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https://www.readbyqxmd.com/read/28449462/pulmonary-function-tests-findings-and-their-diagnostic-value-in-patients-with-igg4-related-disease
#1
Lu Cao, Yi-Bing Chen, Da-Hui Zhao, Wen-Fang Shi, Song Meng, Li-Xin Xie
BACKGROUND: IgG4-related disease (IgG4-RD) is an immune-mediated fibroinflammatory disorder that can affect most organs. To date, there have been no detailed assessments of pulmonary function in patients with IgG4-RD. In this study, we investigated pulmonary function in IgG4-RD patients and evaluated the value of pulmonary function tests (PFTs) in diagnosing IgG4-related respiratory disease (IgG4-RRD). METHODS: This was a retrospective study of 17 patients with IgG4-RD...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449229/exposure-to-texture-of-foods-for-8-month-old-infants-does-the-size-of-the-pieces-matter
#2
Saakje P da Costa, Lianne Remijn, Hugo Weenen, Carel Vereijken, Cees van der Schans
The present study examined the effect of meals varying in amount, size, and hardness of food pieces on the development of the chewing capabilities of 8-month-old infants. The study also examined changes in shivering, gagging, coughing, choking, and their ability to eat from a spoon. In an in-home setting two groups were given commercially available infant meals and fruits, purees with either less, smaller and softer or more, larger and harder pieces. Both groups were given these foods for 4 weeks and were monitored several times during this period...
April 27, 2017: Journal of Texture Studies
https://www.readbyqxmd.com/read/28449169/analysis-of-liver-tumors-using-preoperative-and-intraoperative-contrast-enhanced-ultrasound-ceus-ioceus-by-radiologists-in-comparison-to-magnetic%C3%A2-resonance-imaging-and-histopathology
#3
Severin Huf, Natascha Platz Batista da Silva, Isabel Wiesinger, Matthias Hornung, Marcus N Scherer, Sven Lang, Christian Stroszczynski, Thomas Fischer, Ernst Michael Jung
Purpose To evaluate the diagnostic significance of preoperatively and intraoperatively performed contrast-enhanced ultrasound (CEUS/IOCEUS) in the diagnosis of liver tumors in comparison to magnetic resonance imaging (MRI) and histopathology. Materials and Methods Retrospective analysis of 70/317 patients who underwent surgery for liver tumors between January 2012 and October 2015. Findings of CEUS and IOCEUS were compared to MRI. CEUS and IOCEUS were performed using multifrequency linear probes (1 - 5, 6 - 15 MHz) after bolus injection of 1 - 5 ml sulfur hexafluoride microbubbles...
May 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28449100/integrated-analysis-of-individual-codon-contribution-to-protein-biosynthesis-reveals-a-new-approach-to-improving-the-basis-of-rational-gene-design
#4
Juan C Villada, Otávio José Bernardes Brustolini, Wendel Batista da Silveira
Gene codon optimization may be impaired by the misinterpretation of frequency and optimality of codons. Although recent studies have revealed the effects of codon usage bias (CUB) on protein biosynthesis, an integrated perspective of the biological role of individual codons remains unknown. Unlike other previous studies, we show, through an integrated framework that attributes of codons such as frequency, optimality and positional dependency should be combined to unveil individual codon contribution for protein biosynthesis...
April 24, 2017: DNA Research: An International Journal for Rapid Publication of Reports on Genes and Genomes
https://www.readbyqxmd.com/read/28448845/use-of-aqueous-two-phase-peg-salt-systems-for-the-removal-of-anionic-surfactant-from-effluents
#5
Gabriella Frade Murari, Jussara Alves Penido, Heriveltom Morais da Silva, Bruno Eduardo Lôbo Baêta, Sérgio Francisco de Aquino, Leandro Rodrigues de Lemos, Guilherme Dias Rodrigues, Aparecida Barbosa Mageste
Linear alkylbenzene sulfonates (LAS) are synthetic anionic surfactants that are extensively used in many industries. As a result, large volumes of effluents containing high levels of these compounds are discharged into water bodies, causing risks to aquatic flora and fauna. Then, there is a need for environmentally safe and economically viable technologies for the removal of LAS from aqueous matrices. The present work evaluates the use of aqueous two-phase systems (ATPS) composed of PEG and sulfate salts for this purpose, considering the effects of tie line length (TLL), molar mass of polymer, and type of cation-forming salt on the partitioning behavior of LAS...
