keyword
https://read.qxmd.com/read/38542497/disruption-of-neuromuscular-junction-following-spinal-cord-injury-and-motor-neuron-diseases
#21
REVIEW
Colin Nemeth, Naren L Banik, Azizul Haque
The neuromuscular junction (NMJ) is a crucial structure that connects the cholinergic motor neurons to the muscle fibers and allows for muscle contraction and movement. Despite the interruption of the supraspinal pathways that occurs in spinal cord injury (SCI), the NMJ, innervated by motor neurons below the injury site, has been found to remain intact. This highlights the importance of studying the NMJ in rodent models of various nervous system disorders, such as amyotrophic lateral sclerosis (ALS), Charcot-Marie-Tooth disease (CMT), spinal muscular atrophy (SMA), and spinal and bulbar muscular atrophy (SBMA)...
March 20, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38542013/difference-in-buccal-gingival-thickness-between-the-mandible-and-maxilla-in-the-aesthetic-zone-a-systematic-review-and-meta-analysis
#22
REVIEW
Linda Schwarz, Oleh Andrukhov, Marco Aoqi Rausch, Xiaohui Rausch-Fan, Erwin Jonke
Background: Fragile gingival tissue is a risk factor for the development of gingival recessions. Despite the fact that gingival recessions are more commonly seen around anterior mandibular teeth, previous research has predominantly concentrated on the gingival dimensions in the anterior maxilla. The objective was to systematically compare buccal gingival thicknesses between the upper and lower jaws in individuals with healthy gingival conditions in the aesthetic zone. Methods: A comprehensive search of three databases was carried out until October 2023...
March 20, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541866/development-and-validation-of-the-scan-score-to-indicate-general-anesthesia-for-dental-care-in-children
#23
JOURNAL ARTICLE
Pierre-Jean Berat, Romain Jacq, Chloé Villain, Sibylle Vital, Alice Germa
Background : General anesthesia is an approach used to address behavior issues in pediatric dentistry. This indication often relies on the practitioner's discretion rather than objective criteria. We developed SCAN-score to assist pediatric dentists in the case of doubt to indicate general anesthesia for uncooperative children. The study aims were to assess the validity of the SCAN-score, which aims to indicate general anesthesia or chairside management for dental care. Methods : A retrospective study was performed on children aged between 2 and 10 years who received dental care...
March 13, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541833/improved-oral-health-is-associated-with-a-lower-risk-of-late-onset-ankylosing-spondylitis-a-nationwide-cohort-study
#24
JOURNAL ARTICLE
Min Kyung Chung, Yoonkyung Chang, Jung-Hyun Park, Gwang Hyun Leem, Tae-Jin Song
Background : The aim of this study was to evaluate the association of oral health status and habits with the occurrence of ankylosing spondylitis (AS) in a nationwide population-based cohort in a longitudinal setting. Methods: A total of 2,415,963 individuals aged 40-79 years who underwent oral health examinations were included from the National Health Insurance Service-National Health Screening (NHIS-HEALS) cohort of Korea between 2003 and 2004. The occurrence of AS was analyzed according to the oral health status and oral hygiene habits...
March 11, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38541692/expression-of-inflammatory-mediators-in-biofilm-samples-and-clinical-association-in-multiple-sclerosis-patients-in-remission-a-pilot-study
#25
JOURNAL ARTICLE
Jakob Fehlhofer, Jutta Ries, Florian Tobias Nickel, Veit Rothhammer, Stefan Schwab, Marco Kesting, Mayte Buchbender
Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of unknown etiology that affects the central nervous system and can lead to neurological impairment. Our aim was to determine whether MS patients also show inflammatory changes in the oral cavity more frequently than healthy individuals. For this purpose, we examined plaque samples for various mediators and their correlation with clinical findings. A study group (MS) and a control group were examined and compared. The plaque samples were analyzed for the expression of interleukins (IL-2, -6, -10), matrix metalloproteinases (MMP-7, MMP-9), and a surface antigen CD90 by quantitative real-time PCR...
March 11, 2024: Life
https://read.qxmd.com/read/38541567/preload-and-removal-torque-of-two-different-prosthetic-screw-coatings-a-laboratory-study
#26
JOURNAL ARTICLE
Lara Coelho, José Manuel Mendes, Joana Mendes, Carlos Aroso, António Sérgio Silva, Maria-Cristina Manzanares-Céspedes
This study aimed to evaluate the effect of two coating materials, a silicone sealing gel and a polytetrafluoroethylene (PTFE) tape, on the screw preload and removal torque value (RTV) to develop strategies to prevent prosthetic screw loosening. We examined 45 complexes comprising an implant, abutment, and prosthetic screw, of which 15 samples were uncoated, 15 were coated with GapSeal® (Hager & Werken GmbH & Co., Duisburg, Germany), and 15 were coated with PTFE tape (MIARCO® , Valencia, Spain)...
