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https://www.readbyqxmd.com/read/28802950/application-of-dye-analysis-in-forensic-fibre-and-textile-examination-case-examples
#1
Tom G Schotman, Xiaoma Xu, Nicole Rodewijk, Jaap van der Weerd
Seven cases and a quality assurance test are presented. In these cases, fibres or textiles submitted for investigation were analysed by HPLC-DAD-MS to identify the dyes present. The cases presented illustrate that it is possible to identify textile dyes in fibre traces recovered for forensic analysis. The results show that a mixture of dyes is present in all textiles investigated, except one sample that was taken from a manufacturer dye shade card. It is concluded that dye analyses improves the evidential value of forensic fibre examinations, as it becomes possible to distinguish textiles that are different in dye chemistry, but have a similar colour...
July 31, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28801849/bevacizumab-in-colorectal-cancer-current-role-in-treatment-and-the-potential-of-biosimilars
#2
REVIEW
Lee S Rosen, Ira A Jacobs, Ronald L Burkes
Colorectal cancer (CRC) is a leading cause of tumor-related morbidity and mortality worldwide, with mortality most often attributable to metastatic disease. Bevacizumab, a humanized monoclonal antibody targeting vascular endothelial growth factor, has a significant role in the treatment of metastatic CRC (mCRC). However, patient access to bevacizumab may be limited in some regions or circumstances, owing to factors related to insurance coverage, reimbursement, patient out-of-pocket costs, or availability. As a result, outcomes for patients with mCRC may be worsened...
August 11, 2017: Targeted Oncology
https://www.readbyqxmd.com/read/28801839/biotransformation-with-cellulase-hemicellulase-and-yarrowia-lipolytica-boosts-health-benefits-of-okara
#3
Weng Chan Vong, Xin Ying Lim, Shao-Quan Liu
Okara (soybean residue) is a highly perishable food processing by-product from soymilk and tofu manufacture. It contains a large proportion of insoluble dietary fibre (40-60% on a dry basis), as well as digestion-resistant proteins, trypsin inhibitors and phytic acid. These factors contribute lead to the under-utilisation of okara. To improve the overall nutritional quality of okara, sequential saccharification of okara by Celluclast® 1.5L (cellulase) or Viscozyme® L (cellulase and hemicellulase) and fermentation by the yeast Yarrowia lipolytica were performed...
August 11, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28799741/early-assessment-and-correlations-of-nanoclay-s-toxicity-to-their-physical-and-chemical-properties
#4
Alixandra Wagner, Andrew White, Todd A Stueckle, Derrick Banerjee, Konstantinos A Sierros, Yon Rojanasakul, Sushant Agarwal, Rakesh K Gupta, Cerasela Zoica Dinu
Nanoclays' functionalization with organic modifiers increases their individual barrier properties, thermal stability, and mechanical properties and allows for ease of implementation in food packaging materials or medical devices. Previous reports have showed that while organic modifiers integration between the layered mineral silicates leads to nanoclays with different degrees of hydrophobicity that become easily miscible in polymers, they could also pose possible effects at inhalation or ingestion routes of exposure...
August 11, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28799050/environmental-building-policy-by-the-use-of-microalgae-and-decreasing-of-risks-for-canadian-oil-sand-sector-development
#5
Armen B Avagyan
Environmental building recommendations aimed towards new environmental policies and management-changing decisions which as example demonstrated in consideration of the problems of Canadian oil sands operators. For the implementation of the circular economic strategy, we use an in-depth analysis of reported environmental after-consequence on all stages of the production process. The study addressed the promotion of innovative solutions for greenhouse gas emission, waste mitigation, and risk of falling in oil prices for operators of oil sands with creating market opportunities...
