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https://www.readbyqxmd.com/read/28335583/is-accessibility-to-dental-care-facilities-in-rural-areas-associated-with-number-of-teeth-in-elderly-residents
#1
Tsuyoshi Hamano, Miwako Takeda, Kazumichi Tominaga, Kristina Sundquist, Toru Nabika
Given that public transportation networks are less developed in rural than in urban areas, a lack of accessibility to dental care facilities could be a barrier to routine dental checkups. Thus, we hypothesized that the distance to the dental care facilities is a risk factor for tooth loss. The aim of this study was to test whether there is an association between the distance to dental care facilities, estimated by geographic information systems, and number of teeth, assessed by an oral examination, among elderly residents of a rural area in Japan...
March 21, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28335037/lrsam1-mediated-ubiquitylation-is-disrupted-in-axonal-charcot-marie-tooth-disease-2p
#2
Johanna E Hakonen, Vincenzo Sorrentino, Rossella Avagliano Trezza, Marit B de Wissel, Marlene van den Berg, Boris Bleijlevens, Fred van Ruissen, Ben Distel, Frank Baas, Noam Zelcer, Marian A J Weterman
Charcot-Marie-Tooth (CMT) disease type 2 is a genetically heterogeneous group of inherited neuropathies characterized by motor and sensory deficits as a result of peripheral axonal degeneration. We recently reported a frameshift mutation in the RING domain of LRSAM1 (c.2121_2122dup, p.Leu708Argfs) that encodes an E3 ubiquitin ligase, as the cause of axonal type CMT (CMT2P). However, the frequency of LRSAM1 mutations in CMT2 and the functional basis for their association with disease remains unknown. In this study we evaluated LRSAM1 mutations in two large Dutch cohorts...
March 15, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28334782/golgi-retained-cx32-mutants-interfere-with-gene-addition-therapy-for-cmt1x
#3
Styliana Kyriakoudi, Irene Sargiannidou, Alexia Kagiava, Margarita Olympiou, Kleopas A Kleopa
Numerous GJB1 gene mutations cause the X-linked form of Charcot-Marie-Tooth disease (CMT1X). GJB1 encodes connexin32 (Cx32), which forms trans-myelin gap junctions in Schwann cells. Most GJB1 mutations result in loss-of-function mechanisms, supporting the concept of gene replacement therapy. However, interactions between delivered wild type and endogenously expressed mutant Cx32 may potentially occur in the setting of gene replacement therapy. In order to screen for possible interactions of several representative CMT1X mutants with wild type Cx32 that may interfere with functional gap junction formation, we established an in vitro screening method co-expressing in HeLa cells wild type Cx32 and one of eight different Cx32 mutants including A39P, A39V, T55I, R75W, M93V, L143P, N175D and R183S...
February 21, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28334057/esthetic-and-patient-centered-outcomes-of-single-implants-a-retrospective-study
#4
Björn Gjelvold, Bruno Ramos Chrcanovic, Ingrid Collin Bagewitz, Jenö Kisch, Tomas Albrektsson, Ann Wennerberg
PURPOSE: The aims of this clinical study were to retrospectively evaluate implant survival, patient satisfaction, and radiographic, clinical, and esthetic outcomes following single-implant treatment. MATERIALS AND METHODS: Eighty-seven patients, with a total of 126 implants (XiVE S, Dentsply Implants), who received single implant-retained crowns between 2004 and 2011 were retrospectively evaluated. Implant survival, marginal bone levels (MBL), changes in implant/mesial tooth vertical relationship, pink esthetic score (PES), white esthetic score (WES), patient assessment of the esthetics (visual analog scale), and oral health impact profile (OHIP-14) were evaluated...
March 23, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28333394/socket-shield-technique-for-immediate-implant-placement-clinical-radiographic-and-volumetric-data-after-5%C3%A2-years
#5
Daniel Bäumer, Otto Zuhr, Stephan Rebele, Markus Hürzeler
OBJECTIVES: Implant placement immediately after tooth extraction is often accompanied by resorption of surrounding tissues. A clinical technique was developed where the buccal portion of the root is retained to preserve the periodontal ligament and bundle bone. This technique is based on animal studies showing the potential to preserve the facial tissues utilizing this approach. The purpose of this study was to gain more insight regarding the safety of the technique with regard to biological and implant-related long-term complications and to observe the clinical appearance of the peri-implant tissues...
