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Medical informatics

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https://www.readbyqxmd.com/read/27913029/pharmacovigilance-and-biomedical-informatics-a-model-for-future-development
#1
Paul Beninger, Michael A Ibara
PURPOSE: The discipline of pharmacovigilance is rooted in the aftermath of the thalidomide tragedy of 1961. It has evolved as a result of collaborative efforts by many individuals and organizations, including physicians, patients, Health Authorities, universities, industry, the World Health Organization, the Council for International Organizations of Medical Sciences, and the International Conference on Harmonisation. Biomedical informatics is rooted in technologically based methodologies and has evolved at the speed of computer technology...
November 29, 2016: Clinical Therapeutics
https://www.readbyqxmd.com/read/27891528/preparing-nursing-home-data-from-multiple-sites-for-clinical-research-a-case-study-using-observational-health-data-sciences-and-informatics
#2
Richard D Boyce, Steven M Handler, Jordan F Karp, Subashan Perera, Charles F Reynolds
INTRODUCTION: A potential barrier to nursing home research is the limited availability of research quality data in electronic form. We describe a case study of converting electronic health data from five skilled nursing facilities to a research quality longitudinal dataset by means of open-source tools produced by the Observational Health Data Sciences and Informatics (OHDSI) collaborative. METHODS: The Long-Term Care Minimum Data Set (MDS), drug dispensing, and fall incident data from five SNFs were extracted, translated, and loaded into version 4 of the OHDSI common data model...
2016: EGEMS
https://www.readbyqxmd.com/read/27885364/bidirectional-rnn-for-medical-event-detection-in-electronic-health-records
#3
Abhyuday N Jagannatha, Hong Yu
Sequence labeling for extraction of medical events and their attributes from unstructured text in Electronic Health Record (EHR) notes is a key step towards semantic understanding of EHRs. It has important applications in health informatics including pharmacovigilance and drug surveillance. The state of the art supervised machine learning models in this domain are based on Conditional Random Fields (CRFs) with features calculated from fixed context windows. In this application, we explored recurrent neural network frameworks and show that they significantly out-performed the CRF models...
June 2016: Proceedings of the Conference
https://www.readbyqxmd.com/read/27875988/common-data-elements-for-secondary-use-of-electronic-health-record-data-for-clinical-trial-execution-and-serious-adverse-event-reporting
#4
Philipp Bruland, Mark McGilchrist, Eric Zapletal, Dionisio Acosta, Johann Proeve, Scott Askin, Thomas Ganslandt, Justin Doods, Martin Dugas
BACKGROUND: Data capture is one of the most expensive phases during the conduct of a clinical trial and the increasing use of electronic health records (EHR) offers significant savings to clinical research. To facilitate these secondary uses of routinely collected patient data, it is beneficial to know what data elements are captured in clinical trials. Therefore our aim here is to determine the most commonly used data elements in clinical trials and their availability in hospital EHR systems...
November 22, 2016: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/27866956/accuracy-and-completeness-of-drug-information-in-wikipedia-medication-monographs
#5
Timothy Reilly, William Jackson, Victoria Berger, Danielle Candelario
OBJECTIVES: The primary objective of this study was to determine the accuracy and completeness of drug information on Wikipedia and Micromedex compared with U.S. Food and Drug Administration-approved U.S. product inserts. METHODS: The top 10 brand and top 10 generic medications from the 2012 Institute for Health Informatics' list of top 200 drugs were selected for evaluation. Wikipedia medication information was evaluated and compared with Micromedex in 7 sections of drug information; the U...
November 17, 2016: Journal of the American Pharmacists Association: JAPhA
https://www.readbyqxmd.com/read/27863959/transmission-of-staphylococcus-aureus-between-health-care-workers-the-environment-and-patients-in-an-intensive-care-unit-a-longitudinal-cohort-study-based-on-whole-genome-sequencing
#6
James R Price, Kevin Cole, Andrew Bexley, Vasiliki Kostiou, David W Eyre, Tanya Golubchik, Daniel J Wilson, Derrick W Crook, A Sarah Walker, Timothy E A Peto, Martin J Llewelyn, John Paul
BACKGROUND: Health-care workers have been implicated in nosocomial outbreaks of Staphylococcus aureus, but the dearth of evidence from non-outbreak situations means that routine health-care worker screening and S aureus eradication are controversial. We aimed to determine how often S aureus is transmitted from health-care workers or the environment to patients in an intensive care unit (ICU) and a high-dependency unit (HDU) where standard infection control measures were in place. METHODS: In this longitudinal cohort study, we systematically sampled health-care workers, the environment, and patients over 14 months at the ICU and HDU of the Royal Sussex County Hospital, Brighton, England...
