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https://www.readbyqxmd.com/read/28108966/breast-reconstruction-and-postmastectomy-radiotherapy-complications-by-type-and-timing-and-other-problems-in-radiation-oncology
#1
Kenji Sekiguchi, Jiro Kawamori, Hideko Yamauchi
Breast reconstruction (BR) represents a suitable option for women who are not expected to require postmastectomy radiotherapy (PMRT). As recent evidence has led to an extension of the indications for PMRT, this has also appeared to increase the incidence of reconstructive complications. Nevertheless, in the USA at least, trends towards BR are changing. The frequency of immediate reconstruction continues to increase, even in the setting of PMRT. In immediate implant-based reconstruction, a staged approach is preferred...
January 20, 2017: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/28108811/who-really-wins-efficacy-of-a-croatian-youth-gambling-prevention-program
#2
Aleksandra Huic, Valentina Kranzelic, Dora Dodig Hundric, Neven Ricijas
This paper reports on the development and pilot evaluation of a Croatian school-based youth gambling prevention program "Who really wins?". The program is aimed at minimizing risk and enhancing protective factors related to youth gambling. A short-term evaluation of the program was conducted with a sample of 190 first and second year high-school students (67.6% boys, aged 14-17 years; average age 15.61). An experimental design with two groups (Training vs. No Training) and two measurement sessions (pre-test and post-test sessions) was used to evaluate change in problem gambling awareness, cognitive distortions, knowledge of the nature of random events as well as in social skills...
January 20, 2017: Journal of Gambling Studies
https://www.readbyqxmd.com/read/28108115/a-reappraisal-of-the-surgical-planning-of-the-superficial-circumflex-iliac-artery-perforator-flap
#3
Shaoqing Feng, Wenjing Xi, Zheng Zhang, Mathias Tremp, Dirk J Schaefer, Parviz L Sadigh, Wenjie Zhang, Yi Xin Zhang
OBJECTIVE: The popularity of the superficial circumflex iliac artery perforator (SCIP) flap has been limited by factors such as variable vascular anatomy and short arterial pedicle. This article aimed to delineate flap design and harvest strategies based around either the proximal or distal perforators of the superficial circumflex iliac artery (SCIA) and propose a set of strategies that can help deal with the limitations of the flap. METHOD: From August 2011 to June 2015, the SCIP flap was used in 80 patients for soft tissue defects at our institution...
December 22, 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28107906/development-of-data-independent-acquisition-workflows-for-metabolomic-analysis-on-a-quadrupole-orbitrap-platform
#4
Juntuo Zhou, Yuhua Li, Xi Chen, Lijun Zhong, Yuxin Yin
Untargeted metabolomic profiling has been widely used in recent years. However, the low reproducibility of the data-dependent acquisition (DDA) strategy presents a major bottleneck that considerably limits the reliability of metabolomic studies in biological and clinical research. The data-independent acquisition (DIA) strategy is proposed to solve the above-mentioned problem, and it is gaining popularity. This paper presents a novel approach for performing metabolomic analysis using an untargeted, liquid chromatography-data independent-mass spectrometry (LC-DIA-MS) strategy on a quadrupole-Orbitrap platform...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107468/micro-x-ray-computed-tomography-mass-loss-assessment-of-different-uhmwpe-a-hip-joint-simulator-study-on-standard-vs-cross-linked-polyethylene
#5
Saverio Affatato, Filippo Zanini, Simone Carmignato
More than 60.000 hip arthroplasty are performed every year in Italy. Although Ultra-High-Molecular-Weight-Polyethylene remains the most used material as acetabular cup, wear of this material induces over time in vivo a foreign-body response and consequently osteolysis, pain, and the need of implant revision. Furthermore, oxidative wear of the polyethylene provoke several and severe failures. To solve these problems, highly cross-linked polyethylene and Vitamin-E-stabilized polyethylene were introduced in the last years...
2017: PloS One
https://www.readbyqxmd.com/read/28106803/opportunistic-capacity-based-resource-allocation-for-chunk-based-multi-carrier-cognitive-radio-sensor-networks
#6
Jie Huang, Xiaoping Zeng, Xin Jian, Xiaoheng Tan, Qi Zhang
The spectrum allocation for cognitive radio sensor networks (CRSNs) has received considerable research attention under the assumption that the spectrum environment is static. However, in practice, the spectrum environment varies over time due to primary user/secondary user (PU/SU) activity and mobility, resulting in time-varied spectrum resources. This paper studies resource allocation for chunk-based multi-carrier CRSNs with time-varied spectrum resources. We present a novel opportunistic capacity model through a continuous time semi-Markov chain (CTSMC) to describe the time-varied spectrum resources of chunks and, based on this, a joint power and chunk allocation model by considering the opportunistically available capacity of chunks is proposed...
