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https://www.readbyqxmd.com/read/29777279/-flap-coverage-using-the-posterior-gluteal-thigh-flap
#1
REVIEW
M K Boyce, T R Mett, R Ipaktchi, P M Vogt
OBJECTIVE: Defect coverage of the sacral, trochanteric or ischial region with durable tissue (gluteal thigh flap). INDICATIONS: Decubital ulcers of the sacral, trochanteric or ischial region after exhaustion of conservative measures. CONTRAINDICATIONS: Moribund or palliative patients who do not benefit from defect coverage and are likely to suffer a life-threatening complication. Noncompliant patients, who cannot follow the postoperative recommendations or protocols in regard to positioning or recurrence prevention...
May 17, 2018: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/29776724/outcomes-of-splinting-in-pediatric-mallet-finger
#2
James S Lin, Julie Balch Samora
PURPOSE: Excessive flexion at the distal interphalangeal (DIP) joint disrupts the extensor mechanism, leading to mallet finger injuries. The goal of management is to restore active DIP joint extension. We sought to learn which variables (treatment technique, injury type, time to presentation, adherence to treatment) affect clinical outcomes of pediatric mallet finger injuries. METHODS: A retrospective review was performed of patients who presented with mallet finger injuries during 2013 to 2017 at a large pediatric hospital...
May 15, 2018: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29774772/assessing-the-quality-and-performance-of-human-research-protection-programs-to-guide-compliance-oversight-activities
#3
Min-Fu Tsan, Yen Nguyen
Routine on-site reviews should focus primarily on facilities that are at risk of harming human subjects. Using human research protection program performance metric data from 107 facilities, we defined a facility to be at risk when one of its noncompliance/incident rates was among the top three highest rates of that performance metric. Based on 14 performance metrics with noncompliance and incidents in 2017, 27 facilities were identified to be at risk. These 27 facilities at risk, while constituting only 25% of all facilities, contributed to 70% ± 25% ( M ± SD; range = 32%-100%) of all reported noncompliance/incidents...
May 1, 2018: Journal of Empirical Research on Human Research Ethics: JERHRE
https://www.readbyqxmd.com/read/29768316/evaluation-of-compliance-with-a-weight-based-nurse-driven-heparin-nomogram-in-a-tertiary-academic-medical-center
#4
James W Schurr, Craig A Stevens, Anne Bane, Sarah E Culbreth, Amy Leigh Miller, Jean M Connors, Katelyn W Sylvester
BACKGROUND: Recently, our institution adopted a weight-based nurse-driven heparin titration protocol that relies on nurses ordering laboratories, adjusting doses, and initiating boluses. Numerous institutions have implemented similar protocols with reported success. METHODS: A single-center retrospective analysis was conducted at the Brigham and Women's Hospital in Boston, Massachusetts that included all patients who were initiated on the weight-based nurse-driven heparin nomogram during a 30-day period...
June 2018: Critical Pathways in Cardiology
https://www.readbyqxmd.com/read/29763963/medication-tradeoffs-not-all-noncompliance-is-what-it-seems
#5
Greg J McKenna
Admit it. More than once, you've scanned a transplant journal, searching for a novel topic, something different from the many ubiquitous registry reviews. You hope you can find something topical, relevant for your patients and timely to current events. You probably didn't even realize this issue of Transplant International would be the one containing that very tropical, relevant and timely manuscript. This article is protected by copyright. All rights reserved.
May 15, 2018: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29760183/neural-mechanisms-underlying-individual-differences-in-control-averse-behavior
#6
Sarah Rudorf, Katrin Schmelz, Thomas Baumgartner, Roland Wiest, Urs Fischbacher, Daria Knoch
When another person tries to control one's decisions, some people might comply, but many will feel the urge to act against that control. This control aversion can lead to suboptimal decisions and it affects social interactions in many societal domains. To date, however, it has been unclear what drives individual differences in control-averse behavior. Here, we address this issue by measuring brain activity with fMRI while healthy female and male human participants make choices that are either free or controlled by another person, with real consequences to both interaction partners...
May 14, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29759266/drug-induced-insomnia-and-excessive-sleepiness
#7
REVIEW
Ann Van Gastel
Psychotropic and nonpsychotropic drugs, which may induce or aggravate insomnia and/or daytime sleepiness, are discussed. These central nervous system effects are possible from the interactions of a drug with any of the many neurotransmitters or receptors that are involved in sleep and wakefulness. Multiple interactions between disease, sleep, comorbid sleep disorders, and direct or indirect influences of pharmacologic agents are possible. Awareness of these effects is important to adapt treatment and reach optimal results for every patient...
