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Andreas Gösele-Koppenburg
Chronic compartment syndromes are a rare, but frequently overlooked cause of pain in the locomotor system. Their aetiology is still not fully elucidated. There is an imbalance of muscle volume and space in the compartment. Thickening of the fascia and decreased elasticity lead to a pathological increase in pressure in the compartment under load. Chronic compartment syndromes are found in the foot, lower leg, thigh, forearm, hand, and even the spine. Bilateral compartment syndromes are very common (80 %). The main symptoms are pain in the compartment under physical activity...
March 2018: Sportverletzung Sportschaden: Organ der Gesellschaft Für Orthopädisch-Traumatologische Sportmedizin
É Duvelle, K J Jeffery
How does the brain represent the location of others? Recordings in rats and bats show that, along with representing self-location in an environment, some hippocampal neurons are modulated by the position of another individual.
March 19, 2018: Current Biology: CB
Stefano Battaglia, Sebastian Keller, Stefan Knecht
We present an implementation of the relativistic quantum-chemical density matrix renormalization group (DMRG) approach based on a matrix-product formalism. Our approach allows us to optimize matrix product state (MPS) wave functions including a variational description of scalar-relativistic effects and spin-orbit coupling from which we can calculate, for example, first-order electric and magnetic properties in a relativistic framework. While complementing our pilot implementation (S. Knecht et al., J. Chem...
March 20, 2018: Journal of Chemical Theory and Computation
Kimberly S Chiew, Jordan Hashemi, Lee K Gans, Laura Lerebours, Nathaniel J Clement, Mai-Anh T Vu, Guillermo Sapiro, Nicole E Heller, R Alison Adcock
Volitional exploration and learning are key to adaptive behavior, yet their characterization remains a complex problem for cognitive science. Exploration has been posited as a mechanism by which motivation promotes memory, but this relationship is not well-understood, in part because novel stimuli that motivate exploration also reliably elicit changes in neuromodulatory brain systems that directly alter memory formation, via effects on neural plasticity. To deconfound interrelationships between motivation, exploration, and memory formation we manipulated motivational state prior to entering a spatial context, measured exploratory responses to the context and novel stimuli within it, and then examined motivation and exploration as predictors of memory outcomes...
2018: PloS One
Monther A Khanfar, Areej M Jaber, Murad A AlDamen, Raed A Al-Qawasmeh
A copper complex with square planar geometry, [(L)CuBr₂] ( 1 ), (L = N' -(furan-2-ylmethylene)adamantne-1-carbohydrazide) has been synthesized and characterized by Fourier transfer infrared (FTIR) spectroscopy, elemental analysis, mass spectrometry, and single crystal X-ray diffraction. The crystal of 1 is solved as monoclinic, space group P2₁/m with unit cell parameters: a = 10.8030(8), b = 6.6115(8), c = 12.1264(12) Å, β = 101.124(8)°, V = 849.84(15) ų, Z = 2, and R₁ = 0.0751 with wR₂ = 0.1581 (I > 2 σ)...
March 20, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Katherine A Prentice, Erica K Argyropoulos
The objective of this article is to describe the recent space and furniture utilization study conducted through direct observation at the small, academic-centered Schusterman Library. Student workers from the library's reference desk monitored two semesters of use and went on to observe a third semester after electrical power upgrades were installed. Extensive use details were collected about where library patrons sat during which parts of the day, and certain areas of the library were ultimately identified as much more active than others...
April 2018: Medical Reference Services Quarterly
Jonathan Lichtenberger, Kathryn M Meurs, Etienne Côté
Cardiac arrhythmias often are transient and might not be detected using conventional electrocardiographic (ECG) techniques. The adhesive patch monitor (APM) is a single-lead, lightweight, up to 14-day continuous ambulatory ECG monitor. This study aimed to prospectively assess its usability in four boxer dogs considered either to be healthy or to have arrhythmogenic right ventricular cardiomyopathy. Optimal recording was obtained by placing the APM on the left side of the animal's thorax, at the fifth intercostal space, slightly dorsal to the costochondral junction, and oriented either vertically or parallel to the long axis of the heart...
