keyword
MENU ▼
Read by QxMD icon Read
search

Space

keyword
https://www.readbyqxmd.com/read/29786862/experimental-fluence-modulated-proton-computed-tomography-by-pencil-beam-scanning
#1
George Dedes, Robert P Johnson, Mark Pankuch, Nick Detrich, Willemijn M A Pols, Simon Rit, Reinhard W Schulte, Katia Parodi, Guillaume Landry
PURPOSE: This experimental study is aimed at demonstrating, using a simple cylindrical water phantom, the feasibility of fluence modulated proton computed tomography (FMpCT) by pencil beam scanning (PBS) proton computed tomography (pCT). METHODS: The phase II pCT prototype of the Loma Linda U. and U. C. Santa Cruz was operated using the PBS beam line of the Northwestern Medicine Chicago Proton Center. A 20x10 grid of 1.37 cm full width half maximum pencil beams (PB) equally spaced by 1 cm was used to acquire 45 projections in step and shoot mode...
May 22, 2018: Medical Physics
https://www.readbyqxmd.com/read/29786852/evolution-of-lobar-abnormalities-of-cerebral-glucose-metabolism-in-41-children-with-drug-resistant-epilepsy
#2
Tuhina Govil-Dalela, Ajay Kumar, Michael E Behen, Harry T Chugani, Csaba Juhász
OBJECTIVE: We analyzed long-term changes of lobar glucose metabolic abnormalities in relation to clinical seizure variables and development in a large group of children with medically refractory epilepsy. METHODS: Forty-one children (25 males) with drug-resistant epilepsy had a baseline positron emission tomography (PET) scan at a median age of 4.7 years; the scans were repeated after a median of 4.3 years. Children with progressive neurological disorders or space-occupying lesion-related epilepsy and those who had undergone epilepsy surgery were excluded...
May 22, 2018: Epilepsia
https://www.readbyqxmd.com/read/29786776/a-framework-for-image-based-modeling-of-acute-myocardial-ischemia-using-intramurally-recorded-extracellular-potentials
#3
Brett M Burton, Kedar K Aras, Wilson W Good, Jess D Tate, Brian Zenger, Rob S MacLeod
The biophysical basis for electrocardiographic evaluation of myocardial ischemia stems from the notion that ischemic tissues develop, with relative uniformity, along the endocardial aspects of the heart. These injured regions of subendocardial tissue give rise to intramural currents that lead to ST segment deflections within electrocardiogram (ECG) recordings. The concept of subendocardial ischemic regions is often used in clinical practice, providing a simple and intuitive description of ischemic injury; however, such a model grossly oversimplifies the presentation of ischemic disease-inadvertently leading to errors in ECG-based diagnoses...
May 21, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29786708/platforms-for-rapid-cancer-characterization-by-ambient-mass-spectrometry-advancements-challenges-and-opportunities-for-improvement-towards-intrasurgical-use
#4
Michael Woolman, Arash Zarrine-Afsar
Ambient Mass Spectrometry (MS) analysis is widely used to characterize biological and non-biological samples. Advancements that allow rapid analysis of samples by ambient methods such as Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) and Rapid Evaporative Ionization Mass Spectrometry (REIMS) are discussed. A short, non-comprehensive overview of ambient MS is provided that only contains example applications due to space limitations. A spatially encoded mass spectrometry analysis concept to plan cancer resection is introduced...
May 22, 2018: Analyst
https://www.readbyqxmd.com/read/29786676/-the-modern-approaches-to-the-restoration-of-postural-balance-in-the-patients-suffering-from-the-consequences-of-an-acute-cerebrovascular-accident-cva
#5
S A Volovets, E Y Sergeenko, L Y Darinskaya, B A Polyaev, Y A Yashinina, M A Isaeva, I V Zhitareva, A N Lobov, T I Panova
BACKGROUND: the most frequent and severe consequences of an acute cerebrovascular accident (CVA) are locomotor and coordination disorders which significantly increase the risk of falling in a static position and when walking. The methods used for the rehabilitation of the affected patients are designed in the first place to enable the patients to acquire the skills necessary for maintaining the static balance. The modern equipment allows to carry out coordination training in the static position and also during walking...
