keyword
https://read.qxmd.com/read/38535062/the-role-of-sars-cov-2-nucleocapsidic-antigen-and-krebs-von-den-lungen-6-serum-levels-in-predicting-covid-19-pneumonia-outcome
#1
JOURNAL ARTICLE
Stefano Sanduzzi Zamparelli, Vincenzo Fucci, Gaetano Rea, Francesco Perna, Marialuisa Bocchino, Alessandro Sanduzzi Zamparelli
BACKGROUND: The COVID-19 pandemic caused by SARS-CoV-2 continues to pose a significant threat worldwide, with severe cases leading to hospitalization and death. This study aims to evaluate the potential use of serum nucleocapsid antigen (NAg) and Krebs von den Lungen-6 glycoprotein (KL-6) as biomarkers of severe COVID-19 and to investigate their correlation with clinical, radiological, and biochemical parameters. METHODS: This retrospective study included 128 patients with confirmed SARS-CoV-2 infection admitted to a Neapolitan hospital in Italy between October 2020 and July 2021...
March 18, 2024: Diagnostics
https://read.qxmd.com/read/38534920/sex-based-analysis-of-quality-indicators-of-end-of-life-care-in-gastrointestinal-malignancies
#2
JOURNAL ARTICLE
Caitlin S Lees, Hsien Seow, Kelvin K W Chan, Anastasia Gayowsky, Shaila J Merchant, Aynharan Sinnarajah
Indices of aggressive or supportive end-of-life (EOL) care are used to evaluate health services quality. Disparities according to sex were previously described, with studies showing that male sex is associated with aggressive EOL care. This is a secondary analysis of 69,983 patients who died of a GI malignancy in Ontario between 2006 and 2018. Quality indices from the last 14-30 days of life and aggregate measures for aggressive and supportive EOL care were derived from administrative data. Hospitalizations, emergency department use, intensive care unit admissions, and receipt of chemotherapy were considered indices of aggressive care, while physician house call and palliative home care were considered indices of supportive care...
February 22, 2024: Current Oncology
https://read.qxmd.com/read/38533775/impact-of-a-nationwide-medication-history-sharing-program-on-the-care-process-and-end-user-experience-in-a-tertiary-teaching-hospital-cohort-study-and-cross-sectional-study
#3
JOURNAL ARTICLE
Jungwon Cho, Sooyoung Yoo, Eunkyung Euni Lee, Ho-Young Lee
BACKGROUND: Timely and comprehensive collection of a patient's medication history in the emergency department (ED) is crucial for optimizing health care delivery. The implementation of a medication history sharing program, titled "Patient's In-home Medications at a Glance," in a tertiary teaching hospital aimed to efficiently collect and display nationwide medication histories for patients' initial hospital visits. OBJECTIVE: As an evaluation was necessary to provide a balanced picture of the program, we aimed to evaluate both care process outcomes and humanistic outcomes encompassing end-user experience of physicians and pharmacists...
March 20, 2024: JMIR Medical Informatics
https://read.qxmd.com/read/38533612/dying-at-home-what-is-needed-findings-from-a-nationwide-retrospective-cross-sectional-online-survey-of-bereaved-people-in-germany
#4
JOURNAL ARTICLE
Alina Kasdorf, Raymond Voltz, Julia Strupp
OBJECTIVES: According to the "Last Year of Life in Cologne" study, 68% of patients with a serious and terminal illness wanted to die at home, but 42% died in hospital. Only 1 in 5 died at home. Most people want to spend their last days and hours at home, but the reality is that this is not always possible. Recommendations are needed on how best to support families to enable people to die at home - if this is their preferred place of death. Our aim was to identify the factors that make it possible for people to die at home and to analyze factors of dying at home...
March 27, 2024: Palliative & Supportive Care
https://read.qxmd.com/read/38533291/accuracy-of-a-non-invasive-home-glucose-monitor-for-measurement-of-blood-glucose
#5
JOURNAL ARTICLE
Himel Mondal, Sairavi Kiran Biri, Neha Pipil, Shaikat Mondal
INTRODUCTION: Patients with diabetes mellitus monitor their blood glucose at home with monitors that require a drop of blood or use a continuous glucose monitoring device that implants a small needle in the body. However, both cause discomfort to the patients which may inhibit them for regular blood glucose checks. Photoplethysmogram (PPG) sensing technology is an approach for non-invasive blood glucose measurement and PPG sensors can be used to predict hypoglycaemic episodes. InChcek is a PPG-based non-invasive glucose monitor...
