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Aorta aneurysm

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https://www.readbyqxmd.com/read/29022854/single-center-mid-term-experience-with-chimney-graft-technique-for-the-preservation-of-flow-to-the-supra-aortic-branches
#1
Robert Shahverdyan, Spyridon Mylonas, Michael Gawenda, Jan Brunkwall
Objectives To investigate the feasibility and the mid-term outcomes of the chimney-graft technique for the revascularization of supra-aortic branches in patients with thoracic aortic pathologies involving the aortic arch. Methods A retrospective analysis of a prospectively maintained database between January 2010 and July 2016 was performed. Primary endpoints were 30-day and overall mortality. Secondary endpoints were technical success, target vessel patency, stroke/transitory ischemic attack and type I/III endoleak rate...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/29019146/spinal-cord-injury-after-thoracic-endovascular-aortic-aneurysm-repair
#2
Hamdy Awad, Mohamed Ehab Ramadan, Hosam F El Sayed, Daniel A Tolpin, Esmerina Tili, Charles D Collard
PURPOSE: Thoracic endovascular aortic aneurysm repair (TEVAR) has become a mainstay of therapy for aneurysms and other disorders of the thoracic aorta. The purpose of this narrative review article is to summarize the current literature on the risk factors for and pathophysiology of spinal cord injury (SCI) following TEVAR, and to discuss various intraoperative monitoring and treatment strategies. SOURCE: The articles considered in this review were identified through PubMed using the following search terms: thoracic aortic aneurysm, TEVAR, paralysis+TEVAR, risk factors+TEVAR, spinal cord ischemia+TEVAR, neuromonitoring+thoracic aortic aneurysm, spinal drain, cerebrospinal fluid drainage, treatment of spinal cord ischemia...
October 10, 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/28994804/biodegradable-magnesium-stent-treatment-of-saccular-aneurysms-in-a-rat-model-introduction-of-the-surgical-technique
#3
Edin Nevzati, Jeannine Rey, Daniel Coluccia, Donato D'Alonzo, Basil Grüter, Luca Remonda, Javier Fandino, Serge Marbacher
The steady progess in the armamentarium of techniques available for endovascular treatment of intracranial aneurysms requires affordable and reproducable experimental animal models to test novel embolization materials such as stents and flow diverters. The aim of the present project was to design a safe, fast, and standardized surgical technique for stent assisted embolization of saccular aneurysms in a rat animal model. Saccular aneurysms were created from an arterial graft from the descending aorta.The aneurysms were microsurgically transplanted through end-to-side anastomosis to the infrarenal abdominal aorta of a syngenic male Wistar rat weighing >500 g...
October 1, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28987784/peritoneal-pre-conditioning-reduces-macrophage-marker-expression-in-collagen-containing-engineered-vascular-grafts
#4
Mozhgan Shojaee, Kristin B Wood, Lisa K Moore, Chris A Bashur
Engineered vascular grafts have shown promise as arteriovenous shunts, but they have not yet progressed to clinical trials for coronary arteries <4 mm in diameter such as the coronary arteries. Control over initial biomaterial properties and remodeling are necessary to generate viable grafts. In this study, we blended collagen with a synthetic material, poly(ε-caprolactone), to modulate the post-grafting inflammatory response while avoiding aneurysmal-like dilation and failure that can occur with pure collagen grafts...
October 5, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28983674/contrast-enhanced-ultrasound-ceus-of-the-abdominal-vasculature
#5
REVIEW
Vasileios Rafailidis, Cheng Fang, Gibran T Yusuf, Dean Y Huang, Paul S Sidhu
Vascular diseases account for a significant proportion of abdominal pathology and represent a common referral source for abdominal ultrasonographic examinations. B-mode, color Doppler, and spectral Doppler analyses are well-established in the evaluation of abdominal blood vessels although they may occasionally be limited by lower sensitivity for slow flow visualization or the deeper location of abdominal vascular structures. The introduction of microbubbles as ultrasonographic contrast agents has rendered contrast-enhanced ultrasound (CEUS), a valuable complementary ultrasonographic technique, which is capable of addressing clinically significant problems and guiding patient management...
