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https://www.readbyqxmd.com/read/29350882/cardiac-function-by-three-dimensional-speckle-tracking-imaging-and-cytokines-in-kawasaki-disease
#1
Masataka Kato, Mamoru Ayusawa, Hirofumi Watanabe, Akiko Komori, Yuriko Abe, Takahiro Nakamura, Hiroshi Kamiyama, Shori Takahashi
BACKGROUND: IT is well known that serum N-terminal pro brain natriuretic peptide (NT-proBNP) tends to elevate in acute phase of Kawasaki disease (KD), but the cause of NT-proBNP elevation has not been clarified. Our previous study revealed that cardiac function evaluated by two-dimensional echocardiography (2D-E) such as ejection fraction (EF) was normal. However, cardiac function evaluated by 2D-E does not reflect subtle change of cardiac dysfunction and the relation has still been controversial...
January 19, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29345112/low-nt-probnp-levels-in-overweight-and-obese-patients-do-not-rule-out-a-diagnosis-of-heart-failure-with-preserved-ejection-fraction
#2
Leo F Buckley, Justin M Canada, Marco G Del Buono, Salvatore Carbone, Cory R Trankle, Hayley Billingsley, Dinesh Kadariya, Ross Arena, Benjamin W Van Tassell, Antonio Abbate
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome that presents clinicians with a diagnostic challenge. The use of natriuretic peptides to exclude a diagnosis of HFpEF has been proposed. We sought to compare HFpEF patients with N-terminal pro-brain natriuretic peptide (NT-proBNP) level above and below the proposed cut-off. METHODS: Stable patients (n = 30) with left ventricular (LV) ejection fraction ≥ 50% were eligible if they had a diagnosis of HF according to the European Society of Cardiology diagnostic criteria...
January 18, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29344375/elevated-serum-levels-of-cardiovascular-biomarkers-are-associated-with-progression-of-renal-cancer
#3
Takao Kamai, Yuumi Tokura, Toshitaka Uematsu, Kazumasa Sakamoto, Issei Suzuki, Kohei Takei, Takahiro Narimatsu, Tsunehito Kambara, Hideo Yuki, Hironori Betsunoh, Hideyuki Abe, Yoshitatsu Fukabori, Masahiro Yashi, Ken-Ichiro Yoshida
Objective: Renal cell carcinoma (RCC) is a hypervascular tumour due to high constitutive production of vascular endothelial growth factor (VEGF), which is activated by hypoxia-inducible factor (HIF). Elevated levels of cardiovascular peptides, including brain natriuretic peptide (BNP), have been reported in patients with cancer, regardless of whether they have overt cardiovascular disease. Furthermore, it has been demonstrated that hypoxia stimulates BNP production by an HIF-dependent manner...
2018: Open Heart
https://www.readbyqxmd.com/read/29338917/exercise-training-in-adults-with-repaired-tetralogy-of-fallot-a-randomized-controlled-pilot-study-of-continuous-versus-interval-training
#4
Marko Novaković, Katja Prokšelj, Uroš Rajkovič, Tjaša Vižintin Cuderman, Katja Janša Trontelj, Zlatko Fras, Borut Jug
INTRODUCTION: Adults with repaired tetralogy of Fallot (ToF) have impaired exercise capacity, vascular and cardiac autonomic function, and quality of life (QoL). Specific effects of high-intensity interval or moderate continuous exercise training on these parameters in adults with repaired ToF remain unknown. METHODS AND RESULTS: Thirty adults with repaired ToF were randomized to either high-intensity interval, moderate intensity continuous training (36 sessions, 2-3 times a week) or usual care (no supervised exercise)...
January 3, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29336389/a-randomized-controlled-trial-comparing-the-myocardial-protective-effects-of-isoflurane-with-propofol-in-patients-undergoing-elective-coronary-artery-bypass-surgery-on-cardiopulmonary-bypass-assessed-by-changes-in-n-terminal-brain-natriuretic-peptide
#5
Balaji Kuppuswamy, Kirubakaran Davis, Raj Sahajanandan, Manickam Ponniah
OBJECTIVE: The objective of the study is to compare the myocardial protective effects of isoflurane with propofol in patients undergoing elective coronary artery bypass surgery on cardiopulmonary bypass (CPB), the cardio protection been assessed by changes in N-terminal brain natriuretic peptide (NT proBNP). Methodology and Design: This study is designed as a participant blinded, prospective randomized clinical trial. SETTING: Christian Medical College Hospital, Vellore, India...
