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https://www.readbyqxmd.com/read/29653080/surgical-treatment-of-native-and-prosthetic-aortic-infection-with-xenopericardial-tube-grafts
#1
Maximilian Kreibich, Matthias Siepe, Julia Morlock, Friedhelm Beyersdorf, Stoyan Kondov, Johannes Scheumann, Fabian A Kari, Tim Berger, Holger Schröfel, Bartosz Rylski, Martin Czerny
BACKGROUND: To report our results of surgical treatment of native and prosthetic aortic infection with xenopericardial tube-grafts from the ascending aorta to beyond the bifurcation. METHODS: Within a 28-month period, 20 patients were treated with a bovine self-made pericardial tube graft to replace infected vascular grafts (after conventional surgical aortic replacement or endovascular stentgraft implantation) or to treat a contaminated surgical site. An integrated standardized therapeutic concept was applied in all patients consisting of complete removal of the infected prosthetic material, extensive debridement, and orthotopic vascular reconstruction with self-made tube grafts constructed from a bovine pericardial patch...
April 10, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29651329/ischaemia-of-the-medullary-cone-after-stent-graft-implantation-in-a-patient-with-abdominal-aortic-aneurysm-a-case-study
#2
Mariusz Wachowski, Michał Polguj, Janusz Ścibór, Agata Majos
Preoperative visualization of the Adamkiewicz artery - the vessel which is to a great extent responsible for supplying blood to the medullary cone - is an important step which must be taken before initiating restorative procedures in the aorta. We present a case of a 67-year-old patient who underwent an intravascular stent-graft implantation procedure, due to clinical signs of abdominal aortic aneurysm. Routine pre-operative computed tomography examination failed to demonstrate the Adamkiewicz artery. On the second day after the surgery, as a result of unexpected clinical deterioration, an magnetic resonance imaging examination of the lumbar spine was carried out...
March 2018: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/29649954/anatomical-considerations-and-open-surgery-to-treat-juxtarenal-abdominal-aortic-aneurysms
#3
Georgiana Samoila, Ian Michael Williams
INTRODUCTION: Historically, the open approach to the abdominal aorta has been transperitoneal (TP). In comparison, a retroperitoneal (RP) incision exposes the lateral wall of the suprarenal aorta for clamp application and midline structures such as the duodenum and pancreas are not encountered. Proximal clamp position for open repair of juxtarenal abdominal aortic aneurysm (JR-AAA) is suprarenal, supra-superior mesenteric, or supraceliac. While RP and TP approaches have previously been compared for physiological reasons, there are currently no randomized controlled trials comparing these methods from an anatomical perspective...
January 1, 2018: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29643879/transesophageal-echocardiography-in-cardiogenic-embolic-cerebral-infarction
#4
Wen Chu, Hua Wang
Objective: To evaluate the diagnostic values of transesophageal echocardiography (TEE) and transthoracic echocardiography (TTE) in cardiogenic embolic cerebral infarction. Methods: Fifty patients with occult cerebral infarction who were admitted to the hospital between June 2015 and June 2016 were selected as research subjects. The patients were diagnosed by transesophageal echocardiography and transthoracic echocardiography. Diagnostic data were compared to analyze the values of the two diagnostic methods...
January 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29643699/clinical-efficacy-of-transthoracic-echocardiography-for-screening-abdominal-aortic-aneurysm-in-turkish-patients
#5
Salih Kilic, Erhan Saracoglu, Yusuf Cekici
Background: The objective of this study was to investigate the prevalence of abdominal aortic aneurysm (AAA) in Turkish patients aged ≥ 65 years, and to demonstrate the applicability of echocardiography to AAA screening. Methods: Transthoracic echocardiography (TTE) was performed in all consecutive patients aged ≥ 65 years who were referred to cardiology clinics or were referred from other outpatient clinics. The abdominal aorta (AA) of each patient was scanned using the same probe, and the time spent was recorded...
