keyword
https://read.qxmd.com/read/38479924/red-and-processed-meat-intake-and-risk-of-cardiovascular-disease-a%C3%A2-two-sample-mendelian-randomization-study
#21
JOURNAL ARTICLE
Bing Hu, Xin He, Hao Sun, Yongyi Hu, Fei Li, Yanxiang Sun, Jie Sun, Li Feng
BACKGROUND & AIMS: Previous observational studies have yielded inconsistent findings regarding associations between red/processed meat intake and the risk of cardiovascular disease (CVD). Some studies have suggested positive relationships, while others have demonstrated no significant associations. However, causal effects remain uncertain. This 2023 Mendelianrandomization (MR) study investigated the causal relationship between red and processed meat (porkmeat, mutton meat, beef meat)intake and CVD risk by analyzing summary data from the UK Biobank (exposure), CARDIoGRAMplusC4D (coronary artery disease [CAD]), MEGASTROKE (stroke), Nielsen et al...
April 2024: Clinical Nutrition ESPEN
https://read.qxmd.com/read/38479438/carotid-artery-stenosis-as-a-predictor-for-stroke-following-transcatheter-aortic-valve-implantation
#22
JOURNAL ARTICLE
Leonard Taube, Atsushi Sugiura, Arthur Hartmann, Christian Schaefer, Marwan Hamiko, Sebastian Zimmer, Georg Nickenig, Nadjib Schahab
Stroke remains a clinical risk in the long-term follow-up of patients after transcatheter aortic valve implantation (TAVI). We aimed to investigate the association between existing carotid artery stenosis (CS) and the risk of stroke after TAVI. The study participants were consecutive patients who underwent TAVI between 2008 and 2020 and were screened for CS at baseline and at the 30-day follow-up. Hemodynamically relevant CS was defined as a reduction of the carotid artery caliber by >50% in relation to the distal segment...
March 13, 2024: Angiology
https://read.qxmd.com/read/38479035/predictive-model-for-the-risk-of-hemorrhagic-transformation-after-rt-pa-intravenous-thrombolysis-in-patients-with-acute-ischemic-stroke-a-systematic-review-and-meta-analysis
#23
REVIEW
Kelong Zhong, Xuemei An, Yun Kong, Zhu Chen
OBJECTIVE: To systematically review the risk prediction model of Hemorrhages Transformation (HT) after intravenous thrombolysis in patients with Acute Ischemic Stroke (AIS). METHODS: Web of Science, The Cochrane Library, PubMed, Embase, CINAHL, CNKI, CBM, WanFang, and VIP were searched from inception to February 25, 2023 for literature related to the risk prediction model for HT after thrombolysis in AIS. RESULTS: A total of 17 included studies contained 26 prediction models, and the AUC of all models at the time of modeling ranged from 0...
March 7, 2024: Clinical Neurology and Neurosurgery
https://read.qxmd.com/read/38478534/atrial-fibrillation-in-middle-aged-athletes-impact-on-left-atrial-ventricular-and-exercise-performance
#24
JOURNAL ARTICLE
Emily Vecchiarelli, Robert F Bentley, Kim A Connelly, Paul Dorian, Andrew Yan, Susanna Mak, Zion Sasson, Jack M Goodman
High volume endurance training may increase the risk of paroxysmal atrial fibrillation (AF) in middle-aged athletes. Limited data are available describing the cardiovascular phenotype of middle-aged endurance athletes, or the impact of AF on atrial function and exercise performance performed in sinus rhythm. The purpose of this study was to characterize LA phasic function at rest and during exercise in athletes with paroxysmal AF, and to determine its impact on exercise performance. Fifteen endurance trained males (EA) (56 ± 5 years) without AF and 14 endurance trained males with paroxysmal AF (EA-AF) (55 ± 8 years) underwent echocardiography during cycle-ergometry at light and moderate intensities...