June 2018: Sleep Medicine Clinics
https://www.readbyqxmd.com/read/29757101/identifying-and-predicting-profiles-of-medical-noncompliance-pediatric-caregivers-antibiotic-stewardship
#8
Rachel A Smith, Youllee Kim, Nkuchia M M'Ikanatha
Sometimes compliance with medical recommendations is problematic. We investigated pediatric caregivers' (N = 606) patterns of noncompliance with antibiotic stewardship based on the obstacle hypothesis. We tested predictors of noncompliance framed by the obstacle hypothesis, dissonance theory, and psychological reactance. The results revealed four profiles of caregivers' stewardship: one marked by compliance (Stewards) and three marked by types of noncompliance (Stockers, Persuaders, and Dissenters). The covariate analysis showed that, although psychological reactance predicted being noncompliant, it was types of obstacles and discrepant experiences that predicted caregivers' patterns of noncompliance with antibiotic stewardship...
May 14, 2018: Journal of Health Communication
https://www.readbyqxmd.com/read/29752000/noncompliance-of-patients-with-driving-restrictions-due-to-uncontrolled-epilepsy
#9
Laurent M Willems, Philipp S Reif, Susanne Knake, Hajo M Hamer, Constantin Willems, Günter Krämer, Felix Rosenow, Adam Strzelczyk
Epilepsies are a common and chronic neurological disorder characterized by sustained risk of recurrent seizures. Because of paroxysmal and often unpredictable occurrence of seizures, patients with uncontrolled epilepsy are subject to disease-specific restrictions in daily life, such as their career choice or specific work limitations. According to German law and many other European and international guidelines, driving is strictly prohibited in patients with uncontrolled epilepsy so as to increase active and passive safety in public road traffic...
May 9, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29737368/-minimally-invasive-correction-of-lesser-toe-deformities-and-treatment-of-metatarsalgia
#10
REVIEW
M Thomas, M Jordan
OBJECTIVE: Atraumatic and joint-sparing procedure for the correction of lesser toe deformities by using a linear or perpendicular osteotomy of the proximal and/or middle phalanx of the lesser toes with additional capsulotomies or tendon dissection for soft tissue realignment. Metatarsalgia is addressed via an extracapsular distal metaphyseal crescentic-like metatarsal osteotomy. INDICATIONS: Symptomatic lesser toe deformities, painful pseudoexostosis, metatarsalgia, symptomatic metatarsal malalignment, metatarsus adductus...
May 8, 2018: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/29736086/response-to-issues-concerning-the-article-treatment-compliance-and-noncompliance-in-psychoses
#11
K Nagaraja Rao
No abstract text is available yet for this article.
January 2018: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/29736070/understanding-masked-depression-a-clinical-scenario
#12
Prasad Shetty, Akshata Mane, Sourabh Fulmali, Ganesh Uchit
Background: Masked depression is often misdiagnosed due to the predominance of somatic symptoms and is further complicated by lack of awareness among doctors. Aim: The present survey was conducted to gather the views of psychiatrists and nonpsychiatrists regarding presentation and management aspects of masked depression. This may help in unmasking this condition and facilitate early identification and appropriate management of patients presenting with this condition...
January 2018: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/29734269/improving-patient-compliance-with-mechanical-venous-thromboembolism-prophylaxis
#13
Deepti Nahar, Aaron Nizam, Monique Farrow, Andrea Restifo, Michael Nimaroff
Venous thromboembolic events (VTE) occurring in the postoperative period are serious yet preventable conditions. Multiple studies have demonstrated that the risk of postoperative VTE can be successfully reduced with mechanical prophylaxis and/or chemoprophylaxis. Patients are often noncompliant with mechanical prophylaxis in the postoperative period. We performed a prospective nonrandomized controlled study to determine if providing an educational pamphlet would increase knowledge and compliance with mechanical VTE prophylaxis...
May 2018: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
https://www.readbyqxmd.com/read/29730590/the-use-of-administrative-sanctions-to-prevent-environmental-damage-in-impact-assessment-follow-ups
#14
Luiz Carlos Garcia, Alberto Fonseca
Scholars have long been highlighting the value of administrative sanctions in improving environmental policy enforcement. However, few studies have evaluated how such sanctions are implemented, particularly in the context of environmental impact assessments (EIA) and their respective follow-up programs. The main objective of this article was to evaluate how administrative sanctions have been used in EIA follow-ups, using the Brazilian state of Minas Gerais as the empirical context. More specifically it tried to understand what have been the main triggers, frequency, nature and financial values of the sanctions issued to noncompliant mining projects operating under the conditions of environmental licenses...
May 3, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29719370/evaluation-of-physician-prescribing-patterns-for-antibiotics-in-the-treatment-of-nonnecrotizing-skin-and-soft-tissue-infections
#15
Michael C Ezebuenyi, Fatima Brakta, Ifeanyichukwu O Onor, Daniel F Sarpong, Kendrea Bryant-Burks, Julio E Figueroa
Purpose: Skin and soft tissue infections (SSTIs) cause about 15 million cases of infection that result in more than 869,000 annual hospitalizations in the United States. Cellulitis accounted for 63% of all patients hospitalized with SSTIs between 2009 and 2011. The primary objective of this study was to evaluate physician adherence rates to evidence-based practice guidelines. Secondary objectives included evaluating antibiotic selection preferences and duration of therapy. The goal of the project was to generate data to inform the development of a hospital-based protocol for nonnecrotizing SSTI treatment...
