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Paranasal sinus tumors

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https://www.readbyqxmd.com/read/29217425/usp6-gene-rearrangement-differentiate-primary-paranasal-sinus-solid-aneurysmal-bone-cyst-from-other-giant-cell-rich-lesions-report-of-a-rare-case
#1
Hung-Ru Li, Chih-Feng Tai, Hsuan-Ying Huang, Ying-Tai Jin, Yi-Ting Chen, Sheau-Feng Yang
Aneurysmal bone cysts (ABCs) mostly occur in the metaphysis of long bones. Primary paranasal ABCs are extremely rare and most reported cases reveal typical histopathological features including cystic space with fibrous septa and hemorrhage. Solid variant ABCs or solid ABCs lacking cyst formation may be histologically indistinguishable from giant cell reparative granulomas (GCRGs), giant cell tumor of bone (GCTB), and brown tumor. Here we report the case of a 24-year-old female with a paranasal mass diagnosed as USP6-rearranged solid ABC, mimicking GCRG, GCTB and brown tumor...
December 4, 2017: Human Pathology
https://www.readbyqxmd.com/read/29215446/nasal-septal-cavernous-hemangioma
#2
Ahmet Baki
Hemangiomas are benign tumors originating from the skin, mucosa, muscle, gland, and vascular tissue in the bone. Although it is common in the head and neck region, it is rarely seen in the nasal cavity and paranasal sinuses. Histologically capillary, cavernous, and mixed types are present, the most common is cavernous-type hemangioma. Cavernous hemangiomas in the nasal cavity, generally originated from the lateral nasal wall, cause symptoms as nasal obstruction and epistaxis. In the author's patient, cavernous hemangioma was originated from the nasal septum, where rarely seen...
December 6, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29211048/imaging-characteristics-of-malignant-sinonasal-tumors
#3
REVIEW
Masaya Kawaguchi, Hiroki Kato, Hiroyuki Tomita, Keisuke Mizuta, Mitsuhiro Aoki, Akira Hara, Masayuki Matsuo
Malignancies of the nasal cavity and paranasal sinuses account for 1% of all malignancies and 3% of malignancies of the upper aerodigestive tract. In the sinonasal tract, nearly half of all malignancies arise in the nasal cavity, whereas most of the remaining malignancies arise in the maxillary or ethmoid sinus. Squamous cell carcinoma is the most common histological subtype of malignant tumors occurring in this area, followed by other epithelial carcinomas, lymphomas, and malignant soft tissue tumors. Although many of these tumors present with nonspecific symptoms, each tumor exhibits characteristic imaging features...
December 6, 2017: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29204580/etiology-of-sinonasal-inverted-papilloma-a-narrative-review
#4
REVIEW
Ming-Jie Wang, Julia E Noel
Objective: Sinonasal inverted papilloma (IP) is a benign and uncommon tumor of the nasal cavity and paranasal sinuses with a tendency for recurrence and even malignant transformation. Though the morphology and clinical behavior of this lesion has been well described, its etiology remains controversial. Methods: Computerized searches were performed in PubMed, Scopus, and Google scholar through May 2015. In this review, etiologic factors including human papilloma virus (HPV), Epstein-Barr virus (EBV), cell cycle related proteins and angiogenic factors, occupational and environmental exposures, and chronic inflammation, will be discussed...
March 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29184714/clinical-significance-of-thickened-sphenoid-sinus-mucosa-in-rathke-s-cleft-cyst
#5
Hiroshi Takasuna, Taigen Sase, Hidemichi Ito, Hajime Ono, Kotaro Oshio, Yuichiro Tanaka
Background: To determine the clinical significance of thickening of the sphenoid sinus mucosa (TSSM) in Rathke's cleft cyst (RCC). Methods: We retrospectively reviewed patients with pituitary lesions. A total of 99 patients, who underwent surgery of pituitary lesions between 2008 and 2015, were analyzed to evaluate the clinical significance of TSSM using magnetic resonance imaging. The patients with TSSM were evaluated for their characteristics. Results: Of the 99 operations, 15 patients with paranasal sinusitis, direct invasion to the sellar floor, and/or a history of transsphenoidal surgery were excluded...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/29173756/proton-therapy-for-head-and-neck-cancers
#6
REVIEW
Pierre Blanchard, Gary Brandon Gunn, Alexander Lin, Robert L Foote, Nancy Y Lee, Steven J Frank
Because of its sharp lateral penumbra and steep distal fall-off, proton therapy offers dosimetric advantages over photon therapy. In head and neck cancer, proton therapy has been used for decades in the treatment of skull-base tumors. In recent years the use of proton therapy has been extended to numerous other disease sites, including nasopharynx, oropharynx, nasal cavity and paranasal sinuses, periorbital tumors, skin, and salivary gland, or to reirradiation. The aim of this review is to present the physical properties and dosimetric benefit of proton therapy over advanced photon therapy; to summarize the clinical benefit described for each disease site; and to discuss issues of patient selection and cost-effectiveness...