April 24, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28448691/clinical-characterization-and-genetic-analysis-of-korean-patients-with-x-linked-charcot-marie-tooth-disease-type-1
#6
Young Bin Hong, Jin-Mo Park, Jin Seok Yu, Da Hye Yoo, Da Eun Nam, Hyung Jun Park, Ji-Su Lee, Sun Hee Hwang, Ki Wha Chung, Byung-Ok Choi
Mutations in the gap junction protein beta 1 gene (GJB1) cause X-linked Charcot-Marie-Tooth disease type 1 (CMTX1). CMTX1 is representative of the intermediate type of CMT, having both demyelinating and axonal neuropathic features. We analyzed the clinical and genetic characterization of 128 patients with CMTX1 from 63 unrelated families. Genetic analysis revealed a total of 43 mutations including 6 novel mutations. Ten mutations were found from two or more unrelated families. p.V95M was most frequently observed...
April 27, 2017: Journal of the Peripheral Nervous System: JPNS
https://www.readbyqxmd.com/read/28448584/sarcopenia-in-patients-with-chronic-kidney-disease-not-yet-on-dialysis-analysis-of-the-prevalence-and-associated-factors
#7
Viviane Angelina de Souza, Dílmerson Oliveira, Sérgio Ribeiro Barbosa, José Otávio do Amaral Corrêa, Fernando Antônio Basile Colugnati, Henrique Novais Mansur, Natália Maria da Silva Fernandes, Marcus Gomes Bastos
INTRODUCTION: Sarcopenia is a chronic condition that is associated with aging and characterized by a reduction of muscle mass, strength, and function. Sarcopenia is prevalent in patients with chronic kidney disease (CKD) and associated with increased morbidity and mortality, as well as cardiovascular complications. OBJECTIVES: To investigate the prevalence of sarcopenia in patients with CKD not yet on dialysis and its correlation with clinical and laboratory variables and inflammatory markers...
2017: PloS One
https://www.readbyqxmd.com/read/28448467/chemical-composition-and-biological-activities-of-mono-and-heterofloral-bee-pollen-of-different-geographical-origins
#8
Jucilene Silva Araújo, Emerson Dechechi Chambó, Maria Angélica Pereira de Carvalho Costa, Samira Maria Peixoto Cavalcante da Silva, Carlos Alfredo Lopes de Carvalho, Leticia M Estevinho
Recent research shows variations in pollen chemical constituents and, consequently, in their therapeutic properties. Mono and multifloral bee pollen extracts were investigated for antioxidant and enzyme inhibitory activity properties, phenolic compounds and fatty acid composition. Generally, Eucalyptus spp. and multifloral extracts exhibited potent inhibitory activity against α-amylase, acetylcholinesterase, tyrosinase, lipoxygenase, lipase and hyaluronidase. On the other hand, Miconia spp. demonstrated higher antihemolytic activity...
April 27, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28447864/the-use-of-cyproterone-acetate-ethinyl-estradiol-in-hyperandrogenic-skin-symptoms-a-review
#9
J Bitzer, T Römer, A Lopes da Silva Filho
INTRODUCTION: Hyperandrogenism affects approximately 10-20% of women of reproductive age. Hyperandrogenic skin symptoms such as hirsutism, acne, seborrhea and alopecia are associated with significant quality of life and psychological impairment. Women with abnormalities in androgen metabolism may have accompanying anovulation and/or polycystic ovary syndrome (PCOS), both of which have reproductive and metabolic implications if left untreated. Cyproterone acetate (CPA), combined with ethinylestradiol (EE), is indicated for the treatment of moderate to severe acne related to androgen-sensitivity (with or without seborrhea) and/or hirsutism, in women of reproductive age...
April 27, 2017: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/28447861/screening-and-early-detection-of-oral-cancer-current-controversies
#10
Leonardo Victor Galvão-Moreira, Maria Carmen Fontoura Nogueira Da Cruz
Some evidence suggests that the early detection of oral cancer (OC) during surveillance might improve survival rates. In addition to this, interventions aimed at enhancing public awareness and knowledge of signs, symptoms and risk factors of OC are thought to decrease the burden of disease. Nevertheless, there is much controversy with regard to the cost-effectiveness of population-based strategies for OC screening. Here, we present and briefly discuss timely findings that have put under scrutiny the applicability of approaches targeted at the early identification of patients with OC...
