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Thais Caldara Mussi, Yves Bohrer Costa, Marcos Takeo Obara, Marcos Roberto Gomes de Queiroz, Rodrigo Gobbo Garcia, José Antonio Domingos Cianciarulo Longo, Gustavo Caserta Lemos, Ronaldo Hueb Baroni
Objective: To describe the imaging findings of prostatic tumors nonadenocarcinoma on multiparametric magnetic resonance imaging. Methods: A total of 200 patients underwented multiparametric magnetic resonance imaging of the prostate for screening for prostate cancer, from August 2013 to September 2014, followed by biopsy with ultrasound/magnetic resonance imaging fusion. Results: We found three pathologic proved cases of prostatic pure leiomyomas (0...
July 2016: Einstein
Pedro Nazareth Aguiar, Gustavo Trautman Stock, Gilberto de Lima Lopes, Michelle Samora de Almeida, Hakaru Tadokoro, Bárbara de Souza Gutierres, Douglas Antônio Rodrigues
Objective: To assess aspects related to cancer in indigenous population. Methods: This is a retrospective study developed in a public university hospital. We included patients with 18 or more years of age, diagnosed with solid tumors, and followed between 2005 and 2015. Clinical features were assessed by descriptive statistics, and survival was evaluated by Kaplan-Meier curves and multivariate Cox regression. Results: Fifty patients were included...
July 2016: Einstein
Victor Kuete, Joachim K Dzotam, Igor K Voukeng, Aimé G Fankam, Thomas Efferth
BACKGROUND: Cancer cells rapidly acquire resistance leading to treatment failures. In the present study, we have evaluated the cytotoxicity of 17 methanol extracts from 11 Cameroonian medicinal plants against the sensitive leukemia CCRF-CEM cells and the best ones were further tested on a panel of 8 other human cancer cell lines, including various MDR phenotypes as well as against the normal AML12 hepatocytes. METHODS: The cytotoxicity of the extracts was determined using a resazurin reduction assay meanwhile flow cytometry was used to measure cell cycle, apoptosis, mitochondrial membrane potential (MMP), and reactive oxygen species...
2016: SpringerPlus
Franziska Conrad, Thomas Winkens, Martin Kaatz, Steven Goetze, Martin Freesmeyer
HINTERGRUND UND ZIELE: Bei der (18) F-Fluordeoxyglucose-Positronenemissionstomographie/Computertomographie (FDG-PET/CT) ergeben sich häufig Zufallsbefunde. In der vorliegenden Studie konzentrierten wir uns auf mittels FDG-PET/CT erhaltene Zufallsbefunde bei Patienten mit kutanem Melanom und überprüften deren Relevanz hinsichtlich weiterer diagnostischer Maßnahmen und Interventionen. PATIENTEN UND METHODEN: Die Krankenakten von 181 konsekutiven Melanom-Patienten wurden retrospektiv ausgewertet, um das Management von Zufallsbefunden zu dokumentieren...
August 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
R Sánchez-Salas, E Linares Espinós
No abstract text is available yet for this article.
July 2016: Archivos Españoles de Urología
J M Martínez-Jabaloyas, A Castelló-Porcar, A C González-Baena, J M Cózar-Olmo, B Miñana-López, F Gómez-Veiga, A Rodriguez-Antolín
OBJECTIVE: The aim of this study is to determine which cancer and demographic criteria influence the indication for surgery (radical prostatectomy) or radiation therapy (external or brachytherapy) in the treatment of prostate cancer. MATERIAL AND METHODS: An analysis of the 2714 patients of the 2010 National Prostate Cancer Registry treated with curative intent. The analysed variables were age, prostate-specific antigen (PSA), prostate volume, the number of biopsy cores, the percentage of positive cores, the stage, Gleason score, the type of pathologist, the presence of perineural invasion and the study centre...
October 2016: Actas Urologicas Españolas
Afra Khiralla, Ietidal E Mohamed, Tzvetomira Tzanova, Hervé Schohn, Sophie Slezack-Deschaumes, Alain Hehn, Philippe André, Gaëlle Carre, Rosella Spina, Annelise Lobstein, Sakina Yagi, Dominique Laurain-Mattar
In this study, we isolated 15 endophytic fungi from five Sudanese medicinal plants. Each fungal endophytic strain was identified by sequencing of internal transcribed spacer (ITS) regions of rDNA. Ethyl acetate extracts were prepared from each endophyte cultivated in vitro and tested for their respective antibacterial activities and antiproliferative activities against human cancer cells. Antibacterial screening was carried out against two bacterial strains: Gram-negative Escherichia coli and Gram-positive methicillin-resistant Staphylococcus aureus, by the broth dilution method...
