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Relative wall thickness

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https://www.readbyqxmd.com/read/28528661/right-sided-cardiac-dysfunction-in-heart-failure-with-preserved-ejection-fraction-and-worsening-renal-function
#1
Monica Mukherjee, Kavita Sharma, Jose A Madrazo, Ryan J Tedford, Stuart D Russell, Allison G Hays
In urban populations, worsening renal function (WRF) is well established in patients hospitalized with acute decompensated heart failure with preserved ejection fraction (HFpEF). However, the mechanisms for development of WRF in the setting of acute HF in HFpEF are unclear. In the present study, we sought to characterize conventional echocardiographic measures of right ventricular (RV) chamber size and function to determine whether RV dysfunction and/or adverse RV remodeling is related to WRF in patients with HFpEF...
April 27, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28521359/quantitative-comparison-of-the-intraoperative-utility-of-indocyanine-green-and-fluorescein-videoangiographies-in-cerebrovascular-surgery
#2
Fumihiro Matano, Takayuki Mizunari, Yasuo Murai, Asami Kubota, Yu Fujiki, Shiro Kobayashi, Akio Morita
BACKGROUND: A quantitative analysis comparing indocyanine green videoangiography (ICG-VAG) and fluorescein videoangiography (FL-VAG) in cerebrovascular surgery has not been reported so far. OBJECTIVE: To clear the differences of characteristics of ICG-VAG and FL-VAG by quantitative assessment. METHODS: We prospectively analyzed results from 23 patients (3 males; mean age at surgery: 60.9 years, range: 14-75 years) at our hospital from August 2014 to July 2015...
June 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28511861/speckle-tracking-layer-specific-analysis-of-myocardial-deformation-and-evaluation-of-scar-transmurality-in-chronic-ischemic-heart-disease
#3
Michela Tarascio, Laura Anna Leo, Catherine Klersy, Romina Murzilli, Tiziano Moccetti, Francesco Fulvio Faletra
BACKGROUND: Identification of the extent of scar transmurality in chronic ischemic heart disease is important because it correlates with viability. The aim of this retrospective study was to evaluate whether layer-specific two-dimensional speckle-tracking echocardiography allows distinction of scar presence and transmurality. METHODS: A total of 70 subjects, 49 with chronic ischemic cardiomyopathy and 21 healthy subjects, underwent two-dimensional speckle-tracking echocardiography and late gadolinium-enhanced cardiac magnetic resonance...
May 13, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28503401/bio-inspired-micro-to-nanoporous-polymers-with-tunable-stiffness
#4
Julia Syurik, Ruth Schwaiger, Prerna Sudera, Stephan Weyand, Siegbert Johnsen, Gabriele Wiegand, Hendrik Hölscher
Background: Inspired by structural hierarchies and the related excellent mechanical properties of biological materials, we created a smoothly graded micro- to nanoporous structure from a thermoplastic polymer. Results: The viscoelastic properties for the different pore sizes were investigated in the glassy regime by dynamic flat-punch indentation. Interestingly, the storage modulus was observed to increase with increasing pore-area fraction. Conclusion: This outcome appears counterintuitive at first sight, but can be rationalized by an increase of the pore wall thickness as determined by our quantitative analysis of the pore structure...
2017: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/28499613/effects-of-bisphenol-a-on-incidence-and-severity-of-cardiac-lesions-in-the-nctr-sprague-dawley-rat-a-clarity-bpa-study
#5
Robin Gear, Jessica A Kendziorski, Scott M Belcher
The goal of this study was to determine whether bisphenol A (BPA) had adverse effects indicative of cardiac toxicity. As part of the "Consortium Linking Academic and Regulatory Insights on BPA Toxicity" (CLARITY-BPA), study dams and offspring were exposed by daily gavage to five doses of BPA ranging from 2.5 to 25000μg/kg/day, 0.05 or 0.5μg/kg/day 17α-ethinyl-estradiol (EE) or 0.3% carboxymethylcellulose vehicle. Exposure-related effects were analyzed in isolated hearts by quantitative morphometry and histopathology...