January 2018: Seminars in Radiation Oncology
https://www.readbyqxmd.com/read/29166820/sinonasal-smarcb1-ini1-deficient-carcinoma-with-yolk-sac-tumor-differentiation-report-of-a-case-and-comparison-with-ini1-expression-in-gonadal-germ-cell-tumors
#7
Michal Zamecnik, Jiri Rychnovsky, Jakub Syrovatka
SMARCB1 (INI1) deficient sinonasal carcinoma is a recently recognized entity with wide histomorphologic spectrum. We present a case of this carcinoma that contained, in addition to a "common" morphology, scattered foci of yolk sac tumor differentiation. The tumor occurred in paranasal sinuses in a 44-year-old woman. Immunohistochemically, it was diffusely negative for INI1, whereas an expression of yolk sac tumor markers (α-fetoprotein, glypican-3, CDX2) was limited to the yolk sac tumor component. For comparison with the present case, we performed INI1 immunostaining on a series of 11 gonadal germ cell tumors with yolk sac tumor differentiation...
November 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29137081/sinonasal-undifferentiated-carcinoma-originating-from-inverted-papilloma-a-case-report
#8
Jong Seung Kim, Ki Hwan Hong, Kyu Yun Jang, Jong Hoon Song
RATIONALE: Sinonasal inverted papilloma (IP) is a locally aggressive tumor found in the schneiderian membrane, lining the nasal cavity and paranasal sinuses. PATIENT CONCERNS: We report a case of a 63-year-old woman with undifferentiated carcinoma (UC) arising in an IP in the left maxillary sinus. DIAGNOSES: The preoperative diagnosis was IP of the maxillary sinus. INTERVENTIONS: We performed endoscopic medial maxillectomy to remove the remnant mass in the left maxillary sinus...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29134827/serum-plasma-and-saliva-biomarkers-for-head-and-neck-cancer
#9
Lidia Maria Rebolho Batista Arantes, Ana Carolina de Carvalho, Matias Eliseo Melendez, André Lopes Carvalho
Head and neck squamous cell carcinoma (HNSCC) encompasses tumors arising from several locations (oral and nasal cavities, paranasal sinuses, salivary glands, pharynx, and larynx) and currently stands as the sixth most common cancer worldwide. The most important risk factors identified so far are tobacco and alcohol consumption, and, for a subgroup of HNSCCs, infection with high-risk types of human papillomavirus (HPV). Despite several improvements in the treatment of these tumors in the last decades, overall survival rates have only improved marginally, mainly due to the advanced clinical stage at diagnosis and the high rates of treatment failure associated with this late diagnosis...
November 14, 2017: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/29115519/pten-promotes-apoptosis-of-h2o2%C3%A2-injured-rat-nasal-epithelial-cells-through-pi3k-akt-and-other-pathways
#10
Minghui Jia, Xiaoyun Chen, Jili Liu, Jun Chen
Chronic rhinosinusitis (CRS) is a form of chronic inflammation of the nasal cavity and paranasal sinus with multi‑causal pathogenesis, including oxidative stress. Several lines of evidence have demonstrated that the phosphatase and tensin homolog gene (PTEN) can inhibit the activation of phosphoinositide 3‑kinase (PI3K) to affect phosphorylation of Akt. Importantly, the PI3K/PTEN/Akt signaling pathway is associated with various types of tumors, chronic inflammatory diseases, and autoimmune disease through its regulation of cell growth, apoptosis, proliferation, and metabolism...