2024: PloS One
https://read.qxmd.com/read/38478165/cryoballoon-pulmonary-vein-isolation-as-first-line-treatment-of-typical-atrial-flutter-long-term-outcomes-of-the-craft-trial
#25
JOURNAL ARTICLE
Peter Calvert, Wern Yew Ding, Moloy Das, Lilith Tovmassian, Muzahir H Tayebjee, Guy Haywood, Claire A Martin, Kim Rajappan, Matthew G D Bates, Ian Peter Temple, Tobias Reichlin, Zhong Chen, Richard N Balasubramaniam, Christian Sticherling, Christina Ronayne, Nichola Clarkson, Maureen Morgan, Janet Barton, Ian Kemp, Saagar Mahida, Dhiraj Gupta
BACKGROUND: CRAFT was an international, multicentre, randomised controlled trial across 11 sites in the United UK and Switzerland. Given the evidence that pulmonary vein triggers may be responsible for atrial flutter (AFL) as well as atrial fibrillation (AF), we hypothesised that cryoballoon pulmonary vein isolation (PVI) would provide greater symptomatic arrhythmia reduction than cavotricuspid isthmus (CTI) ablation, whilst also reducing the subsequent burden of AF. Twelve-month outcomes were previously reported...
March 13, 2024: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://read.qxmd.com/read/38477908/cardiovascular-significance-and-genetics-of-epicardial-and-pericardial-adiposity
#26
JOURNAL ARTICLE
Joel T Rämö, Shinwan Kany, Cody R Hou, Samuel F Friedman, Carolina Roselli, Victor Nauffal, Satoshi Koyama, Juha Karjalainen, Mahnaz Maddah, Aarno Palotie, Patrick T Ellinor, James P Pirruccello
IMPORTANCE: Epicardial and pericardial adipose tissue (EPAT) has been associated with cardiovascular diseases such as atrial fibrillation or flutter (AF) and coronary artery disease (CAD), but studies have been limited in sample size or drawn from selected populations. It has been suggested that the association between EPAT and cardiovascular disease could be mediated by local or paracrine effects. OBJECTIVE: To evaluate the association of EPAT with prevalent and incident cardiovascular disease and to elucidate the genetic basis of EPAT in a large population cohort...
March 13, 2024: JAMA Cardiology
https://read.qxmd.com/read/38477853/lights-and-shadows-on-left-atrial-appendage-occlusion-mind-the-gap-in-knowledge-and-think-twice-on-long-term-outcomes
#27
JOURNAL ARTICLE
Luca Dell'Angela, Gian Luigi Nicolosi
Ischemic stroke prevention represents a crucial concern in health systems, being associated with high morbidity and mortality. Atrial fibrillation is associated with 15-20% of ischemic strokes, in the presence of thrombus in the left atrial appendage in 90% of patients with nonvalvular atrial fibrillation. Oral anticoagulation represents the standard of care. However, left atrial appendage occlusions have been developed for selected patients with nonvalvular atrial fibrillation. With regard to the latter, particularly, some important concerns have been raised on the selection of patients potentially amenable to the procedure, seemingly emphasizing a gap in knowledge, real-life clinical practice, and current management guidelines...
March 5, 2024: Journal of Cardiovascular Medicine
https://read.qxmd.com/read/38477017/should-left-atrial-appendage-closure-be-considered-in-resistant-left-atrial-appendage-thrombus-cases-former-foe-new-ally
#28
JOURNAL ARTICLE
Ahmet Hakan Ates, Ahmet Kivrak, Ugur Nadir Karakulak, Cem Coteli, Hikmet Yorgun, Mehmet Levent Sahiner, Ergun Barıs Kaya, Kudret Aytemir
BACKGROUND: The study explores left atrial appendage closure (LAAC) as a safe and effective alternative to anticoagulation for atrial fibrillation (AF) patients at high bleeding risk. Complications, such as cardioembolic events due to left atrial appendage thrombus (LAAT), highlight the need for alternative stroke prevention strategies. AIMS: This research assesses LAAC's safety and efficacy in patients with LAAT, aiming to offer valuable insights into its potential as a viable option for stroke prevention in such cases...
