keyword
MENU ▼
Read by QxMD icon Read
search

Pediatric Tuberculosis

keyword
https://www.readbyqxmd.com/read/28731663/-pulmonary-actinomycosis-and-tuberculosis-a-comorbidity-pediatric-case
#1
Elsa D Bisero, Graciela F Luque, Cristina N Rizzo, Alejandra E Zapata, María S Cuello
Actinomycosis is a chronic suppurative infection, produced by anaerobic Gram-positive bacteria or microaerobic Actinomyces species. It is rare in children and adolescents and it is more common in immunocompromised. Mycobacterium tuberculosis collaborates on the development of the disease. Pulmonary involvement appears as a picture of chronic condensation that does not improve with conventional antibiotic treatment. Classic complications affecting the thoracic wallwith drainage in «sulfur granule» and fistulization are described less frequently nowadays...
August 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28729186/-tuberculosis-treatment-for-children-an-update
#2
María José Mellado Peña, Begoña Santiago García, Fernando Baquero-Artigao, David Moreno Pérez, Roi Piñeiro Pérez, Ana Méndez Echevarría, José Tomás Ramos Amador, David Gómez-Pastrana Durán, Antoni Noguera Julian
Tuberculosis (TB) is the most important infectious disease all over the world, with a high morbidity and mortality. Pediatric tuberculosis has been a neglected epidemic, due to the difficulties in assessing its global impact, reduced incidence and lower infectivity compared to adults. In 2015, the WHO reported 1 million cases of paediatric TB and 169,000 deaths. In Europe, the emergence of MDR TB is a major concern, representing 16% of the new diagnosis in Eastern Europe. In 2014, it was estimated that about 219,000 children were infected by MDR-TB-strains in Europe, and 2,120 developed the disease...
July 17, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28724962/novel-transcriptional-signatures-for-sputum-independent-diagnostics-of-tuberculosis-in-children
#3
John Espen Gjøen, Synne Jenum, Dhanasekaran Sivakumaran, Aparna Mukherjee, Ragini Macaden, Sushil K Kabra, Rakesh Lodha, Tom H M Ottenhoff, Marielle C Haks, Timothy Mark Doherty, Christian Ritz, Harleen M S Grewal
Pediatric tuberculosis (TB) is challenging to diagnose, confirmed by growth of Mycobacterium tuberculosis at best in 40% of cases. The WHO has assigned high priority to the development of non-sputum diagnostic tools. We therefore sought to identify transcriptional signatures in whole blood of Indian children, capable of discriminating intra-thoracic TB disease from other symptomatic illnesses. We investigated the expression of 198 genes in a training set, comprising 47 TB cases (19 definite/28 probable) and 36 asymptomatic household controls, and identified a 7- and a 10-transcript signature, both including NOD2, GBP5, IFITM1/3, KIF1B and TNIP1...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28691431/low-dose-computed-tomography-in-assessment-of-pulmonary-abnormalities-in-children-with-febrile-neutropenia-suffering-from-malignant-diseases
#4
REVIEW
Urszula Zaleska-Dorobisz, Cyprian Michal Olchowy, Mateusz Łasecki, Dąbrówka Sokołowska-Dąbek, Aleksander Pawluś, Jowita Frączkiewicz, Ewa Gorczyńska
BACKGROUND: Management of febrile neutropenia in pediatric patients is challenging. Chest X-ray and CT help to identify infective foci; however, exposure to radiation is a risk factor for development of secondary cancer. For this reason, attention is paid to reduce radiation exposure. OBJECTIVES: TTo define the role of LDCT examination in early detection of pulmonary lesions in children during oncology or autoimmune treatment complicated by neutropenia related fever...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28687246/edwin-lawrence-kendig-jr-md-dsc-hon-1911-2003
#5
REVIEW
Barry V Kirkpatrick
Edwin Kendig, MD is considered one of the founders of pediatric pulmonology. Prompted by his own experience with tuberculosis, he opened a 'chest clinic' for children, where he worked for 50years. He systematically published his observations and was the original editor of the first textbook in pediatric pulmonology in 1967. His book, now called Kendig and Chernick's Disorders of the Respiratory Tract in Children will publish its 9th edition in 2018. All of this was in addition to his primary care pediatric practice, his teaching and his work at the national and international level of pediatric care...