January 18, 2017: Sensors
https://www.readbyqxmd.com/read/28106587/the-roles-and-functions-of-informatics-nurse-specialists-in-taiwan
#7
Tso Ying Lee
During the modernization process in hospitals, information technology is an important indicator. "Informatics nurses" play a critical role in hospitals and clinics. In Taiwan, the certification system of informatics nurses just recently began in 2016. The development of certificated personnel results from students who have graduated with a university degree in nursing and have taken classes in informatics, as well as nurses who have been trained in informatics at clinics and hospitals, and the establishment of a national nursing informatics association...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28106446/exacerbating-the-cosmological-constant-problem-with-interacting-dark-energy-models
#8
M C David Marsh
Future cosmological surveys will probe the expansion history of the Universe and constrain phenomenological models of dark energy. Such models do not address the fine-tuning problem of the vacuum energy, i.e., the cosmological constant problem (CCP), but can make it spectacularly worse. We show that this is the case for "interacting dark energy" models in which the masses of the dark matter states depend on the dark energy sector. If realized in nature, these models have far-reaching implications for proposed solutions to the CCP that require the number of vacua to exceed the fine-tuning of the vacuum energy density...
January 6, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28105596/monitoring-nutrients-fate-after-digestate-spreading-in-a-short-rotation-buffer-area
#9
Nicolò Colombani, Bruno Boz, Bruna Gumiero, Micòl Mastrocicco
One of the main sources of reactive nitrogen pollution is animal manure. The disposal of digestate (material remaining after the anaerobic digestion of a biodegradable feedstock) in agricultural soils could solve both the problems of soil fertilization and waste removal, but the fate of digestate in the environment must be assessed carefully before its massive utilization. To investigate whether digestate could be safely employed as a soil fertilizer, an agricultural field located in Monastier di Treviso (Northern Italy) and characterized by the presence of low hydraulic conductivity clay soils, was selected to be amended with bovine digestate...
January 20, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28105531/-big-eye-surgery-the-ethics-of-medicalizing-asian-features
#10
Yves Saint James Aquino
The popularity of surgical modifications of race-typical features among Asian women has generated debates on the ethical implications of the practice. Focusing on blepharoplasty as a representative racial surgery, this article frames the ethical discussion by viewing Asian cosmetic surgery as an example of medicalization, which can be interpreted in two forms: treatment versus enhancement. In the treatment form, medicalization occurs by considering cosmetic surgery as remedy for pathologized Asian features; the pathologization usually occurs in reference to western features as the norm...
January 19, 2017: Theoretical Medicine and Bioethics
https://www.readbyqxmd.com/read/28105501/-diagnostics-and-multimodal-treatment-of-depression-in-old-age-new-developments
#11
Gerhard W Eschweiler
Depressive disorders in elderly persons are frequent and can either first be manifested at a younger age and show a recurrent pattern during later life (ICD 10, F33.*) or have an onset beyond 60 years, which is termed late onset depression (LOD). This LOD has a higher tendency to chronification and implies an increased risk of progression, especially to vascular dementia. The multifactorial genesis of depression in old age includes psychosocial, vascular and metabolic factors and requires multimodal therapy modules at the biological and psychosocial level, which is now increasingly being empirically proven...
January 19, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28105196/nanotechnology-for-multimodality-treatment-of-cancer
#12
Xiao-Ying Zhang, Pei-Ying Zhang
Nanotechnology is the latest evolving field and its applications in medicine in recent decades has shown great potential. It has also given a new face to the therapeutics against cancer in recent years. The electronic databases of MEDLINE, EMBASE and PubMed were searched for recent studies, reporting the importance of nanomedicine. The concluding remarks of the above papers mostly confirmed the growing potential of nanomedicine, particularly in the field of cancer. Furthermore, nanomedicine has been observed to promote the therapeutic effect of agents by formulating them into nanocarriers...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28104618/hysa-a-hybrid-structural-variant-assembly-approach-using-next-generation-and-single-molecule-sequencing-technologies
#13
Xian Fan, Mark Chaisson, Luay Nakhleh, Ken Chen
Achieving complete, accurate and cost-effective assembly of human genomes is of great importance for realizing the promise of precision medicine. The abundance of repeats and genetic variations in human genomes and the limitations of existing sequencing technologies call for the development of novel assembly methods that can leverage the complementary strengths of multiple technologies. We propose a hybrid structural variant assembly (HySA) approach that integrates sequencing reads from next-generation sequencing and single-molecule sequencing technologies to accurately assemble and detect structural variations in human genomes...