March 23, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28333370/influence-of-nickel-titanium-rotary-systems-with-varying-tapers-on-the-biomechanical-behaviour-of-maxillary-first-premolars-under-occlusal-forces-a-finite-element-analysis-study
#6
S Askerbeyli Ors, A Serper
AIM: To evaluate the effect of three nickel-titanium (Ni-Ti) rotary systems with varying tapers on stress distribution and to analyse potential fracture patterns as well as the volume of fracture-susceptible regions in two-rooted maxillary premolars. METHODOLOGY: The root canals of three single-rooted premolars were prepared with either HeroShaper (Micro-Mega, Besançon, France) to (size 30, .04 taper), Revo-S (Micro-Mega) to AS30 (size 30, .06 taper) or ProTaper Universal (Dentsply Maillefer, Ballaigeus, Switzerland) to F3 (size 30, ...
March 23, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28332866/comparing-cone-beam-computed-tomography-with-periapical-radiography-for-assessing-root-canal-obturation-in-vivo-using-microsurgical-findings-as-validation
#7
Dongzhe Song, Lan Zhang, Wei Zhou, Qinghua Zheng, Xingyu Duan, Xuedong Zhou, Dingming Huang
OBJECTIVES: The aim of this study was to verify whether there is a difference in the in vivo performance characteristics of CBCT and periapical radiography (PR) in assessing the apical extension of root canal obturation (RCO) and to evaluate the ability of CBCT in void detection using microsurgical findings as validation. METHODS: This study included 323 tooth roots that required surgical treatment and for which pre-existing periapical radiographs and CBCT images were available...
March 23, 2017: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/28332813/competitive-adsorption-of-polyelectrolytes-onto-and-into-pellicle-coated-hydroxyapatite-investigated-by-qcm-d-and-force-spectroscopy
#8
Hyun-Su Lee, Carl Myers, Lynette Zaidel, Prathima Chandra Nalam, Matthew Alexander Caporizzo, Carlo Daep, David M Eckmann, James G Masters, Russell J Composto
A current effort in preventive dentistry is to inhibit surface attachment of bacteria using antibacterial polymer coatings on the tooth surface. For the antibacterial coatings, the physisorption of anionic and cationic polymers directly onto hydroxyapatite (HA) and saliva treated HA surfaces was studied using quartz crystal microbalance, force spectroscopy and atomic force microscopy. First, single species adsorption is shown to be stronger on HA surfaces than on silicon oxide surfaces for all polymers (i.e...
March 23, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28332470/adult-onset-demyelinating-neuropathy-associated-with-fbln5-gene-mutation
#9
Si Cheng, He Lv, Wei Zhang, Zhaoxia Wang, Xin Shi, Wei Liang, Yun Yuan
Rare forms of autosomal-dominant Charcot-Marie-Tooth disease (AD-CMT) may be associated with mutations in Fibulin-5 (FBLN5) as AD-CMT is genetically heterogeneous. Here, we report the first pathological study of an Asian family. The proband was a 46-year-old man with slowly progressive distal numbness and weakness for 12 years. He had a history of diabetes mellitus for 12 years. His mother was 81 years old and had mild polyneuropathy. His 16-year-old daughter was asymptomatic. The nerve conduction velocities (NCVs) and compound muscular action potential (CMAP) amplitudes were moderately to severely reduced in the proband, and moderately reduced in his daughter and mother...
March 23, 2017: Clinical Neuropathology
https://www.readbyqxmd.com/read/28332068/photobiomodulation-with-led-and-laser-in-repair-of-mandibular-socket-rabbit-clinical-evaluation-histological-and-histomorphometric
#10
Cláudio Rômulo Comunian, Antônio Luis Neto Custódio, Leandro Junqueira de Oliveira, Carlos Eduardo Assis Dutra, Milton D'almeida Ferreira Neto, Cleuza Maria Faria Rezende
PURPOSE: The aim of this study was to evaluate the effects of LED and low-intensity laser on the healing of rabbit dental alveoli. METHODS: A total of 18 rabbits were divided into three groups of six; all rabbits underwent surgical extraction of the first lower right premolar. Following surgery, group 1 received LED irradiation, group 2 received laser irradiation, and group 3 were untreated controls. The initial applications of LED and laser began 48 h after tooth extraction and were given perpendicularly to the dental alveoli...