May 21, 2018: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/29786620/the-effect-of-bottom-electrode-on-ferroelectric-tunnel-junctions-based-on-cmos-compatible-hfo2
#6
Youngin Goh, Sanghun Jeon
Ferroelectric tunnel junctions (FTJs) have attracted research interest as promising candidates for non-destructive readout non-volatile memories. Unlike conventional perovskite FTJs, hafnia FTJ offers many advantages in terms of scalability and CMOS compatibility. However, so far, hafnia FTJ has shown poor endurance and relatively low resistance ratio and these have remained the issue for real device applications. In our study, we fabricated HfZrO-based FTJ with various electrodes (TiN, Si, SiGe, Ge) and improved the memory performance of HfZrO-based FTJ by using the asymmetry of the charge screening lengths of the electrodes...
May 22, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29786614/a-novel-optimization-framework-for-vmat-with-dynamic-gantry-couch-rotation
#7
Qihui Lyu, Victoria Y Yu, Dan Ruan, Ryan Neph, Daniel O'Connor, Ke Sheng
Existing Volumetric Modulated Arc Therapy (VMAT) optimization using coplanar arcs is highly efficient but usually dosimetrically inferior to intensity modulated radiation therapy (IMRT) with optimized non-coplanar beams. To achieve both dosimetric quality and delivery efficiency, we proposed in this study, a novel integrated optimization method for non-coplanar VMAT (4πVMAT). 4πVMAT with Direct Aperture Optimization (DAO) was achieved by utilizing a least square dose fidelity objective, along with an anisotropic total variation term for regularizing the fluence smoothness, a single segment term for imposing simple apertures, and a group sparsity term for selecting beam angles...
May 22, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29786613/biophysics-of-membrane-curvature-remodeling-at-molecular-and-mesoscopic-lengthscales
#8
Natesan Ramakrishnan, Ryan P Bradley, Richard W Tourdot, Ravi Radhakrishnan
At the micron scale, where cell organelles display an amazing complexity in their shape and organization, the physical properties of a biological membrane can be better-understood using continuum models subject to thermal (stochastic) undulations. Yet, the chief orchestrators of these complex and intriguing shapes are a specialized class of membrane associating often peripheral proteins called curvature remodeling proteins (CRPs) that operate at the molecular level through specific protein-lipid interactions...
May 22, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29786608/microscopic-aspects-of-wetting-using-classical-density-functional-theory
#9
Peter Yatsyshin, Miguel A Duran-Olivencia, Serafim Kalliadasis
Wetting is a rather efficient mechanism for nucleation of a phase (typically liquid) on the interface
 between two other phases (typically solid and gas). In many experimentally
 accessible cases of wetting, the interplay between the substrate structure,
 and the fluid-fluid and fluid-substrate intermolecular interactions brings
 about an entire ``zoo" of possible fluid configurations, such as liquid
 films with a thickness of a few nanometers, liquid nanodrops and liquid
 bridges...
May 22, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29786463/hybrid-diffusion-imaging-in-mild-traumatic-brain-injury
#10
Yu-Chien Wu, Sourajit Mitra Mustafi, Jaroslaw Harezlak, Chandana Kodiweera, Laura A Flashman, Thomas McAllister
Mild traumatic brain injury (mTBI) is an important public health problem. Although conventional medical imaging techniques can detect moderate-to-severe injuries, they are relatively insensitive to mTBI. In this study, we used hybrid diffusion imaging (HYDI) to detect white-matter alterations in nineteen patients with mTBI and 23 other trauma-control patients. Within 15 days (SD=10) of brain injury, all subjects underwent magnetic-resonance HYDI and were assessed with battery of neuropsychological tests of sustained attention, memory, and executive function...