June 2016: FEMS Microbiology Letters
H Soto, M Marquez, K Sanchez
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
A Lara, D Godinez, A Fonseca, F Lemus
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
R Timana-Ruiz, A Sobrevilla-Ricci, R Mosqueira-Lovón, A Gutierrez-Aguado, S Escobedo-Palza
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
A Yepes Correa, R Gómez Wolff, J P Jiménez Ochoa, C Lopera Carvajal, J Picó Guzmán, H I García García
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
J C Villa, J Espinosa, R Gomez, V Sanchez, R Lopez, R Galan, M D Pineda, M Perez
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
M Daniaux, T Auer, T De Zordo, D Junker, W Santner, M Hubalek, W Jaschke, F Aigner
UNLABELLED: Typically both breast and prostate cancer present as tissue with decreased elasticity. Palpation is the oldest technique of tumor detection in both organs and is based on this principle. Thus an operator can grade a palpable mass as suspicious for cancer. Strain elastography as modern ultrasound technique allows the visualization of tissue elasticity in a color coded elastogram and can be understood as technical finger. The following article shows similarities and differences of ultrasound strain elastography in the diagnosis of breast and prostate cancer...
March 2016: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
Josephine Rathenborg, Margrethe Andersen, Reza Zemani, Bo Elle, Lars Lund
We present a case of persisting macroscopic haematuria in a patient with severe co-morbidity and need of blood transfusion. With a combination of selective embolisation of the internal pudendal artery and transurethral microwave therapy in local anaesthesia, the patient was treated successfully.
August 10, 2015: Ugeskrift for Laeger
Raman Tanwar, Nikhil Khattar, Rajeev Sood, Arun Makkar
INTRODUCTION: Information derived from social media sources is being used to save lives and take vital life altering decisions. You Tube is one of the most widely used social media for seeking medical information. Quality of information available to patients and medical professionals on YouTube with regards to benign prostatic hyperplasia (BPH), a common urological condition, assessed. MATERIALS AND METHODS: First 1 00 videos results on BPH were analysed by three independent observers and graded based on the quality of information provided using an indigenous grading system of five points ranging from not useful to Informative for the Medical Professional...
July 2015: Recenti Progressi in Medicina
T Franiel, P Asbach, U Teichgräber, B Hamm, S Foller
UNLABELLED: New technical and clinical developments of sonography and magnetic resonance imaging include improved detection, localization and staging as well as active surveillance of prostate cancer. Multiparametric MRI can best answer these typical clinical questions. However, ultrasound elastography seems to be suitable for the detection of significant prostate cancer as well. The structured reporting system for multiparametric MRI of the prostate according to PI-RADS Version 1 led to improved and reproducible diagnosis of prostate cancer...
September 2015: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
F Herranz Amo, C Hernández Fernández, J M Cózar Olmo, B Miñana López, F Gómez-Veiga, A Rodríguez-Antolín, E Pedrosa
OBJECTIVE: To assess the adherence to the recommendations of the 2009 clinical guidelines in the implementation of lymphadenectomy during radical prostatectomy and analysis of the variables that influence this decision in the 2010 National Prostate Cancer Registry. MATERIAL AND METHOD: Analysis of 1,272 patients who underwent prostatectomy in 25 national hospitals. Patient classification according to the pathological node-positive (pN+) risk criteria included in the clinical guidelines of the European Association of Urology (EAU) and National Comprehensive Cancer Network (NCCN)...
November 2015: Actas Urologicas Españolas
Joan Morote, Xavier Maldonado, Rafael Morales-Bárrera
The Vall d'Hebron multidisciplinary prostate cancer (PC) team reviews recent advances in the management of this neoplasm. Screening studies with long follow-up show a reduction in mortality, whereas active surveillance is emerging as a therapeutic approach of non-aggressive cancers. New markers increase the specificity of PSA and also allow targeting suspected aggressive cancers. Multiparametric magnetic resonance (mMRI) has emerged as the most effective method in the selection of patients for biopsy and also for local tumor staging...
February 5, 2016: Medicina Clínica
Jorge Navarro-Pérez, Salvador Peiró, Francisco Brotons-Muntó, Emilio López-Alcina, Arcadio Real-Romaguera
OBJECTIVE: To assess quality of care indicators for benign prostatic hyperplasia (BPH), and to evaluate their strengths and weaknesses for incorporation into health information systems. DESIGN: Structured expert meeting, using procedures adapted from the nominal group techniques and the Rand consensus method. SETTING: Valencian School of Health Studies. PARTICIPANTS AND/OR CONTEXTS: Forty panellists (74% doctors, 70% from primary care settings) with experience in the management of BPH from 15 departments of the Valencia Health Agency...
May 2014: Atencion Primaria
H Akdere, K M Burgazli, T Aktoz, A Acikgoz, M Mericliler, A S Gozen
INTRODUCTION: In our study, the efficiency and reliability of lidocaine (1 cc/1%) application during transrectal ultrasound-guided (TRUS) prostate biopsy to levatores prostate was studied. Levatores prostate was visualized on a cadaver dissection previously. PATIENTS AND METHODS: Eighty outpatients with lower urinary tract complaints or were suspected clinically to have prostate cancer were submitted to TRUS-guided prostate biopsy. The ages of outpatients were ranging from 45 to 81...
November 2013: European Review for Medical and Pharmacological Sciences
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