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https://www.readbyqxmd.com/read/29348023/impaired-recovery-of-left-ventricular-function-in-patients-with-cardiomyopathy-and-left%C3%A2-bundle-branch-block
#1
Edward Sze, Zainab Samad, Allison Dunning, Kristen Bova Campbell, Zak Loring, Brett D Atwater, Karen Chiswell, Joseph A Kisslo, Eric J Velazquez, James P Daubert
BACKGROUND: Patients with left bundle branch block (LBBB) often respond to cardiac resynchronization therapy (CRT) with left ventricular ejection fraction (LVEF) improvement. Guideline-directed medical therapy (GDMT), not CRT, is first-line therapy for patients with reduced LVEF with LBBB. However, there are little data on how patients with reduced LVEF and LBBB respond to GDMT. OBJECTIVES: This study examined patients with cardiomyopathy and sought to assess rates of LVEF improvement for patients with LBBB compared to other QRS morphologies...
January 23, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29345420/integration-of-gas-enhanced-oil-recovery-in-multiphase-fermentations-for-the-microbial-production-of-fuels-and-chemicals
#2
Susana Pedraza-de la Cuesta, Lore Keijzers, Luuk A M van der Wielen, Maria C Cuellar
In multiphase fermentations where the product forms a second liquid phase or where solvents are added for product extraction, turbulent conditions disperse the oil phase as droplets. Surface-active components (SACs) present in the fermentation broth can stabilize the product droplets thus forming an emulsion. Breaking this emulsion increases process complexity and consequently the production cost. In previous works, it has been proposed to promote demulsification of oil/supernatant emulsions in an off-line batch bubble column operating at low gas flow rate...
January 18, 2018: Biotechnology Journal
https://www.readbyqxmd.com/read/29335180/synthesis-of-nanometer-sized-fayalite-and-magnesium-iron-ii-mixture-olivines
#3
Odeta Qafoku, Eugene S Ilton, Mark E Bowden, Libor Kovarik, Xin Zhang, Ravi K Kukkadapu, Mark H Engelhard, Christopher J Thompson, Herbert T Schaef, Bernard Peter McGrail, Kevin M Rosso, John S Loring
Olivines are divalent orthosilicates with important geologic, biological, and industrial significance and are typically comprised of mixtures of Mg2+ and Fe2+ ranging from forsterite (Mg2SiO4) to fayalite (Fe2SiO4). Investigating the role of Fe(II) in olivine reactivity requires the ability to synthesize olivines that are nanometer-sized, have different percentages of Mg2+ and Fe2+, and have good bulk and surface purity. This article demonstrates a new method for synthesizing nanosized fayalite and Mg-Fe mixture olivines...
January 10, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29331230/lower-limb-articular-scaling-and-body-mass-estimation-in-pliocene-and-pleistocene-hominins
#4
Christopher B Ruff, M Loring Burgess, Nicole Squyres, Juho-Antti Junno, Erik Trinkaus
Previous attempts to estimate body mass in pre-Holocene hominins have relied on prediction equations derived from relatively limited extant samples. Here we derive new equations to predict body mass from femoral head breadth and proximal tibial plateau breadth based on a large and diverse sample of modern humans (avoiding the problems associated with using diaphyseal dimensions and/or cadaveric reference samples). In addition, an adjustment for the relatively small femoral heads of non-Homo taxa is developed based on observed differences in hip to knee joint scaling...
