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https://www.readbyqxmd.com/read/28735208/sectoral-linkage-analysis-of-three-main-air-pollutants-in-china-s-industry-comparing-2010-with-2002
#1
Weiwei He, Yuan Wang, Jian Zuo, Yincheng Luo
To investigate the driving forces of air pollution in China, the changes in linkages amongst inter-industrial air pollutant emissions were analyzed by hypothetical extraction method under the input-output framework. Results showed that the emissions of SO2, soot and dust from industrial sources increased by 56.46%, 36.95% and 11.69% respectively in 2010, compared with 2002. As major contributors to emissions, the power and gas sectors were responsible for the growing SO2 emissions, the nonmetal products sector for soot emissions, and the metals mining, smelting and pressing sectors for dust emissions...
July 20, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28734852/azodicarbonamide-adca-a-reconsideration-of-classification-as-a-respiratory-sensitiser
#2
Josje Arts, Ian Kimber
Azodicarbonamide (ADCA) is widely used by industry in the manufacture of a variety of products. ADCA has been classified as a respiratory allergen, and the purpose of this article was to consider whether this classification is appropriate based upon the available data. Here both clinical experience and relevant experimental data have been reviewed. Although there have been reports of an association between workplace exposure to ADCA and symptoms of respiratory allergy and occupational asthma, the evidence is less than persuasive, with in many instances a lack of properly controlled and executed diagnostic procedures...
July 19, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28734259/polishability-and-wear-resistance-of-splint-material-for-oral-appliances-produced-with-conventional-subtractive-and-additive-manufacturing
#3
Fabian Huettig, Achim Kustermann, Ebru Kuscu, Jürgen Geis-Gerstorfer, Sebastian Spintzyk
Occlusal splints to treat bruxism are commonly made from polymethylmethacrylate (PMMA) in a manual workflow (powder-liquid technique). Today digitalization allows a machine-based manufacturing in subtractive (milling) and additive (printing) means using industrial-made PMMA or comparable resins. An in-vitro study should assess the surface finish and screen the wear resistance of conventional and industrial materials. Therefore, a total of 30 specimens made from conventionally PMMA (group C; powder-liquid, Palapress), polycarbonate ingots (group S; innoBlanc splint plus), and light-curing resin (group A; VarseoWax splint) were polished to examine the surface roughness (Ra) by profilometry and further analyzed by SEM...
July 14, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28733131/preclinical-studies-for-a-phase-1-clinical-trial-of-autologous-hematopoietic-stem-cell-gene-therapy-for-sickle-cell-disease
#4
Fabrizia Urbinati, Jennifer Wherley, Sabine Geiger, Beatriz Campo Fernandez, Michael L Kaufman, Aaron Cooper, Zulema Romero, Filippo Marchioni, Lilith Reeves, Elizabeth Read, Barbara Nowicki, Elke Grassman, Shivkumar Viswanathan, Xiaoyan Wang, Roger P Hollis, Donald B Kohn
BACKGROUND AIMS: Gene therapy by autologous hematopoietic stem cell transplantation (HSCT) represents a new approach to treat sickle cell disease (SCD). Optimization of the manufacture, characterization and testing of the transduced hematopoietic stem cell final cell product (FCP), as well as an in depth in vivo toxicology study, are critical for advancing this approach to clinical trials. METHODS: Data are shown to evaluate and establish the feasibility of isolating, transducing with the Lenti/β(AS3)-FB vector and cryopreserving CD34(+) cells from human bone marrow (BM) at clinical scale...
July 18, 2017: Cytotherapy
https://www.readbyqxmd.com/read/28731889/stent-thrombosis-with-bioabsorbable-polymer-drug-eluting-stents-insights-from-the-food-and-drug-administration-database
#5
Abdur R Khan, Avnish Tripathi, Talha A Farid, Bilal Abaid, Deepak L Bhatt, Jon R Resar, Michael P Flaherty
BACKGROUND: SYNERGY, a bioabsorbable polymer-based, everolimus-eluting stent (BP-DES), recently received regulatory approval in the USA for use in percutaneous coronary interventions. Yet, information on the safety of BP-DES in routine clinical practice is limited. Our aim was to compare the safety of the recently approved BP-DES with current durable polymer drug-eluting stents (DP-DES) by analyzing adverse events, namely, stent thrombosis (ST), reported to the Manufacturer and User Facility Device Experience (MAUDE) database...
