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https://www.readbyqxmd.com/read/29452833/endothelial-vascular-cell-adhesion-molecule-1-is-a-marker-for-high-risk-carotid-plaques-and-target-for-ultrasound-molecular-imaging
#1
Craig C Weinkauf, Kirsten Concha-Moore, Jonathan R Lindner, Edmund R Marinelli, Kyle P Hadinger, Sandipan Bhattacharjee, Scott S Berman, Kay Goshima, Luis R Leon, Terry O Matsunaga, Evan Unger
BACKGROUND: Molecular imaging of carotid plaque vulnerability to atheroembolic events is likely to lead to improvements in selection of patients for carotid endarterectomy (CEA). The aims of this study were to assess the relative value of endothelial inflammatory markers for this application and to develop molecular ultrasound contrast agents for their imaging. METHODS: Human CEA specimens were obtained prospectively from asymptomatic (30) and symptomatic (30) patients...
February 13, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29452629/continuous-betadine-bacitracin-irrigation-for-vascular-graft-infections-a-case-series
#2
David V Strider, Catherine R Ratliff, Kenneth J Cherry, Gilbert R Upchurch
The aim of the study was to conduct a retrospective chart review of patients who underwent betadine/bacitracin continuous irrigation (BBCI) for vascular graft infections (VGIs) to review its use as a treatment option. A retrospective chart review from 2013 to 2017 was conducted of patients with VGIs that were treated with BBCI postremoval of the infected graft. The BBCI is a continuous infusion of 0.25% betadine in normal saline at 0.3 mL/kg/h for 48 hours then followed by bacitracin infusion with a concentration of 50,000 units bacitracin/per liter normal saline at 0...
March 2018: Journal of Vascular Nursing: Official Publication of the Society for Peripheral Vascular Nursing
https://www.readbyqxmd.com/read/29451075/short-term-outcomes-of-preoperative-intra-aortic-balloon-pump-use-in-patients-undergoing-adjunctive-coronary-endarterectomy-a-retrospective-observational-study
#3
Liangshan Wang, Xing Hao, Xiaomeng Wang, Chengxiong Gu, Hong Wang, Xiaotong Hou
BACKGROUND: Coronary artery bypass grafting (CABG) combined with coronary endarterectomy (CE) can be associated with high operative mortality and morbidity. An intra-aortic balloon pump (IABP) has been the most widely used mechanical circulatory support device during perfusion treatment. However, the benefits of preoperative IABP in CABG combined with CE remain unknown. We conducted a retrospective observational study to evaluate the efficacy of preoperative IABP therapy in patients undergoing adjunctive right coronary artery (RCA) endarterectomy...
February 1, 2018: Perfusion
https://www.readbyqxmd.com/read/29450722/incidence-and-characteristics-of-chronic-thromboembolic-pulmonary-hypertension-in-germany
#4
Thorsten Kramm, Heinrike Wilkens, Jan Fuge, Hans-Joachim Schäfers, Stefan Guth, Christoph B Wiedenroth, Bettina Weingard, Doerte Huscher, David Pittrow, Serghei Cebotari, Marius M Hoeper, Eckhard Mayer, Karen M Olsson
BACKGROUND: The incidence of chronic thromboembolic pulmonary hypertension (CTEPH) is unknown. Previous studies from the United Kingdom and Spain have reported incidence rates of 1.75 and 0.9 per million, respectively. These figures, however, may underestimate the true incidence of CTEPH. METHODS: We prospectively enrolled patients newly diagnosed with CTEPH within 2016 in Germany. Data were obtained from the three German referral centers and from the German branch of COMPERA, a European pulmonary hypertension registry...