January 10, 2018: Journal of Human Evolution
https://www.readbyqxmd.com/read/29320760/a-standard-nomenclature-for-referencing-and-authentication-of-pluripotent-stem-cells
#5
REVIEW
Andreas Kurtz, Stefanie Seltmann, Amos Bairoch, Marie-Sophie Bittner, Kevin Bruce, Amanda Capes-Davis, Laura Clarke, Jeremy M Crook, Laurence Daheron, Johannes Dewender, Adam Faulconbridge, Wataru Fujibuchi, Alexander Gutteridge, Derek J Hei, Yong-Ou Kim, Jung-Hyun Kim, Anja Kolb- Kokocinski, Fritz Lekschas, Geoffrey P Lomax, Jeanne F Loring, Tenneille Ludwig, Nancy Mah, Tohru Matsui, Robert Müller, Helen Parkinson, Michael Sheldon, Kelly Smith, Harald Stachelscheid, Glyn Stacey, Ian Streeter, Anna Veiga, Ren-He Xu
Unambiguous cell line authentication is essential to avoid loss of association between data and cells. The risk for loss of references increases with the rapidity that new human pluripotent stem cell (hPSC) lines are generated, exchanged, and implemented. Ideally, a single name should be used as a generally applied reference for each cell line to access and unify cell-related information across publications, cell banks, cell registries, and databases and to ensure scientific reproducibility. We discuss the needs and requirements for such a unique identifier and implement a standard nomenclature for hPSCs, which can be automatically generated and registered by the human pluripotent stem cell registry (hPSCreg)...
January 9, 2018: Stem Cell Reports
https://www.readbyqxmd.com/read/29315274/synthesized-heparan-sulfate-competitors-attenuate-pseudomonas-aeruginosa-lung-infection
#6
Nicola Ivan Lorè, Noemi Veraldi, Camilla Riva, Barbara Sipione, Lorenza Spagnuolo, Ida De Fino, Medede Melessike, Elisa Calzi, Alessandra Bragonzi, Annamaria Naggi, Cristina Cigana
Several chronic respiratory diseases are characterized by recurrent and/or persistent infections, chronic inflammatory responses and tissue remodeling, including increased levels of glycosaminoglycans which are known structural components of the airways. Among glycosaminoglycans, heparan sulfate (HS) has been suggested to contribute to excessive inflammatory responses. Here, we aim at (i) investigating whether long-term infection by Pseudomonas aeruginosa, one of the most worrisome threat in chronic respiratory diseases, may impact HS levels, and (ii) exploring HS competitors as potential anti-inflammatory drugs during P...
January 9, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29308213/case-series-of-3-patients-diagnosed-with-atypical-hemolytic-uremic-syndrome-successfully-treated-with-steroids-plasmapheresis-and-rituximab
#7
Jeffery M Patterson, Lauren Bolster, Loree Larratt
Rationale: Atypical hemolytic uremic syndrome, which has a high probability of chronic kidney disease, morbidity, and mortality, needs to be promptly recognized when patients present with microangiopathic hemolysis. Presenting Concerns of the Patient: Three patients present with laboratory parameters consistent with a thrombotic microangiopathy. With a suspected diagnosis of thrombotic thrombocytopenic purpura, steroids with plasmapheresis were initiated. Diagnoses: With ADAMTS13 levels reported normal, the suspected diagnoses were reevaluated...
2018: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/29302270/back-to-the-future-in-a-petri-dish-origin-and-impact-of-resurrected-microbes-in-natural-populations
#8
REVIEW
Shira Houwenhuyse, Emilie Macke, Lien Reyserhove, Lore Bulteel, Ellen Decaestecker
Current natural populations face new interactions because of the re-emergence of ancient microbes and viruses. These risks come from the re-emergence of pathogens kept in laboratories or from pathogens that are retained in the permafrost, which become available upon thawing due to climate change. We here focus on the effects of such re-emergence in natural host populations based on evolutionary theory of virulence and long-term studies, which investigate host-pathogen adaptations. Pathogens tend to be locally and temporally adapted to their co-occurring hosts, but when pathogens from a different environment or different time enter the host community, the degree to which a new host-pathogen interaction is a threat will depend on the specific genotypic associations, the time lag between the host and the pathogen, and the interactions with native or recent host and pathogen species...
January 2018: Evolutionary Applications
https://www.readbyqxmd.com/read/29301111/a-deep-learning-framework-for-causal-shape-transformation
#9
Kin Gwn Lore, Daniel Stoecklein, Michael Davies, Baskar Ganapathysubramanian, Soumik Sarkar
Recurrent neural network (RNN) and Long Short-term Memory (LSTM) networks are the common go-to architecture for exploiting sequential information where the output is dependent on a sequence of inputs. However, in most considered problems, the dependencies typically lie in the latent domain which may not be suitable for applications involving the prediction of a step-wise transformation sequence that is dependent on the previous states only in the visible domain with a known terminal state. We propose a hybrid architecture of convolution neural networks (CNN) and stacked autoencoders (SAE) to learn a sequence of causal actions that nonlinearly transform an input visual pattern or distribution into a target visual pattern or distribution with the same support and demonstrated its practicality in a real-world engineering problem involving the physics of fluids...