October 5, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28983176/bentall-operation-in-a-patient-with-an-anomalous-left-circumflex-artery-case-report-and-review
#6
Ivo Gasparovic, Panagiotis Artemiou, Mikulas Kiss, Michal Hulman
Anomalous origin of a left circumflex artery from the right coronary sinus represents a technical challenge in patients who require aortic valve/root procedures. This case report describes a patient who presented with bicuspid aortic valve, anomalous origin of the circumflex artery, severe aortic regurgitation, and aneurysm of the ascending aorta as well as aortic root that was safely managed following the Bentall procedure with the combined button technique.
October 2017: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/28982723/increased-galectin-3-levels-are-associated-with-abdominal-aortic-aneurysm-progression-and-inhibition-of-galectin-3-decrease-elastase-induced-aaa-development
#7
Carlos-Ernesto Fernandez-García, Carlos Tarin, Raquel Roldan-Montero, Diego Martinez-Lopez, Monica Torres-Fonseca, Jes S Lindhot, Melina Vega de Ceniga, Jesús Egido, Natalia Lopez de Andres, Luis-Miguel Blanco-Colio, Jose-Luis Martín-Ventura
Abdominal aortic aneurysm (AAA) evolution is unpredictable. Moreover, no specific treatment exists for AAA, except surgery to prevent aortic rupture. Galectin-3 has been previously associated with CVD, but its potential role in AAA have not been addressed. Galectin-3 levels were increased in plasma of AAA patients (n=225) compared to controls (n=100). Moreover, galectin-3 concentrations were associated with need for surgical repair, independently of potential confounding factors. Galectin-3 mRNA and protein expression were increased in human AAA samples compared to healthy aortas...
October 5, 2017: Clinical Science (1979-)
https://www.readbyqxmd.com/read/28978900/subarachnoid-aneurysmal-hemorrhage-associated-with-coarctation-of-the-aorta-case-report-and-review-of-the-literature
#8
Ryuta Nakae, Yu Fujiki, Shoji Yokobori, Yasutaka Naoe, Hiroyuki Yokota
Intracranial aneurysms (IAs) that undergo rupture causing subarachnoid hemorrhage (SAH), are common in young patients with coarctation of the aorta (CoA), but rarer in middle-aged and elderly patients. The pathogenesis of IAs associated with CoA remains unclear. We report the case of a 50-year-old woman who presented with SAH. On evaluation, six IAs were distributed among the anterior communicating artery (ACoA) (ruptured), distal segments of both anterior cerebral arteries (ACA), the left internal carotid artery (ICA), the bifurcation of the left middle cerebral artery (MCA)/MCA early branch, and the inferior trunk of the left MCA...
2017: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
https://www.readbyqxmd.com/read/28978552/tryptophan-derived-3-hydroxyanthranilic-acid-contributes-to-angiotensin-ii-induced-abdominal-aortic-aneurysm-formation-in-mice-in-vivo
#9
Qiongxin Wang, Ye Ding, Ping Song, Huaiping Zhu, Imoh S Okon, Nan-Yang Ding, Houzao Chen, Depei Liu, Ming-Hui Zou
Background -Abnormal amino acid metabolism is associated with vascular disease. However, the causative link between dysregulated tryptophan metabolism and abdominal aortic aneurysm (AAA) is unknown. Methods -Indoleamine 2,3-dioxygenase (IDO) is the first and rate-limiting enzyme in the kynurenine pathway of tryptophan metabolism. Mice with deficiencies in both apolipoprotein e (Apoe) and IDO (Apoe(-/-)/IDO(-/-)) were generated by cross-breeding IDO(-/-) mice with Apoe(-/-) mice. Results -The acute infusion of angiotensin II (AngII) markedly increased the incidence of AAA in Apoe(-/-) mice, but not in Apoe(-/-)/IDO(-/-) mice, which presented decreased elastic lamina degradation and aortic expansion...
October 4, 2017: Circulation
https://www.readbyqxmd.com/read/28977406/modified-reverse-aortoplasty-versus-extended-anastomosis-in-patients-with-coarctation-of-the-aorta-and-distal-arch-hypoplasia
#10
Ilya Soynov, Yuriy Sinelnikov, Yuriy Gorbatykh, Alexander Omelchenko, Igor Kornilov, Nataliya Nichay, Alexander Bogachev-Prokophiev, Alexander Karaskov
OBJECTIVES: The aim of our prospective randomized study was to compare modified reverse aortoplasty (MRA) and extended end-to-end anastomosis (EEA). METHODS: We have assessed the operative correction results in 54 infants with coarctation of the aorta and distal aortic arch hypoplasia who underwent primary repair in our institute between July 2013 and February 2014. All of the patients were <12 months old when they had the operation. Patients were randomly assigned to 2 arms: modified reverse subclavian flap angioplasty (MRA group; n  = 27) or extended end-to-end anastomosis (EEA group; n  = 27)...
