keyword
MENU ▼
Read by QxMD icon Read
search

D68

keyword
https://www.readbyqxmd.com/read/28071799/seroepidemiological-and-phylogenetic-characterisation-of-neurotropic-enteroviruses-in-ireland-2005-2014
#1
Jorge Abboud Guerra, Allison Waters, Alison Kelly, Ursula Morley, Paul O'Reilly, Edwin O'Kelly, Jonathan Dean, Robert Cunney, Piaras O'Lorcain, Suzanne Cotter, Jeff Connell, Joanne O'Gorman, William W Hall, Michael Carr, Cillian F De Gascun
Enteroviruses (EVs) are associated with a broad spectrum of clinical presentation, including aseptic meningitis (AM), encephalitis, hand, foot and mouth disease, acute flaccid paralysis and acute flaccid myelitis. Epidemics occur sporadically and are associated with increased cases of AM in children. The present study describes the seroepidemiological analysis of circulating EVs in Ireland from 2005-2014 and phylogenetic characterisation of echovirus 30 (E-30), enterovirus A71 (EV-A71) and enterovirus D68 (EV-D68)...
January 10, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28028115/epidemiologic-analysis-of-respiratory-viral-infections-mainly-in-hospitalized-children-and-adults-in-a-midwest-university-medical-center-after-the-implementation-of-a-14-virus-multiplex-nucleic-acid-amplification-test
#2
Sophie Arbefeville, Patricia Ferrieri
OBJECTIVES: To investigate the etiology of viral respiratory tract infections mainly in hospitalized children and adults over a 12-month consecutive period after implementation of a 14-virus multiplex nucleic acid amplification test. METHODS: From January 2014 to January 2015, a total of 2,237 respiratory samples were analyzed with the US Food and Drug Administration-cleared eSensor Respiratory Viral Panel (GenMark Diagnostics, Carlsbad, CA). RESULTS: Of the 2,237 specimens tested, 788 specimens were positive for at least one virus, giving a positivity rate of 35...
December 27, 2016: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/27979945/complete-genome-sequences-of-nine-enterovirus-d68-strains-from-patients-of-the-lower-hudson-valley-new-york-2016
#3
Weihua Huang, Changhong Yin, Jian Zhuge, Taliya Farooq, Esther C Yoon, Sheila M Nolan, Donald Chen, John T Fallon, Guiqing Wang
Complete genome sequences of nine enterovirus D68 (EV-D68) strains from patients in New York were obtained in 2016 by metagenomic next-generation sequencing. Comparative genomic analysis suggests that a new subclade B3, with ~4.5% nucleotide divergence from subclade B1 strains causing the 2014 outbreak, is circulating in the United States in 2016.
December 15, 2016: Genome Announcements
https://www.readbyqxmd.com/read/27932649/detection-and-genomic-characterization-of-enterovirus-d68-in-respiratory-samples-isolated-in-the-united-states-in-2016
#4
Terry Fei Fan Ng, Anna Montmayeur, Christina Castro, Marshall Cone, Joey Stringer, Daryl M Lamson, Shannon L Rogers, Shur-Wern Wang Chern, Laura Magaña, Rachel Marine, Heather Rubino, Daniel Serinaldi, Kirsten St George, W Allan Nix
The genomic sequences of three 2016 enterovirus D68 (EV-D68) strains were obtained from respiratory samples of patients from Florida, Texas, and New York. These EV-D68 sequences share highest nucleotide identities with strains that circulated in North America, Europe, and Asia in 2014-2015.
December 8, 2016: Genome Announcements
https://www.readbyqxmd.com/read/27930928/human-enterovirus-d68-in-clinical-and-sewage-samples-in-israel
#5
Merav Weil, Michal Mandelboim, Ella Mendelson, Yossi Manor, Lester Shulman, Daniela Ram, Galia Barkai, Yonat Shemer, Dana Wolf, Zipi Kra-Oz, Leah Weiss, Rakefet Pando, Musa Hindiyeh, Danit Sofer
BACKGROUND: Since mid-August 2014, North America experienced a wide outbreak of Enterovirus D68 (EV-D68) associated with severe respiratory illness in children. Several other countries also reported cases of EV-D68 in 2014. OBJECTIVES: The aim of this study was to determine whether EV-D68 circulated in Israel in 2014, caused severe respiratory illness in children and was the causative agent of Acute Flaccid Paralysis. STUDY DESIGN: Archived clinical respiratory samples from a cohort of 710 hospitalized pediatric patient's (<10years old) with respiratory illness were screened for clade B specific EV-D68 by real-time PCR...