December 18, 2017: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/29300275/proactive-risk-mitigation-using-failure-modes-and-effects-analysis-for-evaluating-vascular-access
#10
Shea Polancich, Loring Rue, Terri Poe, Rebecca Miltner
This department column highlights translation of research into healthcare quality practice. Achieving the highest quality in healthcare requires organizations to understand care delivery and to proactively mitigate risks in care delivery processes. The purpose of this article was to describe the process for using the failure modes and effects analysis process to provide evidentiary support and proactive risk mitigation for the establishment of a comprehensive vascular access team within an academic medical center...
January 2018: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
https://www.readbyqxmd.com/read/29288803/cardioprotection-after-acute-exposure-to-simulated-high-altitude-in-rats-role-of-nitric-oxide
#11
Pablo H La Padula, Melisa Etchegoyen, Analia Czerniczyniec, Barbara Piotrkowski, Silvia Lores Arnaiz, Jose Milei, Lidia E Costa
AIM: In previous studies, upregulation of NOS during acclimatization of rats to sustained hypobaric hypoxia was associated to cardioprotection, evaluated as an increased tolerance of myocardium to hypoxia/reoxygenation. The objective of the present work was to investigate the effect of acute hypobaric hypoxia and the role of endogenous NO concerning cardiac tolerance to hypoxia/reoxygenation under β-adrenergic stimulation. METHODS: Rats were submitted to 58.7 kPa in a hypopressure chamber for 48 h whereas their normoxic controls remained at 101...
December 27, 2017: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/29286780/order-parameters-and-color-flavor-center-symmetry-in-qcd
#12
Aleksey Cherman, Srimoyee Sen, Mithat Ünsal, Michael L Wagman, Laurence G Yaffe
Common lore suggests that N-color QCD with massive quarks has no useful order parameters that can be nontrivial at zero baryon density. However, such order parameters do exist when there are n_{f} quark flavors with a common mass and d≡gcd(n_{f},N)>1. These theories have a Z_{d} color-flavor center symmetry arising from intertwined color center transformations and cyclic flavor permutations. The symmetry realization depends on the temperature, baryon chemical potential, and value of n_{f}/N, with implications for conformal window studies and dense quark matter...
December 1, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29286203/docetaxel-cyclophosphamide-chemotherapy-in-older-patients-with-breast-cancer
#13
Lore Decoster, Christel Fontaine, Leen Vanacker, Denis Schallier, Jacques De Grève
No abstract text is available yet for this article.
December 29, 2017: Breast Journal
https://www.readbyqxmd.com/read/29277358/protocol-of-a-randomised-controlled-trial-regarding-the-effectiveness-of-fluoroscopy-guided-manual-lymph-drainage-for-the-treatment-of-breast-cancer-related-lymphoedema-effort-bcrl-trial
#14
Tessa De Vrieze, Lore Vos, Nick Gebruers, Wiebren A A Tjalma, Sarah Thomis, Patrick Neven, Ines Nevelsteen, An De Groef, Liesbeth Vandermeeren, Jean-Paul Belgrado, Nele Devoogdt
OBJECTIVES: Lymphoedema is a dreadful complication following breast cancer therapy. According to the International Society of Lymphology, the consensus treatment for breast cancer-related lymphoedema (BCRL) is the decongestive lymphatic therapy. This is a two-phase treatment and combines different treatment modalities including skin care, manual lymphatic drainage (MLD), compression therapy and exercise. However, the additional effect of MLD is debated since pooled data only demonstrated a limited non-significant additional value...
December 16, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29243146/correction-to-contraception-menstruation-and-sexuality-after-bariatric-surgery-a-prospective-cohort-study
#15
Julie Luyssen, Goele Jans, Annick Bogaerts, Dries Ceulemans, Christophe Matthys, Bart Van der Schueren, Matthias Lannoo, Johan Verhaeghe, Luc Lemmens, Lore Lannoo, Jill Shawe, Roland Devlieger
The spelling of author name Jill Shawe was incorrect in the original article. It is correct here.