March 20, 2018: Journal of the American Animal Hospital Association
Hui Hu, Boyi Zhang, Adam Luxon, Thais Scott, Baoshan Wang, Carol A Parish
The 9,10-didehydroanthracene is an aromatic diradical produced by the Bergman cyclization of a benzannulated 10-membered enediyne. It is a 1,4 diradical, similar to para-benzyne. Here we study the spin state occupancy of the ground state of 9,10-didehydroanthracene by employing multireference methods (MR-CISD and MR-AQCC) with different basis sets (cc-pVDZ and cc-pVTZ) and active space sizes (CAS (2,2) through CAS (8,8)). At the CAS (8,8) MR-AQCC/cc-pVDZ level of theory, we find a two-configurational singlet ground state with an adiabatic EST of 6...
March 20, 2018: Journal of Physical Chemistry. A
Vincent A Spata, Emily A Carter
Nanoparticles synthesized from plasmonic metals can absorb low-energy light, producing an oscillation/excitation of their valence electron density that can be utilized in chemical conversions. For example, heterogeneous photocatalysis can be achieved within heterometallic antenna-reactor complexes (HMARCs), by coupling a reactive center at which a chemical reaction occurs to a plasmonic nanoparticle that acts as a light-absorbing antenna. For example, HMARCs composed of aluminum antennae and palladium (Pd) reactive centers have been demonstrated recently to catalyze selective hydrogenation of acetylene to ethylene...
March 20, 2018: ACS Nano
Joshua M Peterson, Carolyn Chlebek, Ashley M Clough, Alexandra K Wells, Kathleen E Batzinger, John M Houston, Katerina Kradinova, Joseph C Glennon, Darryl J DiRisio, Eric H Ledet
STUDY DESIGN: Real time in vivo measurement of forces in the cervical spine of goats following anterior cervical discectomy and fusion (ACDF). OBJECTIVE: To measure interbody forces in the cervical spine during the time course of fusion following ACDF with plates of different stiffnesses. SUMMARY OF BACKGROUND DATA: Following ACDF, the biomechanics of the arthrodesis is largely dictated by the plate. The properties of the plate prescribe the extent of load-sharing through the disc space versus the extent of stress-shielding...
March 19, 2018: Spine
Gokhan Boyraz, Fatma Oz Atalay, Mehmet Coskun Salman, Alp Usubutun, Anil Erturk, Murat Gultekin, Nejat Ozgul, Kunter Yuce
OBJECTIVE: The aim of this study was to compare Mayo and Milwaukee risk stratification models for predicting lymphatic dissemination in patients with endometrial cancer (EC). METHODS: A total of 904 patients with EC underwent surgical treatment between 2004 and 2016 at Hacettepe University Hospital, and clinicopathological data of patients were retrieved from the computerized database of the Hacettepe University. Patients who did not undergo lymphadenectomy and who had nonendometrioid histology, stage-IV disease, and synchronous epithelial ovarian and EC were excluded...
March 20, 2018: International Journal of Gynecological Cancer
Rajesh Sharma, Lalit Kumar Saini, Bhagwati Prasad Bahuguna
We study the phase diagram of symmetric electron-hole bilayer at zero temperature and zero magnetic field within quantum Monte Carlo approach. Particularly, we conduct variational Monte Carlo simulation for various phases viz. paramagnetic fluid phase, ferromagnetic fluid phase, anti-ferromagnetic Wigner crystal phase, ferromagnetic Wigner crystal phase and excitonic phase to
 estimate the ground-state energy at different values of inlayer density and inter-layer spacing. The Slater-Jastrow style trial wave function, with suitable single particle orbitals appropriate for different phases, are used to construct the phase diagram in (r<sub>s</sub> , d) plane by finding relative stability of trial wave functions...
March 20, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Lee Ena, Jong Seung Lim, Ji Yeon Son, Yu Jin Park, Yong Hee Lee, Ji Yeong Kim, Seung Jun Kwack, Byung Mu Lee, Mee-Young Ahn, Hyung Sik Kim
Triclosan (TCS), a common antimicrobial ingredient, is present in many consumer products, including soaps, shampoos, and toothpaste. Owing to its widespread use, potential adverse effects on animals and humans may arise from lifetime exposure, but data on chronic prepubertal exposure of TCS are still lacking. The aim of the present study was to investigate the influence of subchronic TCS exposure (0.25, 25, 250, or 750 mg/kg) on target organ toxicity in prepubertal male rats. After daily administration of TCS to rats by oral gavage for 60 d, a significant reduction in body weight and relative weights of liver, kidneys, testes, and adrenal glands was observed in the 750-mg/kg (high dose) group...