May 22, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29786459/anatomy-of-the-attraction-basins-breaking-with-the-intuition
#11
Leticia Hernando, Alexander Mendiburu, Jose A Lozano
Solving combinatorial optimization problems efficiently requires the development of algorithms that consider the specific properties of the problems. In this sense, local search algorithms are designed over a neighborhood structure that partially accounts for these properties. Considering a neighborhood, the space is usually interpreted as a natural landscape, with valleys and mountains. Under this perception, it is commonly believed that, if maximizing, the solutions located in the slopes of the same mountain belong to the same attraction basin, with the peaks of the mountains being the local optima...
May 22, 2018: Evolutionary Computation
https://www.readbyqxmd.com/read/29786430/galaxygpcrloop-template-based-and-ab-initio-structure-sampling-of-the-extracellular-loops-of-g-protein-coupled-receptors
#12
Jonghun Won, Gyu Rie Lee, Hahnbeom Park, Chaok Seok
The second extracellular loops (ECL2s) of G-protein-coupled receptors (GPCRs) are often involved in GPCR functions, and their structures have important implications in drug discovery. However, structure prediction of ECL2 is difficult because of its long length and the structural diversity among different GPCRs. In this study, a new ECL2 conformational sampling method involving both template-based and ab initio sampling was developed. Inspired by observation of similar ECL2 structures of closely related GPCRs, a template-based sampling method employing loop structure templates selected from the structure database was developed...
May 22, 2018: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/29786413/frozen-elephant-trunk-and-arch-endografts-for-chronic-thoracoabdominal-aortic-dissections
#13
Giovanni Tinelli, Marco Ferraresi, A Claire Watkins, Raphael Soler, Elie Fadel, Dominique Fabre, Stéphan Haulon
Chronic aortic dissecting aneurysms (TAAD) presenting after acute Stanford Type A or B dissection includes both arch and/or thoracoabdominal aortic aneurysms (TAAA). Approximately 60% of patients who survive surgical treatment of acute Type A aortic dissections will require another aortic procedure. Similarly, more than 70% of patients with chronic Type B aortic dissections will experience false lumen dilation at 5-year follow-up, often requiring intervention. Open or hybrid aortic repairs of complex TAAD involving the arch and the TAAA are very demanding procedures for both patients and clinicians...
May 22, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29786098/syntheses-structures-and-magnetic-properties-of-three-new-mn-ii-mo-iii-cn-7-4-molecular-magnets
#14
Xiao-Qin Wei, Qian Pi, Fu-Xing Shen, Dong Shao, Hai-Yan Wei, Xin-Yi Wang
By reaction of K4[MoIII(CN)7]·2H2O, Mn(ClO4)2·6H2O and bidentate chelating ligands, three new cyano-bridged compounds, namely Mn2(3-pypz)(H2O)(CH3CN)[Mo(CN)7] (1), Mn2(1-pypz)(H2O)(CH3CN)[Mo(CN)7] (2) and Mn2(pyim)(H2O)(CH3CN)[Mo(CN)7] (3) (3-pypz = 2-(1H-pyrazol-3-yl)pyridine, 1-pypz = 2-(1H-pyrazol-1-yl)pyridine, pyim = 2-(1H-imidazol-2-yl)pyridine), have been synthesized and characterized structurally and magnetically. Single crystal X-ray analyses revealed that although the chelating ligands are different, compounds 1 to 3 are isomorphous and crystallize in the same monoclinic space group C2/m...
May 22, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29785972/a-methodology-to-objectively-assess-the-performance-of-sound-field-amplification-systems-demonstrated-using-50-physical-simulations-of-classroom-conditions
#15
Stephen Dance, Bradford Backus, Lorenzo Morales
Introduction: The effect of a sound reinforcement system, in terms of speech intelligibility, has been systematically determined under realistic conditions. Different combinations of ambient and reverberant conditions representative of a classroom environment have been investigated. Materials and Methods: By comparing the measured speech transmission index metric with and without the system in the same space under different room acoustics conditions, it was possible to determine when the system was most effective...