October 26, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29114305/frontal-mucocele-mimicking-a-frontal-subcutaneous-tumor
#11
Ellath Valappil Bijith, Shaju Mathew, Krishnaswamy Mahadevan
Mucoceles are chronic, expanding, mucosa lined pathology of the paranasal sinuses. Frontal mucocele usually presents with the visual complaints such as diplopia, diminution of vision, visual field defect, ptosis, orbital swelling, retro-orbital pain, displacement of eye globe, and proptosis. Very rarely, it can be present as a subcutaneous swelling. This article presents a 58-year-old male patient presenting with an asymptomatic periorbital swelling and a painless forehead mass of 3 years duration. There was a partial ptosis, and an elongated, soft, subcutaneous mass over the forehead...
October 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29050753/outcome-of-spray-cryotherapy-plus-functional-endoscopic-sinus-surgery-on-management-of-healing-in-nasal-polyposis
#12
Ahmad Rezaeian
BACKGROUND: Nasal Polyposis is a benign tumor in nasal or paranasal mucosa, which confronts difficulties in management of healing after treatments with surgery. The aim of this study was to evaluate the effects of Spray Cryotherapy (SCT) on management of healing in patients with nasal polyposis who undergone functional endoscopic sinus surgery. METHODS: In this prospective, clinical trial study, we investigated on 40 patients with nasal polyposis that had indication for functional endoscopic sinus surgery...
October 10, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29046472/-surgical-treatment-of-a-giant-olfactory-groove-schwannoma-a-case-report
#13
Takashi Fujii, Naoki Otani, Kazuma Doi, Masataka Miyama, Yohei Otsuka, Takashi Matsumoto, Toru Yoshiura, Satoru Takeuchi, Satoshi Tomura, Arata Tomiyama, Terushige Toyooka, Kojiro Wada, Kentaro Mori
Schwannomas originating from the olfactory nerve are extremely rare because the olfactory nerve does not normally contain Schwann cells. We describe a case of a giant schwannoma of the olfactory groove. A 73-year-old woman presented with anosmia persisting for 10 months. Head computed tomography(CT)for head trauma at another hospital demonstrated a tumor lesion located in the left frontal lobe and paranasal sinus. She had never suffered epilepsy, and past medical history and family history identified no indicators...
October 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/29019028/application-of-a-full-model-based-iterative-reconstruction-mbir-in-80%C3%A2-kvp-ultra-low-dose-paranasal-sinus-ct-imaging-of-pediatric-patients
#14
Jihang Sun, Qifeng Zhang, Xiaomin Duan, Chengyue Zhang, Pengpeng Wang, Chenguang Jia, Yong Liu, Yun Peng
OBJECTIVE: To evaluate the clinical application of a full model-based iterative reconstruction (MBIR) algorithm in the ultra-low-dose paranasal sinus CT imaging of children. MATERIALS AND METHODS: In the first phase, 16 low-dose CT dacryocystography (DCG) (80 kV/64 mAs) scans were reconstructed with MBIR and filtered back-projection (FBP) to demonstrate noise reduction capability of MBIR. MBIR images were also compared with the images of 21 standard-dose paranasal sinus patients reconstructed with adaptive statistical iterative reconstruction (ASIR) algorithm...
October 10, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28932042/small-cell-neuroendocrine-carcinoma-of-the-paranasal-sinus-with-intraoral-involvement-report-of-a-rare-case-and-review-of-the-literature
#15
Anita Spadigam, Anita Dhupar, Shaheen Syed, Shruti U Nagvekar
The diffuse neuroendocrine system continues to be an enigmatic topic of study in pathology due to its controversial embryologic origins, biology and a variety of tumors engendered. Originally thought to be localized to the classic neuroendocrine organs (pituitary, thyroid, pancreas and adrenal medulla), the neuroendocrine cells are now known to be distributed in every organ system of the body. A number of human diseases have been linked to aberrations in the functioning of the neuroendocrine cells. Neoplasms of the neuroendocrine system can thus occur in myriad primary sites and range in behavior from benign to lethal...