March 2018: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29629554/single-stage-thoracic-aortic-replacement-and-aortic-valve-replacement-via-clamshell-thoracotomy
#6
Thomas Schachner
Aortic surgery is sometimes complicated by aortic arch anomalies. This tutorial illustrates the technique of single-stage thoracic aorta replacement and aortic valve replacement via a clamshell thoracotomy in acute aortic arch dissection with proximal aneurysms of the left subclavian artery and an aberrant right subclavian artery. The advantage of this technique is that only brief partial hypothermic circulatory arrest is required and the procedure can be performed with one quadrifurcated tube graft.
February 20, 2018: Multimedia Manual of Cardiothoracic Surgery: MMCTS
https://www.readbyqxmd.com/read/29628493/effect-of-a-high-sucrose-diet-on-abdominal-aortic-aneurysm-development-in-a-hypoperfusion-induced-animal-model
#7
Chie Miyamoto, Hirona Kugo, Keisuke Hashimoto, Ayaka Sawaragi, Nobuhiro Zaima, Tatsuya Moriyama
Abdominal aortic aneurysm (AAA) is a vascular disease that results in rupture of the abdominal aorta. The risk factors for the development of AAA include smoking, male sex, hypertension, and age. AAA has a high mortality rate, but therapy for AAA is restricted to surgery in cases of large aneurysms. Clarifying the effect of dietary food on the development of AAA would be helpful for patients with AAAs. However, the relationship between dietary habits and the development of AAA is largely unknown. In our previous study, we demonstrated that adipocytes in vascular wall can induce the rupture of AAA...
April 9, 2018: Journal of Oleo Science
https://www.readbyqxmd.com/read/29625025/ltbp3-pathogenic-variants-predispose-individuals-to-thoracic-aortic-aneurysms-and-dissections
#8
Dong-Chuan Guo, Ellen S Regalado, Amelie Pinard, Jiyuan Chen, Kwanghyuk Lee, Christina Rigelsky, Lior Zilberberg, Ellen M Hostetler, Micheala Aldred, Stephanie E Wallace, Siddharth K Prakash, Suzanne M Leal, Michael J Bamshad, Deborah A Nickerson, Marvin Natowicz, Daniel B Rifkin, Dianna M Milewicz
The major diseases affecting the thoracic aorta are aneurysms and acute dissections, and pathogenic variants in 11 genes are confirmed to lead to heritable thoracic aortic disease. However, many families in which multiple members have thoracic aortic disease do not have alterations in the known aortopathy genes. Genes highly expressed in the aorta were assessed for rare variants in exome sequencing data from such families, and compound rare heterozygous variants (p.Pro45Argfs∗ 25 and p.Glu750∗ ) in LTBP3 were identified in affected members of one family...
April 5, 2018: American Journal of Human Genetics
https://www.readbyqxmd.com/read/29624112/cathepsin-s-is-associated-with-degradation-of-collagen-i-in-abdominal-aortic-aneurysm
#9
Veronika Klaus, Fadwa Schmies, Christian Reeps, Matthias Trenner, Sarah Geisbüsch, Fabian Lohoefer, Hans-Henning Eckstein, Jaroslav Pelisek
BACKGROUND: Cathepsins have been described in the pathogenesis of abdominal aortic aneurysm (AAA), their exact role, especially in collagen degradation, is still unclear. The aim of the present study was therefore to analyse relevant cathepsins in human AAA tissue samples in relation to collagen I, III, and their degradation products. MATERIALS AND METHODS: Samples from 37 AAA patients obtained from elective open surgical repair and eight healthy non-aneurysmatic aortas from kidney donors were included...
April 6, 2018: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/29622560/role-of-adamts-a-disintegrin-and-metalloproteinase-with-thrombospondin-motifs-5-in-aortic-dilatation-and-extracellular-matrix-remodeling
#10
Marika Fava, Javier Barallobre-Barreiro, Ursula Mayr, Ruifang Lu, Athanasios Didangelos, Ferheen Baig, Marc Lynch, Norman Catibog, Abhishek Joshi, Temo Barwari, Xiaoke Yin, Marjan Jahangiri, Manuel Mayr
OBJECTIVE: Thoracic aortic aneurysm (TAA), a degenerative disease of the aortic wall, is accompanied by changes in the structure and composition of the aortic ECM (extracellular matrix). The ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family of proteases has recently been implicated in TAA formation. This study aimed to investigate the contribution of ADAMTS-5 to TAA development. APPROACH AND RESULTS: A model of aortic dilatation by AngII (angiotensin II) infusion was adopted in mice lacking the catalytic domain of ADAMTS-5 (Adamts5Δcat )...
