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https://www.readbyqxmd.com/read/28220062/anatomical-and-molecular-properties-of-long-descending-propriospinal-neurons-in-mice
#1
Jamie R Flynn, Victoria L Conn, Kieran A Boyle, David I Hughes, Masahiko Watanabe, Tomoko Velasquez, Martyn D Goulding, Robert J Callister, Brett A Graham
Long descending propriospinal neurons (LDPNs) are interneurons that form direct connections between cervical and lumbar spinal circuits. LDPNs are involved in interlimb coordination and are important mediators of functional recovery after spinal cord injury (SCI). Much of what we know about LDPNs comes from a range of species, however, the increased use of transgenic mouse lines to better define neuronal populations calls for a more complete characterisation of LDPNs in mice. In this study, we examined the cell body location, inhibitory neurotransmitter phenotype, developmental provenance, morphology and synaptic inputs of mouse LDPNs throughout the cervical and upper thoracic spinal cord...
2017: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/28219364/the-relationship-between-changes-of-cervical-sagittal-alignment-after-anterior-cervical-discectomy-and-fusion-and-spino-pelvic-sagittal-alignment-under-roussouly-classification-a-four-year-follow-up-study
#2
Dong-Ning Huang, Miao Yu, Nan-Fang Xu, Mai Li, Shao-Bo Wang, Yu Sun, Liang Jiang, Feng Wei, Xiao-Guang Liu, Zhong-Jun Liu
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) is widely used in the treatment of cervical degenerative disease; however, the variation of cervical sagittal alignment changes after ACDF has been rarely explored. The purpose of this study is to determine the relationship between changes of cervical sagittal alignment after ACDF and spino-pelvic sagittal alignment under Roussouly classification. METHODS: A cohort of 133 Chinese cervical spondylotic patients who received ACDF from 2011 to 2012 was recruited...
February 20, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28207663/role-of-ethnicity-in-alignment-compensation-propensity-matched-analysis-of-differential-compensatory-mechanism-recruitment-patterns-for-sagittal-malalignment-in-288-asd-patients-from-japan-korea-and-united-states
#3
Bassel G Diebo, Isaac Gammal, Yoon Ha, Seung Hwan Yoon, Jae Won Chang, Byeongwoo Kim, Morio Matsumoto, Yu Yamato, Daisaku Takeuchi, Naobumi Hosogane, Mitsuru Yagi, Hiroshi Taneichi, Frank Schwab, Virginie Lafage, Christopher Ames
STUDY DESIGN: Retrospective review of adult spinal deformity patients in a multiethnic database. OBJECTIVE: To investigate the role of ethnicity on recruitment of compensatory mechanisms for sagittal spinal deformity. SUMMARY OF BACKGROUND DATA: While the impacts of age, sex, and pelvic morphology on the ability to compensate for sagittal malalignment have been investigated, the role of ethnicity in compensatory mechanism recruitment is poorly understood...
February 15, 2017: Spine
https://www.readbyqxmd.com/read/28158157/successful-long-term-nerve-root-stimulation-for-chronic-neuropathic-pain-a-real-world-single-center-canadian-experience
#4
Adrian B Levine, David A Steven, Andrew G Parrent, Keith W MacDougall
BACKGROUND: Spinal cord stimulation (SCS) is a well-established treatment for chronic neuropathic pain in the lower limbs. However, some patients have pain in distributions that are difficult to target specifically and consistently with SCS. This often involves pain in the groin or upper limbs, or pain limited to a specific dermatome. We hypothesized that dorsal nerve root stimulation (DNRS) would provide similar pain relief for these patients, compared to our results using SCS. OBJECTIVES: In this study we report our experience treating patients with chronic neuropathic pain using SCS and DNRS...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28144582/reliability-and-concurrent-validity-of-postural-asymmetry-measurement-in-adolescent-idiopathic-scoliosis
#5
Ashleigh Prowse, Berit Aslaksen, Marie Kierkegaard, James Furness, Paul Gerdhem, Allan Abbott
AIM: To investigate the reliability and concurrent validity of the Baseline(®) Body Level/Scoliosis meter for adolescent idiopathic scoliosis postural assessment in three anatomical planes. METHODS: This is an observational reliability and concurrent validity study of adolescent referrals to the Orthopaedic department for scoliosis screening at Karolinska University Hospital, Stockholm, Sweden between March-May 2012. A total of 31 adolescents with idiopathic scoliosis (13...
