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https://www.readbyqxmd.com/read/29691984/identification-of-novel-cyp4v2-genotypes-associated-with-bietti-crystalline-dystrophy-and-atypical-anterior-segment-phenotypes-in-spanish-patients
#1
Gerardo Pedro García-García, Magdalena Martínez-Rubio, Medina-Azahara Moya-Moya, Juan José Pérez-Santonja, Julio Escribano
PURPOSE: To identify the spectrum of disease-causing CYP4V2 variants in Spanish patients with clinically diagnosed Bietti crystalline dystrophy (BCD) over an 8-year period and to analyse the phenotype-genotype correlation of the identified variants. METHODS: Four unrelated Spanish probands with a clinical diagnosis of BCD were recruited. Ophthalmological examination included visual acuity (VA), slit lamp examination, in vivo corneal confocal microscopy, funduscopy and fluoresceinic angiography...
April 25, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29690290/on-the-dumping-ground-genus-scotaena-klug-1810-hymenoptera-tiphiidae-thynninae-phylogeny-taxonomy-and-geographic-distribution
#2
Fernando Henrique Carnimeo, Fernando Barbosa Noll
The Neotropical thynnine genus Scotaena is revised and a cladistic analysis is presented. The analysis, conducted from 75 morphological characters of 31 terminal taxa, returned a single tree under equal weighting. The monophyly of Scotaena was not recovered. Three new genera and five new species are described: Kaysara gen. nov., Pseudoscotaena gen. nov. and Pampathynnus gen. nov., Scotaena reversa sp. nov., Kaysara laterolata sp. nov., Kaysara apiciconcava sp. nov., Kaysara marginoplicata sp. nov. and Kaysara levicrenata sp...
March 22, 2018: Zootaxa
https://www.readbyqxmd.com/read/29684285/imaging-lung-function-abnormalities-in-primary-ciliary-dyskinesia-using-hyperpolarised-gas-ventilation-mri
#3
Laurie J Smith, Noreen West, David Hughes, Helen Marshall, Christopher S Johns, Neil J Stewart, Ho-Fung Chan, Madhwesha Rao, David J Capener, Jody Bray, Guilhem J Collier, Paul Jc Hughes, Graham Norquay, Lynne Schofield, Phil Chetcuti, Eduardo Moya, Jim M Wild
No abstract text is available yet for this article.
April 23, 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29683848/effects-of-hiv-art-and-prebiotics-on-the-active-fraction-of-the-gut-microbiota
#4
Simon Deusch, Sergio Serrano-Villar, David Rojo, Mónica Martínez-Martínez, Rafael Bargiela, Jorge F Vázquez-Castellanos, Talía Sainz, Coral Barbas, Andrés Moya, Santiago Moreno, María J Gosalbes, Vicente Estrada, Jana Seifert, Manuel Ferrer
OBJECTIVE: In a recent blinded randomized study, we found that in HIV individuals a short supplementation with prebiotics (scGOS/lcFOS/glutamine) ameliorates dysbiosis of total gut bacteria, particularly among viremic untreated patients. Our study goal was to determine the fraction of the microbiota that becomes active during the intervention and that could provide additional functional information. DESIGN: A total of six healthy individuals, and 16 HIV-infected patients comprising viremic untreated patients (n = 5) and antiretroviral therapy-treated (ART) patients that are further divided into immunological responders (n = 7) and immunological nonresponders (n = 4) completed the 6-week course of prebiotic treatment, including six patients receiving a placebo...
April 19, 2018: AIDS
https://www.readbyqxmd.com/read/29683544/high-folate-levels-are-not-associated-with-increased-malaria-risk-but-with-reduced-anemia-rates-in-the-context-of-high-dosed-folate-supplements-and-intermittent-preventive-treatment-against-malaria-in-pregnancy-with-sulphadoxine-pirymethamine-in-benin
#5
Violeta Moya-Alvarez, Smaila Ouédraogo, Manfred Accrombessi, Michel Cot
OBJECTIVES: To investigate if high-dosed folate supplements might diminish the efficacy of malaria intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) in a cohort of pregnant women in Benin, where malaria is holoendemic. METHODS: We followed 318 women during the entire pregnancy and analyzed hematological and P.falciparum indicators in the context of an intermittent preventive treatment trial in Benin. During the follow-up women received two-dose IPTp (1500/75 mg of SP per dose) at the maternity clinic, and 600 mg of albendazole, 200 mg ferrous sulfate and 5 mg folic acid per day for home treatment...