August 10, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28798872/fiber-reinforced-scaffolds-in-soft-tissue-engineering
#6
REVIEW
Baoqing Pei, Wei Wang, Yubo Fan, Xiumei Wang, Fumio Watari, Xiaoming Li
Soft tissue engineering has been developed as a new strategy for repairing damaged or diseased soft tissues and organs to overcome the limitations of current therapies. Since most of soft tissues in the human body are usually supported by collagen fibers to form a three-dimensional microstructure, fiber-reinforced scaffolds have the advantage to mimic the structure, mechanical and biological environment of natural soft tissues, which benefits for their regeneration and remodeling. This article reviews and discusses the latest research advances on design and manufacture of novel fiber-reinforced scaffolds for soft tissue repair and how fiber addition affects their structural characteristics, mechanical strength and biological activities in vitro and in vivo...
August 2017: Regenerative Biomaterials
https://www.readbyqxmd.com/read/28797120/medication-eluting-devices-for-the-field-of-obgyn-medobgyn-3d-printed-biodegradable-hormone-eluting-constructs-a-proof-of-concept-study
#7
Karthik Tappa, Udayabhanu Jammalamadaka, David H Ballard, Todd Bruno, Marissa R Israel, Harika Vemula, J Mark Meacham, David K Mills, Pamela K Woodard, Jeffery A Weisman
3D printing has the potential to deliver personalized implants and devices for obstetric and gynecologic applications. The aim of this study is to engineer customizable and biodegradable 3D printed implant materials that can elute estrogen and/or progesterone. All 3D constructs were printed using polycaprolactone (PCL) biodegradable polymer laden with estrogen or progesterone and were subjected to hormone-release profile studies using ELISA kits. Material thermal properties were tested using thermogravimetric analysis and differential scanning calorimetry...
2017: PloS One
https://www.readbyqxmd.com/read/28796824/droplet-digital-polymerase-chain-reaction-ddpcr-assays-integrated-with-an-internal-control-for-quantification-of-bovine-porcine-chicken-and-turkey-species-in-food-and-feed
#8
Hanan R Shehata, Jiping Li, Shu Chen, Helen Redda, Shumei Cheng, Nicole Tabujara, Honghong Li, Keith Warriner, Robert Hanner
Food adulteration and feed contamination are significant issues in the food/feed industry, especially for meat products. Reliable techniques are needed to monitor these issues. Droplet Digital PCR (ddPCR) assays were developed and evaluated for detection and quantification of bovine, porcine, chicken and turkey DNA in food and feed samples. The ddPCR methods were designed based on mitochondrial DNA sequences and integrated with an artificial recombinant plasmid DNA to control variabilities in PCR procedures...
2017: PloS One
https://www.readbyqxmd.com/read/28795951/gelma-collagen-blends-enable-drop-on-demand-3d-printablility-and-promote-angiogenesis
#9
Henrike Stratesteffen, Marius Johannes Köpf, Franziska Kreimendahl, Andreas Blaeser, Stefan Jockenhoevel, Horst Fischer
Effective vascularization is crucial for three dimensional (3D) printed hydrogel-cell constructs to efficiently supply cells with oxygen and nutrients. Till date, several hydrogel blends have been developed that allow the in vitro formation of a capillary-like network within the gels but comparatively less effort has been made to improve the suitability of the materials for a 3D bioprinting process. Therefore, we hypothesize that tailored hydrogel blends of photo-crosslinkable gelatin and type I collagen exhibit favorable 3D drop-on-demand printing characteristics in terms of rheological and mechanical properties and that further capillary-like network formation can be induced by co-culturing human umbilical vein endothelial cells (HUVEC) and human mesenchymal stem cells (hMSC) within the proposed blends...
August 10, 2017: Biofabrication
https://www.readbyqxmd.com/read/28795521/liquid-tubule-formation-and-stabilization-using-cellulose-nanocrystal-surfactants
#10
Xubo Liu, Shaowei Shi, Yanan Li, Joe Forth, Dong Wang, Thomas P Russell
Structured liquids, generated by the in situ interfacial generation, assembly and jamming of nanoparticle (NP)-surfactants at liquid interfaces, maintain all the desirable characteristics of each liquid, while providing a spatially structured frame work. Here, we show that rod-like cellulose nanocrystal (CNC)-based NP-surfactants, termed CNC-surfactants, are formed rapidly at the liquid/liquid interface, assemble into a monolayer, and, when jammed, offer a robust assembly with exceptional mechanical properties...
