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S Das, P L Haroled Peter, M Lakshmi Bhavani, P Naresh, M V Ramana
A cross-sectional study of 250 cases of type 2 diabetes management was conducted in a governmental tertiary care hospital of urban south India to determine the comparative prevalence of type 2 diabetes and its comorbidity with cardiovascular diseases in diabetic population, core drug use indicators and drug utilization pattern in the management of diabetics entirely and with cardiovascular diseases. Highest prevalent age group for type 2 diabetes/cardiovascular diseases (greater incidence in female than male) was 51-60 years...
July 2015: Indian Journal of Pharmaceutical Sciences
Ivan Nikiforov, Qurat Mansoora, Hassan Al-Khalisy, Sarah Joseph, Pramil Cheriyath
Background. Scrotal swelling is a rare complication of acute pancreatitis with few reported cases in the literature. In this case report, we present a 59-year-old male with hydrochlorothiazide induced pancreatitis who developed scrotal swelling. Case Presentation. A 59-year-old male presented to the emergency department with sharp epigastric abdominal pain that radiated to the back and chest. On physical examination, he had abdominal tenderness and distention with hypoactive bowel sounds. Computed tomography (CT) scan of the abdomen showed acute pancreatitis...
2015: Case Reports in Gastrointestinal Medicine
Mansoor Ahmad, Nudrat Adil
Compatibility and stability of the polygeline-based blood plasma expander/plasma substitute Haemaccel with different drug products i.e., Profenid, Stemetil, and Lasix were examined in the context of its potential use in surgical, spinal, septic shock and in circulatory insufficiency, because treatment, safety, acceptability and efficacy of drug product may be affected by drug instability or incompatibility. Therefore, drug stability and compatibility are critical elements in accurate and appropriate delivery of drug therapy to patients...
November 2014: Pakistan Journal of Pharmaceutical Sciences
Andrew B Rosenkrantz, Arjun V Balar, William C Huang, Kimberly Jackson, Kent P Friedman
PURPOSE: The aim of this study was to compare coregistration of the bladder wall, bladder masses, and pelvic lymph nodes between sequential and simultaneous PET and MRI acquisitions obtained during hybrid (18)F-FDG PET/MRI performed using a diuresis protocol in bladder cancer patients. METHODS: Six bladder cancer patients underwent (18)F-FDG hybrid PET/MRI, including IV Lasix administration and oral hydration, before imaging to achieve bladder clearance. Axial T2-weighted imaging (T2WI) was obtained approximately 40 minutes before PET ("sequential") and concurrently with PET ("simultaneous")...
August 2015: Clinical Nuclear Medicine
Des P Leadon
No abstract text is available yet for this article.
November 2014: Veterinary Journal
Marcelo Di Gregorio, Andrei Botnaru, Laurent Bairy, Francis Lorge
BACKGROUND: The treatment of symptomatic uretropelvic junction obstruction (UPJO) has evolved towards minimal invasive endourologic and laparoscopic techniques. Robotic assisted laparoscopic pyeloplasty has achieved outcomes comparable to those corresponding to open and laparoscopic techniques. The objective of this work is to demonstrate that the transition between open to robotic surgeries is straightforward. We analysed retrospectively "our initial results" in robotic assisted UPJ reconstruction procedures...
2014: SpringerPlus
Brendan Heffron, Marc Benoit, Jennifer Bishop, Sara Costello, Laura Hurt, Lindsay Simpson, Lisa Taddei, Kevin Kline, Adam Negrusz
During prolonged strenuous exercise, racehorses can experience acidemia. To counteract this phenomenon, trainers can administer blood alkalizing agents that raise the plasma pH and total carbon dioxide (TCO2) concentration. In Illinois, the administrative threshold for TCO2 in plasma is 37.0 mmol/L. Because accuracy in the reported measurement of TCO2 must be ensured, uncertainty measurements are often issued alongside the reported concentrations. We report a validated method for measuring TCO2 levels in equine plasma using the Beckman UniCel DxC 600...
