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https://www.readbyqxmd.com/read/28937062/cryotherapy-intervention-in-relieving-arteriovenous-fistula-cannulation-related-pain-among-hemodialysis-patients-at-the-king-khalid-hospital-tabuk-kingdom-of-saudi-arabia
#1
Hamad S Al Amer, Wireen Leila Dator, Hamzeh Y Abunab, Mohammad Mari
Pain during arteriovenous fistula (AVF) cannulation remains a common problem in hemodialysis (HD) patients that leads to noncompliance to lifetime maintenance HD. This study was performed to determine the effect of cryotherapy on reducing pain during AVF cannulation among HD patients in the King Khalid Hospital, Tabuk, Kingdom of Saudi Arabia. This is an experimental study which included 62 patients undergoing HD through an AVF. Randomization was used to assign the patients into the experimental (received cryotherapy) and control (no cryotherapy) groups...
September 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28933699/pyoderma-gangrenosum-an-uncommon-case-report-and-review-of-the-literature
#2
António Carlos Lemos, Debora Aveiro, Natália Santos, Vítor Marques, Luís Filipe Pinheiro
BACKGROUND: Pyoderma gangrenosum (PG) is a rare ulcerative condition that is diagnostically and therapeutically challenging, as debridement leads to ulcer deterioration (pathergy phenomenon); immunosuppression is considered the gold standard therapy. CASE REPORT: The authors present the case of a 42-year-old woman with PG and uncontrolled iatrogenic diabetes, secondary to a total pancreatectomy performed in another hospital in 1998 due to nesidioblastosis. In 2008, she was referred to the diabetic foot consultation at Centro Hospitalar Tondela-Viseu (Viseu, Portugal) due to an infected wound on the left leg thought to be related to a trauma from footwear, but the injury worsened despite treatment...
September 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28931197/study-of-factors-responsible-for-recidivism-in-allergic-fungal-rhinosinusitis
#3
Bipin Kishore Prasad
Patients with allergic fungal rhinosinusitis (AFRS) are typically atopic and immunocompetent. Despite combined modality treatment based on surgery and immunomodulation, the potential for recidivism is well recognized. A study was conducted in a military hospital in India to identify the factors responsible for recidivism in AFRS and to suggest measures to overcome it. Sixty patients with AFRS (42 new cases and 18 cases that required revision surgery) were managed between January 2009 and July 2013. Patients underwent endoscopic, radiologic, and laboratory evaluation for AFRS followed by functional endoscopic sinus surgery...
September 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28929039/platinum-based-chemotherapy-secures-effective-local-control-for-very-advanced-hereditary-triple-negative-breast-cancer-with-life-threatening-bleeding
#4
Arvids Irmejs, Peteris Loza, Elina Skuja, Janis Gardovskis
Here we report the case of a noncompliant 50-year-old female patient with high-grade, triple-negative breast cancer (TNBC) and strong family cancer history. She only agreed to start treatment after being admitted to the hospital with advanced stage disease and severe anaemia resulting from bulky, ulcerated, and actively bleeding tumor. Therapy was promptly started with platinum-based chemotherapy, resulting in extremely rapid clinical remission and complete control of local symptoms. In conclusion, we hypothesise that even a single course of platinum-based chemotherapy could bring under control life-threatening complications in hereditary TNBC and, therefore, it should be administered without hesitation in emergency circumstances if the patient can tolerate one dose of the medication...
