keyword
MENU ▼
Read by QxMD icon Read
search

Sodium bicarbonate

keyword
https://www.readbyqxmd.com/read/29345400/fludrocortisone-a-treatment-for-tubulopathy-post-paediatric-renal-transplantation-a-national-paediatric-nephrology-unit-experience
#1
S R Ali, I Shaheen, D Young, I Ramage, H Maxwell, D A Hughes, D Athavale, M G Shaikh
Calcineurin inhibitors post-renal transplantation are recognized to cause tubulopathies in the form of hyponatremia, hyperkalemia, and acidosis. Sodium supplementation may be required, increasing medication burden and potentially resulting in poor compliance. Fludrocortisone has been beneficial in addressing tubulopathies in adult studies, with limited paediatric data available. A retrospective review of data from an electronic renal database from December 2014 to January 2016 was carried out. Forty-seven post-transplant patients were reviewed with 23 (49%) patients on sodium chloride or bicarbonate...
January 18, 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29345173/effects-of-3-day-serial-sodium-bicarbonate-loading-on-performance-and-physiological-parameters-during-a-simulated-basketball-test-in-female-university-players
#2
Anne Delextrat, Sinead MacKessy, Luis Arceo-Rendon, Aaron Scanlan, Roger Ramsbottom, Julio Calleja-González
The aim of this study was to investigate the effect of 3-day serial sodium bicarbonate ingestion on repeated sprint and jump performance. Fifteen female university basketball players (23.3±3.4 years; 173.1±5.8 cm; 65.8±6.3 kg; 23.6±4.9% body fat) ingested 0.4 g·kg-1 of body mass of sodium bicarbonate or placebo for 3 days (split in 3 equal daily doses), before completing a simulated basketball exercise. Sprint and circuit times, jump heights, performance decrements and gastrointestinal (GI) side effects were recorded during the test and blood lactate concentration was measured pre- and post-test...
January 18, 2018: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29344729/sodium-bicarbonate-supplementation-improves-severe-intensity-intermittent-exercise-under-moderate-acute-hypoxic-conditions
#3
Sanjoy K Deb, Lewis A Gough, S Andy Sparks, Lars R McNaughton
Acute moderate hypoxic exposure can substantially impair exercise performance, which occurs with a concurrent exacerbated rise in hydrogen cation (H+) production. The purpose of this study was therefore, to alleviate this acidic stress through sodium bicarbonate (NaHCO3) supplementation and determine the corresponding effects on severe-intensity intermittent exercise performance. Eleven recreationally active individuals participated in this randomised, double-blind, crossover study performed under acute normobaric hypoxic conditions (FiO2% = 14...
January 17, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29344054/the-carnitine-status-does-not-affect-the-contractile-and-metabolic-phenotype-of-skeletal-muscle-in-pigs
#4
Daniel Kaup, Janine Keller, Erika Most, Joachim Geyer, Klaus Eder, Robert Ringseis
Background: Recently, supplementation of L-carnitine to obese rats was found to improve the carnitine status and to counteract an obesity-induced muscle fiber transition from type I to type II. However, it has not been resolved if the change of muscle fiber distribution induced in obese rats and the restoration of the "normal" muscle fiber distribution, which is found in lean rats, in obese rats by supplemental L-carnitine is causally linked with the carnitine status. In the present study we hypothesized that fiber type distribution in skeletal muscle is dependent on carnitine status...
2018: Nutrition & Metabolism
https://www.readbyqxmd.com/read/29340523/a-case-of-severe-glutathione-synthetase-deficiency-with-novel-gss-mutations
#5
H Xia, J Ye, L Wang, J Zhu, Z He
Glutathione synthetase deficiency (GSSD) is a rare inborn error of glutathione metabolism with autosomal recessive inheritance. The severe form of the disease is characterized by acute metabolic acidosis, usually present in the neonatal period with hemolytic anemia and progressive encephalopathy. A case of a male newborn infant who had severe metabolic acidosis with high anion gap, hemolytic anemia, and hyperbilirubinemia is reported. A high level of 5-oxoproline was detected in his urine and a diagnosis of generalized GSSD was made...