March 20, 2024: Materials
https://read.qxmd.com/read/38541514/conformation-effect-on-the-mechanical-and-microbiological-behavior-of-invisible-orthodontic-aligners
#27
JOURNAL ARTICLE
Juan Carlos Rodríguez Fernández, Francisco Pastor, José María Barrera Mora, Elena Demiquels, Eduardo Espinar, Javier Gil
Invisible orthodontic aligners are having a great impact on tooth movement in an aesthetic and effective way. Different techniques, models, and clinical aspects have been studied for their proper use. However, the aim of this research has been to determine the effect of the shaping process on mechanical properties and their bacterial behavior. For this study, 40 original polyurethane plates and 40 identical models, obtained by hot forming the original plates, were used. The static tensile mechanical properties were studied with a Zwick testing machine using testing speeds of 5 mm/min at a temperature of 37 °C...
March 16, 2024: Materials
https://read.qxmd.com/read/38541251/charting-the-future-of-oral-health-a-bibliometric-exploration-of-quality-of-life-research-in-dentistry
#28
JOURNAL ARTICLE
Agatha Ravi Vidiasratri, Lisdrianto Hanindriyo, Caroline Manuela Hartanto
In recent decades, the focus of health research has shifted to the impact of disease or impairment on how people proceed, behave, and experience quality of life. People's lives are affected by oral diseases in various ways. Oral health-related quality of life (OHRQoL) is inextricably linked to general health and well-being, and it has far-reaching consequences for clinical practice and dentistry research. Particularly in Indonesia, increasing attention to OHRQoL is related to several concerning oral conditions, such as the extremely high number of cases of tooth decay and inflammation of dental supportive tissue that inexplicably lowers the population's OHRQoL...
February 22, 2024: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/38541250/estimation-of-oral-disease-burden-among-older-adults-in-ltc-a-scoping-review
#29
REVIEW
Bathsheba Turton, Gheed Alqunaybit, Amrita Tembhe, Alaa Qari, Kadambari Rawal, Ernest Mandel, Joseph Calabrese, Michelle Henshaw
Oral health is an essential part of healthy aging and very little data exists around the disease burden for older adults in a long-term care setting. The aim of this scoping review was to estimate the disease burden of dental caries, periodontal disease, and tooth loss among older adults in Long-Term Care (LTC). This scoping review was conducted in accordance with the Joanna Briggs Institute methodology. A detailed strategy was used to conduct a comprehensive search of electronic databases: PubMed, Embase, and Dentistry and Oral Sciences Source (DOSS)...
February 21, 2024: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/38541227/fully-characterized-effective-bacteriophages-specific-against-antibiotic-resistant-enterococcus-faecalis-the-causative-agent-of-dental-abscess
#30
JOURNAL ARTICLE
Asmaa Ramadan, Mohamed O Abdel-Monem, Noha K El-Dougdoug, Alsayed E Mekky, Shymaa A Elaskary, Abdulaziz A Al-Askar, Shimaa A Metwally, Ahmed F El-Sayed, Gehad AbdElgayed, Ebrahim Saied, Mohamed Khedr
Background and Objectives : Enterococcus faecalis (E. faecalis) is a primary pathogen responsible for dental abscesses, which cause inflammation and pain when trapped between the crown and soft tissues of an erupted tooth. Therefore, this study aims to use specific phages as an alternative method instead of classical treatments based on antibiotics to destroy multidrug-resistant E. faecalis bacteria for treating dental issues. Materials and Methods : In the current study, twenty-five bacterial isolates were obtained from infected dental specimens; only five had the ability to grow on bile esculin agar, and among these five, only two were described to be extensive multidrug-resistant isolates...
March 19, 2024: Medicina
https://read.qxmd.com/read/38541199/new-perspectives-in-third-molar-auto-transplantation-literature-review-and-a-case-report-of-clinical-financial-and-forensic-implications
#31
REVIEW
Alessandra Putrino, Enrico Marinelli, Alessandro Agrillo, Simona Zaami
Third molar extraction is the most common procedure in oral and maxillofacial surgery. Third molars are considered less functional than other teeth and are often extracted. Sometimes, they are also used for auto-transplantation for the benefit of oral rehabilitation. Since many biological factors are involved in this surgical approach, herein, we outline a review of the biological characteristics of medico-legal/forensic interest, in addition to presenting a successful clinical case. A scoping review of currently available research data (following the principles of PRISMA-ScR or the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) on third molar auto-transplantation was conducted by drawing upon the main databases (Scopus, PubMed, Google Scholar and LILACS) to evaluate biological and clinical characteristics possibly relatable to forensic issues...