June 11, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28651293/-tuberculosis-guideline-for-adults-guideline-for-diagnosis-and-treatment-of-tuberculosis-including-ltbi-testing-and-treatment-of-the-german-central-committee-dzk-and-the-german-respiratory-society-dgp
#6
Tom Schaberg, Torsten Bauer, Folke Brinkmann, Roland Diel, Cornelia Feiterna-Sperling, Walter Haas, Pia Hartmann, Barbara Hauer, Jan Heyckendorf, Christoph Lange, Albert Nienhaus, Ralf Otto-Knapp, Martin Priwitzer, Elvira Richter, Rudolf Rumetshofer, Karl Schenkel, Otto Dagobert Schoch, Nicolas Schönfeld, Ralf Stahlmann
Since 2015 a significant increase in tuberculosis cases is notified in Germany, mostly due to rising numbers of migrants connected to the recent refugee crisis. Because of the low incidence in previous years, knowledge on tuberculosis is more and more limited to specialized centers. However, lung specialist and healthcare workers of other fields have contact to an increasing number of tuberculosis patients. In this situation, guidance for the management of standard therapy and especially for uncommon situations will be essential...
June 2017: Pneumologie
https://www.readbyqxmd.com/read/28633501/epidemiology-of-pediatric-multidrug-resistant-tuberculosis-in-the-united-states-1993-2014
#7
Sarah E Smith, Robert Pratt, Lisa Trieu, Pennan M Barry, Dzung T Thai, Shama Desai Ahuja, Sarita Shah
Background: Multidrug-resistant tuberculosis (MDR TB) is an important global public health threat, but accurate estimates of MDR TB burden among children are lacking. Methods: We analyzed demographic, clinical and laboratory data for newly-diagnosed pediatric (<15 years) TB cases reported to the US National TB Surveillance System (NTSS) during 1993-2014. MDR TB was defined as culture-confirmed TB disease with resistance to at least isoniazid and rifampicin. To ascertain potential under-estimation of pediatric MDR TB, we surveyed high burden states for clinically-diagnosed cases treated for MDR TB...
June 19, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28626255/underlying-cause-of-death-recorded-during-2013-to-2015-at-a-tertiary-general-hospital-in-vientiane-capital-lao-pdr
#8
Bounfeng Phoummalaysith, Viengsakhone Louangpradith, Tavanh Manivon, Bounxou Keohavong, Eiko Yamamoto, Nobuyuki Hamajima
In Lao People's Democratic Republic (Lao PDR), the cause of death is not registered in death reports. As a result, the government cannot produce official reports that show mortality according to cause of death. This study aimed to report the underlying cause of death in a tertiary general hospital (Mittaphab Hospital) in Vientiane capital. Mittaphab hospital is a governmental teaching hospital with 300 beds for inpatient services specialized in orthopedics, neurology, and hemodialysis. Since a children hospital exists beside Mittaphab Hospital, severe pediatric cases are referred to the child hospital...
February 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/28605426/biomarkers-of-cerebral-injury-and-inflammation-in-pediatric-tuberculous-meningitis
#9
Ursula K Rohlwink, Katya Mauff, Katalin A Wilkinson, Nico Enslin, Emmanuel Wegoye, Robert J Wilkinson, Anthony A Figaji
Background: Tuberculous meningitis (TBM) leads to death or disability in half the affected individuals. Tools to assess severity and predict outcome are lacking. Neuro-specific biomarkers could serve as markers of the severity and evolution of brain injury, but have not been widely explored in TBM. We examined biomarkers of neurological injury (neuromarkers) and inflammation in pediatric TBM and their association with outcome. Methods: Blood and cerebrospinal fluid (CSF) of children with TBM and hydrocephalus taken on admission and over 3 weeks were analysed for neuromarkers S100B, neuron-specific enolase (NSE) and glial fibrillary acidic protein (GFAP), and multiple inflammatory markers...
