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https://www.readbyqxmd.com/read/28645156/rem-sleep-behavior-disorder-and-cognitive-impairment-in-parkinson-s-disease
#1
Natalia Jozwiak, Ronald B Postuma, Jacques Montplaisir, Véronique Latreille, Michel Panisset, Sylvain Chouinard, Pierre-Alexandre Bourgouin, Jean-François Gagnon
Study Objectives: REM sleep behavior disorder (RBD) is a parasomnia affecting 33 to 46% of patients with Parkinson's disease (PD). The existence of a unique and specific impaired cognitive profile in PD patients with RBD is still controversial. We extensively assessed cognitive functions to identify whether RBD is associated with more severe cognitive deficits in nondemented patients with PD. Methods: One hundred and sixty-two participants, including 53 PD patients with RBD, 40 PD patients without RBD, and 69 healthy subjects, underwent polysomnography, a neurological assessment, and an extensive neuropsychological exam to assess attention, executive functions, episodic learning and memory, visuospatial abilities, and language...
June 22, 2017: Sleep
https://www.readbyqxmd.com/read/28641164/protective-effects-of-flavonoids-against-alzheimer-s-disease-related-neural-dysfunctions
#2
REVIEW
Mahsa Bakhtiari, Yunes Panahi, Javad Ameli, Behrad Darvishi
Senile ages of human life is mostly associated with developmental of several neurological complicated conditions including decreased cognition and reasoning, increased memory loss and impaired language performance. Alzheimer's disease (AD) is the most prevalent neural disorder associated with dementia, consisting of about 70% of dementia reported cases. Failure of currently approved chemical anti-AD therapeutic agents has once again brought up the idea of administering naturally occurring compounds as effective alternative and/or complementary regimens in AD treatment...
June 19, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28639319/diet-physical-activity-and-behavioural-interventions-for-the-treatment-of-overweight-or-obese-children-from-the-age-of-6-to-11-years
#3
REVIEW
Emma Mead, Tamara Brown, Karen Rees, Liane B Azevedo, Victoria Whittaker, Dan Jones, Joan Olajide, Giulia M Mainardi, Eva Corpeleijn, Claire O'Malley, Elizabeth Beardsmore, Lena Al-Khudairy, Louise Baur, Maria-Inti Metzendorf, Alessandro Demaio, Louisa J Ells
BACKGROUND: Child and adolescent overweight and obesity has increased globally, and can be associated with significant short- and long-term health consequences. This is an update of a Cochrane review published first in 2003, and updated previously in 2009. However, the update has now been split into six reviews addressing different childhood obesity treatments at different ages. OBJECTIVES: To assess the effects of diet, physical activity and behavioural interventions (behaviour-changing interventions) for the treatment of overweight or obese children aged 6 to 11 years...
June 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28635503/practical-guidelines-to-minimise-language-and-cognitive-confounds-in-the-diagnosis-of-capd-a-brief-tutorial
#4
Gail D Chermak, Doris-Eva Bamiou, Vasiliki Vivian Iliadou, Frank E Musiek
OBJECTIVE: To provide audiologists with strategies to minimise confounding cognitive and language processing variables and accurately diagnose central auditory processing disorder (CAPD). DESIGN: Tutorial. STUDY SAMPLE: None. RESULTS: Strategies are reviewed to minimise confounding cognitive and language processing variables and accurately diagnose CAPD. CONCLUSIONS: Differential diagnosis is exceedingly important and can be quite challenging...
February 28, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28635323/preserving-employee-privacy-in-wellness
#5
Paul E Terry
The proposed "Preserving Employee Wellness Programs Act" states that the collection of information about the manifested disease or disorder of a family member shall not be considered an unlawful acquisition of genetic information. The bill recognizes employee privacy protections that are already in place and includes specific language relating to nondiscrimination based on illness. Why did legislation expressly intending to "preserve wellness programs" generate such antipathy about wellness among journalists? This article argues that those who are committed to preserving employee wellness must be equally committed to preserving employee privacy...
