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https://www.readbyqxmd.com/read/27567449/a-smartphone-based-architecture-to-detect-and-quantify-freezing-of-gait-in-parkinson-s-disease
#1
Marianna Capecci, Lucia Pepa, Federica Verdini, Maria Gabriella Ceravolo
INTRODUCTION: The freezing of gait (FOG) is a common and highly distressing motor symptom in patients with Parkinson's Disease (PD). Effective management of FOG is difficult given its episodic nature, heterogeneous manifestation and limited responsiveness to drug treatment. METHODS: In order to verify the acceptance of a smartphone-based architecture and its reliability at detecting FOG in real-time, we studied 20 patients suffering from PD-related FOG. They were asked to perform video-recorded Timed Up and Go (TUG) test with and without dual-tasks while wearing the smartphone...
August 21, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27565186/large-scale-wearable-sensor-deployment-in-parkinson-s-patients-the-parkinson-home-study-protocol
#2
Ana Lígia Silva de Lima, Tim Hahn, Nienke M de Vries, Eli Cohen, Lauren Bataille, Max A Little, Heribert Baldus, Bastiaan R Bloem, Marjan J Faber
BACKGROUND: Long-term management of Parkinson's disease does not reach its full potential because we lack knowledge about individual variations in clinical presentation and disease progression. Continuous and longitudinal assessments in real-life (ie, within the patients' own home environment) might fill this knowledge gap. OBJECTIVE: The primary aim of the Parkinson@Home study is to evaluate the feasibility and compliance of using multiple wearable sensors to collect clinically relevant data...
August 26, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27467066/a-validation-study-of-a-smartphone-based-finger-tapping-application-for-quantitative-assessment-of-bradykinesia-in-parkinson-s-disease
#3
Chae Young Lee, Seong Jun Kang, Sang-Kyoon Hong, Hyeo-Il Ma, Unjoo Lee, Yun Joong Kim
BACKGROUND: Most studies of smartphone-based assessments of motor symptoms in Parkinson's disease (PD) focused on gait, tremor or speech. Studies evaluating bradykinesia using wearable sensors are limited by a small cohort size and study design. We developed an application named smartphone tapper (SmT) to determine its applicability for clinical purposes and compared SmT parameters to current standard methods in a larger cohort. METHODS: A total of 57 PD patients and 87 controls examined with motor UPDRS underwent timed tapping tests (TT) using SmT and mechanical tappers (MeT) according to CAPSIT-PD...
2016: PloS One
https://www.readbyqxmd.com/read/27440289/hello-harlie-enabling-speech-monitoring-through-chat-bot-conversations
#4
David Ireland, Christina Atay, Jacki Liddle, Dana Bradford, Helen Lee, Olivia Rushin, Thomas Mullins, Dan Angus, Janet Wiles, Simon McBride, Adam Vogel
People with neurological conditions such as Parkinson's disease and dementia are known to have difficulties in language and communication. This paper presents initial testing of an artificial conversational agent, called Harlie. Harlie runs on a smartphone and is able to converse with the user on a variety of topics. A description of the application and a sample dialog are provided to illustrate the various roles chat-bots can play in the management of neurological conditions. Harlie can be used for measuring voice and communication outcomes during the daily life of the user, and for gaining information about challenges encountered...
2016: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/27119325/the-use-of-smartphones-for-health-research
#5
E Ray Dorsey, Yu-Feng Yvonne Chan, Michael V McConnell, Stanley Y Shaw, Andrew D Trister, Stephen H Friend
Because of their growing popularity and functionality, smartphones are increasingly valuable potential tools for health and medical research. Using ResearchKit, Apple's open-source platform to build applications ("apps") for smartphone research, collaborators have developed apps for researching asthma, breast cancer, cardiovascular disease, type 2 diabetes, and Parkinson disease. These research apps enhance widespread participation by removing geographical barriers to participation, provide novel ways to motivate healthy behaviors, facilitate high-frequency assessments, and enable more objective data collection...
