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https://www.readbyqxmd.com/read/29342438/vitreoretinal-complications-and-outcomes-in-92-eyes-undergoing-surgery-for-modified-osteo-odonto-keratoprosthesis-a-10-year-review
#1
Pukhraj Rishi, Ekta Rishi, Vishvesh Agarwal, Sridevi Nair, Geetha Iyer, Bhaskar Srinivasan, Shweta Agarwal
PURPOSE: To analyze vitreoretinal (VR) complications and treatment outcomes in eyes undergoing modified osteo-odonto-keratoprosthesis (OOKP) surgery. DESIGN: Retrospective case series. PARTICIPANTS: All patients who underwent modified OOKP (mOOKP) surgery at a tertiary eye-care center from March 2003 to February 2013 were included. METHODS: Medical records were reviewed for relevant medical history, best-corrected visual acuity (BCVA), slit-lamp examination, ultrasound scan, oral examination findings, and VR complications...
January 13, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29342012/diffuse-chorioretinopathy-without-serous-detachment-associated-with-cardiac-transplantation
#2
Michael F Marmor
PURPOSE: To analyze an unusual case of widespread chorioretinopathy after cardiac transplantation for its potential etiology and clinical significance. METHODS: Clinical examinations included widefield and macular color and fundus autofluorescence photography, spectral domain optical coherence tomography, fluorescein angiography and indocyanine green angiography, full-field electroretinography, and Goldmann visual fields. PATIENT: A 44-year-old Hispanic woman was referred to rule out retinitis pigmentosa...
January 16, 2018: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29333905/linear-nevus-sebaceous-syndrome-presenting-as-circumscribed-choroidal-hemangioma
#3
Jose J Echegaray, Rachel Chen, Claudine Bellerive, Arun D Singh
A 4-year-old female with a unilateral circumscribed choroidal hemangioma and secondary total exudative retinal detachment. A nasal skin scar-like lesion incised to confirm a histopathologic diagnosis of linear nevus sebaceous. Further imaging disclosed asymmetry of the lateral ventricle frontal horns, suggestive of the diagnosis of linear nevus sebaceous syndrome. The choroidal hemangioma was treated with I-125 episcleral brachytherapy (apical dose of 45 Gy). At 6 months post-radiation, the tumor showed regression with total resolution of exudative retinal detachment...
January 15, 2018: Ophthalmic Genetics
https://www.readbyqxmd.com/read/29282403/epiretinal-membrane-in-dome-shaped-macula-complicated-with-serous-retinal-detachment-transient-efficacy-of-surgery
#4
Guillaume Soudier, Alain Gaudric, Vincent Gualino, Mathieu Nardin, Claude Speeg-Schatz, David Gaucher
Dome-shaped macula (DSM) is an entity recently described as a convex anterior protrusion of the macular area within a posterior myopic staphyloma. Specific complications were associated with DSM, like serous retinal detachment (SRD). We describe a woman presenting with a decreased vision at 20/50. SD-OCT scans were performed, showing a macular bulge. SRD was present and an epiretinal membrane could also be observed. Fluorescein angiography and indocyanin green angiography did not show any leakage nor choroidal neovascularization...
September 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29280938/choroidal-tumor-biopsy-a-review-of-the-current-state-and-a-glance-into-future-techniques
#5
Avni P Finn, Miguel A Materin, Prithvi Mruthyunjaya
PURPOSE: To review the indications for and the methods of obtaining biopsies in eyes with uveal melanoma. In addition, this review provides recommendations for avoiding biopsy-related complications and discusses the future directions of biopsy techniques for uveal melanoma. METHODS: This review is based on a presentation by the authors (PM and MM) at the 2017 Duke Advanced Vitreoretinal Surgery Course and an extensive literature review using PubMed. RESULTS: Transscleral and transvitreal fine-needle aspiration biopsy, and transvitreal vitrectomy-assisted biopsy techniques are described...
December 26, 2017: Retina
https://www.readbyqxmd.com/read/29279658/macular-hole-secondary-to-polypoidal-choroidal-vasculopathy
#6
Prabu Baskaran, Utsab Pan
We report a case of polypoidal choroidal vasculopathy (PCV) presented with massive submacular hemorrhage (SMH) and macular hole (MH). Spectral domain optical coherence tomography confirmed the presence of MH along with SMH and also revealed an extrafoveal-notched pigment epithelium detachment (PED) suggestive of PCV. Urgent pneumatic displacement with perfluoropropane (C3F8) was done. Indocyanine green angiography done 3 weeks later showed polyps in the superonasal macula corresponding to PED. Extrafoveal polyps were treated with laser photocoagulation...