February 15, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29441169/perioperative-stroke-pathophysiology-and-management
#5
REVIEW
Sang-Bae Ko
Although perioperative stroke is uncommon during low-risk non-vascular surgery, if it occurs, it can negatively impact recovery from the surgery and functional outcome. Based on the Society for Neuroscience in Anesthesiology and Critical Care Consensus Statement, perioperative stroke includes intraoperative stroke, as well as postoperative stroke developing within 30 days after surgery. Factors related to perioperative stroke include age, sex, a history of stroke or transient ischemic attack, cardiac surgery (aortic surgery, mitral valve surgery, or coronary artery bypass graft surgery), and neurosurgery (external carotid-internal carotid bypass surgery, carotid endarterectomy, or aneurysm clipping)...
February 2018: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/29435269/current-understanding-of-chronic-total-occlusion-of-the-internal-carotid-artery
#6
Baofeng Xu, Chao Li, Yunbao Guo, Kan Xu, Yi Yang, Jinlu Yu
At present, there is limited understanding of chronic total occlusion (CTO) of the internal carotid artery (ICA). Therefore, the present report collected related cases from PubMed and reviewed the literature. Cerebral vessels may form collateral circulation immediately or gradually following CTO of the ICA. The natural history of CTO of the ICA includes a variety of outcomes, all of which are biased toward a non-benign progressive process and are characterized by insufficient cerebral perfusion, embolus detachment and cognitive dysfunction...
February 2018: Biomedical Reports
https://www.readbyqxmd.com/read/29430887/results-of-hybrid-procedures-for-treatment-of-aortoiliac-trans-atlantic-inter-society-consensus-ii-d-lesions-with-self-expanding-covered-heparin-bonded-stent-grafts
#7
Christian Uhl, Thomas Betz, Barbara Weiss, Ingolf Töpel, Markus Steinbauer
INTRODUCTION: According to the guidelines aortoiliac TASC D lesions should be treated by bypass. The purpose of this study was to examine the results of hybrid procedures with the use of a self-expanding covered heparin-bonded stent graft (Viabahn) in patients with extensive aorto-iliac lesions who were not considered to be suitable for open aorto-iliac surgery. METHODS: All patients who received a hybrid procedure in combination with a Viabahn stent in our clinic to treat aortoiliac lesions between October 2011 and April 2017 were included in this retrospective analysis...
February 8, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29428533/greater-compliance-within-instruction-for-use-ifu-for-concomitant-iliac-aneurysms-and-adverse-aneurysm-characteristics-initial-experience-with-the-nellix-endovascular-aneurysm-sealing-system-evas-at-a-single-institution
#8
J X Hing, J K Ch'ng, K H Tay, T T Chong
AIM: The Nellix was introduced to Asia in 2014. Data in Asians have been sparse. Two balloon expandable stents, each surrounded by a polymer-filled endobag are deployed in parallel to obliterate and seal the aneurysm. This paradigm shift to treating abdominal aortic aneurysms confers advantages for certain adverse aneurysm morphology that is outside the IFU for standard EVAR devices. We examine outcomes of fifteen Asian patients with concomitant infrarenal aortic and iliac artery aneurysms treated with the Nellix at our institution...
February 8, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29426593/an-updated-systematic-review-and-meta-analysis-of-outcomes-following-eversion-vs-conventional-carotid-endarterectomy-in-randomised-controlled-trials-and-observational-studies
#9
REVIEW
Kosmas I Paraskevas, Vaux Robertson, Athanasios N Saratzis, A Ross Naylor
INTRODUCTION: A 2011 meta-analysis comparing eversion (eCEA) with conventional (cCEA) carotid endarterectomy in 16,251 patients concluded that eCEA was associated with lower rates of peri-operative stroke and late occlusion compared with cCEA. However, randomised controlled trials (RCTs) showed no difference in outcomes. Since then, the literature contains outcome data on 49,500 patients undergoing eCEA or cCEA. An updated meta-analysis was performed to establish whether eCEA confers significant benefit over cCEA...