July 10, 2017: Curēus
https://www.readbyqxmd.com/read/28919769/evaluating-the-antiemetic-administration-consistency-to-prevent-chemotherapy-induced-nausea-and-vomiting-with-the-standard-guidelines-a-prospective-observational-study
#5
Afsaneh Vazin, Davood Eslami, Ebrahim Sahebi
Nausea and vomiting (NV) are the most prevalent adverse effects of chemotherapy (CT). This study was conducted to evaluate adherence of the health care team to standard guidelines for antiemetics usage to prevent acute chemotherapy-induced nausea and vomiting (CINV) in a large CT center. A prospective study was performed during an 11-month period on patients receiving CT. A form was designed to collect patients' demographic information and their chemotherapeutic and antiemetic regimen data. The Likert scale was used to measure the effectiveness of the antiemetics in patients...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28914188/a-retrospect-study-on-thiazole-derivatives-as-the-potential-antidiabetic-agents-in-drug-discovery-amp-developments
#6
Gopal L Khatik, Ashok Kumar Datusalia, Waquar Ahsan, Paranjeet Kaur, Manish Vyas, Amit Mittal, Surendra Kumar Nayak
BACKGROUND: Heterocycles containing thiazole, a moiety with sulfur and nitrogen is a core structure which found in a number of biologically active compounds. The thiazole ring is notable as a component of the certain natural products, such as vitamin B1 (thiamine) and penicillins. Thiazole is also known as wonder nucleus and has versatile in different biological fields. A number of new compounds contain heterocycle thiazole moieties, thus it is one of the important areas of research. METHODS: We searched the scientific database using relevant keywords...
September 15, 2017: Current Drug Discovery Technologies
https://www.readbyqxmd.com/read/28905140/long-term-metabolic-follow-up-and-clinical-outcome-of-35-patients-with-maple-syrup-urine-disease
#7
Marie-Thérèse Abi-Wardé, Célina Roda, Jean-Baptiste Arnoux, Aude Servais, Florence Habarou, Anais Brassier, Clément Pontoizeau, Valérie Barbier, Manuella Bayart, Virginie Leboeuf, Bernadette Chadefaux-Vekemans, Sandrine Dubois, Murielle Assoun, Claire Belloche, Jean-Meidi Alili, Marie-Caroline Husson, Fabrice Lesage, Laurent Dupic, Benoit Theuil, Chris Ottolenghi, Pascale de Lonlay
BACKGROUND: Maple syrup urine disease (MSUD) is a rare disease that requires a protein-restricted diet for successful management. Little is known, however, about the psychosocial outcome of MSUD patients. This study investigates the relationship between metabolic and clinical parameters and psychosocial outcomes in a cohort of patients with neonatal-onset MSUD. METHODS: Data on academic achievement, psychological care, family involvement, and biochemical parameters were collected from the medical records of neonatal MSUD patients treated at Necker Hospital (Paris) between 1964 and 2013...
September 13, 2017: Journal of Inherited Metabolic Disease
https://www.readbyqxmd.com/read/28902701/diabetes-self-management-education-training-for-community-health-center-nurses-in-indonesia-a-best-practice-implementation-project
#8
Sugiharto Sugiharto, Matthew Stephenson, Yu-Yun Hsu, Nuniek Nizmah Fajriyah
BACKGROUND: Diabetes complications can increase progressively, leading to morbidity and mortality among diabetes sufferers. To address this, diabetes self-management education is a strategy to increase patients' knowledge and awareness in self-care. However some issues related to diabetes self-management education have emerged for health care providers and patients. OBJECTIVES: The objective of this project was to improve nurses' skills and confidence in delivering diabetes self-management education among type 2 diabetes patients by promoting evidence based practice in community health centers, thereby enhancing patients' knowledge and skills in performing self-care...
September 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28887351/using-predictive-analytics-and-big-data-to-optimize-pharmaceutical-outcomes
#9
Inmaculada Hernandez, Yuting Zhang
PURPOSE: The steps involved, the resources needed, and the challenges associated with applying predictive analytics in healthcare are described, with a review of successful applications of predictive analytics in implementing population health management interventions that target medication-related patient outcomes. SUMMARY: In healthcare, the term big data typically refers to large quantities of electronic health record, administrative claims, and clinical trial data as well as data collected from smartphone applications, wearable devices, social media, and personal genomics services; predictive analytics refers to innovative methods of analysis developed to overcome challenges associated with big data, including a variety of statistical techniques ranging from predictive modeling to machine learning to data mining...