January 2018: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/29335079/-expression-of-plasma-mirna-497-in-children-with-sepsis-induced-myocardial-injury-and-its-clinical-significance
#6
Zhong-Jing Wu, Ya-Feng Chen, Hai-Dao Wang, Fang-Hong Gao
OBJECTIVE: To study the expression of plasma miRNA-497 in children with sepsis-induced myocardial injury and its clinical significance. METHODS: A total of 148 children with sepsis were enrolled. According to the presence or absence of myocardial injury, these children were divided into myocardial injury group (n=58) and non-myocardial injury group (n=90). The two groups were compared in terms of the changes in plasma levels of miRNA-497, cardiac troponin I (cTnI), creatine kinase-MB (CK-MB), N-terminal pro-brain natriuretic peptide (NT-proBNP), procalcitonin (PCT), and C-reactive protein (CRP) and left ventricular ejection fraction (LVEF)...
January 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29332544/the-possible-use-of-preoperative-natriuretic-peptides-for-discriminating-low-versus-moderate-high-surgical-risk-patient
#7
Luigi Vetrugno, Daniele Orso, Carola Matellon, Marilù Giaccalone, Tiziana Bove, Elena Bignami
Perioperative risk scores for patients undergoing noncardiac surgery are generally considered inaccurate, poor, or, at best, modest. We propose estimating a patient's pretest and posttest probability of cardiac morbidity and death using the preoperative scoring system plus the negative likelihood ratio from brain natriuretic peptide (BNP) or N-terminal proB-type natriuretic peptide (NT-proBNP) plasma levels. Our clinical challenge scenario showed a pretest probability of postoperative major cardiac complications with the patient risk factor as 6...
January 1, 2018: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29330256/osteoprotegerin-is-associated-with-major-bleeding-but-not-with-cardiovascular-outcomes-in-patients-with-acute-coronary-syndromes-insights-from-the-plato-platelet-inhibition-and-patient-outcomes-trial
#8
Thor Ueland, Axel Åkerblom, Tatevik Ghukasyan, Annika E Michelsen, Pål Aukrust, Richard C Becker, Maria Bertilsson, Anders Himmelmann, Stefan K James, Agneta Siegbahn, Robert F Storey, Frederic Kontny, Lars Wallentin
BACKGROUND: Elevated levels of osteoprotegerin, a secreted tumor necrosis factor-related molecule, might be associated with adverse outcomes in patients with coronary artery disease. We measured plasma osteoprotegerin concentrations on hospital admission, at discharge, and at 1 and 6 months after discharge in a predefined subset (n=5135) of patients with acute coronary syndromes in the PLATO (Platelet Inhibition and Patient Outcomes) trial. METHODS AND RESULTS: The associations between osteoprotegerin and the composite end point of cardiovascular death, nonprocedural spontaneous myocardial infarction or stroke, and non-coronary artery bypass grafting major bleeding during 1 year of follow-up were assessed by Cox proportional hazards models...
January 12, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29329761/n-terminal-pro-b-type-natriuretic-peptide-for-monitoring-after-balloon-pulmonary-angioplasty-for-chronic-thromboembolic-pulmonary-hypertension
#9
Steffen D Kriechbaum, Christoph B Wiedenroth, Jan Sebastian Wolter, Regula Hütz, Moritz Haas, Andreas Breithecker, Fritz C Roller, Till Keller, Stefan Guth, Andreas Rolf, Christian W Hamm, Eckhard Mayer, Christoph Liebetrau
BACKGROUND: Balloon pulmonary angioplasty (BPA) is an emerging interventional treatment option for chronic thromboembolic pulmonary hypertension (CTEPH). The non-invasive monitoring of CTEPH patients is a clinical challenge. In this study we examined changes in N-terminal pro-B-type natriuretic peptide (NT-proBNP) in patients undergoing BPA for inoperable CTEPH and related them to peri-procedural success. METHODS: In this study we analyzed a total of 51 consecutive patients who underwent BPA treatment and completed a 6-month follow-up (6-MFU) between March 2014 and March 2017...
