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Relative wall thickness

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https://www.readbyqxmd.com/read/28732106/specific-%C3%AE-7-nicotinic-acetylcholine-receptor-agonist-ameliorates-isoproterenol-induced-cardiac-remodeling-in-mice-through-tgf-%C3%AE-1-smad3-pathway
#1
Yong-Hua Yang, Huan-Le Fang, Ming Zhao, Xiang-Lan Wei, Ning Zhang, Shun Wang, Yi Lu, Xiao-Jiang Yu, Lei Sun, Xi He, Dong-Ling Li, Jin-Jun Liu, Wei-Jin Zang
It is well-accepted that inflammation plays an important role in the development of cardiac remodeling and that therapeutic approaches targeting inflammation can inhibit cardiac remodeling. Although a large amount of evidence indicates that activation of α7 nicotinic acetylcholine receptor (α7nAChR) causes an anti-inflammatory effect, the role of α7nAChR in cardiac remodeling and the underlying mechanism have not been established. To investigate the effect of the specific α7nAChR agonist, PNU282987, on cardiac remodeling induced by isoproterenol (ISO 60 mg/kg/d) in mice, the cardiomyocyte cross-sectional area (CSA) and collagen volume fraction were evaluated by hematoxylin and eosin (HE) and Masson staining, respectively...
July 21, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/28726244/computed-tomographic-morphometry-of-tympanic-bulla-shape-and-position-in-brachycephalic-and-mesaticephalic-dog-breeds
#2
Ben Mielke, Richard Lam, Gert Ter Haar
Anatomic variations in skull morphology have been previously described for brachycephalic dogs; however there is little published information on interbreed variations in tympanic bulla morphology. This retrospective observational study aimed to (1) provide detailed descriptions of the computed tomographic (CT) morphology of tympanic bullae in a sample of dogs representing four brachycephalic breeds (Pugs, French Bulldogs, English Bulldog, and Cavalier King Charles Spaniels) versus two mesaticephalic breeds (Labrador retrievers and Jack Russell Terriers); and (2) test associations between tympanic bulla morphology and presence of middle ear effusion...
July 20, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28724650/dynamic-relation-of-changes-in-weight-and-indices-of-fat-distribution-with-cardiac-structure-and-function-the-dallas-heart-study
#3
Bryan Wilner, Sonia Garg, Colby R Ayers, Christopher D Maroules, Roderick McColl, Susan A Matulevicius, James A de Lemos, Mark H Drazner, Ronald Peshock, Ian J Neeland
BACKGROUND: Obesity may increase heart failure risk through cardiac remodeling. Cross-sectional associations between adiposity and cardiac structure and function have been elucidated, but the impact of longitudinal changes in adiposity on cardiac remodeling is less well understood. METHODS AND RESULTS: Participants in the Dallas Heart Study without cardiovascular disease or left ventricular dysfunction underwent assessment of body weight, anthropometrics, and cardiac magnetic resonance imaging at baseline and 7 years later...
July 19, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28724040/cardiac-remodeling-indicators-in-adolescent-athletes
#4
Joaquim Castanheira, João Valente-Dos-Santos, Daniela Costa, Diogo Martinho, Jorge Fernandes, João Duarte, Nuno Sousa, Vasco Vaz, Luis Rama, António Figueiredo, Manuel Coelho-E-Silva
Objective: The idea that different sports and physical training type results in different cardiac adaptations has been widely accepted. However, this remodelling process among different sport modalities is still not fully understood. Thus, the current study aims to investigate the heart morphology variation associated with a set of different modalities characterized by distinct models of preparation and different methods and demands of training and completion. Method: The sample comprises 42 basketball players, 73 roller hockey players, 28 judo athletes and 21 swimmers...
May 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28722090/-evaluation-of-a-new-closure-technique-of-large-defects-after-endoscopic-full-thickness-resection
#5
Xiao Liu, Lizhou Dou, Yong Liu, Shun He, Yueming Zhang, Xinying Yu, Yan Ke, Xudong Liu, Ruigang Wang, Guiqi Wang
OBJECTIVE: To investigate the security and efficacy of a new endoscopic closure method of large defects after endoscopic full-thickness resection (EFTR) double purse-string suture using two endoloops and metallic clips via single-channel endoscopy. METHODS: Clinical data of 23 cases with submucosal tumors (SMT) who received endoscopic resection from June 2015 to July 2016 in our National Cancer Center were collected. For gastric and esophageal SMTs or the mucosa layer injured during submucosal tunneling endoscopic resection (STER), double purse-string suture was conducted after EFTR...