April 26, 2016: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/27061062/validation-of-a-smartphone-application-measuring-motor-function-in-parkinson-s-disease
#6
Will Lee, Andrew Evans, David R Williams
BACKGROUND: Measurement of motor function is critical to the assessment and management of Parkinson's disease. Ambulatory motor assessment has the potential to provide a glimpse of the patient's clinical state beyond the consultation. We custom-designed a smartphone application that quantitatively measures hand dexterity and hypothesized that this can give an indication of a patient's overall motor function. OBJECTIVE: The aims of this study were to (i) validate this smartphone application against MDS-UPDRS motor assessment (MDS-UPDRS-III) and the two-target tapping test; (ii) generate a prediction model for MDS-UPDRS-III; (iii) assess repeatability of our smartphone application and (iv) examine compliance and user-satisfaction of this application...
April 2, 2016: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/26797614/the-effect-of-personalization-on-smartphone-based-fall-detectors
#7
Carlos Medrano, Inmaculada Plaza, Raúl Igual, Ángel Sánchez, Manuel Castro
The risk of falling is high among different groups of people, such as older people, individuals with Parkinson's disease or patients in neuro-rehabilitation units. Developing robust fall detectors is important for acting promptly in case of a fall. Therefore, in this study we propose to personalize smartphone-based detectors to boost their performance as compared to a non-personalized system. Four algorithms were investigated using a public dataset: three novelty detection algorithms--Nearest Neighbor (NN), Local Outlier Factor (LOF) and One-Class Support Vector Machine (OneClass-SVM)--and a traditional supervised algorithm, Support Vector Machine (SVM)...
2016: Sensors
https://www.readbyqxmd.com/read/26777408/feasibility-and-effects-of-home-based-smartphone-delivered-automated-feedback-training-for-gait-in-people-with-parkinson-s-disease-a-pilot-randomized-controlled-trial
#8
RANDOMIZED CONTROLLED TRIAL
Pieter Ginis, Alice Nieuwboer, Moran Dorfman, Alberto Ferrari, Eran Gazit, Colleen G Canning, Laura Rocchi, Lorenzo Chiari, Jeffrey M Hausdorff, Anat Mirelman
BACKGROUND: Inertial measurement units combined with a smartphone application (CuPiD-system) were developed to provide people with Parkinson's disease (PD) real-time feedback on gait performance. This study investigated the CuPiD-system's feasibility and effectiveness compared with conventional gait training when applied in the home environment. METHODS: Forty persons with PD undertook gait training for 30 min, three times per week for six weeks. Participants were randomly assigned to i) CuPiD, in which a smartphone application offered positive and corrective feedback on gait, or ii) an active control, in which personalized gait advice was provided...
January 2016: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/26776193/personalized-hypothesis-tests-for-detecting-medication-response-in-parkinson-disease-patients-using-iphone-sensor-data
#9
Elias Chaibub Neto, Brian M Bot, Thanneer Perumal, Larsson Omberg, Justin Guinney, Mike Kellen, Arno Klein, Stephen H Friend, Andrew D Trister
We propose hypothesis tests for detecting dopaminergic medication response in Parkinson disease patients, using longitudinal sensor data collected by smartphones. The processed data is composed of multiple features extracted from active tapping tasks performed by the participant on a daily basis, before and after medication, over several months. Each extracted feature corresponds to a time series of measurements annotated according to whether the measurement was taken before or after the patient has taken his/her medication...
2016: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/26737109/unconstrained-detection-of-freezing-of-gait-in-parkinson-s-disease-patients-using-smartphone
#10
Hanbyul Kim, Hong Ji Lee, Woongwoo Lee, Sungjun Kwon, Sang Kyong Kim, Hyo Seon Jeon, Hyeyoung Park, Chae Won Shin, Won Jin Yi, Beom S Jeon, Kwang S Park
Freezing of gait (FOG) is a common motor impairment to suffer an inability to walk, experienced by Parkinson's disease (PD) patients. FOG interferes with daily activities and increases fall risk, which can cause severe health problems. We propose a novel smartphone-based system to detect FOG symptoms in an unconstrained way. The feasibility of single device to sense gait characteristic was tested on the various body positions such as ankle, trouser pocket, waist and chest pocket. Using measured data from accelerometer and gyroscope in the smartphone, machine learning algorithm was applied to classify freezing episodes from normal walking...