December 8, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29328539/early-detection-of-myocardial-involvement-by-t1-mapping-of-cardiac-mri-in-idiopathic-inflammatory-myopathy
#10
Liuyu Yu, Jianhong Sun, Jiayu Sun, Jiangbo Li, Yang Dong, Xiaoyue Zhou, Andreas Greiser, Yuchi Han, Qing Zhang, Qibing Xie, Yucheng Chen
BACKGROUND: Polymyositis (PM) and dermatomyositis (DM) are common types of idiopathic inflammatory myopathy (IIM), wherein patients are prone to adverse cardiovascular events. PURPOSE: To explore the value of cardiac magnetic resonance imaging (MRI) for detecting cardiac involvement in PM/DM patients using a T1 mapping technique. STUDY TYPE: Prospective observational study. POPULATION: In all, 25 PM/DM patients free of cardiovascular symptoms and preserved ventricular systolic function and 25 healthy volunteers matched for age and sex served as controls...
January 12, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29327518/a-study-of-cardiovascular-abnormalities-in-hiv-positive-patients-in-a-tertiary-care-hospital-in-northern-india
#11
Shyam Chaudhary, Apurva, Kamal Kumar Sawlani, D Himanshu Reddy, Sharad Chandra Yadav, Munna Lal Patel, Anil Kumar Tripathi, Arvind Kumar Vaish
Introduction: Cardiovascular illness is common in patients with HIV infection, particularly in the later course of disease. Cardiovascular abnormalities in people living with HIV disease (PLHIV) often go unrecognized or untreated resulting in increased cardiovascular related morbidity and mortality and reduced quality of life. The prevalence of cardiac involvement in PLHIV has been reported to range between 28 to 73%. However, the incidence of symptomatic heart failure in HIV positive patients is 8-10%...
December 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29325363/-related-factors-for-the-development-of-fulminant-myocarditis-in-adults
#12
L J Sun, L J Guo, M Cui, Y Li, B D Zhou, J L Han, Z Zhang, Y Z Zhang, W Gao
Objective: To determine the early recognizable factors related to patients with fulminant myocarditis. Methods: Medical records from 60 adult patients who were diagnosed with acute viral myocarditis from January 2003 to September 2016 in our hospital were retrospectively reviewed, and divided into the fulminant group (n=9) and the non-fulminant group (n=51). Clinical presentations, biochemical markers, electrocardiography and echocardiography features on admission were analyzed. Results: Prevalence of syncope (33...
December 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29324263/the-role-of-pro-fibrotic-biomarkers-in-paroxysmal-and-persistent-atrial-fibrillation
#13
Adina Elena Stanciu, Radu Gabriel Vatasescu, Marcel Marian Stanciu, Nafija Serdarevic, Maria Dorobantu
PURPOSE: Signaling pathways involved in electrical, structural and contractile remodeling processes behind development and progression of atrial fibrillation (AF) have not been completely elucidated, but it seems to be related to complex interactions among neurohormonal and cellular mediators. We aimed to investigate interleukin-6 (IL-6), transforming growth factor-beta1 (TGF-β1), matrix metalloproteinase-9 (MMP-9), tissue inhibitor of metalloproteinase-1 (TIMP-1), as biomarkers of atrial remodeling, in patients with paroxysmal and persistent AF, and their correlation with N-terminal prohormone of brain natriuretic peptide (NT-proBNP) and left atrial (LA) diameter...
January 8, 2018: Cytokine
https://www.readbyqxmd.com/read/29321804/the-relationship-between-nt-probnp-and-depression-in-patients-with-heart-failure
#14
Ying-Hui Gao, Lin Liu
No abstract text is available yet for this article.
November 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29317115/post-procedural-n-terminal-pro-brain-natriuretic-peptide-predicts-one-year-mortality-after-transcatheter-aortic-valve-implantation
#15
Nelson Carlos Vale, Rui Campante Teles, Sérgio Madeira, João Brito, Manuel Sousa Almeida, Tiago Nolasco, Joao Abecasis, Gustavo Rodrigues, João Carmo, Maria Furstenau, Regina Ribeiras, José Pedro Neves, Miguel Mendes
INTRODUCTION: Natriuretic peptides are ubiquitously used for diagnosis, follow-up and prognostic assessment in various heart conditions. N-terminal pro-brain natriuretic peptide (NT-proBNP) correlates with aortic stenosis severity, however its significance after transcatheter aortic valve implantation (TAVI) is not well established. AIM: We aimed to assess the prognostic value of NT-proBNP at one year in patients undergoing TAVI. METHODS: This single-center retrospective analysis included 151 patients in whom both baseline and one-month post-procedure NT-proBNP were measured, from 206 consecutive patients undergoing TAVI between November 2008 and December 2014...
