Sandra Michaela Ihne-Schubert, Oliver Goetze, Felix Gerstendörfer, Floran Sahiti, Ina Schade, Aikaterini Papagianni, Caroline Morbach, Stefan Frantz, Hermann Einsele, Stefan Knop, Claudia Sommer, Beat Müllhaupt, Torben Schubert, Stefan Störk, Andreas Geier
Background: Congestion is associated with poor prognosis in cardiac amyloidosis (CA). The cardio-hepatic interaction and the prognostic impact of secondary liver affection by cardiac congestion in CA are poorly understood and require further characterisation. Methods: Participants of the amyloidosis cohort study AmyKoS at the Interdisciplinary Amyloidosis Centre of Northern Bavaria with proven transthyretin (ATTR-CA) and light chain CA (AL-CA) underwent serial work-up including laboratory tests, echocardiography, and in-depth hepatic assessment by vibration-controlled transient elastography (VCTE) and 13 C-methacetin breath test...
March 1, 2024: Journal of Clinical Medicine