May 2018: Noise & Health
https://www.readbyqxmd.com/read/29785850/performance-enhancement-of-inverted-perovskite-solar-cells-based-on-smooth-and-compact-pc61bm-sno2-electron-transport-layers
#16
Yao Wang, Chenghao Duan, Jiangsheng Li, Wei Han, Min Zhao, Lili Yao, Yuanyuan Wang, Chao Yan, Tonggang Jiu
In this work, PC61BM:SnO2 electron transport layers (ETLs) were applied in inverted CH3NH3PbI3 perovskite solar cells and a high power conversion efficiency of 19.7% could be obtained. It increased by 49.0% in comparison with the device based on PC61BM-only ETL (13.2%). SnO2 nanocrystals with excellent dispersibility were employed here to fill the pin-holes and cover the valleys of PC61BM layer, forming smooth and compact PC61BM:SnO2 layers. Simultaneously, the electron traps caused by deep-level native defects of SnO2 were reduced by PC61BM proved by the space charge limited current analysis...
May 22, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29785834/development-of-a-robust-mri-fiducial-system-for-automated-fusion-of-mr-us-abdominal-images
#17
Christopher P Favazza, Krzysztof R Gorny, Matthew R Callstrom, Anil N Kurup, Michael Washburn, Pamela S Trester, Charles L Fowler, Nicholas J Hangiandreou
We present the development of a two-component magnetic resonance (MR) fiducial system, that is, a fiducial marker device combined with an auto-segmentation algorithm, designed to be paired with existing ultrasound probe tracking and image fusion technology to automatically fuse MR and ultrasound (US) images. The fiducial device consisted of four ~6.4 mL cylindrical wells filled with 1 g/L copper sulfate solution. The algorithm was designed to automatically segment the device in clinical abdominal MR images...
May 21, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29785801/gold-surface-plasmon-crystal-structure-based-on-polystyrene-template-for-biosensor-application
#18
Min-Zhuo Cheng, Jing Zhang, Dequan Bao, Xiwei Huang
In this communication, we assembled ordered polystyrene (PS) microsphere array as a template with the drop-coating method, and the oxygen plasma was used to etch the template to adjust the spacing between the PS microspheres. Nano-triangular gold array and silver Nano-pyramid array were obtained by ion beam sputtering to deposit precious metal gold and silver. We observed the surface morphology of Au and Au/Ag composite films by scanning electron microscope and characterized the films by X-ray diffraction and Ultraviolet/visible light spectrophotometer...
May 21, 2018: Electrophoresis
https://www.readbyqxmd.com/read/29785608/reuse-of-organobentonites-with-a-carbon-dioxide-responsive-solvent
#19
Ling-Yu Luan, Li Zhang, Li-Hong Wang
Synthesized organobentonite (SOB), montmorillonite (MMT), and commercial organobentonite (COB) were used as adsorbents for paraffin oil, a model pollutant in land-based oil spills and oil pipeline rupture. The characterization of clays was carried out with scanning electron microscopy (SEM), thermogravimetric analysis (TG), Fourier transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD). After adsorption, oil was separated from adsorbents with a carbon dioxide responsive solvent N,N-dimethylcyclohexylamine (DMCHA), and DMCHA was subsequently separated from paraffin oil upon CO2 bubbling instead of distillation with high energy cost...
May 22, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29785561/reptb-a-gene-ontology-based-drug-repurposing-approach-for-tuberculosis
#20
Anurag Passi, Neeraj Kumar Rajput, David J Wild, Anshu Bhardwaj
Tuberculosis (TB) is the world's leading infectious killer with 1.8 million deaths in 2015 as reported by WHO. It is therefore imperative that alternate routes of identification of novel anti-TB compounds are explored given the time and costs involved in new drug discovery process. Towards this, we have developed RepTB. This is a unique drug repurposing approach for TB that uses molecular function correlations among known drug-target pairs to predict novel drug-target interactions. In this study, we have created a Gene Ontology based network containing 26,404 edges, 6630 drug and 4083 target nodes...
May 21, 2018: Journal of Cheminformatics
keyword
keyword
39189
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"