March 23, 2017: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28331854/dental-age-and-tooth-development-in-orthodontic-patients-with-agenesis-of-permanent-teeth
#11
Jozo Badrov, Tomislav Lauc, Enita Nakaš, Ivan Galić
Objective. To compare the development of permanent teeth in a group of children with the congenitally missing permanent teeth (CMPT) and corresponding nonaffected group. Methods. The formation stages of all developing permanent teeth were determined on 345 panoramic radiographs (OPTs) by the method of Haavikko (1970), and dental age was calculated. The paired samples t-test was used to compare the differences between dental age (DA) and chronological age (CA) in those with CMPT and those not affected. Spearman test was used to evaluate the correlation between DA-CA and the number of missing teeth...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28331407/designation-of-a-neotype-and-redescription-of-hesione-reticulata-von-marenzeller-1879-from-japan-annelida-hesionidae
#12
Naoto Jimi, Sergio I Salazar-Vallejo, Hiroshi Kajihara
The hesionid polychaete Hesione reticulata von Marenzeller, 1879 was described from Enoshima Island, Japan and has been recorded also from the Red Sea. Depending on researchers, it has been regarded as either a distinct species or synonymous with older established ones. The type specimen has been lost. In order to clarify its taxonomic status, Hesione reticulata is herein redescribed, illustrated, and a neotype is proposed based on recent material collected near the type locality. The diagnostic features include the presence of several dorsal, discontinuous longitudinal bands, interrupted by pale segmental spots; prostomium with tiny antennae; a tuberculated dorsal integument; acicular lobes double; and neurochaetal blades with guards approaching the distal tooth...
2017: ZooKeys
https://www.readbyqxmd.com/read/28331230/dentin-sialoprotein-facilitates-dental-mesenchymal-cell-differentiation-and-dentin-formation
#13
Wentong Li, Lei Chen, Zhuo Chen, Lian Wu, Junsheng Feng, Feng Wang, Lisa Shoff, Xin Li, Kevin J Donly, Mary MacDougall, Shuo Chen
Dentin sialoprotein (DSP) is a dentin extracellular matrix protein. It is involved in dental mesenchymal cell lineages and dentin formation through regulation of its target gene expression. DSP mutations cause dentin genetic diseases. However, mechanisms of DSP in controlling dental mesenchymal cell differentiation are unknown. Using DSP as bait, we screened a protein library from mouse odontoblastic cells and found that DSP is a ligand and binds to cell surface receptor, occludin. Further study identified that the C-terminal DSP domain(aa 363-458) interacts with the occludin extracellular loop 2(aa 194-241)...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28329793/oral-disease-and-3-year-incidence-of-frailty-in-mexican-older-adults
#14
Roberto Carlos Castrejón-Pérez, Aida Jiménez-Corona, Eduardo Bernabé, Antonio R Villa-Romero, Elise Arrivé, Jean-François Dartigues, Luis Miguel Gutiérrez-Robledo, S Aída Borges-Yáñez
Background: Poor oral health has been associated with some components of frailty. The objective of this study was to identify the association between clinical measures of oral health and the incidence of frailty among community-dwelling older adults aged 70 or older in Mexico City. Methods: A 3-year cohort study with a probabilistic representative sample of home-dwelling elders of one district of Mexico City was performed. Baseline and follow-up interview and oral clinical evaluations were carried out by standardized examiners in participants' homes...
October 25, 2016: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28328975/a-new-species-of-argyromys-rodentia-mammalia-from-the-oligocene-of-the-valley-of-lakes-mongolia-its-importance-for-palaeobiogeographical-homogeneity-across-mongolia-china-and-kazakhstan
#15
Paloma López-Guerrero, Olivier Maridet, Zhaoqun Zhang, Gudrun Daxner-Höck
We describe a new species of Rodentia (Mammalia), Argyromys cicigei sp. nov. from Toglorhoi (fossil bed TGW-A/2a) in Mongolia and Ulantatal (fossil beds UTL 1 and UTL 7) in China. Its tooth morphology differs from the type species Argyromys aralensis from Akespe in Kazakhstan by smaller size and simpler structures. Argyromys has been assigned in different families of Muroidea, such as Tachyoryctoididae and Spalacidae. However, the presence of common characters indicates a closer relationship of Argyromys with the genera of Cricetidae s...