April 27, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28447763/berberine-protects-against-diet-induced-obesity-through-regulating-metabolic-endotoxemia-and-gut-hormone-levels
#11
Jian Hui Xu, Xing Zhen Liu, Wei Pan, Da Jin Zou
Systemic inflammation, which can be induced by metabolic endotoxemia, and corresponding high‑fat diet‑mediated metabolic disorders are associated with gut microbiota. In the present study reverse transcription-polymerase chain reaction, immunofluorescence, pyrosequencing, ELISA and Oil Red O staining were performed to assess whether berberine can protect against diet-induced obesity, through modulating the gut microbiota and consequently improving metabolic endotoxemia and gastrointestinal hormone levels...
March 14, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28447492/statistical-aspects-of-near-infrared-spectroscopy-for-the-characterization-of-errors-and-model-building
#12
Alessandra da Rocha Duailibe Monteiro, Thiago de Sá Feital, José Carlos Pinto
Due to the complex nature of near-infrared (NIR) spectra, it is usually very difficult to provide quantitative interpretations of spectral data. As a consequence, careful building and validation of calibration models are of fundamental importance prior to development of useful applications of NIR technologies. For this reason, this work presents a statistical study about the NIR spectroscopy, analyzing the NIR behavior when the experimental conditions are changed. Near-infrared spectra were measured at different temperatures and stirring velocities for systems containing a pure solvent and a suspension of polymer powder in order to perform the error analysis...
January 1, 2017: Applied Spectroscopy
https://www.readbyqxmd.com/read/28447488/observation-of-the-162-dy-164-dy-isotope-shift-for-the-0-%C3%A2-16%C3%A2-717-79%C3%A2-cm-1-optical-transition
#13
Luiz Felipe Nardin Barreta, Alessandro Rogério Victor, Patrícia Bueno, Jhonatha Ricardo Dos Santos, Carlos Alberto Barbosa da Silveira, José Wilson Neri, Jonas Jakutis Neto, Maria Esther Sbampato, Marcelo Geraldo Destro
In this work, we report a newly observed isotope shift between (162)Dy and (164)Dy isotopes for the 0 → 16 717.79 cm(-1) (598.003 nm) optical transition. We compared the newly observed results against two other lines (597.452 nm and 598.859 nm), which we measured in this work, and were already reported in the literature. The newly observed 162-164 Dy isotope shift, shows at least a 20% larger isotope shift than the isotope shifts for the other two lines investigated. The larger 162-164 isotope shift observed for the 598...
January 1, 2017: Applied Spectroscopy
https://www.readbyqxmd.com/read/28447448/lanthanide-organic-gels-logs-as-a-multifunctional-supramolecular-smart-platform
#14
José Yago Rodrigues Silva, Leonis Lourenço da Luz, Filipe Gabriel Martinez Mauricio, Iane Bezerra Vasconcelos Alves, Jamylle Nunes de Souza Ferro, Emiliano Barreto, Ingrid Tavora Weber, Walter Mendes de Azevedo, Severino Alves Júnior
A multifunctional smart supramolecular platform based on a lanthanide-organic hydrogel is presented. This platform, which provides unique biocompatibility and tunable optical properties, is synthesized by a simple, fast and reproducible eco-friendly microwave-assisted route. Photoluminescent properties enable the production of coated light-emitting diodes (LED), unique luminescent barcodes dependent on the excitation wavelength and thin-films for use in tamper seals. Moreover, piroxicam entrapped in hydrogel acts as a transdermal drug release device efficient in inhibiting edemas compared to a commercial reference...
April 27, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28447317/neuroimaging-findings-of-postnatally-acquired-zika-virus-infection-a-pictorial-essay
#15
Mohammad Zare Mehrjardi, Guillaume Carteaux, Andrea Poretti, Morteza Sanei Taheri, Sonia Bermudez, Heron Werner, Luiz Celso Hygino da Cruz
Zika virus (ZIKV) is a mosquito-borne arbovirus from the Flaviviridae family, first discovered in 1947. There has been no report of severe complications caused by this virus in humans until recently. However, it is confirmed now that prenatally acquired ZIKV infection may cause severe congenital brain abnormalities in the infected fetuses. In addition, there has been an increasing number of reports during recent years about the causal relationship between postnatally acquired ZIKV infection and severe neurologic complications (mostly immune-mediated ones)...