May 9, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28499215/numerical-study-on-the-air-conditioning-characteristics-of-the-human-nasal-cavity
#6
Da-Woon Kim, Seung-Kyu Chung, Yang Na
The air-conditioning characteristics of the human nasal cavity were investigated using computational fluid dynamics. The wall layer was modeled as a heat conducting layer consisting of water with constant thickness placed on top of epithelial cells. By assuming constant tissue temperature, prescribed to be 36 (°)C, which is close to the alveolar condition, the proposed wall model yielded a spatially varying surface temperature distribution that is in reasonable agreement with the measurement studies in the literature...
April 30, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28499044/determinants-of-decline-of-renal-function-in-treated-hypertensive-patients-the-campania-salute-network
#7
Costantino Mancusi, Raffaele Izzo, Giovanni de Simone, Maria Viviana Carlino, Grazia Canciello, Eugenio Stabile, Nicola de Luca, Bruno Trimarco, Maria Angela Losi
Background.: Hypertension is a leading cause of chronic kidney disease (CKD) and a decrease in glomerular filtration rate (GFR) is associated with a higher prevalence of hypertension and an increased proportion of suboptimal blood pressure (BP) control. Methods.: To investigate characteristics associated with GFR decline, we selected 4539 hypertensive patients from the Campania Salute Network (mean age 53 ± 11 years) with at least 3 years of follow-up (FU) and no more than Stage III CKD...
May 12, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28497960/using-dynamic-covalent-chemistry-to-drive-morphological-transitions-controlled-release-of-encapsulated-nanoparticles-from-block-copolymer-vesicles
#8
Renhua Deng, Matthew J Derry, Charlotte J Mable, Yin Ning, Steven P Armes
Dynamic covalent chemistry is exploited to drive morphological order-order transitions to achieve the controlled release of a model payload (e.g., silica nanoparticles) encapsulated within block copolymer vesicles. More specifically, poly(glycerol monomethacrylate)-poly(2-hydroxypropyl methacrylate) (PGMA-PHPMA) diblock copolymer vesicles were prepared via aqueous polymerization-induced self-assembly in either the presence or absence of silica nanoparticles. Addition of 3-aminophenylboronic acid (APBA) to such vesicles results in specific binding of this reagent to some of the pendent cis-diol groups on the hydrophilic PGMA chains to form phenylboronate ester bonds in mildly alkaline aqueous solution (pH ∼ 10)...
May 23, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28494095/comparison-of-192-ir-169-yb-and-60-co-high-dose-rate-brachytherapy-sources-for-skin-cancer-treatment
#9
Habib Safigholi, Ali S Meigooni, William Y Song
PURPOSE: To evaluate the possibility of utilizing the high-dose rate (HDR) (169) Yb and (60) Co sources, in addition to (192) Ir, for the treatment of skin malignancies with conical applicators. METHODS: Monte Carlo (MC) simulations were used to benchmark the dosimetric parameters of single (169) Yb (4140), (60) Co (Co0.A86), and (192) Ir (mHDR-V2) brachytherapy sources in a water phantom and compared their results against published data. A standard conical tungsten alloy Leipzig-style applicator (Stand...
May 11, 2017: Medical Physics
https://www.readbyqxmd.com/read/28487704/a-combined-comparative-transcriptomic-metabolomic-and-anatomical-analyses-of-two-key-domestication-traits-pod-dehiscence-and-seed-dormancy-in-pea-pisum-sp
#10
Iveta Hradilová, Oldřich Trněný, Markéta Válková, Monika Cechová, Anna Janská, Lenka Prokešová, Khan Aamir, Nicolas Krezdorn, Björn Rotter, Peter Winter, Rajeev K Varshney, Aleš Soukup, Petr Bednář, Pavel Hanáček, Petr Smýkal
The origin of the agriculture was one of the turning points in human history, and a central part of this was the evolution of new plant forms, domesticated crops. Seed dispersal and germination are two key traits which have been selected to facilitate cultivation and harvesting of crops. The objective of this study was to analyze anatomical structure of seed coat and pod, identify metabolic compounds associated with water-impermeable seed coat and differentially expressed genes involved in pea seed dormancy and pod dehiscence...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28487243/towards-rebuilding-vaginal-support-utilizing-an-extracellular-matrix-bioscaffold
#11
Rui Liang, Katrina Knight, Deanna Easley, Stacy Palcsey, Steven Abramowitch, Pamela A Moalli
As an alternative to polypropylene mesh, we explored an extracellular matrix (ECM) bioscaffold derived from urinary bladder matrix (MatriStem™) in the repair of vaginal prolapse. We aimed to restore disrupted vaginal support simulating application via transvaginal and transabdominal approaches in a macaque model focusing on the impact on vaginal structure, function, and the host immune response. In 16 macaques, after laparotomy, the uterosacral ligaments and paravaginal attachments to pelvic side wall were completely transected (IACUC# 13081928)...