January 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28143506/utilization-of-ct-scanning-associated-with-complex-spine-surgery
#6
Vikas V Patel, Gunnar B J Andersson, Steven R Garfin, Donald L Resnick, Jon E Block
BACKGROUND: Due to the risk associated with exposure to ionizing radiation, there is an urgent need to identify areas of CT scanning overutilization. While increased use of diagnostic spinal imaging has been documented, no previous research has estimated the magnitude of follow-up imaging used to evaluate the postoperative spine. METHODS: This retrospective cohort study quantifies the association between spinal surgery and CT utilization. An insurance database (Humana, Inc...
January 31, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28139188/sagittal-plane-analysis-of-the-spine-and-pelvis-in-degenerative-lumbar-scoliosis
#7
Fei Han, Li Weishi, Sun Zhuoran, Ma Qingwei, Chen Zhongqiang
BACKGROUND: Previous studies have reported the normative values of pelvic sagittal parameters, but no study has analyzed the sagittal spino-pelvic alignment in degenerative lumbar scoliosis (DLS) and its role in the pathogenesis. METHODS: Retrospective analysis was applied to 104 patients with DLS, together with 100 cases of asymptomatic young adults as a control group and another control group consisting of 145 cases with cervical spondylosis. The coronal and sagittal parameters were measured on the anteroposterior and lateral radiograph of the whole spine in the DLS group as well as in the two control groups...
January 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28138167/congenital-abnormalities-of-the-ribs-evaluation-with-multidetector-computed-tomography
#8
Ramazan Davran, Hanifi Bayarogullari, Nesrin Atci, Alperen Kayali, Fatma Ozturk, Gulen Burakgazi
OBJECTIVE: To evaluate congenital abnormalities of ribs using multidetector computed tomography. METHODS: The retrospective study was conducted at Mustafa Kemal University Research Hospital, Hatay, Turkey and comprised data of patients aged 1-45 years who attended the Radiology Department for computed tomography of the thorax between January 2010 and July 2013. Multiplanar reconstructions, maximum intensity projections, and 3-dimensional images were acquired to investigate numerical and structural abnormalities of the ribs of the patients who underwent multidetector computed tomography for a variety of indications...
February 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28128704/cervical-lordotic-alignment-following-posterior-spinal-fusion-for-adolescent-idiopathic-scoliosis-reciprocal-changes-and-risk-factors-for-malalignment
#9
Kazunori Hayashi, Hiromitsu Toyoda, Hidetomi Terai, Akinobu Suzuki, Masatoshi Hoshino, Koji Tamai, Shoichiro Ohyama, Hiroaki Nakamura
OBJECTIVE Numerous reports have been published on the effectiveness and safety of correction of the coronal Cobb angle and thoracolumbar sagittal alignment in patients with adolescent idiopathic scoliosis (AIS). Suboptimal sagittal alignment, such as decreased thoracic kyphosis (TK), after corrective surgery, is a possible cause of lumbar or cervical spinal degeneration and junctional malalignment; however, few reports are available on reciprocal changes outside of the fused segments, such as the cervical lordotic angle (CLA)...
January 27, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28127750/standing-sagittal-alignment-of-the-whole-axial-skeleton-with-reference-to-the-gravity-line-in-humans
#10
Kazuhiro Hasegawa, Masashi Okamoto, Shun Hatsushikano, Haruka Shimoda, Masatoshi Ono, Takao Homma, Kei Watanabe
Human beings stand upright with the chain of balance beginning at the feet, progressing to the lower limbs (ankles, knees, hip joints, pelvis), each of the spinal segments, and then ending at the cranium to achieve horizontal gaze and balance using minimum muscle activity. The details of the alignment and balance of the chain, however, are not clearly understood, due to the lack of information regarding the three-dimensional (3D) orientation of all bony elements in relation to the gravity line (GL). We performed a clinical study to clarify the standing sagittal alignment of whole axial skeletons in reference to the GL using the EOS slot-scanning 3D X-ray imaging system with simultaneous force plate measurement in a healthy human population...