July 25, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28977379/single-centre-experience-with-the-frozen-elephant-trunk-technique-in-251-patients-over-15%C3%A2-years
#11
Malakh Shrestha, Andreas Martens, Tim Kaufeld, Erik Beckmann, Sebastian Bertele, Heike Krueger, Julia Neuser, Felix Fleissner, Fabio Ius, Firas Abd Alhadi, Jasmin Hanke, Jan D Schmitto, Serghei Cebotari, Matthias Karck, Axel Haverich, Ajay Chavan
OBJECTIVES: Our goal was to present our 15-year experience (2001-2015) with the frozen elephant trunk (FET) technique. METHODS: A total of 251 patients (82 with aortic aneurysms, 96 with acute aortic dissection type A, 4 with acute type B dissections, 52 with chronic aortic dissection type A, 17 with chronic type B dissection and 67 redo cases) underwent FET implantation with either the custom-made Chavan-Haverich ( n  = 66), the Jotec E-vita ( n  = 31) or the Vascutek Thoraflex hybrid ( n  = 154) prosthesis...
August 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28977104/association-between-renal-cysts-and-abdominal-aortic-aneurysm-a-case-control-study
#12
Hélio Miguel de Azevêdo Bião Veiga, Leandro José Correia da Silva, Carlos Henrique Suzuki Bellucci, Marcus Vinicius Miranda Dos Santos, Ricardo Brianezi Tiraboschi, Victor Pereira Paschoalin, Lucas Borba, Cristiano Mendes Gomes, José Murillo Bastos-Netto, José de Bessa
OBJECTIVE: To investigate the positive association between the presence of simple renal cysts (SRCs) and abdominal aortic aneurysm (AAA). METHOD: In a retrospective case-control study including subjects aged > 50 years, we evaluated the incidence of SRCs on computed tomography (CT) scan. We compared 91 consecutive patients with AAA referred from the Division of Vascular Surgery and 396 patients without AAA, randomly selected after being matched by age and gender from 3,186 consecutive patients who underwent abdominal CT...
August 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28976392/-approach-to-aortic-aneurysms-in-the-elderly
#13
Şeyda Günay, N Sümeyye Güllülü
There is an increase in the number of older persons worldwide. Because of this in the future we will much more manage the diseases which are more commonly seen in elderly in daily practice. One of the mortal diseases commonly seen in elderly patients is aortic aneurysm. Aort aneurysms are vary rare in patients under 50 age. When a patient over 65 age is examined, aortic aneurysm should take place in differential diagnosis list. aneurysm may be seen at both thoracic and abdominal aorta, but abdominal aorta is a more common site...
September 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28973148/a-constitutive-bcl2-down-regulation-aggravates-the-phenotype-of-pkd1-mutant-induced-polycystic-kidney-disease
#14
Laurence Duplomb, Nathalie Droin, Olivier Bouchot, Christel Robinet Thauvin, Ange-Line Bruel, Julien Thevenon, Patrick Callier, Guillaume Meurice, Noémie Pata-Merci, Romaric Loffroy, David Vandroux, Romain Da Costa, Virginie Carmignac, Eric Solary, Laurence Faivre
The main identified function of BCL2 protein is to prevent cell death by apoptosis. Mice knock-out for Bcl2 demonstrate growth retardation, severe polycystic kidney disease (PKD), gray hair and lymphopenia, and die prematurely after birth. Here, we report a 40-year-old male referred to for abdominal and thoracic aortic dissection with associated aortic root aneurysm, PKD, lymphocytopenia with a history of T cell lymphoblastic lymphoma, white hair since the age of 20, and learning difficulties. PKD, which was also detected in the father and sister, was related to an inherited PKD1 mutation...