March 13, 2024: Medicina
https://read.qxmd.com/read/38541163/laser-therapy-effects-on-periodontal-status-a-randomized-study-using-gaussian-network-analysis-and-structural-equation-modeling-approach
#32
JOURNAL ARTICLE
Codruta Elena Ciurescu, Lorena Dima, Vlad Alexandru Ciurescu, Gratiela Georgiana Noja, Alin Viorel Istodor, Marius Alexandru Moga, Lavinia Cosmina Ardelean, Laura-Cristina Rusu, Marius Traian Leretter
Background and Objectives: This paper aims to assess the role of laser therapy in periodontitis through an innovative approach involving computational prediction and advanced modeling performed through network analysis (Gaussian graphical models-GGMs) and structural equations (SEM). Materials and Methods: Forty patients, exhibiting periodontal pockets with a minimum depth of 5 mm, were randomly divided into two groups: a control group and a laser group. Four specific indicators were measured for each tooth, namely periodontal pocket depth (PPD), clinical attachment level (CAL), bleeding on probing (BOP), and plaque index (PI), and the mean of six measured values was recorded at five time markers (baseline, 6 months, 1 year, 2 years, and 4 years)...
March 6, 2024: Medicina
https://read.qxmd.com/read/38541149/infraocclusion-in-the-primary-and-permanent-dentition-a-narrative-review
#33
REVIEW
Paulina Adamska, Hanna Sobczak-Zagalska, Marcin Stasiak, Łukasz Jan Adamski, Dorota Pylińska-Dąbrowska, Sandra Barkowska, Adam Zedler, Michał Studniarek
The gradual movement of a tooth away from the occlusal plane is called infraocclusion or reinclusion. Reincluded teeth are most often deciduous molars, and permanent teeth are less frequently affected. Depending on the level of the infraocclusion, the severity of the disorder is classified as mild, moderate, or severe. The etiology of the phenomenon is not fully known. Tooth submerging can lead to serious complications, such as abnormal position of adjacent teeth, displacement of the bud of the permanent successor, shortening of the dental arch, or developmental disturbances of alveolar process...
March 1, 2024: Medicina
https://read.qxmd.com/read/38541122/the-effect-of-gravity-on-marginal-integrity-of-different-flowable-bulk-fill-resin-composites
#34
JOURNAL ARTICLE
İsmail Hakkı Baltacıoğlu, Gülbike Demirel, Mehmet Eray Kolsuz, Kaan Orhan
Background and Objectives : The aim of this quantitative research was to investigate the effect of gravitational forces on the marginal integrity of different bulk-fill composites by micro-CT imaging. Materials and Methods : Fifty caries-free human third molars extracted for prophylactic purposes were used in this study. Each tooth was prepared with two proximal box cavities, with dimensions of 3 mm × 3 mm × 5 mm. Five distinct groups, each comprising 20 cavities, thus totaling 100 cavities for this study: (1, Group CON): Clearfil Majesty Flow + Clearfil Majesty Esthetic (as the control); (2, Group FBR): Filtek Bulk-fill Flowable Restorative + Clearfil Majesty Esthetic; (3, Group XTB): Voco Extrabase + Clearfil Majesty Esthetic; (4, Group SDR): SDR + Clearfil Majesty Esthetic; and (5, Group SNC): Sonicfill...
February 26, 2024: Medicina
https://read.qxmd.com/read/38540720/micro-osteoperforations-accelerate-tooth-movement-without-exacerbating-the-progression-of-root-resorption-in-rats
#35
JOURNAL ARTICLE
Tadasu Sugimori, Masaru Yamaguchi, Jun Kikuta, Mami Shimizu, Shinichi Negishi
A recent study reported that micro-osteoperforations (MOPs) accelerated tooth movement by activating alveolar bone remodeling. However, very little is known about the relationship between MOPs and external apical root resorption during orthodontic treatment. In this study, in order to investigate the mechanism through which MOPs accelerate tooth movement without exacerbating the progression of root resorption, we measured the volume of the resorbed root, and performed the terminal deoxynucleotidyl transferase (TdT)-mediated dUTP-biotin nick-end labeling (TUNEL) method on exposed MOPs during experimental tooth movements in rats...
