keyword
MENU ▼
Read by QxMD icon Read
search

Hpv

keyword
https://www.readbyqxmd.com/read/29150417/using-facebook-to-recruit-young-australian-men-into-a-cross-sectional-human-papillomavirus-study
#1
Roopa Das, Dorothy A Machalek, Edmund G Molesworth, Suzanne M Garland
BACKGROUND: Young men can be difficult to engage in health research using traditional methods of recruitment. Social networking sites are increasingly being used to recruit participants into health research, due to their cost effectiveness, overall generalizability, and wide reach. OBJECTIVE: The aim of this study was to determine the feasibility of using Facebook to recruit young Australian men into a human papillomavirus (HPV) prevalence study. METHODS: We recruited male permanent residents of Australia, aged 18 to 35 years, into the HPV in Young Males (HYM) study through targeted advertising placed on Facebook...
November 17, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29150210/a-behavioral-economics-approach-to-the-failed-hpv-vaccination-program-in-japan
#2
Asami Yagi, Yutaka Ueda, Tadashi Kimura
No abstract text is available yet for this article.
November 15, 2017: Vaccine
https://www.readbyqxmd.com/read/29149907/mapping-evidence-on-the-distribution-of-human-papillomavirus-related-cancers-in-sub-saharan-africa-scoping-review-protocol
#3
Bridget K M Lekoane, Tivani P Mashamba-Thompson, Themba G Ginindza
BACKGROUND: Despite the introduction of HPV vaccines, the incidence of HPV-related cancers (cervical, penile, anal, vulvar, vagina, head, and neck) in sub-Saharan Africa has been rising. The increasing incidence of these HPV-related cancers has been attributed to changes in lifestyle-related risk factors, most notably sexual behavior. The main objective of this study is to map evidence on the distribution of HIV-related cancers in sub-Saharan Africa (SSA). METHODS AND ANALYSIS: We will conduct a scoping review to explore, describe, and map literature on the distribution of HPV-related cancers in sub-Saharan Africa...
November 17, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/29149434/enhancement-of-therapeutic-dna-vaccine-potency-by-melatonin-through-inhibiting-vegf-expression-and-induction-of-antitumor-immunity-mediated-by-cd8-t-cells
#4
Sanaz Baghban Rahimi, Alireza Mohebbi, Gelareh Vakilzadeh, Peyvand Biglari, Soodeh Razeghi Jahromi, Seyed Reza Mohebi, Sadegh Shirian, Ali Gorji, Amir Ghaemi
To be effective, therapeutic cancer vaccines should stimulate both an effective cell-mediated and a robust cytotoxic CD8+ T-cell response against human papillomavirus (HPV)-infected cells to treat the pre-existing tumors and prevent potential future tumors. In this study, the therapeutic experiments were designed in order to evaluate antitumor effect against the syngeneic TC-1 tumor model. The anti-tumor efficacy of a HPV-16 E7 DNA vaccine adjuvanted with melatonin (MLT) was evaluated in a C57BL/6 mouse tumor model by measuring tumor growth post vaccination and the survival rate of tumor-bearing mice, analyzing the specific lymphocyte proliferation responses in control and vaccinated mice by MTT assay...
November 17, 2017: Archives of Virology
https://www.readbyqxmd.com/read/29145765/epidemiological-and-treatment-related-factors-contribute-to-improved-outcome-of-oropharyngeal-squamous-cell-carcinoma-in-finland
#5
Lauri Jouhi, Elina Halme, Heikki Irjala, Kauko Saarilahti, Petri Koivunen, Matti Pukkila, Jaana Hagström, Caj Haglund, Paula Lindholm, Pasi Hirvikoski, Samuli Vaittinen, Anna Ellonen, Jukka Tikanto, Henry Blomster, Jussi Laranne, Reidar Grénman, Antti Mäkitie, Timo Atula
BACKGROUND: Treatment for oropharyngeal squamous cell carcinoma (OPSCC) has changed, as the proportion of human papilloma virus (HPV)-related disease has increased. We evaluated nationwide information on its management and outcome during the treatment paradigm change period. METHODS: We included all patients diagnosed and treated for OPSCC at the five Finnish university hospitals from 2000 to 2009. Patient records and pathology registries provided the clinicopathological data...
November 17, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/29145648/relative-performance-of-hpv-and-cytology-components-of-cotesting-in-cervical-screening
#6
Mark Schiffman, Walter K Kinney, Li C Cheung, Julia C Gage, Barbara Fetterman, Nancy E Poitras, Thomas S Lorey, Nicolas Wentzensen, Brian Befano, John Schussler, Hormuzd A Katki, Philip E Castle
Background: The main goal of cervical screening programs is to detect and treat precancer before cancer develops. Human papillomavirus (HPV) testing is more sensitive than cytology for detecting precancer. However, reports of rare HPV-negative, cytology-positive cancers are motivating continued use of both tests (cotesting) despite increased testing costs. Methods: We quantified the detection of cervical precancer and cancer by cotesting compared with HPV testing alone at Kaiser Permanente Northern California (KPNC), where 1 208 710 women age 30 years and older have undergone triennial cervical cotesting since 2003...
