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Ankle brachial index in ckd

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https://www.readbyqxmd.com/read/27880852/clinical-characteristics-and-outcomes-of-patients-with-high-ankle-brachial-index-from-the-impact-abi-study
#1
Hitoshi Nishimura, Takashi Miura, Masatoshi Minamisawa, Yasushi Ueki, Naoyuki Abe, Naoto Hashizume, Tomoaki Mochidome, Mikiko Harada, Kunihiko Shimizu, Wataru Shoin, Koji Yoshie, Yasutaka Oguchi, Soichiro Ebisawa, Hirohiko Motoki, Atsushi Izawa, Jun Koyama, Uichi Ikeda, Koichiro Kuwahara
BACKGROUND: Reduced ankle-brachial index (ABI) is a predictor of cardiovascular events. However, the significance of high ABI remains poorly understood. This study aimed to assess the characteristics and outcomes of patients with high ABI. METHODS: The IMPACT-ABI study was a retrospective cohort study that enrolled and examined ABI in 3,131 patients hospitalized for cardiovascular disease between January 2005 and December 2012. From this cohort, 2,419 patients were identified and stratified into two groups: high ABI (> 1...
2016: PloS One
https://www.readbyqxmd.com/read/27754076/os-18-08-optimal-blood-pressure-goal-for-the-elderly-chinese-the-findings-from-the-northern-shanghai-study
#2
Jiadela Teliewubai, Yu-Yan Lv, Shi-Kai Yu, Bin Bai, Chen Chi, Kai Wang, Yi-Wu Zhou, Jing Xiong, Yi Zhang, Ya-Wei Xu
OBJECTIVE: The Eighth Joint National Committee Panel recommended novel blood pressure (BP) goals for individuals with hypertension, which is still under debate. We therefore assessed patients' target organ damages in controlled hypertensives defined by the Seventh or Eighth Joint National Committee thresholds (JNC7 and JNC8) in a community-based elderly Chinese population, in order to find the optimal BP goal for the elderly Chinese. DESIGN AND METHOD: 1599 community-based elderly participants (age > 65 years old) were recruited in the northern Shanghai...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27695492/subclinical-cardiovascular-disease-markers-and-vitamin-d-deficiency-in-non-dialysis-chronic-kidney-disease-patients
#3
Cristina Căpuşa, Gabriel Stefan, Simona Stancu, Andrea Ilyes, Nicoleta Dorobanţu, Gabriel Mircescu
INTRODUCTION: Since 25-hydroxyvitamin D (25(OH)D) deficiency has been linked to an increased risk for cardiovascular disease (CVD) in the hemodialysis population, we aimed to determine the relationship between serum 25(OH)D level and markers of subclinical CVD in non-dialysis chronic kidney disease (CKD) patients. MATERIAL AND METHODS: This cross-sectional, single-center study prospectively enrolled 87 clinically stable CKD patients (median age: 61 (57-66) years, 51% male, median estimated glomerular filtration rate (eGFR): 32 (27-37) ml/min)...