April 5, 2018: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/29621750/enhanced-vascular-biocompatibility-and-remodeling-of-decellularized-and-secured-xenogeneic-allogeneic-matrices-in-a-porcine-model
#11
Mathieu van Steenberghe, Thomas Schubert, Caroline Bouzin, Carlo Caravaggio, Yves Guiot, Daela Xhema, Pierre Gianello
BACKGROUND/PURPOSE: Calcifications and absence of growth potential are the major drawbacks of glutaraldehyde-treated prosthesis. Decellularized and secured xeno-/allogeneic matrices were assessed in a preclinical porcine model for biocompatibility and vascular remodeling in comparison to glutaraldehyde-fixed bovine pericardium (GBP; control). METHODS: Native human (fascia lata, pericardium) and porcine tissues (peritoneum) were used and treated. In vitro, biopsies were performed before and after treatment to assess decellularization (hematoxylin and eosin/DAPI)...
April 5, 2018: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://www.readbyqxmd.com/read/29620622/cc1-emergent-endovascular-repair-of-a-ruptured-descending-thoracic-aortic-aneurysm-in-an-arresting-patient
#12
Warren Naselsky, Charles F Evans, Brody Wehman, Bradley S Taylor
OBJECTIVE: Our goal was to present a case of emergent endovascular repair of a ruptured descending aortic aneurysm in an actively arresting patient. PATIENT: The patient was a 75-year-old woman with a known history of a 6.5-cm descending thoracic aortic aneurysm with acute onset of back pain and syncope. A computed tomographic angiogram revealed disruption of the descending thoracic aorta and a mediastinal hematoma. The patient was taken emergently to the operating room...
April 4, 2018: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29618036/quantification-of-aortic-stiffness-and-wall-stress-in-healthy-volunteers-and-abdominal-aortic-aneurysm-patients-using-time-resolved-3d-ultrasound-a-comparison-study
#13
Emiel M J van Disseldorp, Niels J Petterson, Frans N van de Vosse, Marc R H M van Sambeek, Richard G P Lopata
Aims: Using non-invasive 3D ultrasound, peak wall stress (PWS) and aortic stiffness can be evaluated, which may provide additional criteria in abdominal aortic aneurysm (AAA) risk assessment. In this study, these measures were determined in both young and age-matched individuals, and AAA patients while its relation to age, maximum diameter, and growth was assessed statistically. Methods and results: Time-resolved 3D-US data were acquired for 30 volunteers and 65 AAA patients...
March 29, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29617977/aortic-sarcoidosis-complicated-by-a-pulmonary-artery-aneurysm
#14
Wataru Uchida, Yoshiyuki Tokuda, Masato Mutsuga, Akihiko Usui
A 76-year-old woman, who had a history of ocular sarcoidosis, was incidentally found to have a huge pulmonary artery aneurysm, along with aortic, mitral and tricuspid valve insufficiency. She underwent pulmonary artery plication along with surgeries for 3 valves. A specimen of the slightly enlarged ascending aorta revealed the involvement of sarcoidosis in the aortic wall. The systemic granulomatous inflammation process of sarcoidosis possibly affected the valvular and vascular pathology. Herein, we report a rare case of aortic sarcoidosis complicated by a pulmonary artery aneurysm...
March 29, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29615357/use-of-extracorporeal-bypass-is-associated-with-improved-outcomes-in-open-thoracic-and-thoracoabdominal-aortic-aneurysm-repair
#15
Jahan Mohebali, Stephanie Carvalho, R Todd Lancaster, Emel A Ergul, Mark F Conrad, W Darrin Clouse, Richard P Cambria, Virendra I Patel
OBJECTIVE: There is no consensus on the use or benefit of extracorporeal circulation (EC) during aneurysm repair of the descending thoracic aorta (DTA) or thoracoabdominal aorta (TAA). We evaluated the role of EC during DTA or TAA aneurysm repair using U.S. Medicare data. METHODS: Medicare (2004-2007) patients undergoing open repair of nonruptured DTA or TAA aneurysm were identified by International Classification of Diseases, Ninth Revision code. Specific exclusions included ascending aortic or arch repairs, concomitant cardiac procedures, and procedures employing deep hypothermic circulatory arrest...