December 14, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/29236245/-relevance-of-type-of-diagnosis-and-occupational-status-for-the-results-of-psychiatric-rehabilitation
#16
Friedrich Riffer, Manuel Sprung, Lore Streibl, Elmar Kaiser
OBJECTIVE: The specific effectiveness of psychiatric rehabilitation has been confirmed in numerous studies. Of particular interest is to what extend different results can be observed regarding the occupational status and type of mental illness of patients. Unemployment at the start of treatment is generally deemed to be a disadvantage for treatment outcome. Weaker treatment effects have also been reported for some types of mental illnesses, such as pain- und somatoform disorders. METHODS: Results from the evaluation of a sample of 2260 patients form the psychiatric rehabilitation clinic Gars am Kamp were analyzed, with regard to the occupational status and type of mental illness of patients...
December 13, 2017: Neuropsychiatrie: Klinik, Diagnostik, Therapie und Rehabilitation
https://www.readbyqxmd.com/read/29228393/quantifying-the-arousal-threshold-using-polysomnography-in-obstructive-sleep-apnea
#17
Scott A Sands, Philip I Terrill, Bradley A Edwards, Luigi Taranto Montemurro, Ali Azarbarzin, Melania Marques, Camila M de Melo, Stephen H Loring, James P Butler, David White, Andrew Wellman
Objectives: Precision medicine for obstructive sleep apnea (OSA) requires non-invasive estimates of each patient's pathophysiological "traits". Here we provide the first, automated technique to quantify the respiratory arousal threshold-defined as the level of ventilatory drive triggering arousal from sleep-using diagnostic polysomnographic signals in patients with OSA. Methods: Ventilatory drive preceding clinically-scored arousals was estimated from polysomnographic studies by fitting a respiratory control model (Terrill P et al...
November 9, 2017: Sleep
https://www.readbyqxmd.com/read/29212345/a-pilot-investigation-of-an-ios-based-app-for-toilet-training-children-with-autism-spectrum-disorder
#18
Daniel W Mruzek, Stephen McAleavey, Whitney A Loring, Eric Butter, Tristram Smith, Erin McDonnell, Lynne Levato, Courtney Aponte, Rebekah P Travis, Rachel E Aiello, Cora M Taylor, Jonathan W Wilkins, Patricia Corbett-Dick, Dianne M Finkelstein, Alyssa M York, Katherine Zanibbi
We developed an iOS-based app with a transmitter/disposable sensor and corresponding manualized intervention for children with autism spectrum disorder. The app signaled the onset of urination, time-stamped accidents for analysis, reminded parents to reinforce intervals of continence, provided a visual outlet for parents to communicate reinforcement, and afforded opportunity for timely feedback from clinicians. We compared this intervention with an intervention that uses standard behavioral treatment in a pilot randomized controlled trial of 33 children with autism spectrum disorder aged 3-6 years with urinary incontinence...
December 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29207669/breath-analysis-by-gas-chromatography-mass-spectrometry-and-electronic-nose-to-screen-for-pleural-mesothelioma-a-cross-sectional-case-control-study
#19
Kevin Lamote, Paul Brinkman, Lore Vandermeersch, Matthijs Vynck, Peter J Sterk, Herman Van Langenhove, Olivier Thas, Joris Van Cleemput, Kristiaan Nackaerts, Jan P van Meerbeeck
Rationale: Malignant pleural mesothelioma (MPM) is mainly caused by previous exposure to asbestos fibers and has a poor prognosis. Due to a long latency period between exposure and diagnosis, MPM incidence is expected to peak between 2020-2025. Screening of asbestos-exposed individuals is believed to improve early detection and hence, MPM management. Recent developments focus on breath analysis for screening since breath contains volatile organic compounds (VOCs) which reflect the cell's metabolism...
October 31, 2017: Oncotarget
https://www.readbyqxmd.com/read/29207231/-leading-characters-of-privacy-policies-informative-note-and-informed-consent
#20
EDITORIAL
Filippo Lorè
No abstract text is available yet for this article.
December 5, 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
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