February 6, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29424201/hereditary-hyperhomocysteinemia-associated-with-nephrotic-syndrome-complicated-by-artery-thrombosis-and-chronic-thromboembolic-pulmonary-hypertension-a-case-report
#10
Paolo Ruggeri, Federica Lo Bello, Francesco Nucera, Michele Gaeta, Francesco Monaco, Gaetano Caramori, Giuseppe Girbino
We present here the case of a 30-year-old man with a long term history of nephrotic syndrome (NS) who developed an episode of acute left main pulmonary artery thrombosis complicated by a lung abscess. During the hospital admission was also identified a concomitant hyperhomocysteinemia. After an atypical resection of the left upper pulmonary lobe and the starting of long term anticoagulation the patient was discharged but did not attend the planned follow up visits until one year later when he was seen again for severe dyspnea and exercise intolerance...
December 19, 2017: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/29422277/revascularization-of-radiation-induced-carotid-artery-stenosis-with-carotid-endarterectomy-vs-carotid-artery-stenting-a-systematic-review-and-meta-analysis
#11
REVIEW
Stefanos Giannopoulos, Pavlos Texakalidis, Anil Kumar Jonnalagadda, Theofilos Karasavvidis, Spyridon Giannopoulos, Damianos G Kokkinidis
OBJECTIVE: The incidence of carotid artery stenosis after head and neck radiation is anticipated to rise due to the increasing survival of patients with head and neck malignancies. It remains unclear whether carotid artery stenting (CAS) or endarterectomy (CEA) is the best treatment strategy for radiation-induced carotid artery stenosis. MATERIALS & METHODS: This study was performed according to the PRISMA and MOOSE guidelines. Eligible studies were identified through a comprehensive search of PubMed, Scopus and Cochrane Central until July 20, 2017...
January 31, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29417939/apolipoprotein-j-as-a-predictive-biomarker-for-restenosis-after-carotid-endarterectomy-a-retrospective-study
#12
Anastasios Maskanakis, Nikolaos Patelis, Georgios Karaolanis, Spyridon Davakis, Dimitrios Schizas, Despina Perrea, Chris Klonaris, Sotirios Georgopoulos, Theodoros Liakakos, Chris Bakoyiannis
Carotid endarterectomy (CEA) is an effective surgical option for stroke prophylaxis in most patients. Restenosis after CEA can lead to re-intervention and adverse events, but the factors predicting restenosis are poorly understood. Apolipoprotein J (ApoJ) is considered to be a novel predictive factor of vascular restenosis and is associated with a large number of processes related to atherosclerosis and cell-cycle phases. The aim of this study was to elucidate the predictive value of Apo J in internal carotid artery (ICA) restenosis following CEA...
February 8, 2018: Acta Pharmacologica Sinica
https://www.readbyqxmd.com/read/29416470/bilateral-bispectral-index-monitoring-to-detect-cerebral-hypoperfusion-during-carotid-endarterectomy-under-general-anesthesia
#13
Jin Xi Zheng
The bilateral use of bispectral index (BIS) monitoring in a 68-year-old male who underwent right carotid endarterectomy (CEA) under general anesthesia (GA) is described. During three episodes of right internal carotid artery cross-clamping intraoperatively, the right BIS value rose relative to the left within 1 min of clamping, followed by a return to baseline within 1-2 min of clamp release. Since unilateral BIS values can decrease or increase in response to cross-clamping, a significant difference in left and right BIS values may provide a simple and easily available method to detect cerebral hypoperfusion during CEA under GA...
January 2018: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/29409700/commentary-on-an-updated-systematic-review-and-meta-analysis-of-outcomes-following-eversion-vs-conventional-carotid-endarterectomy-in-randomised-controlled-trials-and-observational-studies
#14
Jean-Baptiste Ricco, Nabil Chakfe
No abstract text is available yet for this article.
February 3, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29405249/distinctive-peri-luminal-presence-of-agrin-in-murine-and-human-carotid-atherosclerotic-plaques
#15
Uwe Rauch, Eva Bengtsson, Isabel Gonçalves, Anna Hultgårdh-Nilsson
The clinical consequences of arterial atherosclerotic lesions depend, apart from their size, on their composition of cellular and extracellular components. While an intact endothelium at the interface of atherosclerotic plaques towards the blood can prevent its erosion, underlying smooth muscle cells within the plaque can reduce the risk of plaque ruptures, due to the deposition of stabilizing extracellular matrix. Basement membranes underlay and support the function of endothelial cells, and embed smooth muscle cells in the media, the source of most smooth muscle cells within atherosclerotic plaques...