August 2015: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/26302523/a-smartphone-based-tool-for-assessing-parkinsonian-hand-tremor
#11
N Kostikis, D Hristu-Varsakelis, M Arnaoutoglou, C Kotsavasiloglou
The aim of this study is to propose a practical smartphone-based tool to accurately assess upper limb tremor in Parkinson's disease (PD) patients. The tool uses signals from the phone's accelerometer and gyroscope (as the phone is held or mounted on a subject's hand) to compute a set of metrics which can be used to quantify a patient's tremor symptoms. In a small-scale clinical study with 25 PD patients and 20 age-matched healthy volunteers, we combined our metrics with machine learning techniques to correctly classify 82% of the patients and 90% of the healthy volunteers, which is high compared to similar studies...
November 2015: IEEE Journal of Biomedical and Health Informatics
https://www.readbyqxmd.com/read/26302109/gait-monitoring-for-early-neurological-disorder-detection-using-sensors-in-a-smartphone-validation-and-a-case-study-of-parkinsonism
#12
Paweeya Raknim, Kun-Chan Lan
BACKGROUND: Diagnosing brain disorders, such as Parkinson's disease (PD) or Alzheimer's disease, is often difficult, especially in the early stages. Moreover, it has been estimated that nearly 40% of people with PD may not be diagnosed. Traditionally, the diagnosis of neurological disorders, such as PD, often required a doctor to observe the patient over time to recognize signs of rigidity in movement. MATERIALS AND METHODS: The pedestrian dead reckoning (PDR) system is a self-contained technique that has been widely used for indoor localization...
January 2016: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/26230306/smartphones-in-the-operating-room-distraction-or-diagnostic-aid-a-case-of-newly-diagnosed-wolff-parkinson-white-in-a-pediatric-patient-having-bronchoscopy-under-general-anesthesia
#13
Brandon Esenther, Riva Ko
A 4-year-old boy presented for elective bronchoscopy after years of pharmacologically unresponsive reactive airway disease that limited physical activity. After mask induction with nitrous oxide and sevoflurane, the patient was noted to be intermittently in a hemodynamically stable tachyarrhythmia. The anesthesia machine, though equipped with electrocardiogram (ECG) recording capabilities, malfunctioned during the case and was not able to print a rhythm strip. As a substitute, a smartphone picture and video were recorded...
August 1, 2015: A & A Case Reports
https://www.readbyqxmd.com/read/26059091/quantitative-home-based-assessment-of-parkinson-s-symptoms-the-sense-park-feasibility-and-usability-study
#14
Joaquim J Ferreira, Catarina Godinho, Ana T Santos, Josefa Domingos, Daisy Abreu, Raquel Lobo, Nilza Gonçalves, Marcio Barra, Frank Larsen, Øyvind Fagerbakke, Ingvild Akeren, Hilde Wangen, J Artur Serrano, Peter Weber, Andrea Thoms, Stefan Meckler, Stefan Sollinger, Janet van Uem, Markus A Hobert, Katrin S Maier, Helen Matthew, Tom Isaacs, Joy Duffen, Holm Graessner, Walter Maetzler
BACKGROUND: Currently, assessment of symptoms associated with Parkinson's disease is mainly performed in the clinic. However, these assessments have limitations because they provide only a snapshot of the condition. METHODS: The feasibility and usability of an objective, continuous and relatively unobtrusive system (SENSE-PARK System), which consists of wearable sensors (three worn during the day and one worn at night), a smartphone-based App, a balance board and computer software, was tested 24/7 over 12 weeks in a study including 22 PD patients...
2015: BMC Neurology
https://www.readbyqxmd.com/read/25904256/-the-novel-quantitative-measures-of-gait-and-posture-in-parkinson-s-disease-cross-sectional-analysis
#15
Tomoo Mano, Ryoji Nishi, Yosuke Kobayashi, Koji Matsuo, Yasushi Kobayashi, Akio Kakehi
Posture abnormality and gait impairments characterize of Parkinson's disease (PD), predict the risk of falling, and are important contributors to reduced quality of life. The quantitative measures of posture and gait may eventually provide usefulness as a biomarker in PD. This study included that 40 patients with PD (male 26, female 14, average age 70.4 ± 7.6 years old) and 17 normal healthy controls. We selected the quantified measures of the gait function, such as MDS-UPDRS, Timed up & go test, 5 feet walk test, 6 minutes-walk test...