March 20, 2018: Journal of Toxicology and Environmental Health. Part A
Tanuj Sharma, Mohammad Imran Siddiqi
Unique intrinsic properties of peptides like low toxicity, high biological activity and specificity make them attractive therapeutic agents. PDZ binding peptide inhibitors have been demonstrated for curing of Alzheimer, Parkinson, Dementia and other central nervous system ailments. In this article, we report the successful use of an integrated computational protocol to analyze the structural basis of how peptides bind to the shallow groove of the third PDZ domain (PDZ3) from the Post Synaptic Density (PSD-95) protein...
March 20, 2018: Journal of Biomolecular Structure & Dynamics
Kae Akita, Seiichiro Hasezawa, Takumi Higaki
We previously found that sucrose solution immersion treatment permitted ectopic guard cell differentiation, resulting in clustered stomatal guard cells. Using this system, we examined the effects of sucrose solution-induced stomatal clustering on guard cell cortical microtubules and the stomatal response to fusicoccin. Confocal observation revealed that the radial orientation of cortical microtubules was largely maintained in clustered guard cells. Outward movement of cortical microtubule plus-ends was also kept in the clustered guard cells...
March 20, 2018: Plant Signaling & Behavior
Kim Ngan Tran, Jong-Il Choi
PURPOSE: To study gene expression modulation in response to continuous whole-body exposure to low-dose-rate gamma radiation and improve our understanding of the mechanism of this impact at the molecular basis. MATERIALS AND METHODS: cDNA microarray method with complete pooling of samples was used to study expression changes in the transcriptome profile of livers from rats treated with prolonged low-dose-rate ionizing radiation relative to that of sham-irradiated rats...
March 20, 2018: International Journal of Radiation Biology
Paulo Cáceres Guido, Beatriz G Varela, Hernán G Bach, Ziomara Balbarrey, Marcelo L Wagner
Humans coming in contact with natural green spaces experience beneficial physical, mental, and social effects. For the primary purpose of describing plant species found in the gardens of Hospital de Pediatría "Prof. Dr. Juan P. Garrahan" (Autonomous City of Buenos Aires), a taxonomic survey was carried out between December 2013 and November 2016. A secondary objective was to review the extent of knowledge on how natural green spaces affect the health of hospitalized patients. There are 69 plant species from 47 botanical families; of these, only 8% are native...
April 1, 2018: Archivos Argentinos de Pediatría
Tsegaye Bekele, Jason Globerman, James Watson, Stephen W Hwang, Keith Hambly, Jay Koornstra, Glen Walker, Jean Bacon, Sean B Rourke
We examined social determinants of health associated with all-cause mortality among 602 people living with HIV/AIDS in Ontario, Canada. Mortality status was verified at 1-, 3-, and 5-year follow-up visits with information obtained from proxies (family members, partners, and friends), obituaries, and local AIDS memorial lists. Of the 454 people for whom mortality information was available, 53 individuals died yielding a crude mortality rate of 22.3 deaths per 1000 person-years, a rate substantially higher than the rate in the general population (6...
March 20, 2018: AIDS and Behavior
David Pitskhelauri, Elina Kudieva, Dmitrii Moshchev, Evgeny Ananev, Michail Shifrin, Gleb Danilov, Tatiana Melnikova-Pitskhelauri, Igor Kachkov, Andrey Bykanov, Alexander Sanikidze
OBJECTIVE: A pseudomeningocele and an incisional cerebrospinal fluid leak are considered frequent complications following neurosurgical operations. The rate of these complications especially increases following neurosurgical procedures on the posterior cranial fossae. According to some publications, the rate of pseudomeningoceles has been reported as high as 40%, whereas that of incisional cerebrospinal fluid leaks is up to 17%. For the purposes of reducing the risk of these complications after a midline suboccipital craniotomy, we propose suturing the arachnoid membrane of the cisterna magna...
March 20, 2018: Acta Neurochirurgica
E Nji Nde Aboringong, Alain M Dikandé
The amide-I [Formula: see text] -helix protein is a long molecular chain made up of regularly spaced peptide groups interacting via C=O bonds. According to the current theory the energy released by hydrolyzed adenosine triphosphate is carried across the protein via vibration modes, caused by C=O bond stretchings which, in the presence of anharmonic molecular vibrations, can promote nonlinear localized excitations called excitons. In this work the effects of long-range interactions between amide-I molecules on the modulational instability of small-amplitude excitons, and on characteristic parameters of soliton wavetrain-type excitons, are investigated with emphasis on long-range interactions saturating at finite intermolecular interaction ranges...
March 21, 2018: European Physical Journal. E, Soft Matter
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