July 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28721665/micro-computed-tomography-characterization-of-tissue-engineering-scaffolds-effects-of-pixel-size-and-rotation-step
#6
Ibrahim Fatih Cengiz, Joaquim Miguel Oliveira, Rui L Reis
Quantitative assessment of micro-structure of materials is of key importance in many fields including tissue engineering, biology, and dentistry. Micro-computed tomography (µ-CT) is an intensively used non-destructive technique. However, the acquisition parameters such as pixel size and rotation step may have significant effects on the obtained results. In this study, a set of tissue engineering scaffolds including examples of natural and synthetic polymers, and ceramics were analyzed. We comprehensively compared the quantitative results of µ-CT characterization using 15 acquisition scenarios that differ in the combination of the pixel size and rotation step...
August 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28719956/a-case-of-ectopic-peritoneal-paragonimiasis-mimicking-diverticulitis-or-abdominal-abscess
#7
Min Jae Kim, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Yong Sik Yoon, Kyung Won Kim, Jaeeun Cho, Jong-Yil Chai, Yong Pil Chong
Paragonimiasis is a parasitic disease caused by Paragnonimus species. The primary site of infection is the lung, and extrapulmonary involvement is also reported. When infected with Paragonimus westermani, which is the dominant species in Korea, the central nervous system is frequently involved along with the liver, intestine, peritoneal cavity, retroperitoneum, and abdominal wall. Ectopic paragonimiasis raises diagnostic challenge since it is uncommon and may be confused with malignancy or other inflammatory diseases...
June 2017: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/28713910/anti-obesity-effects-of-yellow-catfish-protein-hydrolysate-on-mice-fed-a-45-kcal-high-fat-diet
#8
Mi-Ryung Kim, Joo-Wan Kim, Jeong Been Park, Yong-Ki Hong, Sae Kwang Ku, Jae-Suk Choi
Obesity contributes to the etiologies of a variety of comorbid conditions, such as type 2 diabetes, hypertension and cardiovascular disease. In the present study, the anti-obesity effects of yellow catfish protein hydrolysate (YPh) were observed in mice fed a 45% kcal high-fat diet (HFD) compared with those of mice treated with simvastatin. The HFD-fed control mice exhibited noticeable increase in body weight, and whole-body and abdominal fat densities, periovarian and abdominal wall-deposited fat pad weight, as well as in the levels of triglycerides (TG), blood total cholesterol (TC), low-density lipoprotein, alanine aminotransferase, aspartate aminotransferase, creatinine, blood urea nitrogen, and in the fecal TG and TC contents...
July 10, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28711694/normal-ultrasonographic-reference-values-for-the-gastrointestinal-tract-in-developing-puppies
#9
Tommaso Banzato, Chiara Milani, Elena Zambello, Alessandro Zotti
Thickness of the individual layers of the wall of the stomach, duodenum, jejunum and colon was assessed by means of ultrasonography in developing puppies at 4, 8 and 16weeks of age. Reference intervals for the thickness of individual ultrasonographic layers of the stomach, duodenum, jejunum and colon at different ages are reported. An increase in wall thickness of all the examined gastro-intestinal tracts in relation to age was recorded. The effect of body-weight was stronger on duodenal and jejunal thickness whereas it resulted lesser on stomach and colon...
July 9, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28705193/spatial-regulation-of-monolignol-biosynthesis-and-laccase-genes-control-developmental-and-stress-related-lignin-in-flax
#10
Julien Le Roy, Anne-Sophie Blervacq, Anne Créach, Brigitte Huss, Simon Hawkins, Godfrey Neutelings
BACKGROUND: Bast fibres are characterized by very thick secondary cell walls containing high amounts of cellulose and low lignin contents in contrast to the heavily lignified cell walls typically found in the xylem tissues. To improve the quality of the fiber-based products in the future, a thorough understanding of the main cell wall polymer biosynthetic pathways is required. In this study we have carried out a characterization of the genes involved in lignin biosynthesis in flax along with some of their regulation mechanisms...
