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Severe adolescent headaches

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https://www.readbyqxmd.com/read/28402139/long-term-open-label-safety-study-of-edivoxetine-monotherapy-in-children-and-adolescents-with-attention-deficit-hyperactivity-disorder
#1
Emel Serap Monkul Nery, Mark Bangs, Peng Liu, Jonna Ahl, David Perahia
OBJECTIVE: The purpose of this study was to assess the long-term safety and tolerability of edivoxetine, a selective norepinephrine reuptake inhibitor, which was being developed as monotherapy in pediatric attention-deficit/hyperactivity disorder (ADHD). METHODS: This was an open-label study of edivoxetine once daily dosing (0.1-0.3 mg/kg) as treatment for ADHD in children (6-11 years) and adolescents (12-17 years) to assess safety for up to 5 years. The safety assessments included the incidence of adverse events, vital signs, electrocardiograms, laboratory tests, percentile changes in weight, height, and body mass index, and Tanner staging...
April 12, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28192568/early-performance-in-medicaid-accountable-care-organizations-a-comparison-of-oregon-and-colorado
#2
K John McConnell, Stephanie Renfro, Benjamin K S Chan, Thomas H A Meath, Aaron Mendelson, Deborah Cohen, Jeanette Waxmonsky, Dennis McCarty, Neal Wallace, Richard C Lindrooth
Importance: Several state Medicaid reforms are under way, but the relative performance of different approaches is unclear. Objective: To compare the performance of Oregon's and Colorado's Medicaid Accountable Care Organization (ACO) models. Design, Setting, and Participants: Oregon initiated its Medicaid transformation in 2012, supported by a $1.9 billion investment from the federal government, moving most Medicaid enrollees into 16 Coordinated Care Organizations, which managed care within a global budget...
April 1, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28160287/association-between-migraine-and-atopic-diseases-in-childhood-a-potential-protective-role-of-anti-allergic-drugs
#3
Camille Aupiais, Stephanie Wanin, Silvia Romanello, Daniele Spiri, Raffaella Moretti, Priscilla Boizeau, Davide Massano, Gian Vincenzo Zuccotti, Giovanni Crichiutti, Lakshmi Kanagarajah, Veronique Houdouin, Corinne Alberti, Luigi Titomanlio
BACKGROUND: Migraine is a common cause of headache in childhood. Several studies have investigated the association between migraine and atopic diseases, mostly in the adult population. OBJECTIVE: This study aimed to investigate this association in children. METHODS: A case-control study was conducted across 3 European tertiary care hospitals between June 2014 and August 2014. Cases (n = 229) were children aged 6-18 years consulting for a migraine episode...
April 2017: Headache
https://www.readbyqxmd.com/read/28141730/-footprints-in-the-bathroom-the-role-of-spirituality-in-patient-diagnosis
#4
Veronica Meneses, Douglas Vanderbilt, Linda Barnes, Marilyn Augustyn
Lucy is a 12-year-old Latina whose mother brought her to the pediatric clinic for help with her anxiety symptoms, "hearing voices," and episodes of "spacing out." Lucy did not cry at birth secondary to vocal cord paralysis and still has the tracheostomy performed at a few days of life. In addition to her neonatal intensive care unit stay, she has been hospitalized for pneumonia. Her mother says she is "sickly" and has a weak immune system due to her asthma symptoms. Lucy also experiences somatic complaints related to gastroesophageal reflux and constipation...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28122770/factor-structure-of-impact%C3%A2-in-adolescent-student-athletes
#5
Paul B Gerrard, Grant L Iverson, Joseph E Atkins, Bruce A Maxwell, Ross Zafonte, Philip Schatz, Paul D Berkner
OBJECTIVE: ImPACT(®) (Immediate Post-Concussion Assessment and Cognitive Testing) is a computerized neuropsychological screening battery, which is widely used to measure the acute effects of sport-related concussion and to monitor recovery from injury. This study examined the factor structure of ImPACT(®) in several samples of high school student athletes. We hypothesized that a 2-factor structure would be present in all samples. METHOD: A sample of 4,809 adolescent student athletes was included, and subgroups with a history of treatment for headaches or a self-reported history of learning problems or attention-deficit hyperactivity disorder were analyzed separately...