April 23, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29675200/probing-the-origin-of-the-giant-magnetic-anisotropy-in-trigonal-bipyramidal-ni-ii-under-high-pressure
#6
Gavin A Craig, Arup Sarkar, Christopher H Woodall, Moya A Hay, Katie E R Marriott, Konstantin V Kamenev, Stephen A Moggach, Euan K Brechin, Simon Parsons, Gopalan Rajaraman, Mark Murrie
Understanding and controlling magnetic anisotropy at the level of a single metal ion is vital if the miniaturisation of data storage is to continue to evolve into transformative technologies. Magnetic anisotropy is essential for a molecule-based magnetic memory as it pins the magnetic moment of a metal ion along the easy axis. Devices will require deposition of magnetic molecules on surfaces, where changes in molecular structure can significantly alter magnetic properties. Furthermore, if we are to use coordination complexes with high magnetic anisotropy as building blocks for larger systems we need to know how magnetic anisotropy is affected by structural distortions...
February 14, 2018: Chemical Science
https://www.readbyqxmd.com/read/29674092/humic-acid-attenuation-of-silver-nanoparticle-toxicity-by-ion-complexation-and-the-formation-of-a-ag-3-coating
#7
Paolin Rocio Cáceres-Vélez, Maria Luiza Fascineli, Marcelo Henrique Sousa, Cesar Koppe Grisolia, Luis Yate, Paulo Eduardo Narcizo de Souza, Irina Estrela-Lopis, Sergio Moya, Ricardo Bentes Azevedo
The use of silver nanoparticles (AgNPs) result in an inevitable contact with aquatic environments. Here we study the behavior of AgNPs and the developmental toxicity in zebrafish embryos exposed to these nanoparticles (0-10 mg/L) with and without the presence of HA (20 mg/L), using zebrafish facility water (ZFW) and zebrafish growing media (ZGM). The presence of cations and HA gave rise to a decrease in Ag ion release and ζ-potential, an increase in the hydrodynamic diameter and oxidation of the AgNP surface...
April 11, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29670710/effect-of-the-lack-of-primary-stability-in-the-survival-of-dental-implants
#8
Carlos Cobo-Vázquez, David Reininger, Pedro Molinero-Mourelle, José González-Serrano, Blanca Guisado-Moya, Juan López-Quiles
Background: The survival of dental implants has been linked to primary stability. The aim of this study is to analyse the factors that influence the survival of dental implants placed without primary stability. Material and Methods: A cohort study of implants placed without primary stability was carried out between September 2011 and July 2016. All cases with registered information on the patient and surgical intervention were used. Cases that did not have a 12-month follow-up after implant placement were excluded...
January 2018: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29664502/hospital-acquired-hyponatremia-does-the-type-of-fluid-therapy-affect-children-admitted-to-intensive-care
#9
Pilar Velasco, Andrés J Alcaraz, Niki Oikonomopoulou, Marina Benito, Raquel Moya, Álvaro Sánchez
INTRODUCTION: The objective of this study was to evaluate the association between the type of initial fluid therapy used (isotonic or hypotonic solutions) and the development of hyponatremia, the plas ma chlorine values and the tolerance of venous access. PATIENTS AND METHOD: Retrospective cohort study in a Pediatric Intensive Care Unit (PICU) of a high complexity hospital. There were included children younger than 15 years old hospitalized during the first semester of 2010 and 2013 who recei ved intravenous maintenance fluid therapy, excluding patients undergoing cardiac surgery, kidney transplant and admissions that lasted less than 24 hours...
February 2018: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/29659762/activation-of-%C3%AF-20-dependent-recombination-and-horizontal-gene-transfer-in-mycoplasma-genitalium
#10
Sergi Torres-Puig, Carlos Martínez-Torró, Ignasi Granero-Moya, Enrique Querol, Jaume Piñol, Oscar Q Pich
In the human pathogen Mycoplasma genitalium, homologous recombination is under the control of σ20, an alternative sigma factor that boosts the generation of genetic and antigenic diversity in the population. Under laboratory growth conditions, σ20 activation is rare and the factors governing its intermittent activity are unknown. Two σ20-regulated genes, rrlA and rrlB, showed to be important for recombination of homologous DNA sequences in this bacterium. Herein, we demonstrate that rrlA and rrlB code for two small proteins that participate in a feed-forward loop essential for σ20 function...