November 15, 2016: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/27862888/brometh-methodology-to-design-safe-reconfigurable-medical-robotic-systems
#7
Mohamed Oussama Ben Salem, Olfa Mosbahi, Mohamed Khalgui, Zied Jlalia, Georg Frey, Mahmoud Smida
BACKGROUND: This research paper deals with the development of a medical robotized control system for supracondylar humeral fracture treatment. Concurrent access to shared resources and applying reconfiguration scenarios can jeopardize the safety of the system. METHODS: A new methodology is proposed in this paper, termed BROMETH, to guarantee the safety of such critical systems from their specification to their deployment, and passing through certification and implementation...
November 14, 2016: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/27857824/medical-image-encryption-an-application-for-improved-padding-based-ggh-encryption-algorithm
#8
Massoud Sokouti, Ali Zakerolhosseini, Babak Sokouti
Medical images are regarded as important and sensitive data in the medical informatics systems. For transferring medical images over an insecure network, developing a secure encryption algorithm is necessary. Among the three main properties of security services ( i.e. , confidentiality, integrity, and availability), the confidentiality is the most essential feature for exchanging medical images among physicians. The Goldreich Goldwasser Halevi (GGH) algorithm can be a good choice for encrypting medical images as both the algorithm and sensitive data are represented by numeric matrices...
2016: Open Medical Informatics Journal
https://www.readbyqxmd.com/read/27849584/lifestyle-chemistries-from-phones-for-individual-profiling
#9
Amina Bouslimani, Alexey V Melnik, Zhenjiang Xu, Amnon Amir, Ricardo R da Silva, Mingxun Wang, Nuno Bandeira, Theodore Alexandrov, Rob Knight, Pieter C Dorrestein
Imagine a scenario where personal belongings such as pens, keys, phones, or handbags are found at an investigative site. It is often valuable to the investigative team that is trying to trace back the belongings to an individual to understand their personal habits, even when DNA evidence is also available. Here, we develop an approach to translate chemistries recovered from personal objects such as phones into a lifestyle sketch of the owner, using mass spectrometry and informatics approaches. Our results show that phones' chemistries reflect a personalized lifestyle profile...
November 29, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27847328/methodological-framework-for-evaluating-clinical-processes-a-cognitive-informatics-perspective
#10
Thomas G Kannampallil, Joanna Abraham, Vimla L Patel
We propose a methodological framework for evaluating clinical cognitive activities in complex real-world environments that provides a guiding framework for characterizing the patterns of activities. This approach, which we refer to as a process-based approach, is particularly relevant to cognitive informatics (CI) research-an interdisciplinary domain utilizing cognitive approaches in the study of computing systems and applications-as it provides new ways for understanding human information processing, interactions, and behaviors...
December 2016: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/27830261/nursing-informatics-certification-worldwide-history-pathway-roles-and-motivation
#11
Mollie R Cummins, Adi V Gundlapalli, Aditya V Gundlapalli, Peter Murray, Hyeoun-Ae Park, Christoph U Lehmann
INTRODUCTION: Official recognition and certification for informatics professionals are essential aspects of workforce development. OBJECTIVE: To describe the history, pathways, and nuances of certification in nursing informatics across the globe; compare and contrast those with board certification in clinical informatics for physicians. METHODS: (1) A review of the representative literature on informatics certification and related competencies for nurses and physicians, and relevant websites for nursing informatics associations and societies worldwide; (2) similarities and differences between certification processes for nurses and physicians, and (3) perspectives on roles for nursing informatics professionals in healthcare Results: The literature search for 'nursing informatics certification' yielded few results in PubMed; Google Scholar yielded a large number of citations that extended to magazines and other non-peer reviewed sources...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27830253/clinical-research-informatics-for-big-data-and-precision-medicine
#12
C Weng, M G Kahn
OBJECTIVES: To reflect on the notable events and significant developments in Clinical Research Informatics (CRI) in the year of 2015 and discuss near-term trends impacting CRI. METHODS: We selected key publications that highlight not only important recent advances in CRI but also notable events likely to have significant impact on CRI activities over the next few years or longer, and consulted the discussions in relevant scientific communities and an online living textbook for modern clinical trials...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27830249/efficient-results-in-semantic-interoperability-for-health-care-findings-from-the-section-on-knowledge-representation-and-management
#13
L F Soualmia, J Charlet
OBJECTIVES: To summarize excellent current research in the field of Knowledge Representation and Management (KRM) within the health and medical care domain. METHOD: We provide a synopsis of the 2016 IMIA selected articles as well as a related synthetic overview of the current and future field activities. A first step of the selection was performed through MEDLINE querying with a list of MeSH descriptors completed by a list of terms adapted to the KRM section. The second step of the selection was completed by the two section editors who separately evaluated the set of 1,432 articles...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27830246/the-unintended-consequences-of-health-information-technology-revisited