January 19, 2017: Genome Research
https://www.readbyqxmd.com/read/28104562/assessing-patient-rated-vs-clinician-rated-adherence-to-the-therapy-in-treatment-resistant-schizophrenia-schizophrenia-responders-and-non-schizophrenia-patients
#14
Felice Iasevoli, Andrea Fagiolini, Maria Vittoria Formato, Emiliano Prinzivalli, Sara Giordano, Raffaele Balletta, Vincenzo De Luca, Andrea de Bartolomeis
The present study evaluated consistency, reliability, and determinants of two real-world measures of adherence to prescription in 57 schizophrenia and 61 non-schizophrenia patients. Treatment resistant schizophrenia (TRS) was additionally diagnosed in 28 of the schizophrenia patients. Patients were screened for clinical severity, cognitive functioning, and adherence by 10-item Drug Attitude Inventory (DAI-10) or Adherence-to-Therapy (AtT), a clinician-rated tool developed by our group. DAI-10 and AtT scores showed a significant correlation (p=0...
January 7, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28104550/robust-estimation-of-carotid-artery-wall-motion-using-the-elasticity-based-state-space-approach
#15
Zhifan Gao, Huahua Xiong, Xin Liu, Heye Zhang, Dhanjoo Ghista, Wanqing Wu, Shuo Li
The dynamics of the carotid artery wall has been recognized as a valuable indicator to evaluate the status of atherosclerotic disease in the preclinical stage. However, it is still a challenge to accurately measure this dynamics from ultrasound images. This paper aims at developing an elasticity-based state-space approach for accurately measuring the two-dimensional motion of the carotid artery wall from the ultrasound imaging sequences. In our approach, we have employed a linear elasticity model of the carotid artery wall, and converted it into the state space equation...
January 10, 2017: Medical Image Analysis
https://www.readbyqxmd.com/read/28103992/-advances-in-the-research-of-three-dimensional-skin-printing
#16
J J Sheng, G C Liu, H H Li, S H Zhu
As a new technology, three-dimensional printing possesses the characteristics of high precision and strong controllability, which has become a new technology and can be used in tissue engineering. Currently, using three-dimensional printing to build artificial skin has made certain achievement, and experiments in vitro have confirmed that the three-dimensional printing has the possibilities to build artificial skin whose structure and function are close to those of nature skin. However, the technology is not yet very mature and there are still some problems need to be solved, such as the recreation of the cutaneous appendages and the degradation and absorption of the extracellular matrix...
January 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28103988/-to-enhance-study-on-translation-and-application-of-mesenchymal-stem-cells-in-wound-repair
#17
D H Hu, W Zhang
Wound repair is a complicated process of interactions among numerous types of cells, involving the activation of multiple cells and various cytokines. The extensive burn and chronic wound are already big challenges for clinic due to the limitations of existing treatment means. Stem cell technology, as a new therapy, may be the optimum choice for wound repair. Mesenchymal stem cells are multipotent cells with self-renewal and differentiation capacity and have a broad tissue distribution, which are promising in treating wound, and it is worthy to discuss and analyze their role, clinical translation and application in wound repair, the facing problems at present and solving strategies as well...
January 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28103721/evidence-based-medicine-ebm-for-undergraduate-medical-students-a-six-step-integrative-approach
#18
Hani Atwa, Adel Abdelaziz
BACKGROUND: Nowadays, there is an increasing interest in practicing evidence-based medicine (EBM) to provide valid and up-to-date information about health problems and procedures for solving these problems. However, studying EBM among other medical education disciplines remains unsatisfactory. AIM: To design and pilot a basic course on EBM for undergraduate medical students in order to raise the awareness of the Saudi medical education community about this discipline...
January 20, 2017: Medical Teacher
https://www.readbyqxmd.com/read/28103557/data-dependent-label-distribution-learning-for-age-estimation
#19
Zhouzhou He, Xi Li, Zhongfei Zhang, Fei Wu, Xin Geng, Yaqing Zhang, Ming-Hsuan Yang, Yueting Zhuang
As an important and challenging problem in computer vision, face age estimation is typically cast as a classification or regression problem over a set of face samples with respect to several ordinal age labels, which have intrinsically cross-age correlations across adjacent age dimensions. As a result, such correlations usually lead to the age label ambiguities of the face samples. Namely, each face sample is associated with a latent label distribution that encodes the cross-age correlation information on label ambiguities...
January 18, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28103412/what-determines-posttraumatic-stress-and-growth-following-various-traumatic-events-a-study-in-a-turkish-community-sample
#20
Ervin Gul, A Nuray Karanci
This study aimed to examine the roles of personality traits, traumatic event types, coping, rumination, and social support in explaining posttraumatic stress symptoms (PTS) and posttraumatic growth (PTG) in a representative community sample of 498 Turkish adults. The results of 2 multiple regression analyses showed that PTS was associated with neuroticism, experiencing events involving intentional/assaultive violence, intrusive and deliberate rumination, and fatalistic coping. In contrast, PTG was related to conscientiousness, openness to experience, injury/shocking and sudden-death type of events, deliberate rumination, problem-solving coping, and perceived social support...
January 19, 2017: Journal of Traumatic Stress
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