March 31, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29611032/thoracoabdominal-aortic-replacement-in-patients-aged-50-and-younger
#16
REVIEW
Kenji Minatoya, Yosuke Inoue, Yoshimasa Seike, Atsushi Omura, Kyokun Uehara, Hiroaki Sasaki, Hitoshi Matsuda, Junjiro Kobayashi
OBJECTIVE: Open repair of a thoracoabdominal aortic aneurysm (TAAA) has been regarded as one of the most invasive procedures in cardiovascular surgery. Conversely, endovascular technology currently enables the repair of the thoracoabdominal aorta, and this approach is less invasive. However, the long-term durability of this method of endovascular repair remains unknown. This investigation retrospectively analyzed the long-term durability of thoracoabdominal aorta repair in patients aged 50 and younger...
April 2, 2018: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29603401/platelet-to-lymphocyte-ratio-in-acute-aortic-dissection
#17
Eftihia Sbarouni, Panagiota Georgiadou, Elias Kosmas, Antonis Analitis, Vassilis Voudris
BACKGROUND: Inflammation plays an important role in the initiation and progression of acute aortic dissection (AAD). New inflammatory indices derived from full cell blood count and its differential may be associated with increased risk. We evaluated platelet-lymphocyte (PLR), red cell distribution width (RDW) and RDW/PLT's (platelets) (RPR) in AAD. METHODS: We studied 120 consecutive patients with AAD type I admitted for emergency surgery (group I), 121 consecutive patients with aortic aneurysms of the ascending aorta prior to elective repair (group II) and 121 controls (group III), age and sex matched...
March 30, 2018: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29600943/silent-arterial-inflammation-during-the-apparent-remission-state-of-takayasu-s-arteritis-what-do-cytokines-tell-us
#18
Bruna Savioli, Bruno Ramos Salu, Marlon Vilela de Brito, Maria Luiza Vilela Oliva, Alexandre W S de Souza
OBJECTIVES: To evaluate serum cytokines as biomarkers of smoldering disease activity in patients with Takayasu's arteritis (TAK) in remission. METHODS: Thirty-four TAK patients with stable disease during the last 6 months and 22 healthy controls (HC) were included in a cross-sectional study. Serum levels of pro-inflammatory, anti-inflammatory, Th1, Th2, Th9, Th17 and Th22 cytokines were measured by the multiplex technique. RESULTS: No significant differences regarding serum cytokine levels were found between TAK patients and HC...
March 19, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29600098/interrupted-right-sided-aortic-arch-performance-of-umbilical-xenograft-after-primary-neonatal-corrective-surgery
#19
Jasmin H Shahinian, Daniel Tobler, Thomas Wolff, Martin Grapow
Interrupted aortic arch (IAA) associated with right-sided aorta descendens is a rare congenital malformation. We present a case of a female patient who was diagnosed with type B IAA and received primary corrective surgery as a neonate. A bovine umbilical vascular graft was used to establish aortic arch continuity. Thirty-nine years later the same patient presents with graft-dilatation and a distal aneurysm requiring a surgery. This case shows a late complication of a biological xenograft in term of long-term material performance...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29594688/coupled-morphological-hemodynamic-computational-analysis-of-type-b-aortic-dissection-a-longitudinal-study
#20
Huijuan Xu, Marina Piccinelli, Bradley G Leshnower, Adrien Lefieux, W Robert Taylor, Alessandro Veneziani
Progressive false lumen aneurysmal degeneration in type B aortic dissection (TBAD) is a complex process with a multi-factorial etiology. Patient-specific computational fluid dynamics (CFD) simulations provide spatial and temporal hemodynamic quantities that facilitate understanding this disease progression. A longitudinal study was performed for a TBAD patient, who was diagnosed with the uncomplicated TBAD in 2006 and treated with optimal medical therapy but received surgery in 2010 due to late complication...
March 28, 2018: Annals of Biomedical Engineering
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