April 11, 2018: DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes
https://www.readbyqxmd.com/read/29659472/evaluation-and-management-of-abdominal-stab-wounds-a-western-trauma-association-critical-decisions-algorithm
#11
Matthew J Martin, Carlos V R Brown, David V Schatz, Hasan Alam, Karen Brasel, Carl Hauser, Marc de Moya, Ernest E Moore, Susan Rowell, Gary Vercruysse, Bonny Baron, Kenji Inaba
No abstract text is available yet for this article.
April 13, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29652727/a-rare-case-of-gallbladder-and-common-bile-duct-benign-capillary-hemangioma-in-a-toddler
#12
Abdul R Shahein, Diana Moya, Andrew Buckley, John McGrath, Rafal Kozielski, Robert D Baker, Susan S Baker
No abstract text is available yet for this article.
April 12, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29622196/simultaneous-determination-of-carotenoids-tocopherols-retinol-and-cholesterol-in-ovine-lyophilised-samples-of-milk-meat-and-liver-and-in-unprocessed-raw-samples-of-fat
#13
J R Bertolín, M Joy, P J Rufino-Moya, S Lobón, M Blanco
An accurate, fast, economic and simple method to determine carotenoids, tocopherols, retinol and cholesterol in lyophilised samples of ovine milk, muscle and liver and raw samples of fat, which are difficult to lyophilise, is sought. Those analytes have been studied in animal tissues to trace forage feeding and unhealthy contents. The sample treatment consisted of mild overnight saponification, liquid-liquid extraction, evaporation with vacuum evaporator and redissolution. The quantification of the different analytes was performed by the use of ultra-high performance liquid chromatography with diode-array detector for carotenoids, retinol and cholesterol and fluorescence detector for tocopherols...
August 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29620612/tofacitinib-halts-progression-of-graft-dysfunction-in-a-rat-model-of-mixed-cellular-and-humoral-rejection
#14
Jordi Rovira, María J Ramírez-Bajo, Elisenda Banon-Maneus, Marta Lazo-Rodríguez, Daniel Moya-Rull, Natalia Hierro-Garcia, Valeria Tubita, Gastón J Piñeiro, Ignacio Revuelta, Pedro Ventura-Aguiar, David Cucchiari, Federico Oppenheimer, Mercè Brunet, Josep M Campistol, Fritz Diekmann
BACKGROUND: The progression from acute to chronic antibody-mediated rejection in kidney transplant recipients is usually not prevented by current therapeutic options. Here, we investigated whether the use of tofacinitib, a Janus kinase 3 inhibitor, was capable of preventing the progression of allograft dysfunction in a Fisher-to-Lewis rat model of kidney transplantation. METHODS: Rats were treated from the third week after transplantation in order to allow the development of rejection...
April 3, 2018: Transplantation
https://www.readbyqxmd.com/read/29616241/surfactants-as-mesogenic-agents-in-layer-by-layer-assembled-polyelectrolyte-surfactant-multilayers-nanoarchitectured-soft-thin-films-displaying-a-tailored-mesostructure
#15
Esteban Piccinini, Jimena S Tuninetti, Joseba Irigoyen Otamendi, Sergio E Moya, Marcelo Ceolín, Fernando Battaglini, Omar Azzaroni
Interfacial supramolecular architectures displaying mesoscale organized components are of fundamental importance for developing materials with novel or optimized properties. Nevertheless, engineering the multilayer assembly of different building blocks onto a surface and exerting control over the internal mesostructure of the resulting film is still a challenging task in materials science. In the present work we demonstrate that the integration of surfactants (as mesogenic agents) into layer-by-layer (LbL) assembled polyelectrolyte multilayers offers a straightforward approach to control the internal film organization at the mesoscale level...
April 4, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29611585/growth-modulating-agents-for-the-synthesis-of-al-mof-type-materials-based-on-assembled-1d-structural-subdomains
#16
José María Moreno, Alexandra Velty, José A Vidal-Moya, Urbano Díaz, Avelino Corma
Novel aluminium MOF-type materials structured by 1D subdomains, such as organic-inorganic nanoribbons, were synthesized by modifying the conditions of solvothermal synthesis and the nature of the solvents in the presence of aryl monocarboxylate linkers with long alkyl chains, which acted as growth-modulating agents. Specifically, three different families of materials were prepared with various morphological characteristics: (i) isoreticular MIL-53(Al)-type materials, (ii) mesoscopic metalorganic structures and (iii) lamellar aluminium MOFs...