January 11, 2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29340313/treatment-of-severe-hyperkalemia-confronting-4-fallacies
#6
REVIEW
J Gary Abuelo
Severe hyperkalemia is a medical emergency that can cause lethal arrhythmias. Successful management requires monitoring of the electrocardiogram and serum potassium concentrations, the prompt institution of therapies that work both synergistically and sequentially, and timely repeat dosing as necessary. It is of concern then that, based on questions about effectiveness and safety, many physicians no longer use 3 key modalities in the treatment of severe hyperkalemia: sodium bicarbonate, sodium polystyrene sulfonate (Kayexalate [Concordia Pharmaceuticals Inc...
January 2018: KI Reports
https://www.readbyqxmd.com/read/29336990/failure-of-intracardiac-pacing-after-fatal-propafenone-overdose-a-case-report
#7
Ivan Zeljković, Nikola Bulj, Matea Kolačević, Vedran Čabrilo, Diana Delić Brkljačić, Šime Manola
BACKGROUND: Propafenone is a sodium-channel blocker, class IC antiarrhythmic drug, frequently used to manage supraventricular dysrhythmias, especially atrial fibrillation. We report a self mono-intoxication with propafenone. CASE REPORT: A 68-year-old woman presented with a decreased level of consciousness, hypotension, and electrocardiogram showing QRS widening with atrial asystole and extreme bradycardia < 20 beats/min. After initial stabilization with transcutaneous pacing, laboratory findings detected normal electrolyte ranges and metabolic acidosis, and her medical history revealed availability of propafenone due to paroxysmal atrial fibrillation and depressive syndrome, which led to the suspicion of intoxication...
January 11, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29328017/-hydration-to-prevent-contrast-induced-nephropathy
#8
E J Hoorn, R Zietse
In 2007, a national guideline was issued in the Netherlands to prevent contrast-induced nephropathy. This guideline recommended preventive hydration with 0.9% NaCl in patients with reduced estimated glomerular filtration rate (eGFR 30-69 ml/min/1.73 m2) prior to administration of contrast. The recent AMACING study compared hydration versus no hydration, and found that hydration did not prevent contrast-induced nephropathy but did lead to complications and higher costs. The latest 2017 guideline recommends hydration only for patients with eGFR < 30 ml/min/1...
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29310826/changes-in-v-atpase-subunits-of-human-urinary-exosomes-reflect-the-renal-response-to-acute-acid-alkali-loading-and-the-defects-in-distal-renal-tubular%C3%A2-acidosis
#9
Ganesh Pathare, Nasser A Dhayat, Nilufar Mohebbi, Carsten A Wagner, Ion A Bobulescu, Orson W Moe, Daniel G Fuster
In the kidney, final urinary acidification is achieved by V-ATPases expressed in type A intercalated cells. The B1 subunit of the V-ATPase is required for maximal urinary acidification, while the role of the homologous B2 subunit is less clear. Here we examined the effect of acute acid/alkali loading in humans on B1 and B2 subunit abundance in urinary exosomes in normal individuals and of acid loading in patients with distal renal tubular acidosis (dRTA). Specificities of B1 and B2 subunit antibodies were verified by yeast heterologously expressing human B1 and B2 subunits, and murine wild-type and B1-deleted kidney lysates...
January 6, 2018: Kidney International
https://www.readbyqxmd.com/read/29306258/the-reno-protective-effects-of-atorvastatin-in-crush-syndrome-and-rhabdomyolysis-is-there-a-dilemma
#10
Demet Acar, Mustafa Gülpembe, Can Gökay Yıldız, Emine Nur Özdamar, Kerem Açıkgöz, Ahmet Çağlar, Başar Cander
Background/aim: We aim to determine the effects of low-dose atorvastatin treatment together with crush fluid resuscitation on renal functions and muscle enzyme levels in a rat model of crush syndrome. Materials and methods: The study involved female Wistar Albino rats weighing 250-300 g that were housed with free access to food and water. The crush model was obtained by compression. Rats were randomly divided into four groups: control (C) group, atorvastatin + crush fluid (ACF) group, crush fluid (CF) group, and hypertonic saline (%3) + mannitol + sodium bicarbonate (SM) group...