January 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/27923705/icam-5-telencephalin-is-a-functional-entry-receptor-for-enterovirus-d68
#6
Wei Wei, Haoran Guo, Junliang Chang, Yingzi Yu, Guanchen Liu, Nannan Zhang, Stephen H Willard, Shu Zheng, Xiao-Fang Yu
Enterovirus D68 (EV-D68) is a member of the Picornaviridae family. Although EV-D68-associated infection was once considered rare, it has been increasing in recent years. EV-D68 infection is most frequently associated with respiratory illness. However, it has also been implicated in a polio-like neurological disorder, acute flaccid myelitis. Although sialic acid has been implicated in EV-D68 entry, the existence of a protein receptor has yet to be clarified. Here we identify neuron-specific intercellular adhesion molecule 5 (ICAM-5/telencephalin) as a cellular receptor for sialic acid-dependent and -independent EV-D68 viruses...
November 9, 2016: Cell Host & Microbe
https://www.readbyqxmd.com/read/27918268/severe-paediatric-conditions-linked-with-ev-a71-and-ev-d68-france-may-to-october-2016
#7
Denise Antona, Manoëlle Kossorotoff, Isabelle Schuffenecker, Audrey Mirand, Marianne Leruez-Ville, Clément Bassi, Mélodie Aubart, Florence Moulin, Daniel Lévy-Bruhl, Cécile Henquell, Bruno Lina, Isabelle Desguerre
We report 59 cases of severe paediatric conditions linked with enterovirus (EV)-A71 and EV-D68 in France between May and October 2016. Fifty-two children had severe neurological symptoms. EV sequence-based typing for 42 cases revealed EV-A71 in 21 (18 subgenotype C1, detected for the first time in France) and EV-D68 in eight. Clinicians should be encouraged to obtain stool and respiratory specimens from patients presenting with severe neurological disorders for EV detection and characterisation.
November 17, 2016: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/27918255/outbreak-of-enterovirus-d68-of-the-new-b3-lineage-in-stockholm-sweden-august-to-september-2016
#8
Robert Dyrdak, Malin Grabbe, Berit Hammas, Jonas Ekwall, Karin E Hansson, Joachim Luthander, Pontus Naucler, Henrik Reinius, Maria Rotzén-Östlund, Jan Albert
We report an enterovirus D68 (EV-D68) outbreak in Stockholm Sweden in 2016. Between 22 August and 25 September EV-D68 was detected in 74/495 respiratory samples analysed at the Karolinska University Hospital. During the peak week, 30/91 (33%) samples were EV-D68 positive. Viral protein (VP)P4/VP2 sequencing revealed that cases were caused by B3 lineage strains. Forty-four (59%) EV-D68-positive patients were children aged ≤ 5 years. Ten patients had severe respiratory or neurological symptoms and one died...
November 17, 2016: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/27875593/enterovirus-d68-in-hospitalized-children-sequence-variation-viral-loads-and-clinical-outcomes
#9
Katherine Moyer, Huanyu Wang, Douglas Salamon, Amy Leber, Asuncion Mejias
BACKGROUND: An outbreak of enterovirus D68 (EV-D68) caused severe respiratory illness in 2014. The disease spectrum of EV-D68 infections in children with underlying medical conditions other than asthma, the role of EV-D68 loads on clinical illness, and the variation of EV-D68 strains within the same institution over time have not been described. We sought to define the association between EV-D68 loads and sequence variation, and the clinical characteristic in hospitalized children at our institution from 2011 to 2014...
2016: PloS One
https://www.readbyqxmd.com/read/27814404/enterovirus-d-68-infection-prophylaxis-and-vaccination-in-a-novel-permissive-animal-model-the-cotton-rat-sigmodon-hispidus
#10
Mira C Patel, Wei Wang, Lioubov M Pletneva, Seesandra V Rajagopala, Yi Tan, Tina V Hartert, Marina S Boukhvalova, Stefanie N Vogel, Suman R Das, Jorge C G Blanco
In recent years, there has been a significant increase in detection of Enterovirus D-68 (EV-D68) among patients with severe respiratory infections worldwide. EV-D68 is now recognized as a re-emerging pathogen; however, due to lack of a permissive animal model for EV-D68, a comprehensive understanding of the pathogenesis and immune response against EV-D68 has been hampered. Recently, it was shown that EV-D68 has a strong affinity for α2,6-linked sialic acids (SAs) and we have shown previously that α2,6-linked SAs are abundantly present in the respiratory tract of cotton rats (Sigmodon hispidus)...
2016: PloS One
https://www.readbyqxmd.com/read/27814328/enterovirus-d68-reemerges-globally-as-a-severe-pathogen-targeting-children
#11
Adrienne G Randolph
No abstract text is available yet for this article.
November 2016: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/27806749/the-genomic-characterization-of-enterovirus-d68-from-2011-to-2015-in-beijing-china
#12
Tie Gang Zhang, Hong Quan Li, Ai Hua Li, Meng Chen, Cheng Gong, Ming Luo, Mei Dong, Fang Huang
A retrospective surveillance study on enterovirus D68 was performed in Beijing, China, following the largest and most widespread EV-D68 infection, which occurred in the USA. From January 2011 to July 2015, EV-D68 was identified in 12 individuals with respiratory infections in Beijing, China. The phylogenetic relationships based on the genomic sequence alignment showed that there were two lineages circulating in Beijing from 2011 to 2015. Eight EV-D68 strains belonged to group 1 and four belonged to group 3...