May 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/28893000/detection-of-dental-pathologies-in-routine-paranasal-ct-scans-a-retrospective-study
#16
Erdogan Bulbul, Bahar Yanik, Gulen Demirpolat
INTRODUCTION: Multidetector Computed Tomography (MDCT) is a widespread method for evaluating paranasal sinuses and nasal cavity in daily practice. The maxillary teeth are in field of view in a paranasal sinus CT scan and it is possible to detect dental pathologies with CT. AIM: To determine the incidence of maxillary teeth pathologies in routine paranasal sinus CT scans. MATERIALS AND METHODS: A retrospective study was conducted. Consecutive 395 paranasal sinus CT scans were evaluated...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28877060/clinicopathologic-diversity-of-undifferentiated-sarcoma-with-bcor-ccnb3-fusion-analysis-of-11-cases-with-a-reappraisal-of-the-utility-of-immunohistochemistry-for-bcor-and-ccnb3
#17
Atsuji Matsuyama, Eisuke Shiba, Yoshihisa Umekita, Kanae Nosaka, Takihiro Kamio, Hiroyuki Yanai, Chika Miyasaka, Reiko Watanabe, Ichiro Ito, Tomoko Tamaki, Shinichi Hayashi, Masanori Hisaoka
Undifferentiated sarcoma harboring the BCOR-CCNB3 fusion is characterized by its predilection to affect skeletons of adolescent males, cellular small round/spindle cell morphology, and CCNB3 immunoreactivity. We analyzed 11 cases of BCOR-CCNB3 sarcoma, 10 of which were identified in a reverse transcription-polymerase chain reaction-based screen of 85 patient samples recorded in our database as unclassified small round or spindle cell sarcomas. BCOR rearrangements were confirmed by fluorescence in situ hybridization in 8 tumors...
December 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28872554/detection-of-non-fdg-avid-residual-sinonasal-malignant-melanoma-in-the-skull-base-with-11c-choline-pet-and-contrast-enhanced-mri
#18
Chunxia Qin, Fan Hu, Maher Mohamad Rajab Arnous, Xiaoli Lan
Primary sinonasal melanoma is a rare disease. We present a case of melanoma in sinuses without abnormal F-FDG activity anywhere in the scanned portion of the body. In further assessment, C-choline PET/CT revealed high activity in the paranasal sinuses, skull base, and adjacent brain, in agreement with the high signal on contrast-enhanced T1-weighted MRI scan, which suggested the residual tumor.
September 1, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28871995/a-multicenter-study-of-carbon-ion-radiation-therapy-for-head-and-neck-adenocarcinoma
#19
MULTICENTER STUDY
Jun-Ichi Saitoh, Masashi Koto, Yusuke Demizu, Hiroaki Suefuji, Tatsuya Ohno, Hiroshi Tsuji, Tomoaki Okimoto, Yoshiyuki Shioyama, Kenji Nemoto, Takashi Nakano, Tadashi Kamada
PURPOSE: Head and neck (HN) adenocarcinoma is rare, and to date, there have been no reports of prospective studies. We retrospectively evaluated the efficacy and safety of carbon-ion radiation therapy (C-ion RT) for HN adenocarcinoma in institutions in Japan. METHODS AND MATERIALS: HN adenocarcinoma patients with N0M0 or N1M0 disease who were treated with C-ion RT at institutions in Japan between November 2003 and December 2014 were analyzed retrospectively. We enrolled 47 patients (30 male and 17 female patients; median age, 60 years) with HN adenocarcinoma...
October 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28868197/combined-simultaneous-transcranial-and-endoscopic-endonasal-resection-of-sphenoorbital-meningioma-extending-into-the-sphenoid-sinus-pterygopalatine-fossa-and-infratemporal-fossa
#20
Masahide Matsuda, Hiroyoshi Akutsu, Shuho Tanaka, Akira Matsumura
BACKGROUND: Sphenoorbital meningiomas are surgically challenging because of their nature to extend to adjacent structures. Here, we describe a case of recurrent sphenoorbital meningioma extending into the sphenoid sinus, pterygopalatine fossa, and infratemporal fossa, which was resected using combined simultaneous transcranial and endoscopic endonasal approaches. CASE DESCRIPTION: A 62-year-old man who had 15 years earlier undergone partial resection of a left sphenoorbital meningioma presented with a 1-year history of progressive proptosis of the left eye...
2017: Surgical Neurology International
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