March 2, 2024: Biomolecules
https://read.qxmd.com/read/38540307/developing-bioactive-hydrogels-with-peptides-for-dental-application
#36
JOURNAL ARTICLE
Alexandrina Muntean, Codruta Sarosi, Ioan Petean, Stanca Cuc, Rahela Carpa, Ioana Andreea Chis, Aranka Ilea, Ada Gabriela Delean, Marioara Moldovan
Dental caries is an avoidable and complex condition impacting billions of individuals worldwide, posing a specific concern among younger generations, despite the progress of oral hygiene products. This deterioration occurs due to the acid demineralization of tooth enamel, leading to the loss of minerals from the enamel subsurface. The remineralisation of early enamel carious lesions could prevent the cavitation of teeth. The enamel protein amelogenin constitutes 90% of the total enamel matrix protein and plays a key role in the bio mineralisation process...
March 21, 2024: Biomedicines
https://read.qxmd.com/read/38540122/ribonucleic-acid-sequencing-reveals-the-upregulation-and-resolution-of-inflammation-and-extracellular-matrix-remodeling-in-lidocaine-treated-human-acute-monocytic-leukemia-cell-line-thp-1
#37
JOURNAL ARTICLE
Sheng-Wei Feng, Wei-Chun Lin, I-Ta Lee, Sheng-Dean Luo, Ching-Shuen Wang
Lidocaine, a local anesthetic widely used in dentistry, is esteemed for its efficacy and safety. Recent research reveals its additional role in modulating the immune system, and particularly in reducing inflammation crucial for protecting tooth-supporting tissues. Notably, monocytes and macrophages, essential cellular components overseeing various physiological and pathological processes, stand as potential mediators of lidocaine's effects. Therefore, this study aimed to investigate how lidocaine influences cell behavior using RNA sequencing...
February 23, 2024: Biomedicines
https://read.qxmd.com/read/38539994/training-the-concept-of-innovate-in-dolphins-tursiops-truncatus-is-both-creative-and-cognitively-stimulating
#38
JOURNAL ARTICLE
Deirdre B Yeater, Kathleen M Dudzinski, Dawn Melzer, Andrew R Magee, Michaela Robinett, Gonzalo Guerra, Kimberly Salazar, Teri Bolton, Heather Manitzas Hill
Creative or novel behaviors in bottlenose dolphins ( Tursiops truncatus ) can be indicators of flexible thinking and problem solving. Over 50 years ago, two rough-tooth dolphins demonstrated creative novel behaviors acquired through reinforcement training in human care. Since this novel training, a variety of species have been trained to respond to this conceptual cue. The current study assessed the creativity of 12 bottlenose dolphins (5 females, 7 males) housed at the Roatan Institute for Marine Sciences (RIMS) in Roatan, Honduras...
March 14, 2024: Animals: An Open Access Journal From MDPI
https://read.qxmd.com/read/38539459/impact-of-bisphosphonate-therapy-on-oral-health-in-patients-with-breast-and-prostate-cancer-and-bone-metastases-a-comprehensive-study
#39
JOURNAL ARTICLE
Jacek Calik, Katarzyna Calik, Natalia Sauer, Bogucki Zdzisław, Piotr Giedziun, Jacek Mackiewicz, Marek Murawski, Piotr Dzięgiel
This study investigates the impact of bisphosphonate therapy on the stomatognathic system in 80 patients with cancer of the breast and prostate with bone metastases. Bisphosphonates are integral for managing skeletal complications in these malignancies but are associated with bisphosphonate-related osteonecrosis of the jaw (BRONJ), affecting 0.8-18.5% of patients. BRONJ manifests with pain, neuropathy, tissue swelling, mucosal ulceration, tooth mobility, and abscesses, yet its pathogenesis remains elusive, complicating risk prediction...
March 11, 2024: Cancers
https://read.qxmd.com/read/38539393/complication-of-orthodontic-treatment-a-case-report-on-severe-apical-root-resorption-arr-in-a-patient-with-turner-syndrome
#40
Joanna Laskowska, Anna Paradowska-Stolarz, Lucía Miralles-Jordá, Dorota Schutty, Marcin Mikulewicz
External apical root resorption in permanent teeth is a multifactorial process influenced by a variety of local and systemic factors. This report describes a case of multiple and severe apical root resorptions in a patient with Turner syndrome. The condition was discovered in a young female with Turner syndrome after 30 months of orthodontic treatment with fixed appliance. The purpose of this report is to present reports by other authors on the potential causes of the increased risk of tooth resorption in patients with Turner syndrome and to share insights derived from its course, highlighting the implications and lessons learned...
March 18, 2024: Children
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