July 20, 2017: Coronary Artery Disease
https://www.readbyqxmd.com/read/28731270/polarized-light-emitting-diodes-based-on-patterned-mos2-nanosheet-hole-transport-layer
#6
Gyu Jin Choi, Quyet Van Le, Kyoung Soon Choi, Ki Chang Kwon, Ho Won Jang, Jin Seog Gwag, Soo Young Kim
Here, this study successfully fabricates few-layer MoS2 nanosheets from (NH4 )2 MoS4 and applies them as the hole transport layer as well as the template for highly polarized organic light-emitting diodes (OLEDs). The obtained material consists of polycrystalline MoS2 nanosheets with thicknesses of 2 nm. The MoS2 nanosheets are patterned by rubbing/ion-beam treatment. The Raman spectra shows that {poly(9,9-dioctylfluorene-alt-benzothiadiazole), poly[(9,9-di-n-octylfluorenyl-2,7-diyl)-alt-(benzo[2,1,3]thiadiazol-4,8-diyl)]} (F8BT) on patterned MoS2 exhibits distinctive polarization behavior...
July 21, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28730874/abortion-politics-in-cambodia-social-history-local-forms-and-transnational-issues
#7
Pascale Hancart Petitet
Cambodia's current abortion rate and ratio could be among the highest in Southeast Asia. In 1997, the Cambodian parliament passed the first law regulating abortions. This law was adopted to contribute to reduce the high maternal mortality ratio, as a significant number of maternal deaths were believed to be related to complications of unsafe abortion. A decade later, the Ministry of Health had not yet established medical protocols for safe abortion access and women often continued to induce their own terminations or seek unsafe services...
July 21, 2017: Global Public Health
https://www.readbyqxmd.com/read/28729909/biological-effects-and-mechanisms-of-shortwave-radiation-a-review
#8
REVIEW
Chao Yu, Rui-Yun Peng
With the increasing knowledge of shortwave radiation, it is widely used in wireless communications, radar observations, industrial manufacturing, and medical treatments. Despite of the benefits from shortwave, these wide applications expose humans to the risk of shortwave electromagnetic radiation, which is alleged to cause potential damage to biological systems. This review focused on the exposure to shortwave electromagnetic radiation, considering in vitro, in vivo and epidemiological results that have provided insight into the biological effects and mechanisms of shortwave...
2017: Military Medical Research
https://www.readbyqxmd.com/read/28729228/tangled-history-of-the-european-uses-of-sphagnum-moss-and-sphagnol
#9
REVIEW
Jacek Drobnik, Adam Stebel
ETHNOPHARMACOLOGICAL RELEVANCE: Sphagnum mosses and peat could have been utilized as wound dressings for centuries, however reliable data on this subject are ambiguous; sometimes even no distinction between peat moss (Sphagnum spp.) and peat is made or these terms become confused. The first scientific account on surgical use of peat comes from 1882: a peat digger who successfully, by himself and in the way unknown to the then medicine, cured an open fracture of his forearm with peat. The peat, and very soon the peat moss itself (which is the major constituent of peat) drew attention of the 19(th)-century surgeons...
July 17, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28729216/self-assembled-aunps-for-ingrain-pigmentation-of-silk-fabrics-with-antibacterial-potency
#10
Hanan B Ahmed, Nancy S El-Hawary, Hossam E Emam
Nanogold was self-assembled for ingrain pigmentation of silk fabric with antibacterial properties. The functional groups of silk macromolecular polymeric chains were exploited for generation and stabilization of nanogold. Hydrogen peroxide was used for activation of silk molecular chains through increasing their reactivity and accessibility to be functionalized as manufacturer of nanogold without using any external agents. Effect of procedure sequencing was studied through addition of peroxide firstly (group A) and with Au salt (group B)...