January 27, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28119879/influence-of-the-proprioceptive-neuromuscular-facilitation-exercise-programs-on-idiopathic-scoliosis-patient-in-the-early-20s-in-terms-of-curves-and-balancing-abilities-single-case-study
#11
Byung-Ki Lee
The purpose of this study was to determine the influence of the proprioceptive neuromuscular facilitation (PNF) exercise programs for idiopathic scoliosis with a female patient in the early 20s in terms of her spinal curve and balancing abilities. The study subject was selected among 21-year-old female college students. There were no particular activities that the subject could not perform, but patient complained of difficulty in maintaining the standing position for a prolonged time. Patient chest X-ray results showed S-shaped curves tilted towards the left or right in the lumbar spine, thoracic spine, and cervical spine areas...
December 2016: Journal of Exercise Rehabilitation
https://www.readbyqxmd.com/read/28110361/the-impact-of-routine-whole-spine-mri-screening-in-the-evaluation-of-spinal-degenerative-diseases
#12
Rishi Mugesh Kanna, Younis Kamal, Anupama Mahesh, Prakash Venugopal, Ajoy Prasad Shetty, S Rajasekaran
PURPOSE: Magnetic resonance imaging (MRI) of the spine is a sensitive investigation, which not only provides detailed images of the spinal column but also adjacent spinal regions and para-vertebral organ systems. Such incidental findings (IF) can be asymptomatic but significant. The efficacy of whole spine T2 sagittal screening in providing additional information has been demonstrated in several spinal diseases but its routine use in patients with spinal degenerative diseases has not been studied...
January 21, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28106525/open-and-endovascular-treatment-of-spinal-dural-arteriovenous-fistulas-a-10-year-experience
#13
Matthew J Koch, Christopher J Stapleton, Pankaj K Agarwalla, Collin Torok, John H Shin, Jean-Valery Coumans, Lawrence F Borges, Christopher S Ogilvy, James D Rabinov, Aman B Patel
OBJECTIVE Vascular malformations of the spine represent rare clinical entities with profound neurological implications. Previously reported studies on management strategies for spinal dural arteriovenous fistulas (sDAVFs) appeared before the advent of modern liquid embolic agents. Authors of the present study review their institutional experience with endovascularly and surgically treated sDAVFs. METHODS The authors performed a retrospective, observational, single-center case series on sDAVFs treated with endovascular embolization, microsurgical occlusion, or both between 2004 and 2013...
January 20, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28072687/the-negative-chronotropic-effect-during-lumbar-spine-surgery-a-systemic-review-and-aggregation-of-an-emerging-model-of-spinal-cardiac-reflex
#14
REVIEW
Tumul Chowdhury, Bernhard Schaller
BACKGROUND: Hemodynamic perturbations in spine surgeries are predominantly reported in cervical and thoracic level procedures. The literature related to negative cardiovascular changes (decrease of heart rate and blood pressure) in lumbar spine procedures is still scarce and only highlighted in few case reports/letters until now. METHODS: With the help of a systematic literature review with predefined criteria, we, therefore, examined and synthesized here the probable underlying common cause of these hemodynamic disturbances in lumbar spine surgeries...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28068278/cervical-spondylitis-and-epidural-abscess-caused-by-brucellosis-a-case-report-and-literature-review
#15
Hatice Reşorlu, Suzan Saçar, Beşir Şahin Inceer, Ayla Akbal, Ferhat Gökmen, Coskun Zateri, Yilmaz Savaş
Brucellosis is a zoonotic disease widely seen in endemic regions and that can lead to systemic involvement. The musculoskeletal system is frequently affected, and the disease can exhibit clinical involvements such as arthritis, spondylitis, spondylodiscitis, osteomyelitis, tenosynovitis and bursitis. Spondylitis and spondylodiscitis, common complications of brucellosis, predominantly affect the lumbar and thoracic vertebrae. Epidural abscess may occur as a rare complication of spondylitis. Spinal brucellosis and development of epidural abscess in the cervical region are rare...