April 3, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29610534/to-list-or-not-to-list-the-value-and-detriment-of-freelisting-in-ethnobotanical-studies
#17
Narel Y Paniagua Zambrana, Rainer W Bussmann, Robbie E Hart, Araceli L Moya Huanca, Gere Ortiz Soria, Milton Ortiz Vaca, David Ortiz Álvarez, Jorge Soria Morán, María Soria Morán, Saúl Chávez, Bertha Chávez Moreno, Gualberto Chávez Moreno, Oscar Roca, Erlin Siripi
Although freelisting and semi-structured interviews are widespread methods in ethnobotany, few studies quantitatively examine how these methods may bias results. Using a comprehensive ethnobotanical inventory of palm species, uses and names in the Chácobo tribe of Bolivia, we show that interviews elicit more items than freelists, but the effect is sensitive to sample size, item type and data categorization. This implies that even subtle methodological choices may greatly affect reported results.
April 2, 2018: Nature Plants
https://www.readbyqxmd.com/read/29606747/assessment-of-the-reducing-capacity-of-processed-fruit-juices-with-the-copper-i-4-4-dicarboxy-2-2-biquinoline-complexes
#18
Letícia Cristina Viana Miguel, Ana Beatriz Ramos de Oliveira Pinn, Horacio Dorigan Moya
An alternative method for quantification of the total reducing capacity (TRC) of processed ready-to-drink fruit juices (orange, grape, peach, mango, cashew, strawberry, apple and guava) is suggested. The spectrophotometric procedure is based on the reduction of Cu(II) to Cu(I) by antioxidants (present in the samples) in aqueous buffered solution (pH 7.0), containing 4,4'-dicarboxy-2,2'-biquinoline acid (H2 BCA), yielding the [Formula: see text] complexes. The absorbance values at 558 nm (A558 nm ) of the [Formula: see text] complexes obtained with juice samples were compared with A558 nm values of the same complexes obtained with a standard ascorbic acid solution and used to quantify and express the reducing capacity of each sample...
April 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29604094/cardiac-resynchronization-therapy-is-associated-with-a-reduction-in-icd-therapies-while-improves-ventricular-function
#19
Enrique Galve, Gerard Oristrell, Gabriel Acosta, Aida Ribera-Solé, Àngel Moya-Mitjans, Ignacio Ferreira-González, Jordi Pérez-Rodon, David García-Dorado
BACKGROUND: Repeated implantable cardioverter-defibrillator (ICD) therapies cause myocardial damage and thus, an increased risk of arrhythmias and mortality. HYPOTHESIS: Cardiac resynchronization therapy-defibrillator (CRT-D) reduces the number of appropriate therapies in patients with left ventricular dysfunction (LVEF < 50%). METHODS: The retrospective study involved 175 consecutive patients (age 64.6±10.4 years, 86.9% men) with reduced LVEF 27...
March 31, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29602766/predictors-of-acute-failure-ablation-of-intra-atrial-re-entrant-tachycardia-in-patients-with-congenital-heart-disease-cardiac-disease-atypical-flutter-and-previous-atrial-fibrillation
#20
Ivo Roca-Luque, Nuria Rivas-Gándara, Laura Dos-Subirà, Jaume Francisco-Pascual, Antònia Pijuan-Domenech, Jordi Pérez-Rodon, Alba Santos-Ortega, Ferran Roses-Noguer, Ignacio Ferreira-Gonzalez, David García-Dorado García, Angel Moya Mitjans
BACKGROUND: Intra-atrial re-entrant tachycardia (IART) in patients with congenital heart disease (CHD) increases morbidity and mortality. Radiofrequency catheter ablation has evolved as the first-line treatment. The aim of this study was to analyze the acute success and to identify predictors of failed IART radiofrequency catheter ablation in CHD. METHODS AND RESULTS: The observational study included all consecutive patients with CHD who underwent a first ablation procedure for IART at a single center from January 2009 to December 2015 (94 patients, 39...
March 30, 2018: Journal of the American Heart Association
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