September 2016: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/27749661/a-4-year-study-on-epidemiologic-and-molecular-characteristics-of-human-parechoviruses-and-enteroviruses-circulating-in-children-younger-than-5-years-in-northern-italy
#13
Laura Bubba, Marianna Martinelli, Laura Pellegrinelli, Valeria Primache, Elisabetta Tanzi, Elena Pariani, Sandro Binda
BACKGROUND: Human parechovirus (HPeV) and enterovirus (EV) infections are widespread and can lead to a broad range of symptoms, from the common cold to severe disease (SD). Because of the lack of Italian data, this 4-year retrospective cross-sectional study aimed to investigate the frequency, seasonality and molecular characteristics of EV and HPeV circulating in children younger than 5 years. METHODS: A total of 812 samples were collected from children ≤5 years (56...
January 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27739205/enterovirus-d68-respiratory-infections
#14
David Isaacs
No abstract text is available yet for this article.
October 2016: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/27673031/poster-274-the-rehabilitation-and-recovery-of-an-adult-survivor-of-enterovirus-d68-encephalomyelitis-a-case-report
#15
Lauren T Shapiro
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27668922/system-stresses-in-2-pediatric-emergency-departments-and-2-pediatric-urgent-care-centers-during-the-2014-enterovirus-d68-outbreak
#16
Gregory P Conners, Stacy J Doyle, Milton A Fowler, Lisa L Schroeder, Thomas W Tryon
OBJECTIVE: To describe the association of an unprecedented large-scale Enterovirus-D68 outbreak in 2014 with changes in patient volume and acuity and system stress in 2 pediatric emergency departments and 2 pediatric urgent care centers of a single children's hospital. METHODS: We compared measures of patient volume, acuity, and system stress during the 2014 Enterovirus-D68 outbreak and the corresponding dates of the previous year. RESULTS: Both settings experienced large census increases during the Enterovirus-D68 outbreak; patient census increased significantly more in the pediatric urgent care setting (20...
September 23, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27666816/guillain-barr%C3%A3-syndrome
#17
REVIEW
Susanna Esposito, Maria Roberta Longo
The term Guillain-Barré syndrome (GBS), the most frequent cause of acute paralytic neuropathy, covers a number of recognisably distinct variants. The exact cause of GBS is unknown, but 50-70% of cases appear 1-2weeks after a respiratory or gastrointestinal infection, or another immune stimulus that induces an aberrant autoimmune response targeting peripheral nerves and their spinal roots. The interplay between the microbial and host factors that dictate whether and how the immune response shifts towards autoreactivity is still unclear, and nothing is known about the genetic and environmental factors that affect an individual's susceptibility to the disease...
January 2017: Autoimmunity Reviews
https://www.readbyqxmd.com/read/27660916/upsurge-of-enterovirus-d68-the-netherlands-2016
#18
Marjolein Knoester, Elisabeth H Schölvinck, Randy Poelman, Sylvia Smit, Clementien L Vermont, Hubert G M Niesters, Coretta C Van Leer-Buter
In June and July 2016, we identified 8 adults and 17 children with respiratory enterovirus D68 infections. Thirteen children required intensive care unit admission because of respiratory insufficiency, and 1 had concomitant acute flaccid myelitis. Phylogenetic analysis showed that all of 20 sequences obtained belong to the recently described clade B3.
January 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/27660790/identification-and-whole-genome-sequencing-of-four-enterovirus-d68-strains-in-southern-china-in-late-2015
#19
Long Chen, Lei Shi, Hong Yang, Da-Yong Gu, Jun Meng, Yun-Qing Xu, Xiang-Jie Yao, Hai-Long Zhang, Jin-Quan Cheng, Han-Wu Ma, Ren-Li Zhang, Ya-Qing He
Four enterovirus D68 (EV-D68) strains from four children with influenza-like illness were identified in Shenzhen, southern China, in late 2015. Here, we announce the availability of these viral genomes in GenBank. The genomic sequences of these EV-D68 strains showed the closest phylogenetic relationship to strains from northern China.
2016: Genome Announcements
https://www.readbyqxmd.com/read/27610028/respiratory-presentation-of-pediatric-patients-in-the-2014-enterovirus-d68-outbreak
#20
Georgina Martin, Rachel Li, Victoria E Cook, Matthew Carwana, Peter Tilley, Laura Sauve, Patrick Tang, Akshat Kapur, Connie L Yang
Background. In the fall of 2014, a North American outbreak of enterovirus D68 resulted in a significant number of pediatric hospital admissions for respiratory illness throughout North America. This study characterized the clinical presentation and risk factors for a severe clinical course in children admitted to British Columbia Children's Hospital during the 2014 outbreak. Methods. Retrospective chart review of patients with confirmed EV-D68 infection admitted to BCCH with respiratory symptoms in the fall of 2014...
2016: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
keyword
keyword
39060
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"