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https://www.readbyqxmd.com/read/28715309/rise-of-the-nanorobots-advances-in-control-molecular-detection-and-nanoscale-actuation-are-bringing-us-closer-to-a-new-era-of-technology-enhanced-by-nanorobots
#1
Stanislav Tsitkov, Henry Hess
In 1988, a Scientific American article by A.K. Dewdney [1] on the work of nanotechnologist K. Eric Drexler spurred public interest in the nascent field of nanotechnology and its potential for advancing humanity into a new technological age. The article portrayed a world run by nanoscale machines that could operate in any environment (Figure 1), with uses ranging from fighting infections in the human body to building tomorrow's skyscrapers. Nearly 30 years later, these visions of the future are closer than ever...
July 2017: IEEE Pulse
https://www.readbyqxmd.com/read/28714778/how-clients-change-emotion-with-emotion-a-programme-of-research-on-emotional-processing
#2
Antonio Pascual-Leone
This paper reviews a body of research that has examined Pascual-Leone and Greenberg's sequential model of emotional processing or used its accompanying measure (the Classification of Affective Meaning States). Research from 24 studies using a plurality of methods examined process-outcome relationships from micro to macro levels of observation and builds support for emotional transformation as a possible causal mechanism of change in psychotherapy. A pooled sample of 310 clinical and 130 sub-clinical cases have been studied, reflecting the process of 7 different treatment approaches in addressing over 5 different presenting clinical problems (including depression, anxiety, relational trauma, and personality disorders)...
July 17, 2017: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://www.readbyqxmd.com/read/28713851/building-an-experimental-model-of-the-human-body-with-non-physiological-parameters
#3
Joseph M Labuz, Christopher Moraes, David R Mertz, Brendan M Leung, Shuichi Takayama
New advances in engineering and biomedical technology have enabled recent efforts to capture essential aspects of human physiology in microscale, in-vitro systems. The application of these advances to experimentally model complex processes in an integrated platform - commonly called a 'human-on-a-chip (HOC)' - requires that relevant compartments and parameters be sized correctly relative to each other and to the system as a whole. Empirical observation, theoretical treatments of resource distribution systems and natural experiments can all be used to inform rational design of such a system, but technical and fundamental challenges (e...
March 2017: Technology
https://www.readbyqxmd.com/read/28710141/perspective-improving-nutritional-guidelines-for-sustainable-health-policies-current-status-and-perspectives
#4
Paolo Magni, Dennis M Bier, Sergio Pecorelli, Carlo Agostoni, Arne Astrup, Furio Brighenti, Robert Cook, Emanuela Folco, Luigi Fontana, Robert A Gibson, Ranieri Guerra, Gordon H Guyatt, John Pa Ioannidis, Ann S Jackson, David M Klurfeld, Maria Makrides, Basil Mathioudakis, Alessandro Monaco, Chirag J Patel, Giorgio Racagni, Holger J Schünemann, Raanan Shamir, Niv Zmora, Andrea Peracino
A large body of evidence supports the notion that incorrect or insufficient nutrition contributes to disease development. A pivotal goal is thus to understand what exactly is appropriate and what is inappropriate in food ingestion and the consequent nutritional status and health. The effective application of these concepts requires the translation of scientific information into practical approaches that have a tangible and measurable impact at both individual and population levels. The agenda for the future is expected to support available methodology in nutrition research to personalize guideline recommendations, properly grading the quality of the available evidence, promoting adherence to the well-established evidence hierarchy in nutrition, and enhancing strategies for appropriate vetting and transparent reporting that will solidify the recommendations for health promotion...