July 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/28632303/audition-specific-temporal-processing-deficits-associated-with-language-function-in-children-with-autism-spectrum-disorder
#6
Jennifer H Foss-Feig, Kimberly B Schauder, Alexandra P Key, Mark T Wallace, Wendy L Stone
Sensory processing alterations are highly prevalent in autism spectrum disorder (ASD). Neurobiologically-based theories of ASD propose that abnormalities in the processing of temporal aspects of sensory input could underlie core symptoms of ASD. For example, rapid auditory temporal processing is critical for speech perception, and language difficulties are central to the social communication deficits defining the disorder. This study assessed visual and auditory temporal processing abilities and tested their relation to core ASD symptoms...
June 20, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28625346/the-role-of-the-motor-system-in-action-naming-in-patients-with-neurodegenerative-extrapyramidal-syndromes
#7
REVIEW
Maria Cotelli, Rosa Manenti, Michela Brambilla, Barbara Borroni
Previous studies of patients with brain damage have suggested a close relationship between aphasia and movement disorders. Neurodegenerative extrapyramidal syndromes associated with cognitive impairment provide an interesting model for studying the neural substrates of cognitive and motor symptoms. In this review, we focused on studies investigating language production abilities in patients with Parkinson's disease (PD), Corticobasal Syndrome (CBS) and Progressive Supranuclear Palsy (PSP). According to some reports, these patients exhibit a reduction in performance in both action and object naming or verb production compared to healthy individuals...
May 26, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28624817/exploring-the-clinical-practice-of-speech-and-language-therapists-with-adults-with-dementia-a-cross-sectional-survey-in-portugal
#8
Jossie Nóbrega, Marisa Lousada, Daniela Figueiredo
BACKGROUND/AIMS: Adults with acquired communication and swallowing disorders secondary to dementia can benefit from speech and language therapy services. However, there is limited information on the role of speech and language therapists (SLTs) in the treatment of individuals with dementia. The aim of this study was to explore the clinical practice of SLTs with adults with dementia. METHODS: A cross-sectional survey of SLTs was conducted in Portugal using a web-based questionnaire designed specifically for the purpose of this study...
June 17, 2017: Folia Phoniatrica et Logopaedica
https://www.readbyqxmd.com/read/28621218/measuring-disability-in-patients-with-cervical-dystonia-according-to-the-international-classification-of-functioning-disability-and-health
#9
Joke De Pauw, Kevin van der Velden, Reen Cox, Steven Truijen, Patrick Cras, Rudy Mercelis, Willem De Hertogh
Cervical Dystonia (CD) is a rare movement disorder characterized by an abnormal head position. This cross-sectional study describes the health status and severity of disability using an internationally agreed language by applying the International Classification of Functioning, Disability and Health (ICF). Two disease-specific rating scales were administered to 30 patients with CD. By linking the individual answers to the ICF model, the frequency and severity of reported impairments and restrictions were estimated using a count-based method...
July 2017: OTJR: Occupation, Participation and Health
https://www.readbyqxmd.com/read/28613384/communication-skills-training-for-mental-health-professionals-working-with-people-with-severe-mental-illness
#10
REVIEW
Alexia Papageorgiou, Yoon K Loke, Michelle Fromage
BACKGROUND: Research evidence suggests that both mental health professionals and people with severe mental health illness such as schizophrenia or schizoaffective disorder find it difficult to communicate with each other effectively about symptoms, treatments and their side effects so that they reach a shared understanding about diagnosis, prognosis and treatment. Effective use of communication skills in mental health interactions could be associated with increased patient satisfaction and adherence to treatment...