September 15, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28875827/multiple-myeloma-associated-intestinal-amyloidosis-intestinal-pseudo-obstruction-falsely-considered-as-an-ascites
#10
Vladimir Milivojevic, Maja Stojanovic, Ivan Rankovic, Marjan Micev, Rada Jesic Vukicevic, Tomica Milosavljevic
INTRODUCTION: Amyloidosis is a group of diseases pathohistologicaly diagnosed by characteristic extracellular deposition of an abnormal fibrillary protein (i.e. amyloid) into organs, leading to organ dysfunction secondary to destruction of normal tissue architecture. METHOD: Case-report of a 44 year-old female, presenting with massive abdominal distension clinically suspected of ascites. RESULTS: On admission, the patient was complaining of nausea, vomiting, abdominal pain, distension and bloating associated with weight loss and diarrhea...
August 29, 2017: Reviews on Recent Clinical Trials
https://www.readbyqxmd.com/read/28875096/narrow-complex-ventricular-tachycardia
#11
Murtaza Sundhu, Mehmet Yildiz, Sajjad Gul, Mubbasher Syed, Idrees Azher, Robert Mosteller
Myocardial infarctions are frequently complicated by tachyarrhythmias, which commonly have wide QRS complexes (QRS duration > 120 milliseconds). Many published criteria exist to help differentiate between ventricular and supraventricular mechanisms. We present a case of a 61-year-old male with a history of hypertension, hyperlipidemia and coronary artery disease with prior stenting of the right coronary artery (RCA). He had been noncompliant with his antiplatelet medication and presented with cardiac arrest secondary to in-stent thrombosis...
July 4, 2017: Curēus
https://www.readbyqxmd.com/read/28871584/selected-aspects-of-medical-care-for-patients-with-asthma-and-chronic-obstructive-pulmonary-disease-copd-in-poland
#12
Joanna Miłkowska-Dymanowska, Adam J Białas, Paweł Górski
INTRODUCTION: Noncompliance with healthcare undoubtedly has a strong influence on the high prevalence of uncontrolled obstructive diseases. The aim of our study was to evaluate the quality of medical conduct in patients with asthma or chronic obstructive lung diseases (COPD), with encompassed two-levelled system of health care. MATERIAL AND METHODS: A survey of general practitioners (GP), allergists and pulmonologists practicing in Poland was performed between September and December 2016...
2017: Advances in Respiratory Medicine
https://www.readbyqxmd.com/read/28865685/association-between-compliance-with-triage-directions-from-an-organized-state-trauma-system-and-trauma-outcomes
#13
Benjamin Martinez, John T Owings, Christopher Hector, Paige Hargrove, Shoichiro Tanaka, Margaret Moore, Patrick Greiffenstein, Joseph Giaimo, Shahrzad Talebinejad, John P Hunt
BACKGROUND: The Louisiana Emergency Response Network (LERN), a statewide trauma system, has a single communication center with real-time data on hospital capacity across the state. With these data, scene information, and a standardized triage protocol, prehospital providers are directed to the most appropriate hospital. The purpose of our study was to compare outcomes between those patients who complied with the LERN communication center direction and those who did not. STUDY DESIGN: Trauma patients directed by LERN from the field in 2014 were included...
August 26, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28859423/a-comparison-of-compliance-and-noncompliance-in-breast-cancer-screening-among-african-american-women
#14
Cindy Davis, Tamara J Cadet, Matthew Moore, Kathleen Darby
African American women are more likely to be diagnosed with late stage breast cancer, due in part to low participation in screening procedures. The purpose of this study was to explore the differences among African American women who were compliant and noncompliant with standard mammography screening recommendations. The study participants were African American women (N = 599) over the age of 40 with no history of cancer, who were recruited to attend a local community health event. Findings revealed that 78 percent of the women reported having had a mammogram within the past year, whereas 22 percent had not...