November 14, 2017: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29145573/human-papillomavirus-hpv-and-somatic-egfr-mutations-are-essential-mutually-exclusive-oncogenic-mechanisms-for-inverted-sinonasal-papillomas-and-associated-sinonasal-squamous-cell-carcinomas
#7
A M Udager, J B McHugh, C M Goudsmit, H C Weigelin, M S Lim, K S J Elenitoba-Johnson, B L Betz, T E Carey, N A Brown
Background: Inverted sinonasal papilloma (ISP) is a locally aggressive neoplasm often associated with sinonasal squamous cell carcinoma (SNSCC). While the etiology of ISP is not well understood, human papillomavirus (HPV) has been detected in a subset of cases. Our group recently identified activating somatic EGFR mutations in the majority of ISP and ISP-associated SNSCC. However, the relationship between EGFR mutations and HPV infection has not been explored. Patients and Methods: We evaluated 58 ISP and 22 ISP-associated SNSCC (including 13 patients with matched ISP/SNSCC samples), as well as 14 SNSCC without clinical or pathologic evidence of an associated ISP...
November 14, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29145543/association-of-ipilimumab-with-safety-and-antitumor-activity-in-women-with-metastatic-or-recurrent-human-papillomavirus-related-cervical-carcinoma
#8
Stephanie Lheureux, Marcus O Butler, Blaise Clarke, Mihaela C Cristea, Lainie P Martin, Katia Tonkin, Gini F Fleming, Anna V Tinker, Hal W Hirte, Daliah Tsoref, Helen Mackay, Neesha C Dhani, Prafull Ghatage, Johanne Weberpals, Stephen Welch, Nhu-An Pham, Vinicius Motta, Valentin Sotov, Lisa Wang, Katherine Karakasis, Smitha Udagani, Suzanne Kamel-Reid, Howard Z Streicher, Patricia Shaw, Amit M Oza
Importance: Based on evidence of human papillomavirus (HPV)-induced immune evasion, immunotherapy may be an attractive strategy in cervical cancer. Ipilimumab is a fully humanized monoclonal antibody that blocks cytotoxic T-lymphocyte antigen-4 (CTLA-4), which acts to downregulate the T-cell immune response. Objective: To assess the safety and antitumor activity of ipilimumab in recurrent cervical cancer. Design, Setting, and Participants: A multicenter trial was designed for patients with metastatic cervical cancer (squamous cell carcinoma or adenocarcinoma) with measurable disease and progression after at least 1 line of platinum chemotherapy...
November 16, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/29144557/penile-warty-mucoepidermoid-carcinoma-with-features-of-stratified-mucin-producing-intraepithelial-lesion-and-invasive-stratified-mucin-producing-carcinoma
#9
Kenji Yorita, Naoto Kuroda, Takushi Naroda, Masato Tamura, Chisato Ohe, Mukul Divatia, Mahul B Amin, Antonio L Cubilla, Dimitry V Kazakov, Ondrej Hes, Michael Michal, Michal Michal
AIMS: Stratified mucin-producing intraepithelial lesion (SMILE) and invasive stratified mucin-producing carcinoma (ISMC) are recently described cervical and penile lesions. We report an unusual case of mixed variant of penile squamous cell carcinomas with warty, usual and mucoepidermoid SMILE/ISMC features. METHODS AND RESULTS: A 62-year-old Japanese man had a glans penis lesion of one and a half years duration, suggesting malignancy. Partial penectomy and left inguinal lymphadenectomy were performed...
November 16, 2017: Histopathology
https://www.readbyqxmd.com/read/29144546/presence-of-infection-and-analysis-of-hpv-subtypes-in-girls-younger-than-9-years-old-attended-at-a-referral-service-in-esp%C3%A3-rito-santo-brazil
#10
Mariana Penha De Nadai Sartori, Lidiane Pignaton Agostini, Thaís Tristão Tovar, Raquel Silva Dos Reis, Raquel Spinassé Dettogni, Eldamária de Vargas Wolfgramm Dos Santos, Antônio Chambô Filho, Iúri Drumond Louro
PURPOSE: Human papillomavirus is found in adults and adolescents and is associated with genital warts and cervical cancer. However, it has been detected in girls younger than 10 years old. Currently, there are no prevention methods for this age group, since it is not considered a risk group. The aim of this study was to evaluate the presence of infection and HPV subtype in girls under 9 years old attended at a referral service in the State of Espírito Santo, Brazil. METHODS: Forty-three girls younger than 9 years old had gynecological brush samples collected from vulval and perineal/anal regions...
