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https://www.readbyqxmd.com/read/28538371/comparison-of-the-efficacy-and-safety-of-2-lidocaine-hcl-with-different-epinephrine-concentration-for-local-anesthesia-in-participants-undergoing-surgical-extraction-of-impacted-mandibular-third-molars-a-multicenter-randomized-double-blind-crossover-phase-iv
#1
Myong-Hwan Karm, Fiona Daye Park, Moonkyu Kang, Hyun Jeong Kim, Jeong Wan Kang, Seungoh Kim, Yong-Deok Kim, Cheul-Hong Kim, Kwang-Suk Seo, Kyung-Hwan Kwon, Chul-Hwan Kim, Jung-Woo Lee, Sung-Woon Hong, Mi Hyoung Lim, Seung Kwan Nam, Jae Min Cho
BACKGROUND: The most commonly impacted tooth is the third molar. An impacted third molar can ultimately cause acute pain, infection, tumors, cysts, caries, periodontal disease, and loss of adjacent teeth. Local anesthesia is employed for removing the third molar. This study aimed to evaluate the efficacy and safety of 2% lidocaine with 1:80,000 or 1:200,000 epinephrine for surgical extraction of bilateral impacted mandibular third molars. METHODS: Sixty-five healthy participants underwent surgical extraction of bilateral impacted mandibular third molars in 2 separate visits while under local anesthesia with 2% lidocaine with different epinephrine concentration (1:80,000 or 1:200,000) in a double-blind, randomized, crossover trial...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28534987/high%C3%A2-throughput-sequencing-analyses-of-oral-microbial-diversity-in-healthy-people-and-patients-with-dental-caries-and-periodontal-disease
#2
Tingtao Chen, Yan Shi, Xiaolei Wang, Xin Wang, Fanjing Meng, Shaoguo Yang, Jian Yang, Hongbo Xin
Recurrence of oral diseases caused by antibiotics has brought about an urgent requirement to explore the oral microbial diversity in the human oral cavity. In the present study, the high‑throughput sequencing method was adopted to compare the microbial diversity of healthy people and oral patients and sequence analysis was performed by UPARSE software package. The Venn results indicated that a mean of 315 operational taxonomic units (OTUs) was obtained, and 73, 64, 53, 19 and 18 common OTUs belonging to Firmicutes, Bacteroidetes, Proteobacteria, Actinobacteria and Fusobacteria, respectively, were identified in healthy people...
May 17, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28534090/tooth-loss-and-liver-cancer-incidence-in-a-finnish-cohort
#3
Baiyu Yang, Jessica L Petrick, Christian C Abnet, Barry I Graubard, Gwen Murphy, Stephanie J Weinstein, Satu Männistö, Demetrius Albanes, Katherine A McGlynn
PURPOSE: Periodontal disease, a major cause of tooth loss in adults, may have systemic effects and has been associated with higher risk of several cancer types. However, the associations of periodontal disease or tooth loss with liver cancer have only been examined prospectively in two studies, neither of which had sufficient statistical power. In addition, no studies assessed the potential confounding by viral hepatitis or Helicobacter pylori infection status. METHODS: In this study, we examined the association between tooth loss and primary liver cancer incidence in a prospective cohort of Finnish male smokers (n = 29,096)...
May 22, 2017: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/28533013/errors-associated-with-digital-preview-of-computer-engineered-complete-dentures-and-guidelines-for-reducing-them-a-technique-article
#4
Abdulaziz AlHelal, Brian J Goodacre, Mathew T Kattadiyil, Rajesh Swamidass
Patient reports, clinical studies, and systematic reviews reveal a rapid increase in interest in computer-engineered complete dentures (CECDs). The advantages of CECDs include a reduced number of visits, improved fit and retention, and electronic archiving. However, patient dissatisfaction has been reported with CECDs, which may be due to the lack of a trial placement appointment. This technique article identifies errors that occur when CECDs are previewed digitally and proposes guidelines and a checklist to reduce complications such as inadequate esthetics, poor tooth arrangement, misaligned occlusal plane, and inappropriate denture base characteristics...