July 17, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28728084/purification-of-monoclonal-antibodies-entirely-in-flow-through-mode
#11
Tsuyoshi Yamada, Koichi Yamamoto, Takashi Ishihara, Shigeru Ohta
A depth filter is widely used in biopharmaceutical manufacturing process. In this study, we found that buffer exchange to reduce conductivity dramatically improved the removal of impurities in depth filtration. The host cell protein clearance was comparable to that of protein A affinity chromatography, which is generally used as a first capture step in monoclonal antibody purification. In addition, a combination of different depth filters showed enhanced purification. Additional flow-through purification is possible without any sample preparation, and a biopharmaceutical-quality purity level (<100ppm for host cell protein and <5% for high molecular weight species) can be attained...
July 3, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28727773/the-tradition-algorithm-approach-underestimates-the-prevalence-of-serodiagnosis-of-syphilis-in-hiv-infected-individuals
#12
Bin Chen, Xiuming Peng, Tiansheng Xie, Changzhong Jin, Fumin Liu, Nanping Wu
Currently, there are three algorithms for screening of syphilis: traditional algorithm, reverse algorithm and European Centre for Disease Prevention and Control (ECDC) algorithm. To date, there is not a generally recognized diagnostic algorithm. When syphilis meets HIV, the situation is even more complex. To evaluate their screening performance and impact on the seroprevalence of syphilis in HIV-infected individuals, we conducted a cross-sectional study included 865 serum samples from HIV-infected patients in a tertiary hospital...
July 20, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28727677/surveillance-for-silicosis-deaths-among-persons-aged-15-44-years-united-states-1999-2015
#13
Jacek M Mazurek, John M Wood, Patricia L Schleiff, David N Weissman
Silicosis is usually a disease of long latency affecting mostly older workers; therefore, silicosis deaths in young adults (aged 15-44 years) suggests acute or accelerated disease.* To understand the circumstances surrounding silicosis deaths among young persons, CDC analyzed the underlying and contributing causes(†) of death using multiple cause-of-death data (1999-2015) and industry and occupation information abstracted from death certificates (1999-2013). During 1999-2015, among 55 pneumoconiosis deaths of young adults with International Classification of Diseases, Tenth Revision (ICD-10) code J62 (pneumoconiosis due to dust containing silica),(§) 38 (69%) had code J62...
July 21, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28726738/scheduling-for-emergency-tasks-in-industrial-wireless-sensor-networks
#14
Changqing Xia, Xi Jin, Linghe Kong, Peng Zeng
Wireless sensor networks (WSNs) are widely applied in industrial manufacturing systems. By means of centralized control, the real-time requirement and reliability can be provided by WSNs in industrial production. Furthermore, many approaches reserve resources for situations in which the controller cannot perform centralized resource allocation. The controller assigns these resources as it becomes aware of when and where accidents have occurred. However, the reserved resources are limited, and such incidents are low-probability events...
July 20, 2017: Sensors
https://www.readbyqxmd.com/read/28726228/microwave-irradiation-and-citric-acid-assisted-seed-germination-and-phytoextraction-of-nickel-ni-by-brassica-napus-l-morpho-physiological-and-biochemical-alterations-under-ni-stress
#15
Mujahid Farid, Shafaqat Ali, Muhammad Rizwan, Rashid Saeed, Hafiz Muhammad Tauqeer, Rasham Sallah-Ud-Din, Ahmed Azam, Nighat Raza
The complex bio-geochemistry of soil allows pollutant to persist for a longer period of time which further decreased the fertility and natural composition of land. Nickel, an inorganic pollutant, coming from a wide range of industrial and manufacturing units possesses serious threat to soil degradation and crop productivity around the world. The present study was carried to evaluate the combined role of microwave irradiation (MR) and citric acid (CA) on the phytoextraction potential of Brassica napus L. under Ni stress...