#14
E Coiera, J Ash, M Berg
INTRODUCTION: The introduction of health information technology into clinical settings is associated with unintended negative consequences, some with the potential to lead to error and patient harm. As adoption rates soar, the impact of these hazards will increase. OBJECTIVE: Over the last decade, unintended consequences have received great attention in the medical informatics literature, and this paper seeks to identify the major themes that have emerged. RESULTS: Rich typologies of the causes of unintended consequences have been developed, along with a number of explanatory frameworks based on socio-technical systems theory...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27830245/unintended-consequences-of-sensor-signal-and-imaging-informatics-new-problems-and-new-solutions
#15
C Hughes, S Voros, A Moreau-Gaudry
OBJECTIVES: This synopsis presents a selection for the IMIA (International Medical Informatics Association) Yearbook 2016 of excellent research in the broad field of Sensor, Signal and Imaging Informatics published in the year 2015, with a focus on Unintended consequences: new problems and new solutions. METHODS: We performed a systematic initial selection and a double blind peer review process to find the best papers in this domain published in 2015, from the PubMed and Web of Science databases...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27830243/new-problems-new-solutions-a-never-ending-story-findings-from-the-clinical-information-systems-perspective-for-2015
#16
W O Hackl, T Ganslandt
OBJECTIVE: To summarize recent research and to propose a selection of best papers published in 2015 in the field of Clinical Information Systems (CIS). METHOD: The query which had been used last year to retrieve articles for the CIS section of the IMIA Yearbook of Medical Informatics 2015 was refined. It again aimed at identifying relevant publications in the field of CIS and comprised search terms from the Medical Subject Headings (MeSH) catalog as well as additional free text search terms from PubMed and Web of Science...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27830242/building-a-privacy-ethics-and-data-access-framework-for-real-world-computerised-medical-record-system-data-a-delphi-study-contribution-of-the-primary-health-care-informatics-working-group
#17
H Liyanage, S-T Liaw, C T Di Iorio, C Kuziemsky, R Schreiber, A L Terry, S de Lusignan
BACKGROUND: Privacy, ethics, and data access issues pose significant challenges to the timely delivery of health research. Whilst the fundamental drivers to ensure that data access is ethical and satisfies privacy requirements are similar, they are often dealt with in varying ways by different approval processes. OBJECTIVE: To achieve a consensus across an international panel of health care and informatics professionals on an integrated set of privacy and ethics principles that could accelerate health data access in data-driven health research projects...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27830240/human-factors-and-organizational-issues-in-2015-the-increasing-complexity-of-the-healthcare-domain-calls-for-more-comprehensive-approaches
#18
S Pelayo, R Santos
OBJECTIVE: To summarize significant research contributions on human factors and organizational issues in medical informatics published in 2015. METHODS: An extensive search using PubMed/Medline and Web of Science® was conducted to identify the scientific contributions published in 2015 that address human factors and organizational issues in medical informatics. The selection process comprised three steps: (i) 15 candidate best papers were first selected by the two section editors, (ii) external reviewers from internationally renowned research teams reviewed each candidate best paper, and (iii) the final selection of five best papers was conducted by the editorial board of the Yearbook...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27830235/unintended-consequences-new-problems-new-solutions-contributions-from-2015
#19
R Koppel, Y Chen
OBJECTIVE: To select the best of the 2015 published papers on unintended consequences of healthcare information technology (HIT). METHOD: Literature searches in several areas of scholarship, including IT, human factors, evaluation studies, medical errors, medical informatics, and implementation science. Also, because the specific terms "unintended consequences" were not often included in abstracts and titles, a more nuanced search algorithm was developed. RESULTS: We identified 754 papers that had some empirical research on unintended consequences of HIT...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27830225/troubled-waters-navigating-unintended-consequences-of-health-information-technology
#20
C U Lehmann, B Séroussi, M-C Jaulent
OBJECTIVES: To provide an introduction to the 2016 IMIA Yearbook of Medical Informatics by the editors. METHODS: We present a brief overview of the 2016 special topic "Unintended consequences of Health IT: new problems, new solutions", we review our choice of special topic section editors, and discuss the transitions in the editorial team for next year. RESULTS: This edition of the Yearbook acknowledges the fact that implementation and use of Health Information Technology (HIT) may result in unintended consequences, which may lead to both adverse and sometimes beneficial outcomes...
November 10, 2016: Yearbook of Medical Informatics
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