December 19, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29300678/simultaneous-extraction-and-enrichment-of-reactive-dye-using-green-emulsion-liquid-membrane-system
#11
Norasikin Othman, Raja Norimie Raja Sulaiman, Hilmi Abdul Rahman, Norul Fatiha Mohamad Noah, Norela Jusoh, Mariani Idroas
Currently, an extractive green palm oil based emulsion liquid membrane (ELM) has been used for simultaneous extraction and enrichment of Reactive Red 3BS from simulated synthetic dye wastewater. The ELM consists of two main phases which are organic liquid membrane and stripping solution. During the extraction process, the ELM was dispersed into the simulated synthetic dye wastewater containing the Reactive Red 3BS complexes. The organic liquid membrane contained Tridodecylamine (TDA), Sorbitan Monooleate (Span 80) and palm oil as a carrier, surfactant and diluent, respectively...
January 4, 2018: Environmental Technology
https://www.readbyqxmd.com/read/29297841/health-status-of-red-footed-boobies-sula-sula-determined-by-hematology-biochemistry-blood-gases-and-physical-examination
#12
Gregory A Lewbart, Catalina Ulloa, Diane Deresienski, Cristina Regalado, Juan-Pablo Muñoz-Pérez, Juan Garcia, Britta Denise Hardesty, Carlos A Valle
The red-footed booby ( Sula sula) is a widely distributed sulid native to the Galápagos archipelago. Hematology and blood chemistry parameters have been published for this species, but not from the San Cristóbal rookery. Analyses were run on blood samples drawn from 31 manually restrained red-footed boobies that were captured by hand from their nests at Punta Pitt on San Cristóbal Island. A portable blood analyzer (iSTAT) was used to obtain near immediate field results for pH, partial pressure of oxygen, partial pressure of carbon dioxide, bicarbonate, hematocrit, hemoglobin, sodium, potassium, ionized calcium, and glucose...
December 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/29295656/core-shell-poly-lactide-co-%C3%AE%C2%B5-caprolactone-gelatin-fiber-scaffolds-as-ph-sensitive-drug-delivery-systems
#13
Qingqing Sang, Heyu Li, Gareth Williams, Huanling Wu, Li-Min Zhu
Dual-drug-loaded pH-responsive fiber scaffolds were successfully prepared by coaxial electrospinning. These were designed with the aim of being sutured into the resection site after tumor removal, to aid recovery and prevent cancer recurrence. The shell was made up of a mixture of gelatin and sodium bicarbonate (added to provide pH-sensitivity), and was loaded with the anti-inflammatory drug ciprofloxacin; the core comprised poly(lactide-co-ε-caprolactone) with the chemotherapeutic doxorubicin hydrochloride...
January 1, 2018: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/29284875/efficacy-and-safety-of-using-air-versus-alkalinized-2-lignocaine-for-inflating-endotracheal-tube-cuff-and-its-pressure-effects-on-incidence-of-postoperative-coughing-and-sore-throat
#14
Pallavi Gaur, Pravin Ubale, Prashant Khadanga
Background and Objective: We wished to compare the endotracheal tube (ETT) cuff pressure inflated with air or alkalinized lignocaine during anesthesia and evaluate clinical symptoms such as coughing and sore throat (postoperative sore throat [POST]) following tracheal extubation. Materials and Methods: This was a prospective randomized controlled study conducted in a tertiary care set up over a period of 1 year. We included 100 patients in age group of 18-65 years posted for elective surgeries of duration more than 90 min under general anesthesia with N2O-O2 mixture...