February 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28100071/neck-tongue-syndrome-a-systematic-review
#6
Amy A Gelfand, Hannah Johnson, Marc Ep Lenaerts, Jessica R Litwin, Charles De Mesa, Nikolai Bogduk, Peter J Goadsby
Objective Neck-Tongue syndrome (NTS) is characterized by brief attacks of neck or occipital pain, or both, brought out by abrupt head turning and accompanied by ipsilateral tongue symptoms. As the disorder is rare, we undertook a systematic review of the literature to identify all reported cases in order to phenotype clinically the disorder and subsequently inform clinical diagnostic criteria. Methods Two electronic databases were searched using the search term "neck tongue syndrome". All English language references were reviewed in full...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28099131/turner-syndrome-and-pituitary-adenomas-a-case-report-and-review-of-literature
#7
Tiffany Yeh, Angela Ganan Soto, Jose Bernardo Quintos, Lisa Swartz Topor
BACKGROUND: Turner syndrome (TS) is the most common sex chromosome abnormality in females, typically associated with primary amenorrhea and premature ovarian failure due to gonadal dysgenesis. The association of TS with hypopituitarism is an uncommon finding. The objective of the study was to describe an adolescent with TS with hypergonadotropic hypogonadism and subsequent hypogonadotropic hypogonadism. CASE PRESENTATION: A 16-year-old female with primary amenorrhea was diagnosed with TS based on karyotype 45,XO...
February 1, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28094022/a-case-report-of-an-adolescent-with-cluster-headaches-following-neck-trauma-coincidence-or-trigger
#8
Agnieszka Biedroń, Marek Kaciński, Małgorzata Steczkowska, Anna Świerczyńska
Posttraumatic headaches usually have tension-type or migraine-like characteristics. A correlation between head trauma and cluster headaches (CH) has been previously reported. CH in children are rare and require thorough differential diagnosis. We present an original case of a 15-year-old boy with cluster headaches associated with allodynia probably evoked by a neck trauma. Severe headache attacks started one month after neck trauma. At the beginning clinical presentation of our patient's headaches was very misleading...
March 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28093374/predictors-of-pharmacological-intervention-in-adolescents-with-protracted-symptoms-after-sports-related-concussion
#9
Shanti M Pinto, Maria F Twichell, Luke C Henry
BACKGROUND: Although recovery after concussion is spontaneous and typically occurs within 2-3 weeks, a subset of adolescents develop persistent symptoms after a sports-related concussion. Medications are frequently prescribed as part of a comprehensive treatment approach to alleviate these symptoms; however, there are no guidelines for prescription of pharmacologic therapy after concussion. OBJECTIVE: To investigate common factors that are associated with the use of medications (antiepileptic, antidepressant, neurostimulant, or sleeping medication) during recovery from a sports-related concussion...
January 14, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28068790/temporomandibular-disorders-old-ideas-and-new-concepts
#10
Thomas List, Rigmor Højland Jensen
Background Temporomandibular disorders (TMD) is an umbrella term for pain and dysfunction involving the masticatory muscles and the temporomandibular joints (TMJs). TMD is the most common orofacial pain condition. Its prominent features include regional pain in the face and preauricular area, limitations in jaw movement, and noise from the TMJs during jaw movements. TMD affects up to 15% of adults and 7% of adolescents. Chronic pain is the overwhelming reason that patients with TMD seek treatment. TMD can associate with impaired general health, depression, and other psychological disabilities, and may affect the quality of life of the patient...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28058729/role-of-the-attachment-style-in-determining-the-association-between-headache-features-and-psychological-symptoms-in-migraine-children-and-adolescents-an-analytical-observational-case-control-study
#11
Samuela Tarantino, Cristiana De Ranieri, Cecilia Dionisi, Valentina Gagliardi, Maria Francesca Paniccia, Alessandro Capuano, Roberto Frusciante, Martina Balestri, Federico Vigevano, Simonetta Gentile, Massimiliano Valeriani
OBJECTIVE: We aimed to study the role of attachment style on headache severity and psychological symptoms in migraineurs children/adolescents. Moreover, we investigated the association between attachment style, migraine severity, and psychological symptoms. BACKGROUND: Attachment theory suggests that early interpersonal relationships may be important determinants of psychopathology and pain management. In particular, individuals with insecure attachment styles have been shown to experience more pain than people with secure attachment style...