July 14, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/28700437/adenomyoma-with-pseudoinvasive-growth-pattern-and-serosal-penetration-mimicking-endometrial-carcinoma
#11
Thomas Raj, Robert DeWitt, Nathaniel E Smith
We present a novel case of a 48-yr-old female with a uterine adenomyoma with an unusual pseudoinvasive growth pattern displaying full-thickness penetration beyond the serosal surface in association with a dehisced Caesarian scar. Before hysterectomy, magnetic resonance imaging findings showed an infiltrative lesion suggestive of endometrial carcinoma. An endometrial biopsy was benign but definitive operative management was pursued given the concerning imaging. Gross examination of the uterus demonstrated a 7...
July 11, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28697895/a-neonatal-rat-model-of-increased-right-ventricular-afterload-by-pulmonary-artery-banding
#12
Shoubao Wang, Lincai Ye, Haifa Hong, Chao Tang, Minghui Li, Zhen Zhang, Jinfen Liu
OBJECTIVE: To construct a neonatal rat model of increased right ventricular (RV) afterload for studying the pathophysiological remodeling of the right ventricle in patients with congenital heart disease with increased RV afterload. METHODS: Surgery was performed within 6 hours after birth. Horizontal thoracotomy was performed by dissecting the intercostal muscles and splitting the sternum. The PA was then banded with 11-0 nylon thread. At postnatal day 7 (P7), constriction of PA was confirmed by echocardiography...
June 13, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28696150/curative-intent-radical-en-bloc-resection-using-a-minimum-of-a-3%C3%A2-cm-margin-in-feline-injection-site-sarcomas-a-retrospective-analysis-of-131-cases
#13
Nina Müller, Martin Kessler
Objectives Owing to its highly infiltrative growth, feline injection-site sarcoma (FISS) carries a significant risk of local tumour recurrence. Parameters of possible prognostic significance (eg, tumour size and location, resection of de novo vs recurrent tumours, and achievement of tumour-free surgical margins) were examined with regard to their influence on recurrence rate (RR), disease-free interval (DFI) and survival time (ST). Methods This was a retrospective analysis of cats with FISSs located on the chest or abdominal wall or the interscapular region treated in a single institution using a standardised radical resection technique with 3 cm lateral margins and full-thickness body wall resection (tumours over chest/abdominal wall) or a minimum of two fascial planes (interscapular tumours)...
July 1, 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28692307/association-of-the-344t-c-polymorphism-in-aldosterone-synthase-gene-promoter-with-left-ventricular-structure-in-chinese-han-a-meta-analysis
#14
Chengqian Yin, Wei Gu, Yun Gao, Zhao Li, Xuanzu Chen, Zhizhong Li, Shaojun Wen
No consensus view has been published on the relationship between the aldosterone synthase gene (CYP11B2) -344C/T polymorphism and left ventricular hypertrophy (LVH) in Chinese Han. We undertook a meta-analysis to investigate the potential association of this polymorphism and left ventricular structure-related phenotypes, including left ventricular mass (LVM), left ventricular mass index (LVMI), left ventricular end systolic diameter (LVESD), left ventricular end diastolic dimension (LVEDD), left ventricular posterior wall thickness (LVPWT), and interventricular septal wall thickness (IVS)...
July 10, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28687796/long-range-stripe-nanodomains-in-epitaxial-110-bifeo3-thin-films-on-100-ndgao3-substrate
#15
Yogesh Sharma, Radhe Agarwal, Charudatta Phatak, Bumsoo Kim, Seokwoo Jeon, Ram S Katiyar, Seungbum Hong
Here, we report the observation of ferroelectric and ferroelastic nanodomains in (110)-oriented BiFeO3 (BFO) thin films epitaxially grown on low symmetric (100) NdGaO3 (NGO) substrate. We observed long range ordering of ferroelectric 109° stripe nanodomains separated by periodic vertical domain walls in as-grown 130 nm thick BFO films. The effect of La0.67Sr0.33CoO3 (LSCO) conducting interlayer on domain configurations in BFO/NGO film was also observed with relatively short range-ordering of stripe domains due to the modified electrostatic boundary conditions in BFO/LSCO/NGO film...