May 20, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28532609/risk-factors-for-osteonecrosis-of-the-jaw-in-oral-cancer-patients-after-surgery-and-eventual-adjuvant-treatment-the-potential-role-of-chemotherapy
#5
Tzu-Yu Lai, Ti-Hao Wang, Chia-Jen Liu, Tze-Fan Chao, Tzeng-Ji Chen, Yu-Wen Hu
BACKGROUND AND PURPOSE: To identify the risk factors for osteonecrosis of the jaw (ONJ) in oral cancer patients after surgery with and without adjuvant therapy in a nationwide, population-based study. MATERIAL AND METHODS: Using the Taiwan National Health Insurance Research Dataset, we recruited patients with newly diagnosed oral cancer between 1997 and 2011. All of them underwent primary surgery. Data regarding demographic characteristics; tooth extractions; medications; and cancer treatments, including types of mandibular surgery, radiotherapy and platinum-based chemotherapy, were collected for analysis...
May 19, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28532521/animal-board-invited-review-sheep-birth-distribution-in-past-herds-a-review-for-prehistoric-europe-6th-to-3rd-millennia-bc
#6
M Balasse, A Tresset, A Bălăşescu, E Blaise, C Tornero, H Gandois, D Fiorillo, É Á Nyerges, D Frémondeau, E Banffy, M Ivanova
In temperate latitudes sheep have a seasonal reproductive behaviour, which imposes strong constraints on husbandry in terms of work organization and availability of animal products. During the last 50 years, researchers have focused on understanding the mechanisms driving small ruminants' reproduction cycles and finding ways to control them. This characteristic is inherited from their wild ancestor. However, the history of its evolution over the 10 millennia that separates present day European sheep from their Near Eastern ancestors' remains to be written...
May 23, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28532413/dietary-habits-oral-impact-on-daily-performance-and-type-2-diabetes-a-matched-case-control-study-from-sudan
#7
Hasaan G Mohamed, Kamal Mustafa, Salah O Ibrahim, Anne N Åstrøm
BACKGROUND: It is evident that social and behavioural factors influence on individuals' general health and quality of life. Nevertheless, information about the influence of dietary habits on oral health-related quality of life is limited; especially among patients with type 2 diabetes (T2D). The aim of this study was to examine the influence of dietary habits and clinical oral health indicators on oral health-related quality of life in individuals with and without T2D. METHODS: A total of 149 T2D cases and 298 controls were recruited for this age and gender matched case-control study...
May 22, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28531913/methods-of-isolation-and-characterization-of-stem-cells-from-different-regions-of-oral-cavity-using-markers-a-systematic-review
#8
REVIEW
Kavarthapu Avinash, Sankari Malaippan, Jayakumar Nadathur Dooraiswamy
Background: Periodontitis is a destructive inflammatory disorder of the periodontium caused by the destruction of periodontal tissues namely the PDL, cementum, alveolar bone, and gingiva. Once these tissues are lost, the foremost goal of periodontal therapy is to regenerate the diseased tissues if possible to their original form, architecture, and function. Various regenerative procedures were employed and still a gap was found in achieving the goal. As stem cells are characterized by their ability to self-renew and differentiate to produce specialized cells, there could be a possibility of using them for regenerative therapy...
May 30, 2017: International Journal of Stem Cells
https://www.readbyqxmd.com/read/28531377/following-surgically-assisted-rapid-palatal-expansion-do-tooth-borne-or-bone-borne-appliances-provide-more-skeletal-expansion-and-dental-expansion
#9
Adrien Hamedi-Sangsari, Zahra Chinipardaz, Lee Carrasco
PURPOSE: The aim of this study was to compare outcome measurements of skeletal and dental expansion with bone-borne (BB) versus tooth-borne (TB) appliances after surgically assisted rapid palatal expansion (SARPE). This study was performed to provide quantitative measurements that will help the oral surgeon and orthodontist in selecting the appliance with, on average, the greatest amount of skeletal expansion and the least amount of dental expansion. MATERIALS AND METHODS: A computerized database search was performed using PubMed, EBSCO, Cochrane, Scopus, Web of Science, and Google Scholar on publications in reputable oral surgery and orthodontic journals...
