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https://www.readbyqxmd.com/read/27936458/predictors-of-functional-disability-with-focus-on-activities-of-daily-living-a-community-based-follow-up-study-in-older-adults-in-india
#1
Aarti Nagarkar, Yashoda Kashikar
BACKGROUND: Disability in activities of daily living is a growing concern among older populations all over the world. India has one of the rapidly ageing populations and predicted burden of functional disability is higher for Indian older adults as compared to other ageing Asian countries. METHODS: Total 1140 aged 60 years and over participated in a baseline study. 560 of them participated in the prospective cohort study conducted in the city of Pune, India. An interview and functional assessment using a questionnaire and Pune-FAAT tool was carried out in 2013-14...
December 2, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/27936440/stride-variability-measures-derived-from-wrist-and-hip-worn-accelerometers
#2
Jacek K Urbanek, Jaroslaw Harezlak, Nancy W Glynn, Tamara Harris, Ciprian Crainiceanu, Vadim Zipunnikov
Many epidemiological and clinical studies use accelerometry to objectively measure physical activity using the activity counts, vector magnitude, or number of steps. These measures use just a fraction of the information in the raw accelerometry data as they are typically summarized at the minute level. To address this problem, we define and estimate two measures of temporal stride-to-stride gait variability based on raw accelerometry data: Amplitude Deviation (AD) and Phase Deviation (PD). We explore the sensitivity of our approach to on-body placement of the accelerometer by comparing hip, left and right wrist placements...
November 30, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27936422/social-network-types-among-older-korean-adults-associations-with-subjective-health
#3
Sung Yun Sohn, Won-Tak Joo, Woo Jung Kim, Se Joo Kim, Yoosik Youm, Hyeon Chang Kim, Yeong-Ran Park, Eun Lee
With population aging now a global phenomenon, the health of older adults is becoming an increasingly important issue. Because the Korean population is aging at an unprecedented rate, preparing for public health problems associated with old age is particularly salient in this country. As the physical and mental health of older adults is related to their social relationships, investigating the social networks of older adults and their relationship to health status is important for establishing public health policies...
December 1, 2016: Social Science & Medicine
https://www.readbyqxmd.com/read/27936147/absence-of-association-between-behavior-problems-in-childhood-and-hypertension-in-midlife
#4
Sadiq M Saad, Gurch Randhawa, Dong Pang
BACKGROUND: It is known that behavior in childhood is associated with certain physical and mental health problems in midlife. However, there is limited evidence on the role of childhood behavior problems in the development of hypertension in adulthood. The present study aimed to examine whether behavior problems in childhood influenced the risk of hypertension in midlife in the United Kingdom 1958 birth cohort. METHODS: The 1958 British birth cohort comprised 17,638 individuals born in the first week of March 1958 in the United Kingdom...
2016: PloS One
https://www.readbyqxmd.com/read/27936145/diurnal-patterns-of-physical-activity-in-relation-to-activity-induced-energy-expenditure-in-52-to-83-years-old-adults
#5
Giulio Valenti, Alberto G Bonomi, Klaas R Westerterp
BACKGROUND: Ageing is associated with a declining physical activity level (PAL) and changes in the diurnal activity pattern. Changes in the activity pattern might help explaining the age-associated reduction of physical activity. OBJECTIVE: The aims were to investigate diurnal activity patterns within groups of older adults classified by PAL, to investigate diurnal activity patterns within age-groups and to investigate the association between the drop in activity and aerobic fitness...
2016: PloS One
https://www.readbyqxmd.com/read/27936083/effectiveness-and-cost-effectiveness-of-a-cluster-randomized-prenatal-lifestyle-counseling-trial-a-seven-year-follow-up
#6
Päivi Kolu, Jani Raitanen, Jatta Puhkala, Pipsa Tuominen, Pauliina Husu, Riitta Luoto
There is a link between the pregnancy and its long-term influence on health and susceptibility to future chronic disease both in mother and offspring. The objective was to determine whether individual counseling on physical activity and diet and weight gain at five antenatal visits can prevent type 2 diabetes mellitus (T2DM) and overweight or improve glycemic parameters, among all at-risk-mothers and their children. Another objective was to evaluate whether gestational lifestyle intervention was cost-effective as measured with mother's sickness absence and quality-adjusted life years (QALY)...