February 2017: Headache
https://www.readbyqxmd.com/read/28027810/first-in-human-safety-and-immunogenicity-investigations-of-three-adjuvanted-reduced-dose-inactivated-poliovirus-vaccines-ipv-al-ssi-compared-to-full-dose-ipv-vaccine-ssi-when-given-as-a-booster-vaccination-to-adolescents-with-a-history-of-ipv-vaccination-at
#12
Line M Lindgren, Pernille N Tingskov, Annette H Justesen, Bettina S Nedergaard, Klaus J Olsen, Lars V Andreasen, Ingrid Kromann, Charlotte Sørensen, Jes Dietrich, Birgit Thierry-Carstensen
BACKGROUND: There is a demand of affordable IPV in the World. Statens Serum Institut (SSI) has developed three reduced dose IPV formulations adsorbed to aluminium hydroxide; 1/3 IPV-Al, 1/5 IPV-Al and 1/10 IPV-Al SSI, and now report the results of the first investigations in humans. METHODS: 240 Danish adolescents, aged 10-15years, and childhood vaccinated with IPV were booster vaccinated with 1/3 IPV-Al, 1/5 IPV-Al, 1/10 IPV-Al or IPV Vaccine SSI. The booster effects (GMTRs) of the three IPV-Al SSI were compared to IPV Vaccine SSI, and evaluated for non-inferiority...
January 23, 2017: Vaccine
https://www.readbyqxmd.com/read/28009630/sex-differences-in-the-efficacy-of-psychological-therapies-for-the-management-of-chronic-and-recurrent-pain-in-children-and-adolescents-a-systematic-review-and-meta-analysis
#13
Katelynn E Boerner, Christopher Eccleston, Christine T Chambers, Edmund Keogh
Sex differences in chronic pain are reported to emerge during adolescence, although it is unclear if this includes responses to treatment. We conducted a meta-analysis to examine whether sex differences were present on outcome variables at pre-treatment, and whether the efficacy of psychological therapies for pediatric chronic pain differs between boys and girls at post-treatment and follow-up time points. Searches were conducted, extending two existing Cochrane reviews of randomized-controlled trials examining the efficacy of psychological therapies for chronic and recurrent pain in children and adolescents...
December 15, 2016: Pain
https://www.readbyqxmd.com/read/27984491/sex-differences-in-the-efficacy-of-psychological-therapies-for-the-management-of-chronic-and-recurrent-pain-in-children-and-adolescents-a-systematic-review-and-meta-analysis
#14
Katelynn E Boerner, Christopher Eccleston, Christine T Chambers, Edmund Keogh
Sex differences in chronic pain are reported to emerge during adolescence, although it is unclear if this includes responses to treatment. We conducted a meta-analysis to examine whether sex differences were present on outcome variables at pre-treatment, and whether the efficacy of psychological therapies for pediatric chronic pain differs between boys and girls at post-treatment and follow-up time points. Searches were conducted, extending two existing Cochrane reviews of randomized-controlled trials examining the efficacy of psychological therapies for chronic and recurrent pain in children and adolescents...
