Colchicine choroidal detachment

A young patient is described who presented with sudden visual loss in the left eye quickly followed by proliferative retinopathy with retinal detachment and thrombotic glaucoma. He developed similar initial symptoms in the right eye but has now made a complete recovery in that eye on systemic steroids, oral acyclovir, cyclosporin A and colchicine. Pathological examination of the left eye revealed inflammation in the ciliary body, retina and choroid with prominent eosinophils. The nature of the initial insult and the possible role of the eosinophils are discussed...