June 9, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28598771/barriers-to-initiating-tuberculosis-treatment-in-sub-saharan-africa-a-systematic-review-focused-on-children-and-youth
#10
Brittney J Sullivan, B Emily Esmaili, Coleen K Cunningham
BACKGROUND: Tuberculosis (TB) is the deadliest infectious disease globally, with 10.4 million people infected and more than 1.8 million deaths in 2015. TB is a preventable, treatable, and curable disease, yet there are numerous barriers to initiating treatment. These barriers to treatment are exacerbated in low-resource settings and may be compounded by factors related to childhood. OBJECTIVE: Timely initiation of tuberculosis (TB) treatment is critical to reducing disease transmission and improving patient outcomes...
2017: Global Health Action
https://www.readbyqxmd.com/read/28559702/tubercular-abdominal-cocoon-in-children-a-single-centre-study-in-remote-area-of-northern-india
#11
Rikki Singal, B Satyashree, Amit Mittal, Bhanu Pratap Sharma, Samita Singal, Muzzafarr Zaman, Parteek Shardha
BACKGROUND: Amongst the numerous causes of intestinal obstruction listed in the literature, sclerosing encapsulating peritonitis also called Abdominal Cocoon (AC) is one of the rarest entities. Its characteristic feature is a thick fibrotic membrane encasing varying lengths of the small and large gut in a cocoon. In India, there is an increasing incidence of tuberculosis, especially in the rural areas. AIMS AND OBJECTIVES: The aim of this study was to investigate the clinical presentation and evaluate the operative findings of tuberculous AC...
2017: Clujul Medical (1957)
https://www.readbyqxmd.com/read/28559513/extrapulmonary-tuberculosis-in-colombian-children-epidemiological-and-clinical-data-in-a-reference-hospital
#12
Eileen Viviana Fonseca Sepulveda, Luisa Fernanda Imbachí Yunda, Kelly Christina Márquez Herrera, German Camacho Moreno
BACKGROUND: The pediatric population is at increased risk of disseminated and extrapulmonary tuberculosis (TB). There is little information on children affected by this entity. The demographic, clinical, and outcome characteristics of the treatment of children with extrapulmonary TB, treated at a national reference institution between January 1, 2008, and December 31, 2016, are described and analyzed in this work. MATERIALS AND METHODS: This was a retrospective observational study...
April 2017: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28540624/need-for-different-cutoff-values-for-reading-mantoux-test-with-2tu-and-5tu-ppd
#13
Savitha M Ramaraj, K Nagendra, Girish Gopal, Sumanth Mallikarjuna Majgi
OBJECTIVE: To compare the tuberculin reaction of 2 tuberculin unit (TU) with 5TU purified protein derivative (PPD) (both calibrated against RT 23) in healthy children. METHODS: This was a cross sectional study done in the pediatric outpatient department of a tertiary care teaching hospital. Seventy healthy siblings of the children attending pediatric outpatient department in the age group of 1 to 12 y were enrolled. The exclusion criteria included previously diagnosed tuberculosis patients, malnutrition diagnosed according to the WHO classification, history of drug intake like steroids, recent history of measles, any skin lesions over forearm, history of fever, contact with tuberculosis and previous mantoux testing...
May 25, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28528339/molecular-diagnosis-of-tubercular-lymphadenopathy-from-fine-needle-aspirates-in-pediatric-patients
#14
Vivek Gupta, Arvind Bhake
OBJECTIVES: The diagnosis of peripheral tubercular lymphadenopathy (TBLN) in pediatric patients is often a challenge because features evident on fine-needle aspiration cytology (FNAC) or tissue biopsy can be deceptive for the reason that they result from an immunological response. This study aimed to evaluate polymerase chain reaction (PCR) for Mycobacterium tuberculosis complex (MTBC) in pediatric patients under clinical suspicion for TBLN and to assess its role in the evaluation of cases cytodiagnosed as reactive lymphoid hyperplasia...
2017: Acta Cytologica
https://www.readbyqxmd.com/read/28512556/pediatric-tuberculosis-in-northern-sardinia
#15
Maria Grazia Clemente, Elena Dore, Lidia Abis, Paola Molicotti, Stefania Zanetti, Paolina Olmeo, Roberto Antonucci
BACKGROUND AND OBJECTIVES: Migration flux is an increasing phenomenon in Italy, and it raises several public health issues and concerns in pediatric infectious diseases. This study investigated the clinical characteristics and outcomes of a pediatric population at high-risk for tuberculosis (TB) and the potential role of immigration as a risk factor. DESIGN: We performed an observational retrospective study of children referred to the only Pediatric Infectious Diseases Unit for Northern Sardinia over a 6-year-period (2009-2014)...