2016: PloS One
https://www.readbyqxmd.com/read/27936024/estimation-of-physical-activity-energy-expenditure-during-free-living-from-wrist-accelerometry-in-uk-adults
#7
Tom White, Kate Westgate, Nicholas J Wareham, Soren Brage
BACKGROUND: Wrist-worn accelerometers are emerging as the most common instrument for measuring physical activity in large-scale epidemiological studies, though little is known about the relationship between wrist acceleration and physical activity energy expenditure (PAEE). METHODS: 1695 UK adults wore two devices simultaneously for six days; a combined sensor and a wrist accelerometer. The combined sensor measured heart rate and trunk acceleration, which was combined with a treadmill test to yield a signal of individually-calibrated PAEE...
2016: PloS One
https://www.readbyqxmd.com/read/27935988/effects-of-a-community-based-healthy-lifestyle-intervention-program-co-help-among-adults-with-prediabetes-in-a-developing-country-a-quasi-experimental-study
#8
Norliza Ibrahim, Foong Ming Moy, Intan Attikah Nur Awalludin, Zainudin Mohd Ali, Ikram Shah Ismail
BACKGROUND: The prevalence of type 2 diabetes among Malaysian adults has increased by more than two folds over the past two decades. Strategies to collaborate with the existing community partners may become a promising channel for wide-scale dissemination of diabetes prevention in the country. The objectives of this study were to determine the effects of community-based lifestyle interventions delivered to adults with prediabetes and their health-related quality of life as compared to the usual care group...
2016: PloS One
https://www.readbyqxmd.com/read/27935966/the-transcription-factor-nfatc2-regulates-%C3%AE-cell-proliferation-and-genes-associated-with-type-2-diabetes-in-mouse-and-human-islets
#9
Mark P Keller, Pradyut K Paul, Mary E Rabaglia, Donnie S Stapleton, Kathryn L Schueler, Aimee Teo Broman, Shuyun Isabella Ye, Ning Leng, Christopher J Brandon, Elias Chaibub Neto, Christopher L Plaisier, Shane P Simonett, Melkam A Kebede, Gloria M Sheynkman, Mark A Klein, Nitin S Baliga, Lloyd M Smith, Karl W Broman, Brian S Yandell, Christina Kendziorski, Alan D Attie
Human genome-wide association studies (GWAS) have shown that genetic variation at >130 gene loci is associated with type 2 diabetes (T2D). We asked if the expression of the candidate T2D-associated genes within these loci is regulated by a common locus in pancreatic islets. Using an obese F2 mouse intercross segregating for T2D, we show that the expression of ~40% of the T2D-associated genes is linked to a broad region on mouse chromosome (Chr) 2. As all but 9 of these genes are not physically located on Chr 2, linkage to Chr 2 suggests a genomic factor(s) located on Chr 2 regulates their expression in trans...
December 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27935902/objectively-measured-physical-activity-and-sedentary-time-in-young-adults-born-preterm-the-ester-study
#10
Marjaana Tikanmäki, Tuija Tammelin, Nina Kaseva, Marika Sipola-Leppänen, Hanna-Maria Matinolli, Harto Hakonen, Ulf Ekelund, Johan G Eriksson, Marjo-Riitta Järvelin, Marja Vääräsmäki, Eero Kajantie
BackgroundYoung adults born preterm have higher levels of cardiometabolic risk factors and they report less physical activity than their peers born at term. Physical activity provides important cardiometabolic health benefits. We hypothesized that objectively measured physical activity levels are lower and time spent sedentary is higher among preterm-born individuals compared to controls.MethodsWe studied unimpaired participants of the ESTER birth cohort study at age 23.3 years (SD: 1.2): 60 born early preterm (<34 weeks), 108 late preterm (34-36 weeks), and 178 at term (controls)...