February 6, 2018: Histology and Histopathology
https://www.readbyqxmd.com/read/29402768/spotty-carotid-plaques-are-associated-with-inflammation-and-the-occurrence-of-cerebrovascular-symptoms
#16
Sanela Halak, Gerd Östling, Andreas Edsfeldt, Cecilia Kennbäck, Magnus Dencker, Isabel Gonçalves, Giuseppe Asciutto
BACKGROUND: Echolucent carotid plaques have been related to an increased risk of ischemic cerebrovascular events. The aim of the present study was to evaluate whether a new objective ultrasonographic parameter, the statistical geometric feature (SGF), reflecting spottiness of carotid plaques, can be associated with cerebrovascular symptoms and with a rupture-prone plaque phenotype. METHODS: The plaques of 144 patients who underwent carotid endarterectomy were included in this study...
January 15, 2018: Cerebrovascular Diseases Extra
https://www.readbyqxmd.com/read/29402628/total-intravenous-versus-volatile-induction-and-maintenance-of-anesthesia-in-elective-carotid-endarterectomy-effects-on-cerebral-oxygenation-and-cognitive-functions
#17
Vsevolod V Kuzkov, Maxim Y Obraztsov, Oleg Y Ivashchenko, Nadezhda Y Ivashchenko, Valery M Gorenkov, Mikhail Y Kirov
OBJECTIVE: Carotid endarterectomy (CEA) is effective for the prevention of stroke, yet can be associated with a postoperative cognitive dysfunction (POCD) that may be affected by the type of anesthesia. The aim of the study was to compare the effects of total intravenous anesthesia (TIVA) with propofol to volatile induction and maintenance of anesthesia (VIMA) with sevoflurane on cerebral tissue oxygen saturation (SctO2) and POCD. DESIGN: Single-center, pilot randomized prospective study...
January 5, 2018: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29398378/systolic-anterior-motion-of-the-mitral-valve-during-pulmonary-endarterectomy-in-a-patient-with-chronic-thromboembolic-pulmonary-hypertension-a-case-report
#18
Koji Hoshino, Koichi Takita, Masami Demura, Tomonori Kubo, Yuji Morimoto
No abstract text is available yet for this article.
June 16, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29397311/cerebral-neuromonitoring-during-carotid-endarterectomy-and-impact-of-contralateral-internal-carotid-occlusion
#19
Davorin Sef, Andrija Skopljanac-Macina, Milan Milosevic, Anita Skrtic, Vinko Vidjak
BACKGROUND: The aim of this study was to identify the reliability of carotid artery stump pressure (SP) in predicting the neurologic changes and correlation with contralateral internal carotid artery (ICA) occlusion in patients undergoing eversion carotid endarterectomy (CEA). The optimal method for monitoring cerebral perfusion during CEA, performed under either local or general anesthesia, is still controversial. METHODS: We prospectively analyzed 118 consecutive patients undergoing eversion CEA under local anesthesia...
January 31, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29397291/a-randomized-controlled-trial-examining-the-effect-of-the-addition-of-the-mandibular-block-to-cervical-plexus-block-for-carotid-endarterectomy
#20
Nilgun Kavrut Ozturk, Ali Sait Kavakli, Kadir Sagdic, Kerem Inanoglu, Raif Umot Ayoglu
OBJECTIVES: Although the cervical plexus block generally provides adequate analgesia for carotid endarterectomy, pain caused by metal retractors on the inferior surface of the mandible is not prevented by the cervical block. Different pain relief methods can be performed for patients who experience discomfort in these areas. In this study, the authors evaluated the effect of mandibular block in addition to cervical plexus block on pain scores in carotid endarterectomy. DESIGN: A prospective, randomized, controlled trial...
June 20, 2017: Journal of Cardiothoracic and Vascular Anesthesia
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