April 25, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28531341/intra-observer-reliability-and-agreement-of-manual-and-digital-orthodontic-model-analysis
#10
Vasiliki Koretsi, Linda Tingelhoff, Peter Proff, Christian Kirschneck
Background and aim: Digital orthodontic model analysis is gaining acceptance in orthodontics, but its reliability is dependent on the digitalisation hardware and software used. We thus investigated intra-observer reliability and agreement / conformity of a particular digital model analysis work-flow in relation to traditional manual plaster model analysis. Materials and methods: Forty-eight plaster casts of the upper/lower dentition were collected. Virtual models were obtained with orthoX®scan (Dentaurum) and analysed with ivoris®analyze3D (Computer konkret)...
May 22, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/28531329/alternative-stable-conformation-capable-of-protein-misinteraction-links-trna-synthetase-to-peripheral-neuropathy
#11
David Blocquel, Sheng Li, Na Wei, Herwin Daub, Mathew Sajish, Maria-Luise Erfurth, Grace Kooi, Jiadong Zhou, Ge Bai, Paul Schimmel, Albena Jordanova, Xiang-Lei Yang
While having multiple aminoacyl-tRNA synthetases implicated in Charcot-Marie-Tooth (CMT) disease suggests a common mechanism, a defect in enzymatic activity is not shared among the CMT-causing mutants. Protein misfolding is a common hypothesis underlying the development of many neurological diseases. Its process usually involves an initial reduction in protein stability and then the subsequent oligomerization and aggregation. Here, we study the structural effect of three CMT-causing mutations in tyrosyl-tRNA synthetase (TyrRS or YARS)...
May 22, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28531204/messinian-age-and-savannah-environment-of-the-possible-hominin-graecopithecus-from-europe
#12
Madelaine Böhme, Nikolai Spassov, Martin Ebner, Denis Geraads, Latinka Hristova, Uwe Kirscher, Sabine Kötter, Ulf Linnemann, Jérôme Prieto, Socrates Roussiakis, George Theodorou, Gregor Uhlig, Michael Winklhofer
Dating fossil hominids and reconstructing their environments is critically important for understanding human evolution. Here we date the potentially oldest hominin, Graecopithecus freybergi from Europe and constrain the environmental conditions under which it thrived. For the Graecopithecus-bearing Pikermi Formation of Attica/Greece, a saline aeolian dust deposit of North African (Sahara) provenance, we obtain an age of 7.37-7.11 Ma, which is coeval with a dramatic cooling in the Mediterranean region at the Tortonian-Messinian transition...
2017: PloS One
https://www.readbyqxmd.com/read/28530472/telomerase-expression-in-medaka-oryzias-melastigma-pharyngeal-teeth
#13
W H Tan, P E Witten, C Winkler, D W T Au, A Huysseune
Nonmammalian vertebrates have the capacity of lifelong tooth replacement. In all vertebrates, tooth formation requires contact and interaction between the oral or pharyngeal epithelium and the underlying mesenchyme. To secure lifelong replacement, the presence of odontogenic stem cells has been postulated, particularly in the epithelial compartment. This study uses an advanced teleost fish species, the marine medaka Oryzias melastigma, a close relative to Oryzias latipes, to examine the expression and distribution of telomerase reverse transcriptase (Tert), the catalytic unit of telomerase, in developing pharyngeal teeth and to relate these data to the proliferative activity of the cells...
June 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28530468/genetic-susceptibility-contributing-to-periodontal-and-cardiovascular-disease
#14
G Aarabi, T Zeller, H Seedorf, D R Reissmann, G Heydecke, A S Schaefer, U Seedorf
Periodontal disease (PD) and coronary artery disease (CAD) are common diseases characterized by an overaggressive inflammatory response to diverse stimuli. Whereas PD leads to destruction of the tooth-supporting structures, CAD is a chronic inflammatory condition ultimately causing myocardial infarction via narrowing and occluding of blood vessels. Classical twin studies led to the conclusion that both complex diseases have a similar degree of heritability and that a significant fraction of the genetic factors accounting for this heritability is shared...
June 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28530322/-oro-dento-facial-manifestations-in-patients-with-familial-dysautonomia
#15
REVIEW
Eliyahu Mass
The oro-dento-facial features and dysfunctions of children with hereditary sensory and autonomic neuropathy type III (HSAN III), known as familial dysautonomia (FD) or Riley-Day syndrome, were first described in the scientific literature in 1949. They include: dental trauma, dental and soft tissue selfmutilation, normal dental age, normal sequence and timing of eruption and exfoliation of teeth, smaller tooth size, different and disproportional tooth components, normal alveolar bone height, small jaws, mild crowding and malocclusion...