July 2017: Advances in Nutrition
https://www.readbyqxmd.com/read/28708302/advancing-oral-health-policy-and-advocacy-to-prevent-childhood-obesity-and-reduce-children-s-consumption-of-sugar-sweetened-beverages
#5
Ankit Sanghavi, Nadia J Siddiqui
PURPOSE: While a large body of work documents the interconnections between oral health and obesity, less is known about the role that oral health professionals and organizations play to prevent childhood obesity, especially by influencing children's consumption of sugar-sweetened beverages (SSBs). This review identifies efforts by oral health professionals and organizations to influence such policy and advocacy, while informing future opportunities to leverage and expand on existing efforts...
July 14, 2017: Journal of Public Health Dentistry
https://www.readbyqxmd.com/read/28708077/environmental-drivers-and-predicted-risk-of-bacillary-dysentery-in-southwest-china
#6
Han Zhang, Yali Si, Xiaofeng Wang, Peng Gong
Bacillary dysentery has long been a considerable health problem in southwest China, however, the quantitative relationship between anthropogenic and physical environmental factors and the disease is not fully understand. It is also not clear where exactly the bacillary dysentery risk is potentially high. Based on the result of hotspot analysis, we generated training samples to build a spatial distribution model. Univariate analyses, autocorrelation and multi-collinearity examinations and stepwise selection were then applied to screen the potential causative factors...
July 14, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28707625/bioprinting-of-functional-vascularized-mouse-thyroid-gland-construct
#7
Elena A Bulanova, Elizaveta V Koudan, Jonathan Degosserie, Charlotte Heymans, Frederico DAS Pereira, Vladislav A Parfenov, Yi Sun, Qi Wang, Suraya A Akhmedova, Irina K Sviridova, Natalia S Sergeeva, Georgy A Frank, Yusef D Khesuani, Christophe E Pierreux, Vladimir A Mironov
Bioprinting can be defined as additive biofabrication of 3D tissues and organ constructs using tissue spheroids, capable of self-assembly, as building blocks. Thyroid gland, a relatively simple endocrine organ, is suitable for testing the proposed bioprinting technology. Here we report the bioprinting of functional vascularized mouse thyroid gland construct from embryonic tissue spheroids as a proof of concept. Based on the self-assembly principle, we generated thyroid tissue starting from thyroid spheroids (TS) and allantoic spheroids (AS), as a source of thyrocytes and endothelial cells (EC), respectively...
July 14, 2017: Biofabrication
https://www.readbyqxmd.com/read/28703288/a-comparative-proteomic-analysis-of-blood-serum-for-developmental-stages-in-pigs
#8
K Srikanth, E Lee, A Kwon, J Shin, H Chung
This study aimed to differentiate genes at developmental stages of pigs from 0 to 150 days of age, to build up a protein database and to find candidate genetic markers for growth traits. The analysis of two-dimensional electrophoresis and matrix-assisted laser-desorption/ionization mass spectrometry separated 252 protein segments. After successfully blasting the peptide sequences, the analysis confirmed 37 differentially expressed proteins that increased from birth to 150 days of age (type A), whereas the type B proteins presented the inverse pattern...
July 12, 2017: Animal Genetics
https://www.readbyqxmd.com/read/28702735/is-the-extrastriate-body-area-part-of-the-dorsal-visuomotor-stream
#9
Marius Zimmermann, Rogier B Mars, Floris P de Lange, Ivan Toni, Lennart Verhagen
The extrastriate body area (EBA) processes visual information about body parts, and it is considered one among a series of category-specific perceptual modules distributed across the occipito-temporal cortex. However, recent evidence raises the possibility that EBA might also provide an interface between perception and action, linking the ventral and dorsal streams of visual information processing. Here, we assess anatomical evidence supporting this possibility. We localise EBA in individual subjects using a perceptual task and compare the characteristics of its functional and structural connectivity to those of two perceptual areas, the lateral occipital complex (LOC) and the fusiform body area (FBA), separately for each hemisphere...