July 20, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28722629/estimating-the-added-utility-of-highly-sensitive-histidine-rich-protein-2-detection-in-outpatient-clinics-in-sub-saharan-africa
#16
Mateusz M Plucinski, Eric Rogier, Pedro Rafael Dimbu, Filomeno Fortes, Eric S Halsey, Michael Aidoo
Most malaria testing is by rapid diagnostic tests (RDTs) that detect Plasmodium falciparum histidine-rich protein 2 (HRP2). Recently, several RDT manufacturers have developed highly sensitive RDTs (hsRDTs), promising a limit of detection (LOD) orders of magnitude lower than conventional RDTs. To model the added utility of hsRDTs, HRP2 concentration in Angolan outpatients was measured quantitatively using an ultrasensitive bead-based assay. The distribution of HRP2 concentration was bimodal in both afebrile and febrile patients...
June 12, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28721849/effective-protection-of-mice-against-shigella-flexneri-with-a-new-self-adjuvant-multicomponent-vaccine
#17
Yadira Pastor, Ana Camacho, Ana Gloria Gil, Rocío Ramos, Adela López de Ceráin, Iván Peñuelas, Juan M Irache, Carlos Gamazo
PURPOSE: The aim of this study was to develop an immunogenic protective product against Shigella flexneri by employing a simple and safe heat treatment-based strategy. METHODOLOGY: The physicochemical characteristics of naturally produced (OMV) and heat-induced (HT) outer-membrane vesicles from S. flexneri were examined, including a comparison of the protein content of the products. Toxicological and biodistribution studies, and a preliminary experiment to examine the protective effectiveness of HT in a murine model of S...
July 18, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28721305/fully-automated-gmp-production-of-68-ga-ga-do3a-vs-cys-40-exendin-4-for-clinical-use
#18
Irina Velikyan, Ulrika Rosenstrom, Olof Eriksson
[(68)Ga]Ga-DO3A-VS-Cys(40)-Exendin-4/PET-CT targeting glucagon like peptide-1 receptor (GLP-1R) has previously demonstrated its potential clinical value for the detection of insulinomas. The production and accessibility of this radiopharmaceutical is one of the critical factors in realization of clinical trials and routine clinical examinations. Previously, the radiopharmaceutical was prepared manually, however larger scale of clinical trials and healthcare requires automation of the production process in order to limit the operator radiation dose as well as improve tracer manufacturing robustness and on-line documentation for enhanced good manufacturing practice (GMP) compliance...
2017: American Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28720960/levels-and-formation-of-%C3%AE-dicarbonyl-compounds-in-beverages-and-the-preventive-effects-of-flavonoids
#19
Chen Wang, Yongling Lu, Qiju Huang, Tiesong Zheng, Shengmin Sang, Lishuang Lv
ABSTRACT: Methylglyoxal (MGO) and glyoxal (GO), α-dicarbonyl compounds found in the Maillard reaction, progressively and irreversibly modify proteins. Beverages are an exogenous source of α-dicarbonyl compounds and may potentially increase MGO and GO levels in vivo. Using GC-FID method, we detected the MGO and GO contents of 86 beverages in Chinese supermarkets. The highest MGO and GO 587.5 µg/100 mL and 716.7 µg/100 mL respectively found in soyamilk and coffee. Herbal beverages, which contained bioactive components, had lower average levels of MGO (48...
June 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28720339/in%C3%A2-vitro-fit-of-cad-cam-complete-arch-screw-retained-titanium-and-zirconia-implant-prostheses-fabricated-on-4-implants
#20
Hadi Al-Meraikhi, Burak Yilmaz, Edwin McGlumphy, William Brantley, William M Johnston
STATEMENT OF PROBLEM: Computer-aided designed and computer-aided manufactured (CAD-CAM) titanium and zirconia implant-supported fixed implant prostheses on 4 implants have become popular. The precision and accuracy of their interface fit has not been widely researched. PURPOSE: The purpose of this in vitro study was to compare the marginal fit of zirconia and titanium implant-supported screw-retained CAD-CAM complete fixed dental prostheses (CFDP) fit with a standardized cast simulating the all-on-4 implant distribution...
July 15, 2017: Journal of Prosthetic Dentistry
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