March 13, 2024: Pacing and Clinical Electrophysiology: PACE
https://read.qxmd.com/read/38475752/the-optimal-antithrombotic-strategy-for-post-stroke-patients-with-atrial-fibrillation-and-extracranial-artery-stenosis-a-nationwide-cohort-study
#29
JOURNAL ARTICLE
Chuan-Tsai Tsai, Yi-Hsin Chan, Jo-Nan Liao, Tzeng-Ji Chen, Gregory Y H Lip, Shih-Ann Chen, Tze-Fan Chao
BACKGROUND: In post-stroke atrial fibrillation (AF) patients who have indications for both oral anticoagulant (OAC) and antiplatelet agent (AP), e.g., those with carotid artery stenosis, there is debate over the best antithrombotic strategy. We aimed to compare the risks of ischemic stroke, composite of ischemic stroke/major bleeding and composite of ischemic stroke/intracranial hemorrhage (ICH) between different antithrombotic strategies. METHODS: This study included post-stroke AF patients with and without extracranial artery stenosis (ECAS) (n = 6390 and 28,093, respectively) identified from the Taiwan National Health Insurance Research Database...
March 13, 2024: BMC Medicine
https://read.qxmd.com/read/38475234/sensor-based-measurement-method-to-support-the-assessment-of-robot-assisted-radiofrequency-ablation
#30
JOURNAL ARTICLE
Hilda Zsanett Marton, Pálma Emese Inczeffy, Zsuzsanna Kis, Attila Kardos, Tamás Haidegger
Digital surgery technologies, such as interventional robotics and sensor systems, not only improve patient care but also aid in the development and optimization of traditional invasive treatments and methods. Atrial Fibrillation (AF) is the most common cardiac arrhythmia with critical clinical relevance today. Delayed intervention can lead to heart failure, stroke, or sudden cardiac death. Although many advances have been made in the field of radiofrequency (RF) catheter ablation (CA), it can be further developed by incorporating sensor technology to improve its efficacy and safety...
March 6, 2024: Sensors
https://read.qxmd.com/read/38471651/variation-and-disparity-in-awareness-of-atrial-fibrillation-in-china-a-national-cross-sectional-study
#31
JOURNAL ARTICLE
Shaobo Shi, Qingyan Zhao, Gang Wu, Hong Yan, Bin Yu, Qiangsun Zheng, Yigang Li, Liangrong Zheng, Yiqiang Yuan, Jingquan Zhong, Jian Xu, Yanqing Wu, Jing Xu, Lin Chen, Shufeng Li, Jian Jiang, Jingfeng Wang, Jie Fan, Minglong Chen, Baopeng Tang, Wei Li, Qiang Wu, Bei Shi, Shenghua Zhou, Xingsheng Zhao, Yuehui Yin, Zheng Zhang, Guoqiang Zhong, Xuebin Han, Fan Liu, Ming Wu, Lianjun Gao, Bo Yang, Yanhong Tang, He Huang, Congxin Huang
BACKGROUND: The latest information regarding the awareness of atrial fibrillation (AF) remains limited in China. OBJECTIVES: The present study aimed to understand the variation and disparity in awareness of AF in China. METHODS: The cross-sectional study used data from the 2020 nationwide epidemiology survey on AF among adults aged 18 years or older in mainland China to assess the prevalence of AF awareness. The awareness of AF diagnostic methods and outcomes was also assessed using an interviewer-administered questionnaire...
March 10, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38471479/prevalence-and-characteristics-of-known-versus-newly-detected-atrial-fibrillation-in-ischemic-stroke-a-population-based-study
#32
JOURNAL ARTICLE
Aurore Mitaine, Gauthier Duloquin, Thibaut Pommier, Catherine Vergely, Charles Guenancia, Yannick Béjot
BACKGROUND: Atrial fibrillation (AF) is frequently diagnosed during the acute stage of ischemic (IS), and it may reflect undiagnosed AF before stroke, thus representing a missed opportunity for stroke prevention. This population-based study aimed to assess the prevalence of known AF (KAF) and AF diagnosed early after IS (AFDAS), and to compare clinical and brain/arterial imaging characteristics between patients. METHODS: Among patients with acute IS recorded in the population-based Dijon Stroke Registry, France (2013-2020), we identified those with KAF or AFDAS...