2017: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/28510461/underlying-causes-of-persistent-and-recurrent-pneumonia-in-children-at-a-pulmonary-referral-hospital-in-tehran-iran
#16
Mohammad Reza Bolursaz, Ferial Lotfian, Hossein Ali Ghaffaripour, Maryam Hassanzad
BACKGROUND: There is limited data on recurrent or persistent pneumonia in children, particularly in the developing world. This is a retrospective, cross-sectional study of children with recurrent or persistent pneumonia admitted to the Pediatric Department of Massih Daneshvari Hospital, Tehran, Iran. METHODS: Children under 18 years of age, who were admitted to the hospital with pneumonia between 2007 and 2013, were investigated to find out the prevalence of recurrent and persistent pneumonia and to recognize their underlying diseases...
May 2017: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/28505015/virologic-response-to-first-line-efavirenz-or-nevirapine-based-antiretroviral-therapy-in-hiv-infected-african-children
#17
Adeodata Kekitiinwa, Alexander J Szubert, Moira Spyer, Richard Katuramu, Victor Musiime, Tawanda Mhute, Sabrina Bakeera-Kitaka, Oscar Senfuma, Ann Sarah Walker, Diana M Gibb
BACKGROUND: Poorer virologic response to nevirapine- versus efavirenz-based antiretroviral therapy (ART) has been reported in adult systematic reviews and pediatric studies. METHODS: We compared drug discontinuation and viral load (VL) response in ART-naïve Ugandan/Zimbabwean children ≥3 years of age initiating ART with clinician-chosen nevirapine versus efavirenz in the ARROW trial. Predictors of suppression <80, <400 and <1000 copies/mL at 36, 48 and 144 weeks were identified using multivariable logistic regression with backwards elimination (P = 0...
June 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28502224/diagnosis-and-treatment-of-paediatric-tuberculosis-an-insight-review
#18
Nityananda Mandal, Parveen Kumar Anand, Subhash Gautam, Shritam Das, Tahziba Hussain
Tuberculosis (TB) is a major public health problem, invading all age groups world-wide. It is an opportunistic infection affecting the individuals alone or with co-infections. Childhood TB is a neglected aspect and a significant health problem in epidemic areas. It constitutes more than 20% of TB incidence. Pediatric TB exists in the shadow of adult TB. The clinicians concentrate on pulmonary manifestation of TB, whereas it is a major problem in both pulmonary and extra-pulmonary infections. The rate of infection with this disease is mostly associated with poverty, social disruption and human immunodeficiency virus (HIV) infection...
August 2017: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/28482957/pediatric-and-adolescent-tuberculosis-in-latvia-2011-2014-case-detection-diagnosis-and-treatment
#19
B Ziemele, R Ranka, I Ozere
OBJECTIVE: To perform a comprehensive analysis of case detection, diagnosis and treatment of tuberculosis (TB) in children and adolescents in Latvia, and to evaluate the utility of the current approach. DESIGN: A retrospective study of all Latvian children and adolescents diagnosed with TB from 1 January 2011 to 31 December 2014. RESULTS: Of 3081 patients diagnosed with TB during 2011-2014, 250 (8%) were aged <18 years, and 80% were identified through contact investigation...
June 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28480653/the-rate-of-drug-resistant-tuberculosis-in-korean-children-and-adolescents-since-2007
#20
Hyun Jung Kim, Hyung Ho Yoon, Byung Wook Eun, Youngmin Ahn, Sungweon Ryoo, Hee Jin Kim
The incidence of drug-resistant tuberculosis (DR-TB) in pediatric populations is a critical indicator of national TB management and treatment strategies. Limited data exist regarding the rate of pediatric DR-TB. In this study, we aimed to analyze the status of DR-TB in Korean children from 2007 to 2013. We analyzed specimens submitted to the Korean Institute of Tuberculosis using Mycobacterium tuberculosis culture and drug susceptibility tests (DSTs) from January 2007 through December 2013. Specimens from patients ≤ 19 years of age were included...
June 2017: Journal of Korean Medical Science
keyword
keyword
38985
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"