April 26, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/28447265/nadp-dependent-isocitrate-dehydrogenase-from-a-psychrophilic-bacterium-psychromonas-marina
#16
Ryo Hirota, Kango Tsubouchi, Yasuhiro Takada
The gene encoding NADP(+)-dependent isocitrate dehydrogenase (IDH; EC 1.1.1.42) of a psychrophilic bacterium, Psychromonas marina, was cloned and sequenced. The open reading frame of the gene encoding IDH of P. marina (PmIDH) was 2229 bp in length and corresponded to a polypeptide composed of 742 amino acids. The molecular mass of IDH was calculated as 80,426 Da. The deduced amino acid sequence of PmIDH exhibited high degrees of homology with the monomeric IDH from other bacteria such as Colwellia maris (62% identity) and Azotobacter vinelandii (AvIDH) (64%)...
April 26, 2017: Extremophiles: Life Under Extreme Conditions
https://www.readbyqxmd.com/read/28447109/diagnostic-nomogram-for-gallbladder-wall-thickening-mimicking-malignancy-using-contrast-enhanced-ultrasonography-or-multi-detector-computed-tomography
#17
Li-Da Chen, Yang Huang, Xiao-Hua Xie, Wei Chen, Quan-Yuan Shan, Ming Xu, Jin-Ya Liu, Zhi-Qiang Nie, Xiao-Yan Xie, Ming-De Lu, Shun-Li Shen, Wei Wang
OBJECTIVES: To establish a diagnostic nomogram using contrast-enhanced ultrasonography (CEUS) in gallbladder wall thickening mimicking malignancy and compare with multi-detector computed tomography (MDCT). METHODS: Seventy-two patients with gallbladder wall thickening on B-mode ultrasonography (BUS) were examined by CEUS to develop independent predictors for diagnosing gallbladder carcinoma. Among the 72 cases, 48 patients underwent both CEUS and MDCT. The diagnostic performances of different sets of CEUS criteria and MDCT were compared...
April 26, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28446902/modulation-of-macrophage-responses-by-cmx-a-fusion-protein-composed-of-ag85c-mpt51-and-hspx-from-mycobacterium-tuberculosis
#18
Adeliane C da Costa, Danilo P de Resende, Bruno de P O Santos, Karina F Zoccal, Lúcia H Faccioli, André Kipnis, Ana P Junqueira-Kipnis
Mycobacterium bovis Bacillus Calmette-Guérin (BCG) is a vaccine used to prevent tuberculosis (TB). Due to the poor protection conferred by BCG in adults, new, more effective formulations have been developed. A recombinant BCG vaccine expressing the CMX fusion protein Ag85c_MPT51_HspX (rBCG-CMX) induced Th1 and Th17 responses and provided better protection than BCG. It has been shown that Mycobacterium smegmatis expressing CMX also induces better protection than BCG and is a strong macrophage activator. The aim of the present study was to evaluate macrophage activation by the recombinant CMX fusion protein and by rBCG-CMX and to evaluate their ability to generate vaccine-specific immune responses...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28446900/bioactive-molecule-from-streptomyces-sp-mitigates-mdr-klebsiella-pneumoniae-in-zebrafish-infection-model
#19
Lalitha Cheepurupalli, Thiagarajan Raman, Sudarshan S Rathore, Jayapradha Ramakrishnan
The emergence and spread of multi-drug resistant (MDR) especially carbapenem-resistant Klebsiella pneumoniae is a major emerging threat to public health, leading to excess in mortality rate as high as 50-86%. MDR K. pneumoniae manifests all broad mechanisms of drug resistance, hence development of new drugs to treat MDR K. pneumoniae infection has become a more relevant question in the scientific community. In the present study a potential Streptomyces sp. ASK2 was isolated from rhizosphere soil of medicinal plant...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28446680/non-structural-protein-l-species-specificity-supports-a-mouse-origin-for-vilyuisk-human-encephalitis-virus
#20
Melissa Drappier, Fred R Opperdoes, Thomas Michiels
Vilyuisk human encephalitis virus (VHEV) is a picornavirus related to Theiler's murine encephalomyelitis virus (TMEV). VHEV was isolated from human material passaged in mice. Whether this VHEV is from human or mouse origin is therefore unclear. We took advantage of the species-specific activity of the non-structural L* protein of theiloviruses to track the origin of TMEV isolates. TMEV L* inhibits RNase L, the effector enzyme of the interferon pathway. Using co-immunoprecipitation and functional RNase L assays, the species-specificity of RNase L antagonism was tested for L* from a mouse (DA) and a rat (RTV-1) TMEV strain as well as for VHEV...
April 26, 2017: Journal of Virology
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