August 1, 2017: Health & Social Work
https://www.readbyqxmd.com/read/28853189/clinical-and-angiographic-outcome-of-a-single-center-real-world-population-treated-with-a-dedicated-technique-of-implantation-for-bioresorbable-vascular-scaffolds-the-fatebenefratelli-bioresorbable-vascular-scaffold-fabs-registry
#15
Bernardo Cortese, Gaetano di Palma, Gregory Dendramis, Enrico Cerrato, Roberto A Latini, Mostafa Elwany, Pedro S Orrego, Romano G Seregni
OBJECTIVES: With this prospective study we aim at investigating the long-term outcome of a consecutive cohort of patients successfully treated with bioresorbable scaffold (BVS) implantation. BACKGROUND: It is not clearly understood if there is a relation between the technique of BVS implantation and the outcome. METHODS: Between December 2012 and December 2014, all consecutive patients treated with BVS were included in this registry and received an angiographic follow-up...
August 29, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28847127/in-reply-to-the-letter-to-the-editor-regarding-safety-and-efficacy-of-noncompliant-balloon-angioplasty-for-the-treatment-of-subarachnoid-hemorrhage-induced-vasospasm-a-multicenter-study
#16
LETTER
Christoph J Griessenauer, Apar S Patel, Raghav Gupta, Nimer Adeeb, Paul M Foreman, Hussain Shallwani, Justin M Moore, Mark R Harrigan, Adnan H Siddiqui, Christopher S Ogilvy, Ajith J Thomas
No abstract text is available yet for this article.
September 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28847126/letter-to-the-editor-regarding-safety-and-efficacy-of-noncompliant-balloon-angioplasty-for-the-treatment-of-subarachnoid-hemorrhage-induced-vasospasm-a-multicenter-study
#17
LETTER
https://www.readbyqxmd.com/read/28842107/exercise-and-diabetes-a-narrative-review
#18
REVIEW
David W Jenkins, Alexander Jenks
Persons with diabetes might experience significant benefits through regular exercise. Not unlike the general population, those with diabetes could also lack motivation to participate in an exercise program. Often, those treating persons with diabetes lack training and/or interest in exercise prescription and are therefore unable to provide the needed information and encouragement. In many cases, reluctance to exercise could result from an inability to find an enjoyable exercise activity. Attempts to find activities that, not only provide effective aerobic challenges, but are also enjoyable to participate in are fraught with difficulty...
September 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28833494/echocardiographic-evaluation-of-patients-presenting-with-acutely-decompensated-heart-failure-in-the-setting-of-dietary-or-medication-noncompliance-is-there-a-role
#19
Michael Goyfman, Smadar Kort
BACKGROUND: Reevaluating patients who are admitted with heart failure (HF) exacerbation using echocardiogram is a common and appropriate indication. However, it is unknown whether it is appropriate to reevaluate such patients when the exacerbation is attributed to patients' noncompliance with self-care behaviors, where the presumption is that the underlying HF biology is stable. METHODS: Echocardiograms on all patients hospitalized for HF exacerbation attributed to dietary or medication noncompliance were retrospectively assessed for the presence of significant changes from prior echocardiogram...
August 19, 2017: Echocardiography
https://www.readbyqxmd.com/read/28833307/a-synthetic-estimator-for-the-efficacy-of-clinical-trials-with-all-or-nothing-compliance
#20
Joseph Antonelli, Bing Han, Matthew Cefalu
A critical issue in the analysis of clinical trials is patients' noncompliance to assigned treatments. In the context of a binary treatment with all or nothing compliance, the intent-to-treat analysis is a straightforward approach to estimating the effectiveness of the trial. In contrast, there exist 3 commonly used estimators with varying statistical properties for the efficacy of the trial, formally known as the complier-average causal effect. The instrumental variable estimator may be unbiased but can be extremely variable in many settings...
August 18, 2017: Statistics in Medicine
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