July 12, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28700259/mixed-method-study-to-investigate-models-of-australian-integrative-oncology
#10
EunJin Lim, Janette L Vardy, Byeongsang Oh, Haryana M Dhillon
OBJECTIVES: This study explored the models of services and experiences of coordinators and directors engaged in providing complementary and alternative medicine (CAM) or integrative medicine (IM) in oncology centers throughout Australia. DESIGN: Fourteen leaders of IM programs from ten systematically selected Australian oncology centers were interviewed. Participants described their center's service model. Interview transcripts were thematically analyzed to identify underlying themes...
July 12, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28691876/-physiological-pathophysiological-and-clinical-significance-of-chromogranins-secretogranins
#11
Lajos Jakab
This paper investigates the fundamental knowledge, build-up, as well as essential structural and important features of the big family of chromogranins/secretogranins. Previously the different properties and the slightly diverging funcional relations of the two family members were in focus. Later on, it has been discovered that they are essentially two similar compounds with identical structures and functions, and they are chemically, biochemically related. From details discovered so far we can tell that they are long polypeptid chains formed from amino acids...
July 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28690665/use-of-integrative-medicine-in-the-united-states-military-health-system
#12
REVIEW
Cathaleen Madsen, Megan Vaughan, Tracey Pérez Koehlmoos
Integrative medicine (IM) is a model of care which uses both conventional and nonconventional therapies in a "whole person" approach to achieve optimum mental, physical, emotional, spiritual, and environmental health, and is increasingly popular among patients and providers seeking to relieve chronic or multifactorial conditions. The US Department of Defense (DoD) shows particular interest in and usage of IM for managing chronic conditions including the signature "polytrauma triad" of chronic pain, traumatic brain injury (TBI), and posttraumatic stress disorder (PTSD) among its beneficiaries in the Military Health System (MHS)...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28686013/in-line-shunt-flow-monitor-for-hydrocephalus
#13
Chuchu Qin, Brian N Stamos, Purnendu K Dasgupta
In hydrocephalus cerebrospinal fluid (CSF) builds up in the cranial cavity causing swelling of the head and potentially brain damage. A shunt to drain the fluid into a body cavity is now universally used but failure is all too common. Techniques for ascertaining shunt failure are time-consuming, expertise-dependent and often inconclusive. We report here an in-line system that reliably and quantitatively measures the CSF flow rate. The system uses a single thermistor to both heat the surrounding and to sense the temperature...
July 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28685668/investigating-the-asymmetrical-roles-of-syllabic-and-phonemic-awareness-in-akshara-processing
#14
Pooja R Nakamura, R Malatesha Joshi, Xuejun Ryan Ji
In this study, we examine the relative contributions of syllabic awareness, phonemic awareness, and oral vocabulary knowledge in early akshara reading ability from Grades 1 through 5. The performance of 488 students in two states of South India, Karnataka (Kannada language) and Andhra Pradesh (Telugu language), was measured. Results from a commonality analysis indicate that there was an increasing independent contribution of syllabic awareness to Kannada and Telugu decoding through the five grades, but the unique contribution of phonemic awareness steadily declined through the five grades, as it became subsumed within syllabic awareness...
July 1, 2017: Journal of Learning Disabilities
https://www.readbyqxmd.com/read/28685298/benchmarking-of-human-dose-prediction-for-inhaled-medicines-from-preclinical-in-vivo-data
#15
Therese Ericsson, Markus Fridén, Carina Kärrman-Mårdh, Ian Dainty, Ken Grime
PURPOSE: A scientifically robust prediction of human dose is important in determining whether to progress a candidate drug into clinical development. A particular challenge for inhaled medicines is that unbound drug concentrations at the pharmacological target site cannot be easily measured or predicted. In the absence of such data, alternative empirical methods can be useful. This work is a post hoc analysis based on preclinical in vivo pharmacokinetic/pharmacodynamic (PK/PD) data with the aim to evaluate such approaches and provide guidance on clinically effective dose prediction for inhaled medicines...
