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https://www.readbyqxmd.com/read/29845623/long-term-clinical-evaluation-of-hair-clearance-in-darkly-pigmented-individuals-using-a-novel-diode1060-nm-wavelength-with-multiple-treatment-handpieces-a-prospective-analysis-with-modeling-and-histological-findings
#1
Edward V Ross, Omar A Ibrahimi, Suzanne Kilmer
OBJECTIVE: The purpose of this study was to determine the efficacy and safety of a 1060 nm diode laser system with multiple handpieces for permanent hair reduction. STUDY DESIGN: An open-label, prospective, multi-center study of adult subjects (≥18 years old) of any skin type, having dark brown or black hairs at the areas to be treated and seeking to permanently remove hair underwent six treatment sessions, at 4 to 6 weeks intervals with either a 1060 nm chilled sapphire tip or seven treatment sessions, at 6 weeks interval with a large spot vacuum based handpiece...
May 30, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29791375/tunable-double-mode-sensor-for-multi-gas-detection-based-on-the-external-cavity-diode-laser
#2
Ismail Bayrakli
An optoelectronic sensor system based on a thermoelectrically cooled (TEC) continuous-wave (CW) double-mode external-cavity diode laser (ECDL) is demonstrated for a multi-gas analysis in this paper. An ECDL that can simultaneously emit at two different wavelengths in the range from 1275 to 1340 nm was utilized as the excitation source for molecule absorption. Each wavelength can be independently tuned. The ECDL was combined with an off-axis cavity-enhanced absorption spectroscopy (OA-CEAS) cell to perform multi-gas sensing...
May 20, 2018: Applied Optics
https://www.readbyqxmd.com/read/29782304/role-of-in-vivo-reflectance-confocal-microscopy-in-the-analysis-of-melanocytic-lesions
#3
Elena-Daniela Serban, Francesca Farnetani, Giovanni Pellacani, Maria Magdalena Constantin
Worldwide melanoma incidence and mortality are increasing (1). Despite the ongoing research, advanced melanoma is still incurable; therefore, the most appropriate solution seems to be early detection combined with complete surgical excision (2). Since the diagnostic protocol of suspicious lesions includes a complete excision with safety margins (2), the problem of unnecessary scarring is significant. The real challenge in this case is to have a properly formulated diagnosis before acquiring a biopsy. Currently available non-invasive techniques are coherence tomography, digital dermoscopy, and reflectance confocal microscopy...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29780505/macrophage-mediated-delivery-of-light-activated-nitric-oxide-prodrugs-with-spatial-temporal-and-concentration-control
#4
Michael A Evans, Po-Ju Huang, Yuji Iwamoto, Kelly N Ibsen, Emory M Chan, Yutaka Hitomi, Peter C Ford, Samir Mitragotri
Nitric oxide (NO) holds great promise as a treatment for cancer hypoxia, if its concentration and localization can be precisely controlled. Here, we report a "Trojan Horse" strategy to provide the necessary spatial, temporal, and dosage control of such drug-delivery therapies at targeted tissues. Described is a unique package consisting of (1) a manganese-nitrosyl complex, which is a photoactivated NO-releasing moiety (photoNORM), plus Nd3+ -doped upconverting nanoparticles (Nd-UCNPs) incorporated into (2) biodegradable polymer microparticles that are taken up by (3) bone-marrow derived murine macrophages...
April 21, 2018: Chemical Science
https://www.readbyqxmd.com/read/29772045/ocular-tolerance-of-contemporary-electronic-display-devices
#5
Andrew J Clark, Paul Yang, Khizer R Khaderi, Andrew A Moshfeghi
Electronic displays have become an integral part of life in the developed world since the revolution of mobile computing a decade ago. With the release of multiple consumer-grade virtual reality (VR) and augmented reality (AR) products in the past 2 years utilizing head-mounted displays (HMDs), as well as the development of low-cost, smartphone-based HMDs, the ability to intimately interact with electronic screens is greater than ever. VR/AR HMDs also place the display at much closer ocular proximity than traditional electronic devices while also isolating the user from the ambient environment to create a "closed" system between the user's eyes and the display...