December 15, 2016: Pain
https://www.readbyqxmd.com/read/27856068/efficacy-of-transdiagnostic-cognitive-behavioral-group-therapy-for-anxiety-disorders-and-headache-in-adolescents
#15
Pragya Sharma, Manju Mehta, Rajesh Sagar
Anxiety disorders and headache are both among the most prevalent disorders among adolescents. Although cognitive behavioral therapy (CBT) has proved its efficacy with each of these disorders individually, there are several barriers to its utilization, including cost, gaps in knowledge about treatment delivery and modes, and its utility with comorbid disorders. The current study examined the comparative efficacy of a 12 week TCBT Group treatment (n=32) versus treatment as usual group (n=31) (TAU) in adolescents with anxiety disorders and headache in a north Indian hospital based setting...
November 9, 2016: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/27788026/trial-of-amitriptyline-topiramate-and-placebo-for-pediatric-migraine
#16
RANDOMIZED CONTROLLED TRIAL
Scott W Powers, Christopher S Coffey, Leigh A Chamberlin, Dixie J Ecklund, Elizabeth A Klingner, Jon W Yankey, Leslie L Korbee, Linda L Porter, Andrew D Hershey
BACKGROUND: Which, medication, if any, to use to prevent the headache of pediatric migraine has not been established. METHODS: We conducted a randomized, double-blind, placebo-controlled trial of amitriptyline (1 mg per kilogram of body weight per day), topiramate (2 mg per kilogram per day), and placebo in children and adolescents 8 to 17 years of age with migraine. Patients were randomly assigned in a 2:2:1 ratio to receive one of the medications or placebo. The primary outcome was a relative reduction of 50% or more in the number of headache days in the comparison of the 28-day baseline period with the last 28 days of a 24-week trial...
January 12, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/27766482/treatment-adherence-and-illness-self-management-introduction-to-the-special-issue
#17
M Bryant Howren, Jeffrey S Gonzalez
The current issue is devoted broadly to research on treatment adherence and chronic illness self-management behavior. As the prevalence of chronic illness increases, the pervasive problem of treatment nonadherence is increasingly viewed as having a major impact on treatment outcomes, public health and healthcare costs, making this issue particularly timely. Sixteen articles spanning an array of topics are presented; articles include empirical studies, statistical simulations, systematic reviews, and theoretical commentaries...
October 20, 2016: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/27731894/patterns-of-use-of-peripheral-nerve-blocks-and-trigger-point-injections-for-pediatric-headache-results-of-a-survey-of-the-american-headache-society-pediatric-and-adolescent-section
#18
Christina L Szperka, Amy A Gelfand, Andrew D Hershey
OBJECTIVE: To describe current patterns of use of nerve blocks and trigger point injections for treatment of pediatric headache. BACKGROUND: Peripheral nerve blocks are often used to treat headaches in adults and children, but the available studies and practice data from adult headache specialists have shown wide variability in diagnostic indications, sites injected, and medication(s) used. The purpose of this study was to describe current practice patterns in the use of nerve blocks and trigger point injections for pediatric headache disorders...
November 2016: Headache
https://www.readbyqxmd.com/read/27661197/chronic-headaches-after-a-concussion-in-an-obese-16-year-old-girl
#19
Maya Kumar, Sheila Gahagan, Bretten Pickering, Jeffrey Gold, Martin T Stein
Jennifer is a 16-year-old Latina girl who is new to your practice. During her first well visit, she mentions that she has had daily headaches for 2 years. They began after sustaining a concussion in a car accident. Typically, her headaches are bilateral and "squeezing"; they occur in the afternoons and last for a few hours. Her concussion also resulted in depressed mood, which has improved over time.When you ask if her headaches have changed recently, she says that they have been worse for the last few days...
November 2016: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/27638083/vertigo-and-dizziness-in-children
#20
K Jahn
Vertigo and dizziness of at least moderate severity occur in >5% of school-aged children and cause considerable restrictions in participation in school and leisure activity. More than 50% of dizzy children also have headache. Vestibular migraine and benign paroxysmal vertigo as a migraine precursor are the most common diagnoses in dizziness clinics for children and adolescents. They account for 30-60% of diagnoses. Other common causes are somatoform, orthostatic, or posttraumatic dizziness. All other disorders that are known to cause vertigo and dizziness in adults also occur in children, but incidence rates are usually lower...
2016: Handbook of Clinical Neurology
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