July 6, 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28683773/determinants-and-time-to-blood-transfusion-among-thermal-burn-patients-admitted-to-mulago-hospital
#16
C Kilyewala, R Alenyo, R Ssentongo
BACKGROUND: Blood transfusion, a practice under re-evaluation in general, remains common among thermal burn patients due to the hematological alterations associated with burns that manifest as anemia. Today advocacy is for restrictive blood transfusion taking into account individual patient characteristics. We went out to identify the parameters that may determine transfusion requirement and the time to blood transfusion for thermal burn patients in Mulago Hospital in order to build statistics and a basis to standardize future practice and Hospital protocol...
July 6, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28680475/the-geography-of-pre-criminal-space-epidemiological-imaginations-of-radicalisation-risk-in-the-uk-prevent-strategy-2007-2017
#17
Charlotte Heath-Kelly
This paper explores geographical and epistemological shifts in the deployment of the UK Prevent strategy, 2007 - 2017. Counter-radicalisation policies of the Labour governments (2006 - 2010) focused heavily upon resilience-building activities in residential communities. They borrowed from historical models of crime prevention and public health to imagine radicalisation risk as an epidemiological concern in areas showing a 2% or higher demography of Muslims. However, this racialized and localised imagination of pre-criminal space was replaced, after the election of the Conservative-Liberal Democrat coalition in 2010...
2017: Crit Stud Terror
https://www.readbyqxmd.com/read/28676190/barriers-to-addressing-social-determinants-of-health-in-pediatric-nursing-practice-an-integrative-review
#18
REVIEW
Mary M Tallon, Garth E Kendall, Lynn Priddis, Fiona Newall, Jeanine Young
PROBLEM: Despite a substantial body of knowledge regarding the importance of the social determinants of health, recognizing and responding to the psychosocial circumstances of seriously and chronically ill children and their families is not well established in routine pediatric nursing care. ELIGIBILITY CRITERIA: The search process focused on psychological and social determinants and care in the healthcare setting. Searches were limited to research and review publications written in the English language...
July 1, 2017: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/28675464/chemical-composition-antimicrobial-and-insecticidal-activity-against-the-lesser-mealworm-alphitobius-diaperinus-panzer-coleoptera-tenebrionidae-of-origanum-vulgare-l-ssp-hirtum-link-and-artemisia-dracunculus-l-essential-oils
#19
Maria Szczepanik, Maciej Walczak, Beata Zawitowska, Marta Michalska-Sionkowska, Antoni Szumny, Czesław Wawrzeńczyk, Maria Swiontek Brzezinska
BACKGROUND: Essential oils (EOs) from Artemisia dracunculus L. and Origanum vulgare L. ssp. hirtum were obtained and the qualitative and quantitative chemical composition of the extracts was investigated. The insecticidal activity of EOs against the larval stages of Alphitobius diaperinus (Panzer) was studied. Moreover, the antimicrobial activity of these oils against pathogens transmitted by this pest was also investigated. RESULTS: The obtained results indicate the possibility of using Greek oregano EO with a high content of carvacrol as a feed additive in poultry nutrition...
July 4, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28671618/vascular-mechanobiology-towards-control-of-in-situ-regeneration
#20
REVIEW
Eline E van Haaften, Carlijn V C Bouten, Nicholas A Kurniawan
The paradigm of regenerative medicine has recently shifted from in vitro to in situ tissue engineering: implanting a cell-free, biodegradable, off-the-shelf available scaffold and inducing the development of functional tissue by utilizing the regenerative potential of the body itself. This approach offers a prospect of not only alleviating the clinical demand for autologous vessels but also circumventing the current challenges with synthetic grafts. In order to move towards a hypothesis-driven engineering approach, we review three crucial aspects that need to be taken into account when regenerating vessels: (1) the structure-function relation for attaining mechanical homeostasis of vascular tissues, (2) the environmental cues governing cell function, and (3) the available experimental platforms to test instructive scaffolds for in situ tissue engineering...
July 3, 2017: Cells
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