March 12, 2024: Neuroepidemiology
https://read.qxmd.com/read/38471056/statin-therapy-for-secondary-prevention-in-ischemic-stroke-patients-with-cerebral-microbleeds
#33
JOURNAL ARTICLE
Luis Prats-Sanchez, Pol Camps-Renom, Philip S Nash, Duncan Wilson, Gareth Ambler, Jonathan G Best, Marina Guasch-Jiménez, Anna Ramos-Pachón, Alejandro Martinez-Domeño, Álvaro Lambea-Gil, Garbiñe Ezcurra Díaz, Daniel Guisado-Alonso, Houwei Du, Rustam Al-Shahi Salman, Hans Rolf Jäger, Gregory Y Lip, Hakan Ay, Simon Jung, Natan M Bornstein, Thomas Gattringer, Sebastian Eppinger, Dianne H van Dam-Nolen, Masatoshi Koga, Kazunori Toyoda, Felix Fluri, Thanh G Phan, Velandai K Srikanth, Ji Hoe Heo, Hee-Joon Bae, Peter J Kelly, Toshio Imaizumi, Julie Staals, Sebastian Köhler, Yusuke Yakushiji, Dilek Necioglu Orken, Eric E Smith, Joanna M Wardlaw, Francesca M Chappell, Stephen D Makin, Jean-Louis Mas, David Calvet, Régis Bordet, Christopher P Chen, Roland Veltkamp, Nagaendran Kandiah, Robert J Simister, Frank-Erik De Leeuw, Stefan T Engelter, Nils Peters, Yannie O Soo, Annaelle Zietz, Jeroen Hendrikse, Werner H Mess, David J Werring, Joan Marti-Fabregas
BACKGROUND AND OBJECTIVES: The association between statin use and the risk of intracranial hemorrhage (ICrH) following ischemic stroke (IS) or transient ischemic attack (TIA) in patients with cerebral microbleeds (CMBs) remains uncertain. This study investigated the risk of recurrent IS and ICrH in patients receiving statins based on the presence of CMBs. METHODS: We conducted a pooled analysis of individual patient data from the Microbleeds International Collaborative Network, comprising 32 hospital-based prospective studies fulfilling the following criteria: adult patients with IS or TIA, availability of appropriate baseline MRI for CMB quantification and distribution, registration of statin use after the index stroke, and collection of stroke event data during a follow-up period of ≥3 months...
April 9, 2024: Neurology
https://read.qxmd.com/read/38470020/half-dose-direct-oral-anticoagulation-versus-warfarin-for-atrial-fibrillation-following-cardiac-surgery
#34
JOURNAL ARTICLE
Sabet W Hashim, Susan Collazo, Amanda Greco, Jeff F Mather, Raymond G McKay
BACKGROUND: Optimal anticoagulation strategies have not been defined for patients with atrial fibrillation following cardiac surgery. METHODS: From a total cohort of 228 patients with pre-existing or new onset atrial fibrillation following coronary artery bypass grafting and/or valve surgery, we compared in-hospital and 30-day outcomes in 119 patients treated with low-dose aspirin and a half-dose direct oral anticoagulant (DOAC) versus 109 treated with low-dose aspirin and warfarin...
March 12, 2024: Journal of Cardiovascular Surgery
https://read.qxmd.com/read/38468834/how-the-hemostasis-laboratory-can-help-clinicians-to-manage-patients-on-oral-anticoagulants
#35
REVIEW
Armando Tripodi, Marigrazia Clerici, Erica Scalambrino, Pasquale Agosti, Paolo Bucciarelli, Flora Peyvandi
Oral anticoagulants are widely used to treat or prevent cardiovascular diseases in millions of patients worldwide. They are the drugs of choice for stroke prevention and systemic embolism in patients with non-valvular atrial fibrillation and prosthetic heart valves, as well as for treatment/prevention of venous thromboembolism. Oral anticoagulants include vitamin K antagonists (VKAs) and direct oral anticoagulants (DOACs). The hemostasis laboratory plays a crucial role in the management of treated patients, spanning from dose adjustment based on laboratory testing that applies to VKAs to the measurement of drug concentrations in special situations that apply to DOACs...