October 2014: Journal of Analytical Toxicology
Dominic Lee, Richard E Link
OBJECTIVE: To aid in counseling and managing a challenging patient cohort, we review our experience using a structured endoscopic approach to assess individuals with recurrent symptoms but a normal anatomic evaluation after pyeloplasty. METHODS: From 2008 to 2012, all patients presenting with recurrent symptoms after pyeloplasty for ureteropelvic junction (UPJ) obstruction were retrospectively evaluated. After baseline renal scanning, all underwent retrograde ureteropyelography, flexible ureteroscopy, UPJ balloon calibration, and provocative ureteral stenting...
July 2014: Urology
Antonio Cusano, Fernando Abarzua-Cabezas, Stuart Kesler
A 57-year-old woman presented with bilateral abdominal pain and flank discomfort. Imaging studies, consisting of CT scan, diethylene triamine pentaacetic acid renal scan with Lasix and a retrograde pyelogram, indicated an obstruction at the uteropelvic junction (UPJ), possibly due to fibroepithelial polyps within the ureter. A robotic pyeloplasty revealed a ureteral diverticulum and a thin, still-attached fibroepithelial polyp of approximately 2 cm in length. The patient tolerated the procedure well and was discharged one day postpyeloplasty with no reported complications...
2014: BMJ Case Reports
Mansoor Ahmad, Sadaf Sharif, Mehjabeen, Hina Sharif, Noor Jahan, Ghazala Raza Naqvi
The Dolichos biflorus is a well known medicinal plant in folklore for its medicinal properties. In herbal medicine the seeds of it are mainly used as tonic, astringent, diuretic, and are also recommended in asthma, bronchitis, urinary discharges, hiccoughs, ozoena, heart trouble and other diseases of brain. The main purpose of this study is to explore and to provide experimental data on the traditional use of plant Dolichos biflorus. For this purpose we investigated the plant seed extract phytochemically and pharmacologically...
March 2014: Pakistan Journal of Pharmaceutical Sciences
Rosa M Romero, Jose Maria Angulo, Alberto Parente, Susana Rivas, Ana Rosa Tardáguila
BACKGROUND AND PURPOSE: There is a growing interest in minimally invasive treatment of primary obstructive megaureter (POM) in children. The absence of long-term follow-up data, however, makes it difficult to establish the indication for an endoscopic approach. The aim of our study is to determine the long-term efficacy of endourologic high-pressure balloon dilation of the vesicoureteral junction (VUJ) in children with POM that necessitates surgical treatment. METHODS: We retrospectively reviewed the clinical records from children with POM who were treated with endourologic high-pressure balloon dilation of the VUJ from March 2003 to April 2010...
May 2014: Journal of Endourology
Andrea G Lantz, Michael Ordon, Kenneth T Pace, R John D'A Honey
PURPOSE: Success after laparoscopic pyeloplasty (LP) for ureteropelvic junction obstruction is determined based on renal scan (RS) results and patient symptoms ± ultrasonography. The upright or prone position during RS may facilitate drainage. This study reports on outcomes after LP and robot-assisted pyeloplasty (RALP) and determines if patient position (supine vs prone) alters the results of the postoperative RS and surgical "success." PATIENTS AND METHODS: A retrospective review of LP and RALP performed by one surgeon between 2005 and 2012 was performed...
December 2013: Journal of Endourology
Andrea Gail Lantz, Michael Ordon, Kenneth T Pace, R John D'A Honey
Purpose: Success following laparoscopic pyeloplasty (LP) for ureteropelvic junction (UPJ) obstruction is determined based on renal scan (RS) results and patient symptoms ± ultrasound. The upright or prone position during RS may facilitate drainage. This study reports on outcomes following LP and robotic-assisted pyeloplasty (RALP) and determines if patient position (supine vs. prone) alters the results of the postoperative RS and surgical "success". Materials and Methods: A retrospective review of LP and RALP performed by one surgeon between 2005-2012 was performed...
September 2, 2013: Journal of Endourology
Heather E Elser
No abstract text is available yet for this article.
