor Presho, Michael Doyle, Purnika Ranasinghe, Philip Johnston, Raymond Kirke, Roland Harwood, Damien Farrell, Kevin Kenny, Jordy Smith, Stephen Gordon, Tom Ford, Suzan Thompson, Lorraine Wright, Kerri Jones, Paulo Prodohl, Robin Skuce
Mycobacterium bovis the main agent of bovine tuberculosis (bTB), presents as a series of spatially-localised micro-epidemics across landscapes. Classical molecular typing methods applied to these micro-epidemics, based on genotyping a few variable loci, have significantly improved our understanding of potential epidemiological links between outbreaks. However, they have limited utility owing to low resolution. Conversely, whole-genome sequencing (WGS) provides the highest resolution data available for molecular epidemiology, producing richer outbreak tracing, insights into phylogeography and epidemic evolutionary history...
February 2024: Microbial Genomics