June 13, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28611885/american-association-for-emergency-psychiatry-task-force-on-medical-clearance-of-adult-psychiatric-patients-part-ii-controversies-over-medical-assessment-and-consensus-recommendations
#11
REVIEW
Michael P Wilson, Kimberly Nordstrom, Eric L Anderson, Anthony T Ng, Leslie S Zun, Jennifer M Peltzer-Jones, Michael H Allen
INTRODUCTION: The emergency medical evaluation of psychiatric patients presenting to United States emergency departments (ED), usually termed "medical clearance," often varies between EDs. A task force of the American Association for Emergency Psychiatry (AAEP), consisting of physicians from emergency medicine, physicians from psychiatry and a psychologist, was convened to form consensus recommendations for the medical evaluation of psychiatric patients presenting to U.S.EDs. METHODS: The task force reviewed existing literature on the topic of medical evaluation of psychiatric patients in the ED and then combined this with expert consensus...
June 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28608733/differential-profiles-of-four-groups-of-children-referred-to-an-autism-diagnostic-service-in-belgium-autism-specific-hallmarks
#12
Sophie Carlier, Nastasia Kurzeja, Lesley Ducenne, Nathalie Pauwen, Christophe Leys, Véronique Delvenne
OBJECTIVE: This article aims at exploring distinctive hallmarks of autistic disorders compared to other groups presenting mimicking and/or overlapping conditions. METHOD: The exploratory study involved 196 children with autism, intellectual disability, language impairment and psycho-affective disorders previously referred to an autism diagnostic service. The autism discriminative tool (ADT), a behavioural checklist, was used to compile and analyse the children's profiles based on the clinical information gathered during diagnostic assessments...
January 1, 2017: Journal of Intellectual Disabilities: JOID
https://www.readbyqxmd.com/read/28606869/predicting-mental-conditions-based-on-history-of-present-illness-in-psychiatric-notes-with-deep-neural-networks
#13
Tung Tran, Ramakanth Kavuluru
BACKGROUND: Applications of natural language processing to mental health notes are not common given the sensitive nature of the associated narratives. The CEGS N-GRID 2016 Shared Task in Clinical Natural Language Processing (NLP) changed this scenario by providing the first set of neuropsychiatric notes to participants. This study summarizes our efforts and results in proposing a novel data use case for this dataset as part of the third track in this shared task. OBJECTIVE: We explore the feasibility and effectiveness of predicting a set of common mental conditions a patient has based on the short textual description of patient's history of present illness typically occurring in the beginning of a psychiatric initial evaluation note...
June 9, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28602906/counting-trees-in-random-forests-predicting-symptom-severity-in-psychiatric-intake-reports
#14
Elyne Scheurwegs, Madhumita Sushil, Stéphan Tulkens, Walter Daelemans, Kim Luyckx
The CEGS N-GRID 2016 Shared Task (Filannino, Stubbs, Uzuner (2017)) in Clinical Natural Language Processing introduces the assignment of a severity score to a psychiatric symptom, based on a psychiatric intake report. We present a method that employs the inherent interview-like structure of the report to extract relevant information from the report and generate a representation. The representation consists of a restricted set of psychiatric concepts (and the context they occur in), identified using medical concepts defined in UMLS that are directly related to the psychiatric diagnoses present in the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) ontology...
June 7, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28597028/-aphasia-a%C3%A2-neuronal-network-disorder
#15
REVIEW
A Stockert, D Saur
Language processing requires the coordinated interaction of local and distant neural populations within distributed networks of the temporal, frontal and parietal brain regions. Poststroke aphasia is the consequence of both local as well as remote dysfunction within language-specific and domain-general networks. Language recovery, in turn, rests on reorganization processes within these networks. These comprise the resolution of an acute network failure (i. e. diaschisis), the subacute activation of right hemisphere homologous regions and the gradual reintegration of left hemisphere remote and perilesional areas...
