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Atheroscelerosis

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https://www.readbyqxmd.com/read/12349904/protective-role-of-magnesium-in-cardiovascular-diseases-a-review
#1
REVIEW
Sajal Chakraborti, Tapati Chakraborti, Malay Mandal, Amritlal Mandal, Sudip Das, Samarendranath Ghosh
A considerable number of experimental, epidemiological and clinical studies are now available which point to an important role of Mg2+ in the etiology of cardiovascular pathology. In human subjects, hypomagnesemia is often associated with an imbalance of electrolytes such as Na+, K+ and Ca2+. Abnormal dietary deficiency of Mg2+ as well as abnormalities in Mg2+ metabolism play important roles in different types of heart diseases such as ischemic heart disease, congestive heart failure, sudden cardiac death, atheroscelerosis, a number of cardiac arrhythmias and ventricular complications in diabetes mellitus...
September 2002: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/8973780/prevalence-of-carotid-atherosclerosis-in-hypertension-preliminary-baseline-data-from-the-european-lacidipine-study-on-atheroscelerosis-elsa
#2
RANDOMIZED CONTROLLED TRIAL
A Zanchetti
In the ELSA trial, the effects of lacidipine-based treatment and beta-blocker (atenolol)-based treatment on the development and progression of carotid wall alterations are assessed in hypertensive patients. The primary endpoint of this study is the rate of change in the intima-media thickness of the carotid artery wall, measured with B-mode ultrasound. About 2300 hypertensive patients have been recruited and randomized to either of the antihypertensive agents. Baseline data for 1965 patients are available, showing a high prevalence of carotid wall lesions: about 82% of the subjects have an intima-media thickness > or = 1...
1996: Blood Pressure. Supplement
https://www.readbyqxmd.com/read/8835323/common-genetic-variants-of-lipoprotein-lipase-that-relate-to-lipid-transport-in-patients-with-premature-coronary-artery-disease
#3
Q Zhang, J Cavanna, B R Winkelman, B Shine, W Gross, W Marz, D J Galton
Two common coding sequence mutations of lipoprotein lipase (serine447-ter, producing a carboxy terminal truncation; and asp9-asn variants) were studied in 329 Caucasian subjects, of whom 243 had angiographic features of premature atheroscelerosis (220 with coronary artery disease; 23 with coronary and peripheral artery disease). As expected, the mean levels of cholesterol, triglycerides, LDL-cholesterol, ApoB and Lp(a) were significantly higher in the arterial disease group than in the controls. HDL levels were lower in the patient group...
December 1995: Clinical Genetics
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