October 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29284355/stability-of-sodium-bicarbonate-injection-8-4-in-syringes-over-a-six-week-period-in-refrigerated-temperature
#15
Jack T Seki, Tian Q Wang, Paul M Yip, Tony Mazzulli, Mark D Minden
Background Dysfunctional central venous catheter prohibits the administration of potential life-saving chemotherapy and the delivery of essential supportive care needs to patients. Sodium bicarbonate injection has been shown to impede against fibrin clot formation and prolong prothrombin time and thrombin clotting time. Sodium bicarbonate injection has been tried as a second-line agent with good results in a small number of patients (internal data not published) when alteplase failed. We assessed whether the pre-filled sodium bicarbonate injection in 5 mL syringes would not only preserve sterility and retain its pH and concentration but also amount to the potential cost savings for future use when stored in a refrigerated environment...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29277725/a-hybrid-approach-to-predict-the-relationship-between-tablet-tensile-strength-and-compaction-pressure-using-analytical-powder-compression
#16
Ann-Sofie Persson, Göran Alderborn
The objective was to present a hybrid approach to predict the strength-pressure relationship (SPR) of tablets using common compression parameters and a single measurement of tablet tensile strength. Experimental SPR were derived for six pharmaceutical powders with brittle and ductile properties and compared to predicted SPR based on a three-stage approach. The prediction was based on the Kawakita b-1 parameter and the in-die Heckel yield stress, an estimate of maximal tensile strength, and a parameter proportionality factor α...
December 22, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/29249420/hemodynamic-factors-associated-with-serum-chloride-in-ambulatory-patients-with-advanced-heart-failure
#17
Justin L Grodin, Wilfried Mullens, Matthias Dupont, David O Taylor, Paul M McKie, Randall C Starling, Jeffrey M Testani, W H Wilson Tang
BACKGROUND: Lower serum chloride (Cl) is associated with mortality in heart failure patients and may be more prognostically relevant than sodium. However, the association of hemodynamics and Cl levels is unknown. METHODS: 438 sequential patients with advanced chronic heart failure (ACHF) underwent invasive hemodynamic assessment with measured serum Cl levels during an evaluation for ACHF. Patients were followed for death, heart transplant (HT), or ventricular assist device placement (VAD)...
February 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29243327/fluorine-containing-silsesquioxanes-based-hybrid-porous-polymers-mediated-by-bases-and-their-use-in-water-remediation
#18
Hongzhi Liu
Two different silsesquioxane-based porous polymers (FHPPs), i.e. FHPP-1 and FHPP-2 were prepared, respectively, by changing acid scavengers from sodium bicarbonate to triethylamine in the Heck reaction between octavinylsilsesquioxane (OVS) and 1, 4-dibromotetrafluorobenzene. It was observed that defluorination occurred in the case of triethylamine. FHPP-1 possessed higher surface area of 600 m2 g-1 and a hierarchical pore structure; in contrast, FHPP-2 possessed SBET of 325 m2 g-1 and a microporous structure...
December 15, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29239964/superior-efficacy-of-lipid-emulsion-infusion-over-serum-alkalinization-in-reversing-amitriptyline-induced-cardiotoxicity-in-guinea-pig
#19
Shogo Tsujikawa, Tadashi Matsuura, Kotaro Hori, Takashi Mori, Miyuki Kuno, Kiyonobu Nishikawa
BACKGROUND: Tricyclic antidepressants (TCAs) are a major cause of fatal drug poisoning due to their cardiotoxicity. Alkalinization by sodium bicarbonate (NaHCO3) administration, the first-line therapy for TCA-induced cardiotoxicity, can occasionally yield insufficient efficacy in severe cases. Because most TCAs are highly lipophilic, lipid emulsion may be more effective than alkalinization. However, it remains to be determined whether lipid emulsion is more beneficial than alkalinization in reversing amitriptyline-induced cardiotoxicity...
December 11, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29226898/severe-cardiac-toxicity-following-alcohol-intake-in-a-patient-using-therapeutic-dose-of-propafenone
#20
Zübeyde Bayram, Ahmet Güner, Cem Doğan, Fatih Yılmaz, Nihal Özdemir
An unconscious, 25-year-old, male patient was brought to the emergency department. The patient's electrocardiography demonstrated a wide QRS interval and first-degree atrioventricular block. He was being treated with propafenone twice daily (450 mg) for paroxysmal atrial fibrillation. The patient had consumed a substantial amount of alcohol the day before. He recovered after supportive management with sodium bicarbonate and inotropic therapy. In the presently described case, treatment resulted in quick normalization of QRS interval and stabilization of hemodynamic status...
December 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
keyword
keyword
39130
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"