June 8, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28592562/functional-neuroimaging-of-high-risk-6-month-old-infants-predicts-a-diagnosis-of-autism-at-24-months-of-age
#16
Robert W Emerson, Chloe Adams, Tomoyuki Nishino, Heather Cody Hazlett, Jason J Wolff, Lonnie Zwaigenbaum, John N Constantino, Mark D Shen, Meghan R Swanson, Jed T Elison, Sridhar Kandala, Annette M Estes, Kelly N Botteron, Louis Collins, Stephen R Dager, Alan C Evans, Guido Gerig, Hongbin Gu, Robert C McKinstry, Sarah Paterson, Robert T Schultz, Martin Styner, Bradley L Schlaggar, John R Pruett, Joseph Piven
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by social deficits and repetitive behaviors that typically emerge by 24 months of age. To develop effective early interventions that can potentially ameliorate the defining deficits of ASD and improve long-term outcomes, early detection is essential. Using prospective neuroimaging of 59 6-month-old infants with a high familial risk for ASD, we show that functional connectivity magnetic resonance imaging correctly identified which individual children would receive a research clinical best-estimate diagnosis of ASD at 24 months of age...
June 7, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28591751/prognostic-accuracy-of-mild-cognitive-impairment-subtypes-at-different-cut-off-levels
#17
Mattias Göthlin, Marie Eckerström, Sindre Rolstad, Anders Wallin, Arto Nordlund
BACKGROUND/AIMS: The prognostic accuracy of mild cognitive impairment (MCI) in clinical settings is debated, variable across criteria, cut-offs, subtypes, and follow-up time. We aimed to estimate the prognostic accuracy of MCI and the MCI subtypes for dementia using three different cut-off levels. METHODS: Memory clinic patients were followed for 2 (n = 317, age 63.7 ± 7.8) and 4-6 (n = 168, age 62.6 ± 7.4) years. We used 2.0, 1.5, and 1.0 standard deviations (SD) below the mean of normal controls (n = 120, age 64...
2017: Dementia and Geriatric Cognitive Disorders
https://www.readbyqxmd.com/read/28579383/clinical-and-biological-phenotypes-of-frontotemporal-dementia-perspectives-for-disease-modifying-therapies
#18
S Gazzina, M A Manes, A Padovani, B Borroni
Frontotemporal Dementia (FTD) is a progressive neurodegenerative condition which encompasses a group of clinically, neuropathologically and genetically heterogeneous disorders characterized by selective involvement of the frontal and temporal lobes. FTD is characterized by changes in behaviour and personality, frontal executive deficits and language dysfunction. Different phenotypes have been defined on the basis of presenting clinical symptoms, behavioural variants of FTD (bvFTD) and primary progressive aphasia (PPA), which includes nonfluent/agrammatic variant PPA (avPPA) and semantic variant PPA (svPPA)...
June 1, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28577444/auditory-processing-deficits-are-sometimes-necessary-and-sometimes-sufficient-for-language-difficulties-in-children-evidence-from-mild-to-moderate-sensorineural-hearing-loss
#19
Lorna F Halliday, Outi Tuomainen, Stuart Rosen
There is a general consensus that many children and adults with dyslexia and/or specific language impairment display deficits in auditory processing. However, how these deficits are related to developmental disorders of language is uncertain, and at least four categories of model have been proposed: single distal cause models, risk factor models, association models, and consequence models. This study used children with mild to moderate sensorineural hearing loss (MMHL) to investigate the link between auditory processing deficits and language disorders...
May 31, 2017: Cognition
https://www.readbyqxmd.com/read/28573387/the-impact-of-change-of-renal-replacement-therapy-modality-on-sleep-quality-in-patients-with-end-stage-renal-disease-a-systematic-review-and-meta-analysis
#20
REVIEW
C Kennedy, S A Ryan, T Kane, R W Costello, P J Conlon
BACKGROUND: Sleep disorders are common and multi-factorial in patients with advanced chronic kidney disease and end-stage renal disease (ESRD). Sleep disorders and disturbance have a negative impact on wellbeing and quality of life. OBJECTIVE: To assess the impact of a change in renal replacement therapy (RRT) modality on sleep quality and sleep disturbance in patients with ESRD. DATA SOURCES: Multiple electronic databases were searched without publication type/period restrictions...
June 1, 2017: Journal of Nephrology
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