May 6, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28484616/failure-mechanism-of-hollow-tree-trunks-due-to-cross-sectional-flattening
#12
Yan-San Huang, Fu-Lan Hsu, Chin-Mei Lee, Jia-Yang Juang
Failure of hollow trees in urban areas is a worldwide concern, and it can be caused by different mechanisms, i.e. bending stresses or flattening-related failures. Here we derive a new analytical expression for predicting the bending moment for tangential cracking, and compare the breaking moment of various failure modes, including Brazier buckling, tangential cracking, shear failure and conventional bending failure, as a function of t/R ratio, where t and R are the trunk wall thickness and trunk radius, respectively, of a hollow tree...
April 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28482562/bimodal-morphological-analyses-of-native-and-engineered-tissues
#13
Sasan Jalili-Firoozinezhad, Ivan Martin, Arnaud Scherberich
Assessing the morphological features of native and engineered tissues is pivotal to evaluate their degree of development and to identify possible structure-function relationships. Conventional histological or immunohistochemical imaging of stained sections provides limited information about their architecture. Scanning electron microscopy (SEM) yields sub-micrometric resolution images of tissues, but typically cannot be associated with the morphological structures identified by histology. The aim of this study was to establish a technique based on SEM analysis of sections of paraffin-embedded tissues prepared for histological processing (Histo-SEM) for the assessment of morpho-architectural properties of native and engineered tissues...
July 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28477371/quantitative-ionization-chamber-alignment-to-a-water-surface-performance-of-multiple-chambers
#14
James D Ververs, Malcolm R McEwen, Jeffrey V Siebers
PURPOSE: To experimentally examine the reliability of the gradient chamber alignment point (gCAP) determination method for accurately identifying water surface location with a range of ionization chambers (ICs). METHOD & MATERIALS: Twelve cylindrical ICs were scanned from depth through a water surface into air using a customized high-accuracy scanning system which allows for accurate alignment of the IC with respect to the true water surface. Thirteen other cylindrical ICs and five parallel-plate ICs were scanned using a standard commercially available scanning system...
May 5, 2017: Medical Physics
https://www.readbyqxmd.com/read/28477235/down-regulation-of-the-two-component-system-and-cell-wall-biosynthesis-related-genes-was-associated-with-the-reversion-to-daptomycin-susceptibility-in-daptomycin-non-susceptible-methicillin-resistant-staphylococcus-aureus
#15
Y Iwata, K Satou, H Tsuzuku, K Furuichi, Y Senda, Y Sakai-Takemori, T Wada, S Fujita, T Miyake, H Yasuda, N Sakai, S Kitajima, T Toyama, Y Shinozaki, A Sagara, T Miyagawa, A Hara, M Shimizu, Y Kamikawa, S Kaneko, T Wada
Daptomycin (DAP) is widely used in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infection. The emergence of DAP non-susceptible MRSA strains during therapy is a major concern in clinical settings. Recent studies revealed that MRSA spontaneously reverts to a subsequent methicillin-susceptible S. aureus (MSSA) strain. However, it is not clear whether DAP non-susceptible MRSA has the ability to revert to a susceptible strain. We obtained an MRSA strain pair, DAP non-susceptible strain and subsequent DAP susceptible strain, from a patient...