2024: Indian Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38532989/access-and-cost-of-services-for-autistic-children-and-adults-in-italy-a-carers-perspective
#6
JOURNAL ARTICLE
Martina Micai, Francesca Fulceri, Tommaso Salvitti, Giovanna Romano, Maria Luisa Scattoni
BACKGROUND: Limited information exists on autistic service access and costs in Italy. OBJECTIVES: This study aims to investigate access to educational, healthcare, social, and related services for autistic individuals in Italy as part of the Autism Spectrum Disorder in the European Union (ASDEU) project. METHODS: Italian carers of autistic individuals completed an online survey regarding services and costs in the 6 months before completion...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38531391/increased-rates-of-hypertensive-disorders-of-pregnancy-during-the-covid-19-pandemic
#7
JOURNAL ARTICLE
Colleen Sinnott, Taylor S Freret, Mark A Clapp, Sarah E Little
OBJECTIVE: Hypertensive disorders of pregnancy (HDP) are common complications associated with severe maternal and neonatal morbidity. One goal of prenatal care, especially at term, is to screen for HDP. As treatment of HDP centers on delivery when appropriate, timely diagnosis is crucial. We postulated that reduced in-person visits during the COVID-19 pandemic may have resulted in delayed diagnosis of HDP with concomitant higher rates of maternal morbidity. We sought to investigate the prevalence of HDP during the COVID-19 pandemic, as well as median gestational age at time of delivery as compared to the pre-pandemic median...
March 26, 2024: American Journal of Perinatology
https://read.qxmd.com/read/38530853/local-scale-phylodynamics-reveal-differential-community-impact-of-sars-cov-2-in-a-metropolitan-us-county
#8
JOURNAL ARTICLE
Miguel I Paredes, Amanda C Perofsky, Lauren Frisbie, Louise H Moncla, Pavitra Roychoudhury, Hong Xie, Shah A Mohamed Bakhash, Kevin Kong, Isabel Arnould, Tien V Nguyen, Seffir T Wendm, Pooneh Hajian, Sean Ellis, Patrick C Mathias, Alexander L Greninger, Lea M Starita, Chris D Frazar, Erica Ryke, Weizhi Zhong, Luis Gamboa, Machiko Threlkeld, Jover Lee, Jeremy Stone, Evan McDermot, Melissa Truong, Jay Shendure, Hanna N Oltean, Cécile Viboud, Helen Chu, Nicola F Müller, Trevor Bedford
SARS-CoV-2 transmission is largely driven by heterogeneous dynamics at a local scale, leaving local health departments to design interventions with limited information. We analyzed SARS-CoV-2 genomes sampled between February 2020 and March 2022 jointly with epidemiological and cell phone mobility data to investigate fine scale spatiotemporal SARS-CoV-2 transmission dynamics in King County, Washington, a diverse, metropolitan US county. We applied an approximate structured coalescent approach to model transmission within and between North King County and South King County alongside the rate of outside introductions into the county...
March 26, 2024: PLoS Pathogens
https://read.qxmd.com/read/38530599/how-well-do-ed-physician-practices-align-with-the-caep-acute-atrial-fibrillation-checklist-for-stroke-prevention-and-disposition
#9
JOURNAL ARTICLE
Samara Adler, Amanda M S Mattice, Debra Eagles, Krishan Yadav, Sean Hui, Althaf Azward, Nikesh Pandey, Ian Stiell
OBJECTIVES: Acute atrial fibrillation (AF)/flutter (AFL) is a common emergency department (ED) presentation. In 2021, an updated version of CAEP's Acute AF/AFL Best Practices Checklist was published, seeking to guide management. We assessed the alignment with and safety of application of the Checklist, regarding stroke prevention and disposition. METHODS: This health records review included adults presenting to two tertiary care academic EDs between January and August 2022 with a diagnosis of acute AF/AFL...