December 9, 2016: Pediatric Research
https://www.readbyqxmd.com/read/27935875/-modified-circulating-low-density-lipoproteins-pathogenetic-significance-in-angiology
#11
Ya D Babintseva, V P Karagodin, A N Orekhov
Low-density lipoproteins (LDLs) having various modifications are known to be atherogenic, i. e., possessing ability of inducing atherosclerosis. Circulating modified LDLs (cmLDLs) were found in blood of patients diagnosed with atherosclerosis confirmed angiographically. They appear to contain 2-3-fold less sialic acid as compared to LDLs in blood of apparently healthy people; cmLDLs differ by their physical properties: having higher density, smaller diameter, and greater electronegativity; by chemical properties: the amount of neutral sugars (N-acetyl-galactosamine, N-acetyl-glucosamine, galactose and glucose) in cmLSLs of patients with atherosclerosis is 1,5-2 times lower than in native lipoproteins, the levels of free and etherified cholesterol and triglycerides, monoglycerides and free fatty acids are higher, cmLDLs are oxidized and contain altered apolipoprotein B...
2016: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/27935850/physical-activity-start-at-a-younger-age
#12
Joav Merrick
No abstract text is available yet for this article.
December 9, 2016: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/27935793/co-occurring-risk-factors-in-multiple-sclerosis
#13
Julia M Balto, Ipek Ensari, Elizabeth A Hubbard, Naiman Khan, Jennifer L Barnes, Robert W Motl
OBJECTIVE: We examined individual and co-occurring risk factors as correlates of health outcomes in persons with multiple sclerosis (MS). METHODS: Sixty-nine participants with MS completed measures of nutrition, physical activity levels, comorbidity and neuroperformance. The data were analyzed using t-test analyses in SPSS Statistics 22.0. RESULTS: Total number of comorbidities (z = 2.36, p = .02), cardiovascular disease symptoms (z = 2.63, p = ...
January 2017: American Journal of Health Behavior
https://www.readbyqxmd.com/read/27935792/youth-and-caregiver-physical-activity-and-sedentary-time-hchs-sol-youth
#14
Linda C Gallo, Scott P Roesch, Jessica L McCurley, Carmen R Isasi, Daniela Sotres-Alvarez, Alan M Delamater, Linda Van Horn, Elva M Arredondo, Krista M Perreira, Christina Buelna, Qibin Qi, Denise C Vidot, Mercedes R Carnethon
OBJECTIVES: We examined associations between youth and caregiver moderate/ vigorous physical activity (MVPA) and sedentary (SED) time, using accelerometery, in the Hispanic Community Health Study/Study of Latino Youth (HCHS/ SOL) Youth. METHODS: Participants were 623 caregivers and 877 youth 8-16 years old, enrolled in 2012-2014. Associations of youth and caregiver MVPA time, SED time, and meeting MVPA recommendations ( 150 min/week, adults; 420 min/week, youth) were examined in regression models that controlled for sample weights, design effects, and demographic and health covariates...
January 2017: American Journal of Health Behavior
https://www.readbyqxmd.com/read/27935767/effect-of-physical-activity-and-or-healthy-eating-on-gdm-risk-the-dali-lifestyle-study
#15
David Simmons, Roland Devlieger, André van Assche, Goele Jans, Sander Galjaard, Rosa Corcoy, Juan M Adelantado, Fidelma Dunne, Gernot Desoye, Jürgen Harreiter, Alexandra Kautzky-Willer, Peter Damm, Elisabeth R Mathiesen, Dorte M Jensen, Liselotte Andersen, Annunziata Lapolla, Maria G Dalfrà, Alessandra Bertolotto, Ewa Wender-Ozegowska, Agnieszka Zawiejska, David Hill, Frank J Snoek, Judith Gm Jelsma, Mireille Nm van Poppel
CONTEXT: Lifestyle approaches for preventing gestational diabetes mellitus (GDM) have produced mixed results. OBJECTIVE: The aim of this study was to compare the effectiveness of three lifestyle interventions (Healthy eating (HE), Physical activity (PA) and both HE and PA (HE+PA)) with usual care (UC) in reducing GDM risk. DESIGN: Multicentre Randomised Controlled Trial 2012-2014: The Dali Lifestyle Study Setting: Antenatal clinics across 11 centres in 9 European countries Patients: Consecutive pregnant women <20 weeks gestation with a BMI≥29 kg/m(2) and without GDM by IADPSG criteria (n=436)...