August 9, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28795377/comparison-of-the-fatty-acid-profile-of-spanish-infant-formulas-and-galician-women-breast-milk
#11
Rocío Barreiro, Patricia Regal, Olga López-Racamonde, Alberto Cepeda, Cristina A Fente
The importance of dietary lipids during childhood is evident, as they are necessary for correct growth and development of the newborn. When breastfeeding is not possible, infant formulas are designed to mimic human milk as much as possible to fulfill infant's requirements. However, the composition of these dairy products is relatively constant, while human milk is not a uniform bio-fluid and changes according to the requirements of the baby. In this study, breast milk samples were donated by 24 Spanish mothers in different lactation stages and different infant formulas were purchased in supermarkets and pharmacies...
August 9, 2017: Journal of Physiology and Biochemistry
https://www.readbyqxmd.com/read/28795201/downstream-processing-technologies-capturing-and-final-purification-opportunities-for-innovation-change-and-improvement-a-review-of-downstream-processing-developments-in-protein-purification
#12
Nripen Singh, Sibylle Herzer
Increased pressure on upstream processes to maximize productivity has been crowned with great success, although at the cost of shifting the bottleneck to purification. As drivers were economical, focus is on now on debottlenecking downstream processes as the main drivers of high manufacturing cost. Devising a holistically efficient and economical process remains a key challenge. Traditional and emerging protein purification strategies with particular emphasis on methodologies implemented for the production of recombinant proteins of biopharmaceutical importance are reviewed...
August 10, 2017: Advances in Biochemical Engineering/biotechnology
https://www.readbyqxmd.com/read/28793108/validation-of-educational-booklet-for-hiv-aids-prevention-in-older-adults
#13
Luana Ibiapina Cordeiro, Thais de Oliveira Lopes, Luciane Elise de Abreu Lira, Sarah Maria de Sousa Feitoza, Maria Eliana Peixoto Bessa, Maria Lúcia Duarte Pereira, Aline Rodrigues Feitoza, Adriano Rodrigues de Souza
Objective: To describe the process of manufacturing and validation of an educational booklet for HIV/Aids prevention in older adults. Methods: Methodological study developed in two phases - manufacturing of the booklet and validation of the educational material by judges. The manufacturing process involved a situational diagnosis with older adults, and its result indicated gaps in the knowledge with respect to HIV/Aids. The validation process was performed by nine judges, selected by convenience...
July 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28783068/a-highly-sensitive-nonenzymatic-glucose-biosensor-based-on-the-regulatory-effect-of-glucose-on-electrochemical-behaviors-of-colloidal-silver-nanoparticles-on-mos%C3%A2-%C3%A2
#14
Kash Anderson, Benjamin Poulter, John Dudgeon, Shu-En Li, Xiang Ma
A novel and highly sensitive nonenzymatic glucose biosensor was developed by nucleating colloidal silver nanoparticles (AgNPs) on MoS₂. The facile fabrication method, high reproducibility (97.5%) and stability indicates a promising capability for large-scale manufacturing. Additionally, the excellent sensitivity (9044.6 μA mM(-1) cm(-2)), low detection limit (0.03 μM), appropriate linear range of 0.1-1000 μM, and high selectivity suggests that this biosensor has a great potential to be applied for noninvasive glucose detection in human body fluids, such as sweat and saliva...
August 5, 2017: Sensors
https://www.readbyqxmd.com/read/28782523/monitoring-native-hla-i-trimer-specific-antibodies-in-luminex-multiplex-single-antigen-bead-assay-evaluation-of-beadsets-from-different-manufacturers
#15
Mepur H Ravindranath, Vadim Jucaud, Soldano Ferrone
Luminex single antigen bead (SAB) assay utilizes beadsets coated with a set of cloned and purified HLA molecules, for monitoring serum anti-HLA antibodies. Particularly, the level of serum IgG against native HLA-I trimers (heavy chain (HC) and β2-microglobulin (β2m) with a peptide), expressed in allograft tissues is correlated with graft failure. In addition to native trimeric HLAI, the beadsets may carry HC only or the dimeric variants, peptide-free HC with β2m and β2m-free HC with or without peptides...