May 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29762604/terabit-optical-ofdm-superchannel-transmission-via-coherent-carriers-of-a-hybrid-chip-scale-soliton-frequency-comb
#6
Yong Geng, Xiatao Huang, Wenwen Cui, Yun Ling, Bo Xu, Jin Zhang, Xingwen Yi, Baojian Wu, Shu-Wei Huang, Kun Qiu, Chee Wei Wong, Heng Zhou
We demonstrate seamless channel multiplexing and high bitrate superchannel transmission of coherent optical orthogonal frequency division multiplexing (CO-OFDM) data signals utilizing a dissipative Kerr soliton (DKS) frequency comb generated in an on-chip microcavity. Aided by comb line multiplication through Nyquist pulse modulation, the high stability and mutual coherence among mode-locked Kerr comb lines are exploited for the first time, to the best of our knowledge, to eliminate the guard intervals between communication channels and achieve full spectral density bandwidth utilization...
May 15, 2018: Optics Letters
https://www.readbyqxmd.com/read/29714294/wavelength-modulation-technique-based-photoacoustic-spectroscopy-for-multipoint-gas-sensing
#7
Z L Wang, C W Tian, Q Liu, J Chang, Q D Zhang, C G Zhu
A multipoint gas sensing scheme based on photoacoustic spectroscopy was proposed. Multiple photoacoustic spectroscopy (PAS) gas cells (resonant frequency f0 =5.0  kHz) were connected in series for the multipoint gas sensing with wavelength modulation technique. The PAS signal was excited by modulating the tunable distributed feedback laser diode wavelength at f0 /2 using a changing driving current. The gas concentration of each gas cell was obtained by the PAS signal, which was demodulated by the lock-in amplifier...
April 10, 2018: Applied Optics
https://www.readbyqxmd.com/read/29609357/implementation-of-a-violet-scheimpflug-lidar-system-for-atmospheric-aerosol-studies
#8
Liang Mei, Zheng Kong, Peng Guan
A violet Scheimpflug lidar system employing a 1-W 407-nm multimode laser diode is developed for remote sensing of atmospheric aerosols. The laser beam of the laser diode that is transmitted into atmosphere has been investigated in detail and a cylindrical lens pair is designed to improve the geometrical transmission efficiency. A measurement scheme with automatic exposure as well as a generalized signal processing method are established to optimize the signal-to-noise ratio of lidar signals. The performance of the violet Scheimpflug lidar system has been evaluated during a six-day continuous measurement campaign on a near horizontal path...
March 19, 2018: Optics Express
https://www.readbyqxmd.com/read/29609345/time-resolved-fabry-perot-measurements-of-cavity-temperature-in-pulsed-qcls
#9
S Gundogdu, H S Pisheh, A Demir, M Gunoven, A Aydinli, C Sirtori
Temperature rise during operation is a central concern of semiconductor lasers and especially difficult to measure during a pulsed operation. We present a technique for in situ time-resolved temperature measurement of quantum cascade lasers operating in a pulsed mode at ~9.25 μm emission wavelength. Using a step-scan approach with 5 ns resolution, we measure the temporal evolution of the spectral density, observing longitudinal Fabry-Perot modes that correspond to different transverse modes. Considering the multiple thin layers that make up the active layer and the associated Kapitza resistance, thermal properties of QCLs are significantly different than bulk-like laser diodes where this approach was successfully used...
March 19, 2018: Optics Express
https://www.readbyqxmd.com/read/29550021/withdrawn-ethical-and-legal-ramifications-of-using-diode-lasers-for-nonsurgical-periodontal-therapy
#10
Robert A Convissar
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal.