December 1, 2016: Folia Medica
https://www.readbyqxmd.com/read/28068167/vehicle-exposure-and-spinal-musculature-fatigue-in-military-warfighters-a-meta-analysis
#16
REVIEW
Roger O Kollock, Kenneth E Games, Alan E Wilson, JoEllen M Sefton
CONTEXT:  Spinal musculature fatigue from vehicle exposure may place warfighters at risk for spinal injuries and pain. Research on the relationship between vehicle exposure and spinal musculature fatigue is conflicting. A better understanding of the effect of military duty on musculoskeletal function is needed before sports medicine teams can develop injury-prevention programs. OBJECTIVE:  To determine if the literature supports a definite effect of vehicle exposure on spinal musculature fatigue...
November 2016: Journal of Athletic Training
https://www.readbyqxmd.com/read/28065817/reproducibility-of-sagittal-radiographic-parameters-in-adolescent-idiopathic-scoliosis-a-guide-to-reference-values-using-serial-imaging
#17
Hwee Weng Dennis Hey, Gordon Chengyuan Wong, Chloe Chan Xiaoyun, Leok-Lim Lau, Naresh Kumar, Joseph Shantakumar Thambiah, John Nathaniel Ruiz, Ka-Po Gabriel Liu, Hee-Kit Wong
BACKGROUND CONTEXT: Knowledge of sagittal radiographical parameters in AIS patients has not yet caught up with our understanding of their roles in patients with adult spinal deformity. It is likely that more emphasis will be placed in restoring sagittal parameters for AIS patients in the future. Therefore we need to understand how these parameters may vary in AIS to facilitate management plans. PURPOSE: To determine the reproducibility of sagittal spinal parameters on lateral film radiographs in patients with AIS...
January 5, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28059798/sporadic-cases-with-novel-mutations-and-pedigree-in-hereditary-leukoencephalopathy-with-axonal-spheroids
#18
Liyong Wu, Jia Liu, Longze Sha, Xianling Wang, Jieying Li, Jing Dong, Jianping Jia
Hereditary diffuse leukoencephalopathy with spheroids (HDLS) is an autosomal dominant hereditary disease, featured by cerebral white matter degeneration with demyelination and axonal spheroids. We collected three gene-confirmed HDLS cases in our neurodegenerative clinic. Two HDLS cases were sporadic with novel mutations, while another case had a family history with previously described mutations. All three cases suffered memory problems with white matter lesions and pyramid signs. No obvious clinical differences were observed between sporadic and familial HDLS cases...
December 3, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28050972/registration-of-mri-to-intraoperative-radiographs-for-target-localization-in-spinal-interventions
#19
T De Silva, A Uneri, M D Ketcha, S Reaungamornrat, J Goerres, M W Jacobson, S Vogt, G Kleinszig, A J Khanna, J-P Wolinsky, J H Siewerdsen
Decision support to assist in target vertebra localization could provide a useful aid to safe and effective spine surgery. Previous solutions have shown 3D-2D registration of preoperative CT to intraoperative radiographs to reliably annotate vertebral labels for assistance during level localization. We present an algorithm (referred to as MR-LevelCheck) to perform 3D-2D registration based on a preoperative MRI to accommodate the increasingly common clinical scenario in which MRI is used instead of CT for preoperative planning...
January 4, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28048300/th-cd-206-10-clinical-application-of-the-mind-demons-algorithm-for-symmetric-diffeomorphic-deformable-mr-to-ct-image-registration-in-spinal-interventions
#20
S Reaungamornrat, T De Silva, A Uneri, J Wolinsky, A Khanna, G Kleinszig, S Vogt, J Prince, J Siewerdsen
PURPOSE: Accurate intraoperative localization of target anatomy (e.g., tumors and vertebral levels) and critical structures (e.g., nerves and vessels) is essential to safe, effective surgery. Preoperative CT/MR images can be used to identify such vital anatomy in intraoperative images through multimodality deformable registration. We proposed a deformable registration method to align preoperative MR to intraoperative CT using modality-independent neighborhood descriptors (MIND) and a Huber metric for robust registration...
June 2016: Medical Physics
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