March 26, 2024: CJEM
https://read.qxmd.com/read/38530349/equity-centered-postdischarge-support-for-medicaid-insured-people-protocol-for-a-type-1-hybrid-effectiveness-implementation-stepped-wedge-cluster-randomized-controlled-trial
#10
JOURNAL ARTICLE
J Margo Brooks Carthon, Heather Brom, Marsha Grantham-Murrillo, Kathy Sliwinski, Aleigha Mason, Mindi Roeser, Donna Miles, Dianne Garcia, Jovan Bennett, Michael O Harhay, Emilia Flores, Kelvin Amenyedor, Rebecca Clark
BACKGROUND: Disparities in posthospitalization outcomes for people with chronic medical conditions and insured by Medicaid are well documented, yet interventions that mitigate them are lacking. Prevailing transitional care interventions narrowly target people aged 65 years and older, with specific disease processes, or limitedly focus on individual-level behavioral change such as self-care or symptom management, thus failing to adequately provide a holistic approach to ensure an optimal posthospital care continuum...
March 26, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38529561/improving-accuracy-of-medication-reconciliation-for-hospitalized-children-a-quality-project
#11
JOURNAL ARTICLE
Samantha M Gunkelman, Jennifer Jamerino-Thrush, Katherine Genet, Martha Blackford, Kerwyn Jones, Michael T Bigham
BACKGROUND AND OBJECTIVES: Medication reconciliation is a complex, but necessary, process to prevent patient harm from medication discrepancies. Locally, the steps of medication reconciliation are completed consistently; however, medication errors still occur, which suggest process inaccuracies. We focused on removal of unnecessary medications as a proxy for accuracy. The primary aim was to increase the percentage of patients admitted to the pediatric hospital medicine service with at least 1 medication removed from the home medication list by 10% during the hospital stay by June of 2022...
March 26, 2024: Hospital Pediatrics
https://read.qxmd.com/read/38528363/determining-breastfeeding-behaviors-during-pregnancy-and-opinions-on-tandem-breastfeeding-among-postpartum-women-in-a-high-fertility-region-of-turkey
#12
JOURNAL ARTICLE
T In, F Koruk
BACKGROUND: Particularly, in regions with high fertility rates, promoting breastfeeding during pregnancy and tandem breastfeeding can be important in increasing breastfeeding rates. OBJECTIVES: This study aimed to understand how postpartum women in a high-fertility region in Turkey approach breastfeeding behaviors during pregnancy and opinions on tandem breastfeeding. MATERIALS AND METHODS: We conducted a descriptive study involving 267 postpartum women hospitalized in a public hospital's postpartum clinic in Sanliurfa, Turkey...
March 1, 2024: Nigerian Journal of Clinical Practice
https://read.qxmd.com/read/38528283/lifestyle-changes-after-cancer-treatment-in-patients-and-their-partners-a-qualitative-study
#13
JOURNAL ARTICLE
Marrit Annika Tuinman, Janine Nuver, Anke de Boer, Anne Looijmans, Mariët Hagedoorn
PURPOSE: Oncologists nowadays promote healthy lifestyle choices more often, focusing on diet, physical activity, smoking, alcohol consumption, and sleep, but the question is whether this is enough to establish actual change. As patients will have to achieve a healthy lifestyle at home in daily life, it is important to understand barriers and facilitators for lifestyle change for both patients and their partners. METHODS: A qualitative interview study was done among patients who received chemotherapy for testicular (n = 10) or breast cancer (n = 7) and their partners (n = 17)...
March 26, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38527733/patient-perceived-understanding-of-home-going-medication-with-transitions-of-care-services-at-a-pediatric-institution
#14
JOURNAL ARTICLE
Karielle Shaffery, Sonya Sebastian, Hannah Thornton, Mahmoud Abdel-Rasoul
BACKGROUND: Transitions of care (TOC) is the coordination and continuity of healthcare as a patient transfers between different settings.1 This can include a wide range of services, such as medication reconciliation, patient counseling, bedside delivery of medications, and others that meet individual patient needs.2 In the pediatric population, patients are at increased risk of potential medication errors and subsequent harm due to reduced patient and/or caregiver health literacy, limited dosage form availability, and errors in medication administration...
March 23, 2024: Journal of the American Pharmacists Association: JAPhA
https://read.qxmd.com/read/38527076/parenteral-nutrition-at-home-long-term-parenteral-nutrition
#15
JOURNAL ARTICLE
Vanessa J Kumpf, Brenda Gray, Jessica Monczka, Sarah Zeraschi, Stanislaw Klek
DISCLAIMER: In an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. PURPOSE: Some diseases require that patients receive parenteral nutrition (PN) over a prolonged time period...