May 2018: P & T: a Peer-reviewed Journal for Formulary Management
https://www.readbyqxmd.com/read/29714564/research-misconduct-in-fda-regulated-clinical-trials-a-cross-sectional-analysis-of-warning-letters-and-disqualification-proceedings
#16
Craig A Garmendia, Neera Bhansali, Purnima Madhivanan
BACKGROUND: The US Food and Drug Administration (FDA) ensures that clinical trials meet regulatory and ethical standards through inspections of researchers, also known as clinical investigators. Inspections with significant regulatory/ethical violations may result in regulatory actions, such as a warning letter or a Notice of Initiation of Disqualification Proceedings and Opportunity to Explain (NIDPOE). Objectives included the standardization of regulatory violation themes cited by the FDA for novel analysis of published regulatory actions rate issued by study intervention type, violation theme by intervention type, and violation theme variation between regulatory action type...
January 1, 2018: Therapeutic Innovation & Regulatory Science
https://www.readbyqxmd.com/read/29706729/use-of-a-multivector-mandibular-distractor-for-treatment-of-pediatric-proximal-interphalangeal-joint-pilon-fractures-a-case-based-review
#17
Rachel Pedreira, Brian H Cho, Angela Geer, Ramon A DeJesus
Background: The difficulties in surgical treatment of pilon fractures of the finger include fragment reconstitution and posthealing stiffness. In adults, external fixation with traction and early active range of motion (AROM)/passive range of motion (PROM) during healing is considered necessary for avoiding joint stiffness and attaining realignment. The authors present a unique approach to pediatric pilon fractures that uses open reduction and multivector external fixation with delayed AROM/PROM...
April 2018: Journal of Hand and Microsurgery
https://www.readbyqxmd.com/read/29702506/underserved-pregnant-and-postpartum-women-s-access-and-use-of-their-health-records
#18
Yuqing Guo, Janet Hildebrand, Julie Rousseau, Brandon Brown, Pamela Pimentel, Ellen Olshansky
PURPOSE: The purpose of this study was to examine knowledge of and experiences with use of their electronic health record (EHR) among mostly Hispanic women during pregnancy and postpartum. METHODS: Women who were in the MOMS Orange County prenatal or postpartum home visitation program completed surveys and participated in focus groups. Descriptive and content analyses were used. RESULTS: Twenty-six women participated. Nearly all women (24, 92...
May 2018: MCN. the American Journal of Maternal Child Nursing
https://www.readbyqxmd.com/read/29694241/a-1-5-year-follow-up-of-parent-training-and-atomoxetine-for-attention-deficit-hyperactivity-disorder-symptoms-and-noncompliant-disruptive-behavior-in-autism
#19
L Eugene Arnold, Nicole Ober, Michael G Aman, Benjamin Handen, Tristram Smith, Xueliang Pan, Susan L Hyman, Jill Hollway, Luc Lecavalier, Kristin Page, Robert Rice
OBJECTIVE: To examine status of children with autism spectrum disorder (ASD) 10 months after a 34-week clinical trial of atomoxetine (ATX) and parent training (PT). METHODS: In a 2 × 2 design, 128 children with ASD and attention-deficit/hyperactivity disorder (ADHD) were randomly assigned ATX, PT+placebo, PT+ATX, or placebo alone. PT was weekly for 10 weeks, and then monthly. ATX/placebo was titrated over 6 weeks [≤1.8 mg/kg/d], and then maintained until week 10...
April 25, 2018: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29692216/laser-fenestration-of-aortic-stent-grafts-followed-by-noncompliant-vs-cutting-balloon-dilation-a-scanning-electron-microscopy-study
#20
Jing Lin, Niraj Parikh, Naval Udgiri, Shaoxia Wang, Daniel F Miller, Chaojing Li, Jean Panneton, Mark Nutley, Ze Zhang, Yunfan Huang, Jun Lu, Jingyi Zhang, Lu Wang, Robert Guidoin
PURPOSE: To examine the effects of in situ laser fenestration and subsequent balloon dilation (noncompliant vs cutting) on the graft fabric of 4 aortic stent-graft models. METHOD: In an in vitro setup, the Zenith TX2, Talent, Endurant, and Anaconda aortic stent-grafts (all made of polyester graft material) were subjected to laser fenestration with a 2.3-mm-diameter probe at low and high energy in a physiologic saline solution followed by balloon dilation of the hole...
April 1, 2018: Journal of Endovascular Therapy
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