2015: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/25855044/e-health-support-in-people-with-parkinson-s-disease-with-smart-glasses-a-survey-of-user-requirements-and-expectations-in-the-netherlands
#16
Yan Zhao, Tjitske Heida, Erwin E H van Wegen, Bastiaan R Bloem, Richard J A van Wezel
Recent advances in smart glasses, wearable computers in the form of glasses, bring new therapeutic and monitoring possibilities for people with Parkinson's disease (PD). For example, it can provide visual and auditory cues during activities of daily living that have long been used to improve gait disturbances. Furthermore, smart glasses can personalize therapies based on the state of the user and/or the user environment in real-time using object recognition and motion tracking. To provide guidelines for developers in creating new PD applications for smart glasses, a self-reported questionnaire was designed to survey the requirements, constraints, and attitudes of people with PD with respect to this new technology...
2015: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/25830687/a-mobile-cloud-based-parkinson-s-disease-assessment-system-for-home-based-monitoring
#17
Di Pan, Rohit Dhall, Abraham Lieberman, Diana B Petitti
BACKGROUND: Parkinson's disease (PD) is the most prevalent movement disorder of the central nervous system, and affects more than 6.3 million people in the world. The characteristic motor features include tremor, bradykinesia, rigidity, and impaired postural stability. Current therapy based on augmentation or replacement of dopamine is designed to improve patients' motor performance but often leads to levodopa-induced adverse effects, such as dyskinesia and motor fluctuation. Clinicians must regularly monitor patients in order to identify these effects and other declines in motor function as soon as possible...
2015: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/25819808/detecting-and-monitoring-the-symptoms-of-parkinson-s-disease-using-smartphones-a-pilot-study
#18
S Arora, V Venkataraman, A Zhan, S Donohue, K M Biglan, E R Dorsey, M A Little
BACKGROUND: Remote, non-invasive and objective tests that can be used to support expert diagnosis for Parkinson's disease (PD) are lacking. METHODS: Participants underwent baseline in-clinic assessments, including the Unified Parkinson's Disease Rating Scale (UPDRS), and were provided smartphones with an Android operating system that contained a smartphone application that assessed voice, posture, gait, finger tapping, and response time. Participants then took the smart phones home to perform the five tasks four times a day for a month...
June 2015: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/25626550/use-of-smartphones-and-portable-media-devices-for-quantifying-human-movement-characteristics-of-gait-tendon-reflex-response-and-parkinson-s-disease-hand-tremor
#19
Robert LeMoyne, Timothy Mastroianni
Smartphones and portable media devices are both equipped with sensor components, such as accelerometers. A software application enables these devices to function as a robust wireless accelerometer platform. The recorded accelerometer waveform can be transmitted wireless as an e-mail attachment through connectivity to the Internet. The implication of such devices as a wireless accelerometer platform is the experimental and post-processing locations can be placed anywhere in the world. Gait was quantified by mounting a smartphone or portable media device proximal to the lateral malleolus of the ankle joint...
2015: Methods in Molecular Biology
https://www.readbyqxmd.com/read/25600193/empirical-studies-on-usability-of-mhealth-apps-a-systematic-literature-review
#20
REVIEW
Belén Cruz Zapata, José Luis Fernández-Alemán, Ali Idri, Ambrosio Toval
The release of smartphones and tablets, which offer more advanced communication and computing capabilities, has led to the strong emergence of mHealth on the market. mHealth systems are being used to improve patients' lives and their health, in addition to facilitating communication between doctors and patients. Researchers are now proposing mHealth applications for many health conditions such as dementia, autism, dysarthria, Parkinson's disease, and so on. Usability becomes a key factor in the adoption of these applications, which are often used by people who have problems when using mobile devices and who have a limited experience of technology...
February 2015: Journal of Medical Systems
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