July 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28687586/a-rash-with-a-heavy-heart
#16
Sergio Barros-Gomes, Niyada Naksuk, Dragan Jevremovic, Hector R Villarraga
Cardiac amyloidosis (CA) is relatively rare and frequently misdiagnosed. Other disorders presenting with increased left ventricular (LV) mass can mimic its diagnosis. This case illustrates unique findings of primary light chain (AL) amyloidosis in a patient with remarkable signs of CA. Here, we report a 49-year-old man with prior diagnosis of hypertrophy cardiomyopathy (HCM) based on an echocardiogram performed 1 year earlier that presented with 8 weeks of periorbital rash. He had numbness in the past 3 years...
July 7, 2017: Echo Research and Practice
https://www.readbyqxmd.com/read/28681509/akt2-ablation-prolongs-life-span-and-improves-myocardial-contractile-function-with-adaptive-cardiac-remodeling-role-of-sirt1-mediated-autophagy-regulation
#17
Jun Ren, Lifang Yang, Li Zhu, Xihui Xu, Asli F Ceylan, Wei Guo, Jian Yang, Yingmei Zhang
Aging is accompanied with unfavorable geometric and functional changes in the heart involving dysregulation of Akt and autophagy. This study examined the impact of Akt2 ablation on life span and cardiac aging as well as the mechanisms involved with a focus on autophagy and mitochondrial integrity. Cardiac geometry, contractile, and intracellular Ca(2+) properties were evaluated using echocardiography, IonOptix(®) edge-detection and fura-2 techniques. Levels of Sirt1, mitochondrial integrity, autophagy, and mitophagy markers were evaluated using Western blot...
July 5, 2017: Aging Cell
https://www.readbyqxmd.com/read/28679397/local-coronary-wall-eccentricity-and-endothelial-function-are-closely-related-in-patients-with-atherosclerotic-coronary-artery-disease
#18
Allison G Hays, Micaela Iantorno, Michael Schär, Monica Mukherjee, Matthias Stuber, Gary Gerstenblith, Robert G Weiss
BACKGROUND: Coronary endothelial function (CEF) in patients with coronary artery disease (CAD) varies among coronary segments in a given patient. Because both coronary vessel wall eccentricity and coronary endothelial dysfunction are predictors of adverse outcomes, we hypothesized that local coronary endothelial dysfunction is associated with local coronary artery eccentricity. METHODS: We used 3 T coronary CMR to measure CEF as changes in coronary cross-sectional area (CSA) and coronary blood flow (CBF) during isometric handgrip exercise (IHE), a known endothelial-dependent stressor, in 29 patients with known CAD and 16 healthy subjects...
July 6, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/28676685/understanding-the-role-of-damping-and-dzyaloshinskii-moriya-interaction-on-dynamic-domain-wall-behaviour-in-platinum-ferromagnet-nanowires
#19
J Brandão, S Azzawi, A T Hindmarch, D Atkinson
Heavy metal layers, exemplified by Pt, are known to play a significant role in the magnetization behaviour of thin-film ferromagnets by three distinct mechanisms that can each contribute to the reversal process. These include modifying the local magnetization state via an interfacial Dzyaloshinskii-Moriya interaction (IDMI), enhancement of the damping, via d-d hybridisation and spin-pumping across the interface, and the mediation of the magnetization switching, with the flow of current through a system, via the spin-Hall effect...
July 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28675034/electropolymerized-pyrrole-based-conductive-polymeric-ionic-liquids-and-their-application-for-solid-phase-microextraction
#20
Amila M Devasurendra, Cheng Zhang, Joshua A Young, L M Viranga Tillekeratne, Jared L Anderson, Jon R Kirchhoff
Pyrrole was covalently bonded to 1-methyl and 1-benzylimidazolium ionic liquids (ILs) via an N-substituted alkyl linkage to prepare electropolymerizable IL monomers with excellent thermal stability. The methylimidazolium IL, [pyrrole-C6MIm](+), was then electropolymerized on macro- and microelectrode materials to form conductive polymeric IL (CPIL)-modified surfaces. Electrochemical characterization of a 1.6 mm diameter Pt disk electrode modified with poly[pyrrole-C6MIm](+) demonstrated a selective uptake for an anionic redox probe while rejecting a cationic redox probe...
July 17, 2017: ACS Applied Materials & Interfaces
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