January 6, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29314721/peritoneal-protein-losses-depend-on-more-than-just-peritoneal-dialysis-modality-and-peritoneal-membrane-transporter-status
#16
Suree Yoowannakul, Lauren S Harris, Andrew Davenport
Peritoneal protein clearance (PPCl) depends upon vascular supply and size selective permeability. Some previous reports suggested PPCl can distinguish fast peritoneal membrane transport due to local or systemic inflammation. However, as studies have been discordant, we wished to determine factors associated with an increased PPCl. Consecutive patients starting peritoneal dialysis (PD) who were peritonitis-free were studied. Data included a baseline peritoneal equilibration test (PET), measurement of dialysis adequacy, 24-h dialysate PPCl and body composition measured by multifrequency bioimpedance...
January 4, 2018: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/29310645/effects-of-6-month-treatment-with-the-glucagon-like-peptide-1-analogue-liraglutide-on-arterial-stiffness-left-ventricular-myocardial-deformation-and-oxidative-stress-in-subjects-with-newly-diagnosed-type-2-diabetes
#17
Vaia Lambadiari, George Pavlidis, Foteini Kousathana, Maria Varoudi, Dimitrios Vlastos, Eirini Maratou, Dimitrios Georgiou, Ioanna Andreadou, John Parissis, Helen Triantafyllidi, John Lekakis, Efstathios Iliodromitis, George Dimitriadis, Ignatios Ikonomidis
BACKGROUND: Incretin-based therapies are used in the treatment of type 2 diabetes mellitus (T2DM) and obesity. We investigated the changes in arterial stiffness and left ventricular (LV) myocardial deformation after 6-month treatment with the GLP-1 analogue liraglutide in subjects with newly diagnosed T2DM. METHODS: We randomized 60 patients with newly diagnosed and treatment-naive T2DM to receive either liraglutide (n = 30) or metformin (n = 30) for 6 months...
January 8, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29306896/serum-conjugated-linoleic-acid-and-risk-of-incident-heart-failure-in-older-men-the-british-regional-heart-study
#18
S Goya Wannamethee, Barbara J Jefferis, Lucy Lennon, Olia Papacosta, Peter H Whincup, Aroon D Hingorani
BACKGROUND: Evidence largely from animal studies suggests that conjugated linoleic acid (CLA) may have cardiovascular health benefits. However, few prospective studies have examined the association between CLA and cardiovascular disease. We have prospectively examined the association between serum CLA and incident coronary heart disease and heart failure (HF) in older men. METHODS AND RESULTS: Prospective study of 3806 men, aged 60 to 79 years, without prevalent HF followed up for an average of 13 years, during which there were 295 incident HF cases...
January 6, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29305104/heart-failure-with-mid-range-ejection-fraction-in-patients-admitted-to-internal-medicine-departments-findings-from-the-rica-registry
#19
María Esther Guisado-Espartero, Prado Salamanca-Bautista, Óscar Aramburu-Bodas, Alicia Conde-Martel, José Luis Arias-Jiménez, Pau Llàcer-Iborra, Melitón Francisco Dávila-Ramos, Yolanda Cabanes-Hernández, Luis Manzano, Manuel Montero-Pérez-Barquero
AIM: To improve the knowledge on characteristics, treatment and prognosis in patients with heart failure (HF) and mid-range ejection fraction discharged after an acute HF episode. METHODS: We prospectively included and followed 2753 patients admitted with HF to Internal Medicine units. Patients were classified according to ejection fraction (EF) into three strata: reduced, EF <40% (HFrEF); mid-range EF 40-49% (HFmrEF); and preserved EF ≥50% (HFpEF). Clinical, echocardiographic, laboratory data and treatment at discharge were recorded and the groups were compared...
January 2, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29304158/hospitalization-and-medical-cost-of-patients-with-elevated-serum-n-terminal-pro-brain-natriuretic-peptide-levels
#20
Toshiro Kitagawa, Noboru Oda, Mariko Mizukawa, Takayuki Hidaka, Makiko Naka, Susumu Nakayama, Yasuki Kihara
BACKGROUND: Patients with heart failure (HF) are reportedly at high risk for 'all-cause' re-hospitalization. A biomarker for HF, N-terminal pro-brain natriuretic peptide (NT-proBNP), enables to simply detect patients with possible HF (pHF). We examined the hospitalization and medical cost of Japanese patients detected by an elevated serum NT-proBNP, and also evaluated the effects of institutional team approaches for HF on their all-cause hospitalizations. METHODS: We retrospectively extracted all adult patients with serum NT-proBNP ≥400 pg/ml measured between January and March 2012 in Hiroshima University Hospital as pHF-positive patients...
2018: PloS One
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