Samer Alabed, Pankaj Garg, Faisal Alandejani, Krit Dwivedi, Ahmed Maiter, Kavita Karunasaagarar, Smitha Rajaram, Catherine Hill, Steven Thomas, Rebecca Gossling, Michael J Sharkey, Mahan Salehi, Jim M Wild, Lisa Watson, Abdul Hameed, Athanasios Charalampopoulos, Haiping Lu, Alex M K Rothman, A A Roger Thompson, Charlie A Elliot, Neil Hamilton, Christopher S Johns, Iain Armstrong, Robin Condliffe, Rob J van der Geest, Andrew J Swift, David G Kiely
BACKGROUND: Cardiac magnetic resonance (CMR) is the gold standard technique to assess biventricular volumes and function, and is increasingly being considered as an end-point in clinical studies. Currently, with the exception of right ventricular (RV) stroke volume and RV end-diastolic volume, there is only limited data on minimally important differences (MIDs) reported for CMR metrics. Our study aimed to identify MIDs for CMR metrics based on US Food and Drug Administration recommendations for a clinical outcome measure that should reflect how a patient "feels, functions or survives"...
August 2023: European Respiratory Journal