November 16, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/29144223/no-touch-disinfection-methods-to-decrease-multidrug-resistant-organism-infections-a-systematic-review-and-meta-analysis
#11
Alexandre R Marra, Marin L Schweizer, Michael B Edmond
BACKGROUND Recent studies have shown that using no-touch disinfection technologies (ie, ultraviolet light [UVL] or hydrogen peroxide vapor [HPV] systems) can limit the transmission of nosocomial pathogens and prevent healthcare-associated infections (HAIs). To investigate these findings further, we performed a systematic literature review and meta-analysis on the impact of no-touch disinfection methods to decrease HAIs. METHODS We searched PubMed, CINAHL, CDSR, DARE and EMBASE through April 2017 for studies evaluating no-touch disinfection technology and the nosocomial infection rates for Clostridium difficile, methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and other multidrug-resistant organisms (MDROs)...
November 16, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29143102/diagnostic-performance-of-hpv-e6-e7-mrna-assay-for-detection-of-cervical-high-grade-intraepithelial-neoplasia-and-cancer-among-women-with-ascus-papanicolaou-smears
#12
Chenchen Ren, Yuanhang Zhu, Li Yang, Xiaoan Zhang, Ling Liu, Chunying Ren
PURPOSE: The aim of this study was to investigate the clinical performance of high risk (HR) HPV E6/E7 mRNA assay in detecting cervical high-grade intraepithelial neoplasia and cancer among women with atypical squamous cells of undetermined significance (ASCUS) Papanicolaou (Pap) smears. METHODS: A total of 160 patients with ASCUS who underwent HR-HPV DNA assay, HR-HPV E6/E7 mRNA assay and colposcopy biopsy at Third Affiliated Hospital of Zhengzhou University, China, from December 2015 to March 2017, were enrolled...
November 15, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29143101/candidate-biomarkers-in-the-cervical-vaginal-fluid-for-the-self-diagnosis-of-cervical-precancer
#13
REVIEW
Xaveer Van Ostade, Martin Dom, Wiebren Tjalma, Geert Van Raemdonck
PURPOSE: Despite improvement in vaccines against human papilloma virus (HPV), the causative agent of cervical cancer, screening women for cervical precancer will remain indispensable in the coming 30-40 years. A simple test that could be performed at home or at a doctor's practice and that informs the woman whether she is at risk would significantly help make a broader group of patients who aware that they need medical treatment. Cervical vaginal fluid (CVF) is a body fluid that is very well suited for such a test...
November 15, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29142587/factors-associated-with-the-high-prevalence-of-oesophageal-cancer-in-western-kenya-a-review
#14
REVIEW
Gabriel Kigen, Naftali Busakhala, Zipporah Kamuren, Hillary Rono, Wilfred Kimalat, Evangeline Njiru
Oesophageal carcinoma (OC) is highly prevalent in Western Kenya especially among the members of the Kalenjin community who reside in the Northern and Southern areas of the Rift Valley. Previous authors have suggested potential association of environmental and genetic risk factors with this high prevalence. The environmental factors that have been suggested include contamination of food by mycotoxins and/or pesticides, consumption of traditional alcohol (locally referred to "Busaa" and "Chan'gaa"), use of fermented milk ("Mursik"), poor diet, tobacco use and genetic predisposition...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/29142126/hpv-replication-regulation-by-acetylation-of-a-conserved-lysine-in-the-e2-protein
#15
Yanique Thomas, Elliot J Androphy
The Papillomavirus (PV) E2 protein is a sequence specific DNA binding protein that recruits cellular factors to its genome in infected epithelial cells. E2 also binds to and loads the viral E1 DNA helicase at the origin of replication. Post-translational modifications (PTMs) of PV E2 have been identified as potential regulators E2 functions. We recently reported lysine (K) 111 as a target of p300 acetylation in bovine (B)PV. The di-lysines at 111 and 112 are conserved in almost all papillomaviruses. We pursued a mutational approach to query the functional significance of lysine in human (H)PV E2...