2017: PloS One
https://www.readbyqxmd.com/read/28328951/practising-pastoralism-in-an-agricultural-environment-an-isotopic-analysis-of-the-impact-of-the-hunnic-incursions-on-pannonian-populations
#16
Susanne E Hakenbeck, Jane Evans, Hazel Chapman, Erzsébet Fóthi
We conducted a multi-isotope study of five fifth-century AD cemeteries in modern-day Hungary to determine relationships between nomadic-pastoralist incomers-the historically documented Huns and other nomadic groups-and the sedentary agricultural population of the late Roman province of Pannonia. Contemporary historical sources describe this relationship as adversarial and destructive for the late Roman population, but archaeological evidence indicates high levels of hybridity between different groups. We undertook carbon, nitrogen, strontium and oxygen isotope analyses of bone collagen, dentine and tooth enamel at Keszthely-Fenékpuszta, Hács-Béndekpuszta, Győr-Széchenyi Square, Mözs and Szolnok-Szanda to examine these relationships through past subsistence practices...
2017: PloS One
https://www.readbyqxmd.com/read/28328799/oral-microbiome-in-hiv-associated-periodontitis
#17
Marc Noguera-Julian, Yolanda Guillén, Jessica Peterson, David Reznik, Erica V Harris, Sandeep J Joseph, Javier Rivera, Sunil Kannanganat, Rama Amara, Minh Ly Nguyen, Simon Mutembo, Roger Paredes, Timothy D Read, Vincent C Marconi
HIV-associated periodontal diseases (PD) could serve as a source of chronic inflammation. Here, we sought to characterize the oral microbial signatures of HIV+ and HIV- individuals at different levels of PD severity.This cross-sectional study included both HIV+ and HIV- patients with varying degrees of PD. Two tooth, 2 cheek, and 1 saliva samples were obtained for microbiome analysis. Mothur/SILVADB were used to classify sequences. R/Bioconductor (Vegan, PhyloSeq, and DESeq2) was employed to assess overall microbiome structure differences and differential abundance of bacterial genera between groups...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28328601/improving-the-results-of-cross-lip-vermilion-flap-in-cleft-patients
#18
Amin Rahpeyma, Saeedeh Khajehahmadi
Cross lip vermilion flap is a myomucosal flap that uses lower red lip to augment deficient upper lip vermilion. Technical note that helps in imitating upper lip tubercle structure is presented. Appropriate patient selection to prevent unfavorable results such as color mismatch, local vermilion excess, and lower lip thinning are presented. Indirect benefits of this flap for decreasing upper incisor tooth show and better balance of upper/lower lip thickness are discussed.
March 21, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28327693/single-versus-two-visits-with-1-week-intracanal-calcium-hydroxide-medication-for-endodontic-treatment-one-year-post-treatment-results-from-a-multicentre-randomised-controlled-trial
#19
Federica Fonzar, Aniello Mollo, Mauro Venturi, Pierpaolo Pini, Riccardo Fabian Fonzar, Anna Trullenque-Eriksson, Marco Esposito
PURPOSE: To evaluate whether it is more effective to complete endodontic treatment in a single visit or in two visits with 1-week intracanal calcium hydroxide medication in symptomatic teeth and teeth with periapical lesions. MATERIALS AND METHODS: One hundred and ninety-nine patients, with one symptomatic tooth or a tooth with a periapical lesion, were randomised, according to a parallel group design, to receive a complete endodontic treatment in a single visit (99 patients) or in two visits with 1-week intracanal calcium hydroxide medication (100 patients), at two centres...
2017: European Journal of Oral Implantology
https://www.readbyqxmd.com/read/28327692/immediate-immediate-delayed-6%C3%A2-weeks-and-delayed-4%C3%A2-months-post-extractive-single-implants-1-year-post-loading-data-from-a-randomised-controlled-trial
#20
Marco Esposito, Giovanni Zucchelli, Gioacchino Cannizzaro, Luigi Checchi, Carlo Barausse, Anna Trullenque-Eriksson, Pietro Felice
PURPOSE: To compare the clinical outcome of single implants placed immediately after tooth extraction with implants placed 6 weeks after tooth extraction (immediate-delayed placement), and with implants placed after 4-month extraction and socket healing (delayed placement). MATERIALS AND METHODS: Two-hundred and ten (210) patients requiring a single implant-supported crown to replace a tooth to be extracted were randomised to receive immediate post-extractive implants (70 patients), immediate-delayed implants at 6 weeks (70 patients), and delayed implants after 4 months of healing (70 patients) according to a parallel group design...
2017: European Journal of Oral Implantology
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