December 9, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27935657/profile-and-reintegration-experience-of-ebola-survivors-in-guinea-a-cross-sectional-study
#16
Alexandre Delamou, Bienvenu Salim Camara, Jean Pe Kolie, Achille Diona Guemou, Nyankoye Yves Haba, Shannon Marquez, Beavogui Abdoul Habib, Therese Delvaux, Johan van Griensven
OBJECTIVE: To describe the experience of Guinean Ebola Virus Disease (EVD) survivors in Guinea, up to ten months after discharge from the Ebola treatment unit. METHODS: Cross-sectional study using a standardized semi-structured questionnaire among survivors from Conakry and Coyah districts in 2015 in Guinea. We used proportions, mean (Standard Deviation) and median (Interquartile range) to summarize the variables. The McNemar Chi square test was used to compare proportions...
December 9, 2016: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/27935563/physical-activity-and-walking-performance-influence-on-quality-of-life-in-ambulatory-children-with-cerebral-palsy-cp
#17
Kilby Mann, Elaine Tsao, Kristie F Bjornson
PURPOSE: To examine the relationship of physical activity (PA) and walking performance to QOL in ambulatory children with CP, as function is not consistently associated with QOL in this population. METHODS: A secondary analysis of a cross-sectional cohort of 128 ambulatory children with CP, ages 2.2-9.9 years and GMFCS levels I-III, was employed. Individual multivariate regression models were developed for physical, psychosocial, and total domains of QOL as measured by the Pediatric Quality of Life Inventory (PedsQL) controlling for physical activity and walking performance, participation level and frequency, topography of CP, walking capacity, age, and satisfaction with participation...
December 2, 2016: Journal of Pediatric Rehabilitation Medicine
https://www.readbyqxmd.com/read/27935322/physical-activity-and-cognition-a-mediating-role-of-efficient-sleep
#18
Kristine A Wilckens, Kirk I Erickson, Mark E Wheeler
OBJECTIVE: Physical activity benefits executive control, but the mechanism through which this benefit occurs is unclear. Sleep is a candidate mechanism given that it improves with exercise and has restorative effects on the prefrontal cortex. The present cross-sectional study examined the mediating role of sleep in the relationship between physical activity and executive control in young and older adults. PARTICIPANTS: Young (n = 59) and older (n = 53) community-dwelling adults ages 21-30 and 55-80...
December 9, 2016: Behavioral Sleep Medicine
https://www.readbyqxmd.com/read/27935188/characteristics-of-physical-prefrailty-among-japanese-healthy-older-adults
#19
Eiji Matsushita, Kiwako Okada, Yui Ito, Shosuke Satake, Nariaki Shiraishi, Takahisa Hirose, Masafumi Kuzuya
AIM: The purpose of the present study was to clarify the characteristics of frailty at an early stage (prefrailty) in a healthy elderly Japanese population. METHODS: The participants were 620 healthy older adults (age range 60-89 years) who were current students or graduates of a community college for older adults in Japan. All participants were evaluated using the Kihon Checklist, a tool developed to screen for frailty in Japan. The participants were categorized by the Fried criteria (lost weight, handgrip strength, walking speed, exhaustion, physical activity) into either a prefrailty (1-2 criteria) or a non-frailty (0 criterion) group...
December 9, 2016: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/27935186/coupling-of-a-voltage-gated-ca-2-channel-homologue-with-a-plasma-membrane-h-atpase-in-yeast
#20
Toshihiko Cho, Aya Ishii-Kato, Yuko Fukata, Yoshitaka Nakayama, Kazuko Iida, Masaki Fukata, Hidetoshi Iida
Yeast has a homologue of mammalian voltage-gated Ca(2+) channels (VGCCs), enabling the efficient uptake of Ca(2+) . It comprises two indispensable subunits, Cch1 and Mid1, equivalent to the mammalian pore-forming α1 and auxiliary α2 /δ subunits, respectively. Unlike the physiological roles of Cch1/Mid1 channels, the regulatory mechanisms of the yeast VGCC homologue remain unclear. Therefore, we screened candidate proteins that interact with Mid1 by an unbiased proteomic approach and identified a plasma membrane H(+) -ATPase, Pma1, as a candidate...
December 9, 2016: Genes to Cells: Devoted to Molecular & Cellular Mechanisms
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