March 14, 2018: Journal of the American Dental Association
https://www.readbyqxmd.com/read/29529762/narrow-linewidth-quasi-continuous-wave-ase-source-based-on-a-multiple-pass-nd-yag-zigzag-slab-amplifier-configuration
#11
Xiaoming Chen, Yanhua Lu, Hao Hu, Lixin Tong, Lei Zhang, Yi Yu, Juntao Wang, Huaijin Ren, Liu Xu
We present investigations into a narrow-linewidth, quasi-continuous-wave pulsed all-solid-state amplified spontaneous emission (ASE) source by use of a novel multiple-pass zigzag slab amplifier. The SE fluorescence emitted from a Nd:YAG slab active medium acts as the seed and is amplified back and forth 8 times through the same slab. Thanks to the angular multiplexing nature of the zigzag slab, high-intensity 1064-nm ASE output can be produced without unwanted self-lasing in this configuration. Experimentally, the output energy, optical conversion efficiency, pulse dynamics, spectral property, and beam quality of the ASE source are studied when the Nd:YAG slab end-pumped by two high-brightness laser diode arrays...
March 5, 2018: Optics Express
https://www.readbyqxmd.com/read/29483499/multiple-field-interstitial-photodynamic-therapy-of-subcutaneously-transplanted-cholangiocellular-carcinoma-rs-1-in-rats
#12
D A Tzerkovsky
The aim of present study was to investigate an antitumor efficacy of multiple-field interstitial photodynamic therapy (iPDT) in vivo. MATERIALS AND METHODS: The study was performed on 15 white random-bred rats with subcutaneously transplanted cholangiocellular carcinoma RS-1. Chlorine-based photosensitizer (PS) Ce6CPPPS was administered via single injection at a dose of 2.5 mg/kg into the animal's caudal vein. Photoirradiation (PI) of tumors was carried out 3 h after PS administration using 7 optical fibers SMA-905 with diode laser with 660 ± 5 nm wavelength at exposure doses of 150 and 300 J/cm² with 0...
July 2017: Experimental Oncology
https://www.readbyqxmd.com/read/29476546/a-randomized-split-scalp-study-comparing-calcipotriol-assisted-mal-pdt-with-conventional-mal-pdt-for-the-treatment-of-actinic-keratosis
#13
L Torezan, B Grinblat, M Haedersdal, N Valente, C Festa-Neto, R M Szeimies
BACKGROUND: Topical photodynamic therapy (PDT) is an approved treatment for actinic keratosis (AK). To enhance the efficacy of PDT for AKs, physical (ablative lasers and microneedling) and chemical (pro-differentiating drugs) pretreatments have been suggested. OBJECTIVES: To compare the efficacy and safety of the combination of topical calcipotriol (CAL) before methylaminolevulinate (MAL)-PDT for AKs of the scalp versus conventional MAL-PDT in a randomized controlled-clinical trial...
February 24, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29469836/rapid-super-resolution-confocal-microscopy-through-virtual-structured-detection-based-on-serial-scanning-in-array
#14
Limin Zou, He Ni, Qingyuan Guo, Qing Yan, Xuemei Ding
To improve the imaging speed of a confocal microscope with virtual structured detection, we have designed an optical system with rigid coordination control of the CCD, galvanometer scanner, and laser diode. In this system, the width of the coherent transfer function expands, which enhances the lateral resolution by a factor of 1.4. Also, the temporal image sequence is transformed to a spatial one so that multiple images can be acquired during a single exposure period of the CCD. This method increases the system imaging speed 25-fold at least, and an even higher speed can be achieved by further increasing the number of spots recorded during a single exposure period...
February 20, 2018: Applied Optics
https://www.readbyqxmd.com/read/29425175/laser-based-monitoring-of-ch%C3%A2-co%C3%A2-nh%C3%A2-and-h%C3%A2-s-in-animal-farming-system-characterization-and-initial-demonstration
#15
Dorota Stachowiak, Piotr Jaworski, Paweł Krzaczek, Grzegorz Maj, Michał Nikodem
In this paper, we present a system for sequential detection of multiple gases using laser-based wavelength modulation spectroscopy (WMS) method combined with a Herriot-type multi-pass cell. Concentration of hydrogen sulfide (H₂S), methane (CH₄), carbon dioxide (CO₂), and ammonia (NH₃) are retrieved using three distributed feedback laser diodes operating at 1574.5 nm (H₂S and CO₂), 1651 nm (CH₄), and 1531 nm (NH₃). Careful adjustment of system parameters allows for H₂S sensing at single parts-per-million by volume (ppmv) level with strongly reduced interference from adjacent CO₂ transitions even at atmospheric pressure...