2024: Mediterranean Journal of Hematology and Infectious Diseases
https://read.qxmd.com/read/38468182/a-device-related-fistula-between-coronary-artery-and-left-atrial-appendage-following-left-atrial-appendage-closure-case-presentation
#36
Xiaohua Liu, Yizhou Xu
INTRODUCTION: Left atrial appendage (LAA) closure (LAAC) is considered a viable alternative to anticoagulation therapy for stroke prevention in nonvalvular atrial fibrillation, we report a case with a less common shunt resulting from a device-related coronary artery-appendage fistula (CAAF) following LAAC. METHODS AND RESULTS: A 67-year-old male with a history of LAAC was referred to our emergency room with recurrent chest pain and palpitations and was diagnosed with ischemic angina pectoris...
March 11, 2024: Journal of Cardiovascular Electrophysiology
https://read.qxmd.com/read/38467238/the-impact-of-sex-on-stroke-care-from-epidemiology-to-outcome
#37
JOURNAL ARTICLE
Kathryn Grimes, Prachi Mehndiratta, Seemant Chaturvedi
BACKGROUND: Carotid stenosis and atrial fibrillation are key risk factors for development of hemispheric strokes. In this review we aim to identify sex-specific differences in the pathophysiology and treatment of these risk factors and areas for future study. KEY FINDINGS: Women are underrepresented in research studies of stroke in patients with carotid disease and atrial fibrillation. However, key differences have been found between men and women that suggest that the development of carotid disease and atrial fibrillation occur at later stages of life and are associated with higher severity of stroke...
March 9, 2024: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://read.qxmd.com/read/38466973/optimization-of-using-multiple-machine-learning-approaches-in-atrial-fibrillation-detection-based-on-a-large-scale-data-set-of-12-lead-electrocardiograms-cross-sectional-study
#38
JOURNAL ARTICLE
Beau Bo-Sheng Chuang, Albert C Yang
BACKGROUND: Atrial fibrillation (AF) represents a hazardous cardiac arrhythmia that significantly elevates the risk of stroke and heart failure. Despite its severity, its diagnosis largely relies on the proficiency of health care professionals. At present, the real-time identification of paroxysmal AF is hindered by the lack of automated techniques. Consequently, a highly effective machine learning algorithm specifically designed for AF detection could offer substantial clinical benefits...
March 11, 2024: JMIR Formative Research
https://read.qxmd.com/read/38465648/cardiovascular-management-of-patients-undergoing-hematopoietic-stem-cell-transplantation-from-pretransplantation-to-survivorship-a-scientific-statement-from-the-american-heart-association
#39
REVIEW
Salim S Hayek, Vlad G Zaha, Carmel Bogle, Anita Deswal, Amelia Langston, Seth Rotz, Alexi Vasbinder, Eric Yang, Tochukwu Okwuosa
Hematopoietic stem cell transplantation can cure various disorders but poses cardiovascular risks, especially for elderly patients and those with cardiovascular diseases. Cardiovascular evaluations are crucial in pretransplantation assessments, but guidelines are lacking. This American Heart Association scientific statement summarizes the data on transplantation-related complications and provides guidance for the cardiovascular management throughout transplantation. Hematopoietic stem cell transplantation consists of 4 phases: pretransplantation workup, conditioning therapy and infusion, immediate posttransplantation period, and long-term survivorship...
March 11, 2024: Circulation
https://read.qxmd.com/read/38465605/cardiovascular-management-in-asymptomatic-silent-cerebral-microbleeds-and-suspected-cerebral-amyloid-angiopathy
#40
REVIEW
Andreas Charidimou, Eric E Smith
Cerebral microbleeds (CMBs) detected on blood-sensitive magnetic resonance imaging sequences are usually a sign of an underlying cerebral small vessel disease such as sporadic cerebral amyloid angiopathy or sporadic nonamyloid small vessel pathology (eg, arteriolosclerosis). Much of the enduring interest in CMBs relates to their high prevalence (partly due to the widespread use of magnetic resonance imaging) in the context of stroke, cognitive impairment and in healthy individuals, and the clinical uncertainties created about the safety of antithrombotic medications due to their association with both future hemorrhagic and ischemic stroke...
March 11, 2024: Stroke; a Journal of Cerebral Circulation
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