July 2017: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/29275341/qualitative-and-quantitative-assessment-of-posterior-segment-optical-coherence-tomography-images-using-standard-photos-the-liwan-eye-study
#7
Sean K Wang, Xinxing Guo, Ou Xiao, Yanxian Chen, Ran Liu, Wenyong Huang, Mingguang He
BACKGROUND/AIMS: To develop a standardised grading scheme, using standard photos, for spectral-domain ocular coherence tomography (SD-OCT) images of the posterior eye and evaluate the interobserver agreement among trained ophthalmologists in identifying pathological changes. METHODS: Subjects were recruited from Liwan District, Guangzhou, with SD-OCT data collection from June 2013 to November 2013 as part of 10-year follow-up visits from the Liwan Eye Study. All subjects underwent SD-OCT imaging of the macula with scanning lines analysed by two ophthalmologists to assess for the presence of 12 different posterior segment lesions...
December 22, 2017: BMJ Open
https://www.readbyqxmd.com/read/29260502/posttraumatic-acute-choroidopathy
#8
Özlem Dikmetas, Annegret Abaza, Faik Gelisken
PURPOSE: To report a case of acute choroidopathy following a blunt ocular trauma. METHODS: Ocular examination included dilated fundus examination and optical coherence tomography enhanced depth imaging (OCT-EDI). PATIENTS: Single-patient case report. CASE REPORT: A 10-year-old boy was referred following a blunt trauma to the right eye. The visual acuity diminished to 20/200 and mild hemorrhage was found in the anterior chamber...
December 19, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29243035/systemic-lupus-erythematosus-and-ocular-involvement-an-overview
#9
REVIEW
Rosanna Dammacco
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease of undefined etiology and with remarkably heterogeneous clinical features. Virtually any organ system can be affected, including the eye. SLE-related eye involvement can be diagnosed in approximately one-third of the patients and is usually indicative of disease activity. An early diagnosis and the adoption of suitable therapeutic measures are necessary to prevent sight-threatening consequences, especially in patients with juvenile SLE. Periocular lesions, such as eyelid involvement and orbital inflammation, are relatively rare and, in case of orbital masses, may require a biopsy control...
December 14, 2017: Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/29230338/optical-coherence-tomography-angiography-of-punctate-inner-choroidopathy
#10
Blake M Hampton, Christopher M Aderman, Harry W Flynn, Jayanth Sridhar
Purpose: To report a case of bilateral choroidal neovascularization (CNV) in punctate inner choroidopathy (PIC) visualized utilizing optical coherence tomography angiography (OCT-A). Methods: Case report. Results: A 29-year-old woman presented with new visual symptoms in both eyes. Fundoscopic exam revealed bilateral multifocal, small, well-defined lesions consistent with PIC. Optical coherence tomography demonstrated subretinal fluid and retinal pigment epithelium detachments (RPEDs) in both eyes...
2017: Case Reports in Ophthalmological Medicine
https://www.readbyqxmd.com/read/29219956/surgical-outcomes-of-preoperative-steroid-for-rhegmatogenous-retinal-detachment-with-associated-choroidal-detachment
#11
A Denwattana, S Prakhunhungsit, S Thoongsuwan, N Rodanant, N Phasukkijwatana
PurposeTo investigate the effect of preoperative steroid on anatomical and functional outcomes of vitrectomy in patients with rhegmatogenous retinal detachment with associated choroidal detachment (RRD-CD), a rare but particular type of RRD.Patients and methodsThis retrospective cohort study included RRD-CD patients at Siriraj Hospital during January 2005 to December 2014. Patients with preexisting uveitis or RRD with giant retinal tears were excluded. Preoperative, intraoperative, and postoperative data were reviewed and analyzed...
December 8, 2017: Eye
https://www.readbyqxmd.com/read/29219932/cuticular-drusen-in-an-indigenous-australian
#12
William J Cunningham, Chandrakumar Balaratnasingam, Yi Chen, Fred K Chen
BACKGROUND/PURPOSE: To report a case of cuticular drusen in an indigenous Australian. METHODS: A 37-year-old indigenous (aboriginal) Australian woman from a remote Western Australian town presented with a 2-month history of vision loss. Clinical history, examination, and multimodal retinal imaging data from spectral domain optical coherence tomography, fundus autofluorescence, fluorescein angiography, and indocyanine green angiography were analyzed. RESULTS: Multimodal imaging confirmed cuticular drusen complicated by a right choroidal neovascularization with pigment epithelial detachment and a left foveal vitelliform lesion...
December 5, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29219899/clinical-outcomes-using-oversized-back-plates-in-type-i-boston-keratoprosthesis
#13
Aaron R Kaufman, Andrea Cruzat, Kathryn A Colby
OBJECTIVES: To examine clinical outcomes of oversized titanium back plates in type I Boston keratoprosthesis (KPro) implantation. METHODS: Retrospective study of 22 sequential eyes (20 patients) undergoing type I KPro implantation with an oversized titanium back plate (larger than trephined wound diameter by 1.0 mm or more), performed by a single surgeon (K.A.C.) from June 2010 to November 2014. Data were collected regarding preoperative eye characteristics, surgical details, and postoperative clinical outcomes...