May 5, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28469098/study-of-enhanced-depth-imaging-optical-coherence-tomography-in-cerebral-autosomal-dominant-arteriopathy-with-subcortical-infarcts-and-leukoencephalopathy
#16
Xiao-Jing Fang, Meng Yu, Yuan Wu, Zi-Hao Zhang, Wei-Wei Wang, Zhao-Xia Wang, Yun Yuan
BACKGROUND: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary small artery disease caused by NOTCH3 gene mutation. We performed enhanced depth imaging optical coherence tomography (EDI-OCT) to evaluate the retinal vessel changes in CADASIL patients and assessed their consonance with brain magnetic resonance imaging (MRI) findings. METHODS: Of 27 genetically confirmed patients and an equal number of controls were recruited at the Peking University First Hospital from January 2015 to August 2016...
May 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28466485/histological-characteristics-of-the-tracheobronchial-tree-of-the-least-shrew-cryptotis-parva
#17
F Arodaki, W Khamas, N Darmani, M Al-Tikriti
The least shrew (Cryptotis parva) is a small vomit-competent insectivorous species which has recently been introduced as an emesis animal model in the laboratory. In this study, the respiratory system of the least shrew was examined and compared with the well-established larger species routinely used in the laboratory. Five least shrews (4-5 g body weight, 45-60 days old) were used. Standard histological procedures were followed for light microscopic examination. The lining epithelium of the trachea was found to be pseudostratified ciliated columnar (PSCC)...
May 3, 2017: Anatomia, Histologia, Embryologia
https://www.readbyqxmd.com/read/28466074/cystitis-cystica-as-a-large-solitary-bladder-cyst
#18
Stephanie Potts, John Calleary
Background: In this case we describe the rare and not previously documented presentation of cystitis cystica as a large solitary cystic lesion within the bladder wall. Case Presentation: We present a case of a 46-year-old Russian male with a history of lower urinary tract symptoms and suprapubic pain. CT urogram showed a 5.8 cm filling defect/cystic mass related to the base of the bladder and prostate with 8 mm thick wall. The patient underwent cystoscopy and contrast study of bladder lesion with urethral dilatation and transurethral deroofing of bladder wall cyst under general anesthesia...
2017: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/28461289/associations-in-asthma-between-quantitative-computed-tomography-and%C3%A2-bronchial-biopsy-derived-airway-remodelling
#19
Rachid Berair, Ruth Hartley, Vijay Mistry, Ajay Sheshadri, Sumit Gupta, Amisha Singapuri, Sherif Gonem, Richard P Marshall, Ana R Sousa, Aarti Shikotra, Richard Kay, Andrew Wardlaw, Peter Bradding, Salman Siddiqui, Mario Castro, Christopher E Brightling
Airway remodelling in asthma remains poorly understood. This study aimed to determine the association of airway remodelling measured on bronchial biopsies with 1) lung function impairment and 2) thoracic quantitative computed tomography (QCT)-derived morphometry and densitometry measures of proximal airway remodelling and air trapping.Subjects were recruited from a single centre. Bronchial biopsy remodelling features that were the strongest predictors of lung function impairment and QCT-derived proximal airway morphometry and air trapping markers were determined by stepwise multiple regression...
May 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28459993/the-association-between-alcohol-consumption-and-left-ventricular-diastolic-function-and-geometry-change-in-general-korean-population
#20
Sung Keun Park, Kanghee Moon, Jae-Hong Ryoo, Chang-Mo Oh, Joong-Myung Choi, Jeong Gyu Kang, Ju Youn Chung, Ju Young Jung
Aims: The adverse effect of heavy alcohol intake on cardiovascular disease is well established. However, there is only limited information about the risk of subclinical left ventricular (LV) abnormality according to alcohol consumption. Thus, this study was to investigate the association between alcohol consumption and LV functional and structural abnormality. Methods and results: Study participants were 49 714 Korean adults received echocardiogram as an item of health check-up program...
April 27, 2017: European Heart Journal Cardiovascular Imaging
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