August 4, 2017: Journal of Immunological Methods
https://www.readbyqxmd.com/read/28782006/nondestructive-imaging-of-atomically-thin-nanostructures-buried-in-silicon
#16
Georg Gramse, Alexander Kölker, Tingbin Lim, Taylor J Z Stock, Hari Solanki, Steven R Schofield, Enrico Brinciotti, Gabriel Aeppli, Ferry Kienberger, Neil J Curson
It is now possible to create atomically thin regions of dopant atoms in silicon patterned with lateral dimensions ranging from the atomic scale (angstroms) to micrometers. These structures are building blocks of quantum devices for physics research and they are likely also to serve as key components of devices for next-generation classical and quantum information processing. Until now, the characteristics of buried dopant nanostructures could only be inferred from destructive techniques and/or the performance of the final electronic device; this severely limits engineering and manufacture of real-world devices based on atomic-scale lithography...
June 2017: Science Advances
https://www.readbyqxmd.com/read/28781718/a-partially-hydrolyzed-100-whey-formula-and-the-risk-of-eczema-and-any-allergy-an-updated-meta-analysis
#17
REVIEW
Hania Szajewska, Andrea Horvath
BACKGROUND: Recently, the role of using hydrolyzed formula for the prevention of allergic disease has been questioned. However, not all hydrolyzed formulas are equal. The efficacy of each hydrolyzed formula should be established separately. We updated evidence on the effectiveness of using partially hydrolyzed 100% whey formula (pHF), manufactured by a single manufacturer, for reducing the risk of eczema and allergy in healthy infants at high risk for allergy. METHODS: The Cochrane Library, MEDLINE, and EMBASE databases were searched in June 2016 for randomized and quasi-randomized controlled trials (RCTs); additional data were obtained from reviewed articles and the authors of included trials...
2017: World Allergy Organization Journal
https://www.readbyqxmd.com/read/28781073/accuracy-of-stereolithography-additive-casts-used-in-a-digital-workflow
#18
Hiba Al-Imam, Mia Gram, Ana R Benetti, Klaus Gotfredsen
STATEMENT OF PROBLEM: Despite the increasing demand for a digital workflow in the fabrication of indirect restorations, information on the accuracy of the resulting definitive casts is limited. PURPOSE: The purpose of this in vitro study was to compare the accuracy of definitive casts produced with digital scans and conventional impressions. MATERIAL AND METHODS: Chamfer preparations were made on the maxillary right canine and second molar of a typodont...
August 4, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28781071/effect-of-thixotropic-agents-as-additives-on-the-mechanical-properties-of-maxillofacial-silicone-elastomers
#19
Abdel Rahim M Bibars, Zeid Al-Hourani, Yousef Khader, Mark Waters
STATEMENT OF PROBLEM: The incorporation of thixotropic agents to prevent slumping during the silicone packing procedure may alter some favorable mechanical properties of the silicone elastomers and could possibly influence the success of the prosthesis. PURPOSE: The purpose of this in vitro study was to evaluate the effect of adding thixotropic agents on the mechanical properties of 3 commonly used silicone elastomers. MATERIAL AND METHODS: Specimens of 3 maxillofacial silicones (M511, Z004; Technovent Ltd, and A2000; Factor II Inc) were prepared according to the manufacturers' instructions...
August 4, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28780485/selectivity-of-commercial-immunoaffinity-columns-for-modified-forms-of-the-mycotoxin-4-deoxynivalenol-don
#20
Silvio Uhlig, Ana Stanic, Fozia Hussain, Christopher O Miles
Commercial immunoaffinity columns (IACs) are today available for all major mycotoxins. However, manufacturers give usually no or very limited information on the epitope, i.e. the specific part of the toxin molecule that binds to the antibody. 4-Deoxynivalenol (DON) is a trichothecene mycotoxin that is produced by plant pathogenic field fungi and is regulated in many countries worldwide. DON was shown to be biotransformed via different metabolic pathways, and thus many different biotransformation products may be found in different products or organisms...
July 11, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
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