December 5, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/29217514/novel-ocular-toxicity-associated-with-fibroblast-growth-factor-receptor-fgfr-inhibitors-in-cancer-treatment-observational-case-series
#14
Daniel Velazquez-Villoria, Analia Azaro, Jordi Rodon, Cinta Hierro, Danai Kyriakou, Jose Garcia-Arumi, Miguel Angel Zapata
AIMS: To describe novel ocular toxicity in patients with metastatic cancer undergoing chemotherapy with fibroblast growth factor receptor (FGFR) inhibitors. METHODS: This observational case series study included five patients with advanced cancer who received selected pan-FGFR inhibitors as single chemotherapy in the framework of a dose-finding study and phase I and phase II clinical studies. In all cases, subfoveal neurosensory retinal detachment was diagnosed...
December 7, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29212537/association-of-arms2-genotype-with-response-to-anti-vascular-endothelial-growth-factor-treatment-in-polypoidal-choroidal-vasculopathy
#15
Un Chul Park, Joo Young Shin, Hum Chung, Hyeong Gon Yu
BACKGROUND: To investigate whether genetic risk variants for age-related macular degeneration (AMD) are associated with response to intravitreal anti-vascular endothelial growth factor (VEGF) in polypoidal choroidal vasculopathy (PCV) patients. METHODS: This prospective cohort study included 95 treatment-naïve patients that underwent anti-VEGF treatment for PCV for 12 months. Patients were genotyped for 10 single nucleotide polymorphisms in eight AMD-relevant genes...
December 7, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29212288/failure-of-ocular-photodynamic-therapy-for-secondary-choroidal-metastasis-a-case-report-and-literature-review
#16
Rui Hua, Wenya Li, Weiwei Wu, Jun Tao, Qing Peng
The choroid is the most common site for intraocular metastatic disease. Photodynamic therapy (PDT) can effectively destroy malignant tissue and induce anti-tumor activity. Recent publications support its use as an effective therapy for the treatment of choroidal metastases, especially in the subfoveal region, resulting in subsequent vision preservation or improvement. Here, we introduce a case of choroidal metastasis, secondary to primary lung cancer. The progression of choroidal metastasis after PDT was followed up using spectral domain optical coherence tomography with point-to-point follow-up...
November 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/29205744/rabbits-with-naturally-occurring-cataracts-referred-for-phacoemulsification-and-intraocular-lens-implantation-a-preliminary-study-of-12-cases
#17
Rick F Sanchez, Richard Everson, Joanna Hedley, Charlotte Dawson, Richard Lam, Simon L Priestnall, Alejandra Garcia de Carellan, Cristina de Miguel, Christopher Seymour
OBJECTIVE: To describe the presentation of 15 rabbits with naturally occurring cataracts referred for phacoemulsification surgery, the procedure in 13 cases and the follow-up in 12. ANIMALS INCLUDED: Fifteen rabbits (30 eyes), nine of which stopped following visual cues in association with cataract progression. MATERIALS AND METHODS: Rabbits underwent preoperative ophthalmic and ocular ultrasound examination. RESULTS: Thirteen rabbits (22 eyes) had mature cataracts...
December 4, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29193812/exploring-literature-based-definitions-of-hypotony-following-glaucoma-filtration-surgery-and-the-impact-on-clinical-outcomes
#18
Ali Abbas, Pavi Agrawal, Anthony J King
PURPOSE: To highlight the variations in published definitions of hypotony and their impact on reported clinical outcomes. To propose a revised definition, focusing on clinically significant hypotony (CH). METHODS: Literature review of hypotony definitions published between January 2010 and December 2015 was carried out. Numerical definitions for hypotony, its onset, duration and associated clinical signs were recorded. Each definition was applied to surgical outcomes data collected prospectively from a cohort of 300 glaucoma patients treated at a single centre...
November 29, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29190243/factors-associated-with-serous-retinal-detachment-in-highly-myopic-eyes-with-vertical-oval-shaped-dome
#19
Antonio García-Ben, María J Morillo Sanchez, Ana Gonzalez Gómez, Ignacio García-Basterra, Antonio Soler García, Jose M García-Campos
PURPOSE: This study investigated factors associated with persistent serous retinal detachment in highly myopic eyes with vertical oval-shaped domes. METHODS: Twenty-eight highly myopic patients (40 eyes) with smooth macular elevations related to a vertical oval-shaped dome were recruited. Serous retinal detachment was investigated; 11 eyes had persistent submacular fluid (study group) and 29 eyes lacked submacular fluid (control group). All patients underwent complete ophthalmologic examinations, including axial-length measurement and fluorescein angiography...
November 22, 2017: Retina
https://www.readbyqxmd.com/read/29185844/postoperative-complications-of-scleral-buckling
#20
Thanos D Papakostas, Demetrios Vavvas
Scleral buckling has an important role in the repair of certain categories of rhegmatogenous retinal detachments. These include detachments in young phakic patients, detachments associated with dialysis, and also in conjuction with vitrectomy in patients who have sustained trauma or have developed proliferative vitreoretinopathy. However, it can be associated with significant postoperative complications. The most important ones are refractive change, intrusion or extrusion, infection, globe ischemia, and choroidal detachments, amongst others...
November 29, 2017: Seminars in Ophthalmology
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