August 2016: Harefuah
https://www.readbyqxmd.com/read/28529996/multiplexed-sub-doppler-spectroscopy-with-an-optical-frequency-comb
#16
D A Long, A J Fleisher, D F Plusquellic, J T Hodges
An optical frequency comb generated with an electro-optic phase modulator and a chirped radiofrequency waveform is used to perform pump-probe spectroscopy on the D1 and D2 transitions of atomic potassium at 770.1 nm and 766.7 nm, respectively. With a comb tooth spacing of 200 kHz and an optical bandwidth of 2 GHz the hyperfine transitions can be simultaneously observed. Interferograms are recorded in as little as 5 μs (a timescale corresponding to the inverse of the comb tooth spacing). Importantly, the sub-Doppler features can be measured as long as the laser carrier frequency lies within the Doppler profile, thus removing the need for slow scanning or a priori knowledge of the frequencies of the sub-Doppler features...
December 2016: Physical Review. A
https://www.readbyqxmd.com/read/28529977/judgment-of-the-quality-of-restorative-care-as-predictors-of-restoration-retreatment-findings-from-the-national-dental-pbrn
#17
J L Riley, G H Gilbert, G W Ford, J L Fellows, B Rindal, V V Gordan
The primary aim of this study was to test the hypothesis that a patient's subjective assessments of the dentist's technical competence, quality of care, and anticipated restoration longevity during a restorative visit are predictive of restoration outcome. This prospective cohort study involved 3,326 patients who received treatment for a defective restoration in a permanent tooth, participated in a baseline patient satisfaction survey, and returned for follow-up. Of the 4,400 restorations that were examined by 150 dentists, 266 (6%) received additional treatment after baseline...
April 2017: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28529280/alternative-methods-to-visual-and-radiographic-examinations-for-approximal-caries-detection
#18
Naif Abogazalah, Masatoshi Ando
A shift in caries prevalence from occlusal surfaces to approximal surfaces has been demonstrated by epidemiological studies. Two recent meta-analyses evaluated the performance of visual examination and radiography for carious lesion detection, and reported low sensitivity but high specificity for early approximal caries detection. This suggests that the conventional methods have a higher risk of failing to detect approximal lesions. Consequently, in caries susceptible populations, there is a risk of progression of non-cavitated lesions to irreversible tooth destruction before the lesions are detected...
May 19, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28529279/comparing-the-occlusal-contact-area-of-individual-teeth-during-low-level-clenching
#19
Hideta Nishimori, Takashi Iida, Hirona Kamiyama, Yoshihiro Komoda, Ryoko Obara, Takashi Uchida, Misao Kawara, Osamu Komiyama
The aim of this study was to investigate the occlusal contact area (OCA) in individual teeth during low-level tooth clenching in 24 healthy participants. Before measurements were made, the 100% maximum voluntary contraction (MVC) was determined. At baseline, all subjects were instructed to close their mouth and touch the opposing teeth with minimal force. Occlusal contact was recorded during three jaw motor tasks (baseline, 20% MVC, and 40% MVC) using a blue silicone material. OCA thickness was determined from images and defined on five levels: level 1 (0-149 µm), level 2 (0-89 µm), level 3 (0-49 µm), level 4 (0-29 µm), and level 5 (0-4 µm)...
May 19, 2017: Journal of Oral Science
https://www.readbyqxmd.com/read/28529175/longevity-of-2-and-3-surface-restorations-in-posterior-teeth-of-25-to-30-year-olds-attending-public-dental-service-a-13-year-observation
#20
Ulla Palotie, Anna K Eronen, Kimmo Vehkalahti, Miira M Vehkalahti
OBJECTIVES: The aim of this patient document-based retrospective study among 25- to 30-year-old Finnish adults was to evaluate longevity of 2- and 3-surface posterior restorations according to type of tooth, size of restoration, and restorative material used. METHODS: Data were extracted from electronic patient files of the Helsinki City Public Dental Service (PDS), Finland. A total of 5542 2- and 3-surface posterior composite and amalgam restorations were followed indirectly from 2002 to 2015...
May 18, 2017: Journal of Dentistry
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