December 2012: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
Colin Cordemans, Inneke De Laet, Niels Van Regenmortel, Karen Schoonheydt, Hilde Dits, Greg Martin, Wolfgang Huber, Manu Lng Malbrain
INTRODUCTION: Achievement of a negative fluid balance in patients with capillary leak is associated with improved outcome. We investigated the effects of a multi-modal restrictive fluid strategy aiming for negative fluid balance in patients with acute lung injury (ALI). METHODS: In this retrospective matched case-control study, we included 114 mechanically ventilated (MV) patients with ALI. We compared outcomes between a group of 57 patients receiving PAL-treatment (PAL group) and a matched control group, abstracted from a historical cohort...
July 5, 2012: Annals of Intensive Care
Andrew D Krystal, Janice Sutherland, Daryl W Hochman
A number of antiepileptic medications that modulate GABA(A) mediated synaptic transmission are anxiolytic. The loop diuretics furosemide (Lasix) and bumetanide (Bumex) are thought to have antiepileptic properties. These drugs also modulate GABA(A) mediated signalling through their antagonism of cation-chloride cotransporters. Given that loop diuretics may act as antiepileptic drugs that modulate GABAergic signalling, we sought to investigate whether they also mediate anxiolytic effects. Here we report the first investigation of the anxiolytic effects of these drugs in rat models of anxiety...
2012: PloS One
Valeria Ambrogi, Luana Perioli, Cinzia Pagano, Fabio Marmottini, Maurizio Ricci, Anna Sagnella, Carlo Rossi
The objective of this research was to realize a new oral solid dosage form in order to improve the release of furosemide (FURO) in its preferential absorption region. In fact FURO is a drug labeled in class IV of the Biopharmaceutical Classification System (BCS) characterized by low and variable bioavailability due to both low solubility and low permeability and because of its weakly acid nature is preferentially absorbed in the stomach whereas its solubility is hampered. FURO was included in the mesoporous silica material SBA-15 obtaining an inorganic-organic compound fully characterized by: thermogravimetric analysis (TGA), X-ray Powder Diffraction (XRPD), Differential Scanning Calorimetry (DSC), Fourier Transform Infrared Spectroscopy (FT-IR) and nitrogen adsorption-desorption analysis and then submitted to in vitro dissolution...
May 12, 2012: European Journal of Pharmaceutical Sciences
V M Baranov, Iu A Popova, A S Kovalev, M V Baranov
The investigation was aimed at studying the mechanisms for change in the respiration center sensitivity in consequence of 21-hr bed rest with head-end tilted at -15 degrees combined with liquid loss (lasix, 20 ml) and recovery (IV infucol and glucose). Time of maximal breath-holding, capillary and venous O2 and CO2 pressure values were measured in the baseline data collection period, during and shortly after BR. Data analysis showed that extension of the maximal breath-holding time both during inspiration and expiration was statistically significant in the initial 10 minutes of tilting...
July 2011: Aviakosmicheskaia i Ekologicheskaia Meditsina, Aerospace and Environmental Medicine
Annie Imbeault, Frédéric Pouliot, David S Finley, Brian Shuch, Thierry Dujardin
PURPOSE: To compare en bloc and artery-only clamping techniques on renal function and perioperative outcomes after laparoscopic partial nephrectomy (LPN). PATIENTS AND METHODS: From March 2003 to December 2008, 205 patients underwent LPN by one surgeon in a single institution. The first 103 LPNs were achieved with artery-only clamping (AO), and the last 102 LPNs were realized under control of the renal hilum (artery and vein [AV] clamping). Renal function was evaluated by creatinine changes, estimation of the glomerular filtration rate (eGFR), and assessment of split renal function using renal mercaptoacetyl triglycine-Lasix scintigraphy...
May 2012: Journal of Endourology
Katherine Moore, Stéphane Bolduc
OBJECTIVES: To prospectively evaluate the efficacy of endoscopic injection in the adult population with vesicoureteral reflux (VUR). The search for VUR is a part of the standard workup of children with febrile urinary tract infections. However, VUR can present later in life and should be investigated in the case of recurrent pyelonephritis. METHODS: From 2005 to 2009, 27 postpubertal patients (3 males and 24 females) were treated endoscopically with injection of polydimethylsiloxane (Macroplastique) in 13 or dextranomer/hyaluronic acid copolymer (Deflux) in 14 patients; 41 renal units were injected...
June 2011: Urology
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