March 25, 2024: American Journal of Health-system Pharmacy: AJHP
https://read.qxmd.com/read/38525784/the-frailty-reduction-via-implementation-of-exercise-nutrition-and-deprescribing-friend-trial-study-protocol-and-recruitment-results
#16
JOURNAL ARTICLE
Michael Inskip, Carolina Almendrales Rangel, Chidiamara Maria Njoku, Fiona Barnett, Isabel Shih, Leonie O'Neill, Maria A Fiatarone Singh, Trinidad Valenzuela
INTRODUCTION: Virtually all adults in aged care facilities are frail, a condition which contributes to falls, cognitive decline, hospitalisation, and mortality. Polypharmacy, malnutrition, sedentariness, and sarcopenia are risk factors amenable to intervention. The Asia-Pacific Frailty Management Guidelines recommend anabolic exercise and the optimisation of medications and nutrition. However, no study has evaluated this best practice intervention triad in aged care. METHODS: The Frailty Reduction via the Implementation of Exercise, Nutrition, and Deprescribing (FRIEND) Trial (ANZCTR No...
March 22, 2024: Methods and Protocols
https://read.qxmd.com/read/38525628/the-use-of-emergency-medical-services-for-palliative-situations-in-western-cape-province-south-africa-a-retrospective-descriptive-analysis-of-patient-records
#17
JOURNAL ARTICLE
C Gage, B Spies, K Crombie, L Gwyther, W Stassen
BACKGROUND: An estimated 56.8 million people require palliative care annually, while only 14% receive such care. This imbalance is particularly acute in low-to middle-income countries (LMICs), where up to 80% of patients requiring palliative care reside. To correct this imbalance, integration between palliative services and other disciplines has been recommended. While improved palliative care integration is a priority in the South African (SA) LMIC context, emergency medical services (EMS) and palliative care remain non-integrated...
November 6, 2023: South African Medical Journal
https://read.qxmd.com/read/38525412/advances-in-human-centered-care-to-address-contemporary-unmet-needs-in-chronic-dialysis
#18
REVIEW
Sumedh Jayanti, Gopala K Rangan
Advances in the treatment of kidney failure with chronic dialysis have stagnated over the past three decades, with over 50% of patients still managed by conventional in-hospital haemodialysis. In parallel, the demands of chronic dialysis medical care have changed and evolved due to a growing population that has higher frailty and multimorbidity. Thus, the gap between the needs of kidney failure patients and the healthcare capability to provide effective overall management has widened. To address this problem, healthcare policy has increasingly aligned towards a human-centred approach...
2024: International Journal of Nephrology and Renovascular Disease
https://read.qxmd.com/read/38523960/variation-in-access-to-palliative-radiotherapy-in-prostate-cancer-a-population-based-study-in-canada
#19
JOURNAL ARTICLE
Alborz Jooya, Daniel Qureshi, William J Phillips, Jennifer Leigh, Colleen Webber, Ajay Aggarwal, Peter Tanuseputro, Scott Morgan, Robert Macrae, Michael Ong, Jean-Marc Bourque
BACKGROUND: As a result of improvements in cancer therapies, patients with metastatic malignancies are living longer, and the role of palliative radiotherapy has become increasingly recognized. However, access to adequate palliative radiotherapy may continue to be a challenge, as is evident from the high proportion of patients dying of prostate cancer who never receive palliative radiotherapy. The main objective of this investigation is to identify and describe the factors associated with the receipt of palliative radiation treatment in a decedent cohort of prostate cancer patients in Ontario...
February 2024: Curēus
https://read.qxmd.com/read/38523896/a-rare-case-of-acute-methotrexate-toxicity-leading-to-bone-marrow-suppression
#20
Samreen Khuwaja, Matthew Lyons, Beenish Zulfiqar
Methotrexate is a first-line disease modifying antirheumatic drug used for the treatment of inflammatory arthritis. Bone marrow suppression is a common adverse reaction of methotrexate following its long-term use. However, low dose methotrexate is rarely associated with life-threatening bone marrow suppression. This case represents an atypical presentation of acute bone marrow suppression shortly after initiating treatment with low-dose methotrexate. A 76-year-old male patient presented with oral ulcers, poor oral intake, and acute kidney injury within 3 weeks of initiating 15 mg weekly of methotrexate for seronegative rheumatoid arthritis...
2024: Case Reports in Rheumatology
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