September 11, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28973104/use-of-resuscitative-endovascular-balloon-occlusion-of-the-aorta-for-proximal-aortic-control-in-patients-with-severe-hemorrhage-and-arrest
#15
Megan Brenner, William Teeter, Melanie Hoehn, Jason Pasley, Peter Hu, Shiming Yang, Anna Romagnoli, Jose Diaz, Deborah Stein, Thomas Scalea
Importance: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a percutaneous transfemoral balloon technique used in select centers for resuscitation and temporary hemostasis, often instead of emergency department thoracotomy. The ability to perform aortic occlusion (AO) with an intravascular device allows focused occlusion at the most distal level to perfuse proximal regions while slowing hemorrhage to injured areas. Objective: To describe what is to date the largest single-institution experience with REBOA in the United States...
September 27, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28958475/successful-use-of-resuscitative-endovascular-balloon-occlusion-of-the-aorta-in-the-treatment-of-ruptured-8-5-cm-splenic-artery-aneurysm
#16
Gabriel Ologun, Keith Sharpton, Paul Granet
Spontaneous rupture of splenic artery aneurysm is a rare cause of acute abdomen with hemorrhagic shock that is a life-threatening surgical emergency. We report a case of a spontaneous rupture of an 8.5-cm splenic artery aneurysm managed using resuscitative endovascular balloon occlusion of the aorta (ER-REBOA Catheter; Prytime Medical Inc, Boerne, Tex) for proximal control of the aorta before laparotomy. This is a minimally invasive technique that can be used as an adjunct to massive transfusion resuscitation and laparotomy for life-threatening intraperitoneal hemorrhage...
September 25, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28958041/endovascular-treatment-of-non-dissected-ascending-aorta-disease-a-systematic-review
#17
Changtian Wang, Evelyn Regar, Mario Lachat, Ludwig K von Segesser, Francesco Maisano, Enrico Ferrari
Severe ascending aorta disease includes aneurysms, pseudoaneurysms (ascending aorta pseudoaneurysms), penetrating aortic ulcers and Type A aortic dissections. Surgical replacement of the aortic root, ascending aorta or aortic arch is the common treatment for severe ascending aortic disease involving the root, the ascending aorta and/or the arch. Despite good surgical results, there is still a risk for morbidity and mortality following surgery for ascending aorta replacement when elderly patients or patients at high risk for surgery are concerned...
September 18, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28956257/renal-protection-in-thoracoabdominal-aortic-aneurysm-surgery
#18
Mohamad Bashir, Amer Harky, Benjamin Adams, Kit Wong, Carmelo Di Salvo, Aung Oo
It is indisputable that open thoracoabdominal aortic aneurysm (TAAA) repair remains a highly complex and sophisticated surgical intervention. Despite advancements in the imaging modality, evolution of our understanding of the pathology afflicting the aorta, intraoperative brain and spinal cord monitoring, intraoperative organ protection, postoperative critical care and organ support, monitoring and the close follow-up of affected patients, this type of surgery remains a challenge to the surgeon and the patient...
September 27, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28955701/sequential-hybrid-repair-of-aorta-and-bilateral-common-iliac-arteries-secondary-to-chronic-aortic-dissection-with-extensive-aneurysmal-degeneration-in-a-marfan-patient
#19
Carlos A Hinojosa, Javier E Anaya-Ayala, Hugo Laparra-Escareno, Rene Lizola, Adriana Torres-Machorro
Marfan syndrome is a connective tissue disorder associated with aortic dissection, aneurysmal degeneration and rupture. These cardiovascular complications represent the main cause of mortality, therefore repair is indicated. We present a 35-year-old woman who experienced acute onset of chest pain. Her imaging revealed a chronic DeBakey type I dissection with aortic root dilation and descending thoracic aneurysmal degeneration. She underwent a Bentall procedure and endovascular exclusion of the descending thoracic aortic aneurysm...
September 2017: Vascular Specialist International
https://www.readbyqxmd.com/read/28955084/de-novo-descending-aorta-thrombus-in-a-patient-with-metastatic-colorectal-cancer-a-case-report
#20
Om Parkash, Adil Ayub, Buria Naeem, Saeed Hamid
Thromboembolic events in patients with cancer are frequently reported in literature and usually involve the venous circulation. De novo thrombus formation in the arterial system without any underlying atherosclerosis, dissection or aneurysm is extremely rare. We report the case of a patient with metastatic colorectal carcinoma who developed a thrombus in the descending aorta without any intervention or risk factors. The patient presented with non-specific gastrointestinal symptoms. A CT scan revealed an aortic thrombus obstructing 70% of the lumen...
October 2017: JPMA. the Journal of the Pakistan Medical Association
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