February 9, 2018: Sensors
https://www.readbyqxmd.com/read/29399308/comparison-of-tooth-color-change-after-bleaching-with-conventional-and-different-light-activated-methods
#16
Sima Shahabi, Hadi Assadian, Alireza Mahmoudi Nahavandi, Hanieh Nokhbatolfoghahaei
Introduction: The demand for esthetic dental treatments is increasing in recent years mainly due to improved oral hygiene and better maintenance of oral health and teeth in older individuals. Bleaching of discolored anterior teeth is the most popular among esthetic dental treatments. Even individuals with sound teeth and adequate esthetics seek to have whiter teeth in the anterior region. The aim of this study was to evaluate tooth color changes following conventional in-office bleaching techniques compared to light-activated methods using different light sources...
2018: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29380865/nasopharyngeal-sialoceles-in-11-brachycephalic-dogs
#17
Davide De Lorenzi, Diana Bertoncello, Chiara Mantovani, Enrico Bottero
OBJECTIVE: To report clinical features, diagnosis, surgical treatment, and outcomes of brachycephalic dogs with nasopharyngeal sialoceles (NPS). STUDY DESIGN: Retrospective case series. ANIMALS: Eleven brachycephalic dogs with NPS. METHODS: Diagnosis of NPS was based on identification of cystic nasopharyngeal masses containing saliva-like mucoid material on retroflexed endoscopy. Biopsies were obtained to support the diagnosis...
April 2018: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/29297558/an-evaluation-of-the-light-output-from-22-contemporary-light-curing-units
#18
Carlos José Soares, Monise de Paula Rodrigues, Laís Rani Sales Oliveira, Stella Sueli Lourenço Braga, Luciana Mendes Barcelos, Gisele Rodrigues da Silva, Marcelo Giannini, Richard Bengt Price
This study measured the radiant power (mW), irradiance (mW/cm2) and emission spectra (mW/cm2/nm) of 22 new, or almost new, light curing units (LCUs): - Alt Lux II, BioLux Standard, Bluephase G2, Curing Light XL 3000, Demetron LC, DX Turbo LED 1200, EC450, EC500, Emitter C, Emitter D, KON-LUX, LED 3M ESPE, Led Lux II, Optilight Color, Optilight Max, Optilux 501, Poly Wireless, Radii cal, Radii plus, TL-01, VALO Cordless. These LCUs were either monowave or multiple peak light emitting diode (LED) units or quartz-tungsten-halogen LCUs used in anterior and posterior teeth...
May 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/29221053/ultra-high-speed-plif-imaging-for-simultaneous-visualization-of-multiple-species-in-turbulent-flames
#19
Zhenkan Wang, Panagiota Stamatoglou, Zheming Li, Marcus Aldén, Mattias Richter
In order to obtain more detailed characteristics and information in highly turbulent flames, for a better understanding of the transient behavior of eddies in such flames, a measurement technique with sufficient temporal resolution is requested. However, the probing of species distributions relevant in combustion (e.g. OH, CH2 O) with ultra-high-speed laser diagnostics still remains a challenge. Nd:YAG clusters commercially available can generate only 4-8 pulses, although with high laser energy. Systems based on a diode-pumped solid-state Nd:YAG laser combined with a dye laser produce only about 100 μJ pulse energy at ultra-high repetition rates (≥50 kHz)...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29131193/frequency-and-timing-stability-of-an-airborne-injection-seeded-nd-yag-laser-system-for-direct-detection-wind-lidar
#20
Christian Lemmerz, Oliver Lux, Oliver Reitebuch, Benjamin Witschas, Christian Wührer
We report on the design and performance of the laser deployed in the airborne demonstrator Doppler wind lidar for the Aeolus mission of the European Space Agency (ESA). The all-solid-state, diode-pumped and frequency-tripled Nd:YAG laser is realized as a master oscillator power amplifier (MOPA) system, generating 60 mJ of single-frequency pulses at 355 nm wavelength, 50 Hz repetition rate and 20 ns pulse duration. For the measurement of the Doppler frequency shift over several accumulated laser shots, the frequency stability of the laser is of crucial importance...
November 10, 2017: Applied Optics
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