November 15, 2017: Journal of Virology
https://www.readbyqxmd.com/read/29141014/prevalence-and-risk-factors-of-anal-human-papillomavirus-infection-among-hiv-negative-men-who-have-sex-with-men-in-urumqi-city-of-xinjiang-uyghur-autonomous-region-china
#16
Tian Tian, Peierdun Mijiti, Huang Bingxue, Zhang Fadong, Abidan Ainiwaer, Sang Guoyao, Zhang Zhanlin, Yeledan Mahan, Tuo Xiaoqin, Gong Zheng, Dai Jianghong
BACKGROUND: Infection with human papillomavirus (HPV) is the most common sexually transmitted infection among men who have sex with men (MSM). Study on prevalence and risk factors of anal HPV infection among HIV-negative MSM in Northwestern China was rare. METHODS: We performed a cross-sectional study of HPV prevalence using anal swab specimens among HIV-negative MSM in Urumqi city of Xinjiang Uyghur Autonomous Region, China between April 1st and October 30th in 2016...
2017: PloS One
https://www.readbyqxmd.com/read/29140880/high-risk-human-papillomavirus-determination-in-formalin-fixed-paraffin-embedded-cervical-tissue-using-the-roche-cobas-4800-system-a-comparative-study-with-liquid-based-cytology
#17
Juan C Tardío, Olivia Cambero, Carolina Sánchez-Estévez, Ana B Sánchez-García, Fernando Angulo, Amalia Moreno
Roche cobas 4800 human papillomavirus (HPV) test is an automated real-time polymerase chain reaction-based system that allows the simultaneous detection of 14 human papillomavirus high-risk (HR-HPV) genotypes. This test is Food and Drug Administration approved since 2011 for HPV determination in liquid-based cytologic samples, but a clinically validated technique for formalin-fixed, paraffin-embedded (FFPE) tissue specimens is presently not commercially available. In our laboratory, we have developed an HPV detection procedure in FFPE tissue by cobas 4800 HPV test...
November 14, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29140439/bivalent-vaccine-effectiveness-against-type-specific-hpv-positivity-evidence-for-cross-protection-against-oncogenic-types-among-dutch-sti-clinic-visitors
#18
Petra J Woestenberg, Audrey J King, Birgit H B van Benthem, Robine Donken, Suzan Leussink, Fiona R M van der Klis, Hester E de Melker, Marianne A B van der Sande, Christian J P A Hoebe, Johannes A Bogaards
Background: Observational post-marketing studies are important to assess vaccine effectiveness (VE). We estimated VE from the bivalent human papillomavirus (HPV) vaccine against HPV positivity of vaccine and non-vaccine types in a high-risk population. Methods: We included all vaccine-eligible women from the PASSYON study, a biennial cross-sectional survey in Dutch sexually transmitted infection clinics. Vaginal swabs were analyzed using a PCR-based assay (SPF10-LiPA25) able to detect the 12 high-risk HPV (hrHPV) types 16/18/31/33/35/39/45/51/52/56/58/59...
November 11, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29140428/hpv-negative-but-not-hpv-positive-oropharyngeal-carcinomas-induce-fibroblasts-to-support-tumour-invasion-through-micro-environmental-release-of-hgf-and-il-6
#19
Robert Bolt, Bernadette Foran, Craig Murdoch, Daniel W Lambert, Sally Thomas, Keith D Hunter
Human papillomavirus (HPV) infection is causally related to a subset of oropharyngeal carcinomas (OPC) and is linked to a more favourable prognosis compared to HPV-negative OPC. The mechanisms underlying this effect on prognosis are not fully understood, but interactions with the tumour microenvironment may be pivotal. Here, we investigated the role of the tumour microenvironment in HPV-positive compared to HPV-negative cancer using 2D and 3D modelling of OPC interactions with stromal fibroblasts. HPV-negative, but not HPV-positive, OPC-derived cell lines induced a rapid fibroblast secretory response that supported 2D cancer cell migration and invasion in vitro...
November 13, 2017: Carcinogenesis
https://www.readbyqxmd.com/read/29138774/exploring-the-effect-of-substituent-in-the-hydrazone-ligand-of-a-family-of-%C3%AE-oxidodivanadium-v-hydrazone-complexes-on-structure-dna-binding-and-anticancer-activity
#20
Debashis Patra, Subhabrata Paul, Indira Majumder, Nayim Sepay, Sachinath Bera, Rita Kundu, Michael G B Drew, Tapas Ghosh
The reaction of 2-hydroxybenzoylhydrazine (H2bh) separately with equimolar amounts of [V(IV)O(aa)2] and [V(IV)O(ba)2] in CHCl3 afforded the complexes [VO3(HL(1))2] (1) and [VO3(HL(2))2] (2) respectively in good to excellent yield ((HL(1))(2-) and (HL(2))(2-) represent respectively the dianionic form of 2-hydroxybenzoylhydrazones of acetylacetone (H3L(1)) and benzoylacetone (H3L(2)) (general abbreviation H3L)). From X-ray structure analysis, the V(V)-O-V(V) angle was found to be ∼115° and 180° in 1 and 2 respectively...
November 15, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
keyword
keyword
3910
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"