October 1, 2016: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/27642997/os-18-08-optimal-blood-pressure-goal-for-the-elderly-chinese-the-findings-from-the-northern-shanghai-study
#4
Jiadela Teliewubai, Yu-Yan Lv, Shi-Kai Yu, Bin Bai, Chen Chi, Kai Wang, Yi-Wu Zhou, Jing Xiong, Yi Zhang, Ya-Wei Xu
OBJECTIVE: The Eighth Joint National Committee Panel recommended novel blood pressure (BP) goals for individuals with hypertension, which is still under debate. We therefore assessed patients' target organ damages in controlled hypertensives defined by the Seventh or Eighth Joint National Committee thresholds (JNC7 and JNC8) in a community-based elderly Chinese population, in order to find the optimal BP goal for the elderly Chinese. DESIGN AND METHOD: 1599 community-based elderly participants (age > 65 years old) were recruited in the northern Shanghai...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27615597/circulating-angiotensin-converting-enzyme-2-activity-as-a-biomarker-of-silent-atherosclerosis-in-patients-with-chronic-kidney-disease
#5
Lidia Anguiano, Marta Riera, Julio Pascual, José Manuel Valdivielso, Clara Barrios, Angels Betriu, Sergi Clotet, Sergi Mojal, Elvira Fernández, María José Soler
BACKGROUND AND AIMS: Circulating Angiotensin Converting Enzyme 2 (ACE2) activity in chronic kidney disease (CKD) patients without previous history of cardiovascular disease (CVD) has been associated with classical risk factors (older age, diabetes and male gender). Furthermore, silent atherosclerosis has been described as a pathological link between CKD and CVD. We analyzed baseline ACE2 activity in non-dialysis CKD stages 3-5 (CKD3-5) patients as a biomarker of renal progression, silent atherosclerosis and CV events after 2 years of follow-up...
October 2016: Atherosclerosis
https://www.readbyqxmd.com/read/27565838/aspirin-and-renal-insufficiency-progression-in-patients-with-atrial-fibrillation-and-chronic-kidney-disease
#6
Daniele Pastori, Pasquale Pignatelli, Francesco Perticone, Angela Sciacqua, Roberto Carnevale, Alessio Farcomeni, Stefania Basili, Gino R Corazza, Giovanni Davì, Gregory Y H Lip, Francesco Violi
BACKGROUND: In experimental models, thromboxane (Tx)A2 reduced renal perfusion and accelerated renal failure. The aim of the study was to investigate the association between the use of aspirin, which inhibits TxA2 production, and the incidence of an estimated Glomerular Filtration Rate (eGFR) <60 and <45ml/min/1.73m(2) in patients with atrial fibrillation (AF) and chronic kidney disease (CKD). METHODS: Prospective multicentre observational cohort study including 800 anticoagulated AF patients; CKD was defined as an eGFR <90ml/min/1...
November 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27247339/ankle-brachial-index-and-subsequent-cardiovascular-disease-risk-in-patients-with-chronic-kidney-disease
#7
Jing Chen, Emile R Mohler, Pranav S Garimella, L Lee Hamm, Dawei Xie, Stephen Kimmel, Raymond R Townsend, Matthew Budoff, Qiang Pan, Lisa Nessel, Susan Steigerwalt, Jackson T Wright, Jiang He
BACKGROUND: The clinical implications of ankle-brachial index (ABI) cutpoints are not well defined in patients with chronic kidney disease (CKD) despite increased prevalence of high ABI attributed to arterial stiffness. We examined the relationship of ABI with cardiovascular disease (CVD) and all-cause mortality among CKD patients. METHODS AND RESULTS: Three thousand six hundred twenty-seven participants without clinical peripheral artery disease (PAD) at baseline from the Chronic Renal Insufficiency Cohort Study were included...
June 2016: Journal of the American Heart Association
https://www.readbyqxmd.com/read/27216577/the-associations-between-peripheral-artery-disease-and-physical-outcome-measures-in-men-and-women-with-chronic-kidney-disease
#8
Grace J Wang, Pamela A Shaw, Raymond R Townsend, Amanda H Anderson, Dawei Xie, Xue Wang, Lisa C Nessel, Emile R Mohler, Stephen M Sozio, Bernard G Jaar, Jing Chen, Jackson Wright, Jonathan J Taliercio, Akinlolu Ojo, Ana C Ricardo, Eva Lustigova, Ronald M Fairman, Harold I Feldman, Bonnie Ky
BACKGROUND: Peripheral artery disease (PAD) is highly prevalent and associated with significant morbidity and mortality, but sex-based differences are incompletely understood. We sought to define the associations between PAD and physical outcome measures and to determine if these associations differed by sex in the Chronic Renal Insufficiency Cohort. METHODS: Among 3,543 participants, we assessed the cross-sectional relationship between PAD severity defined by ankle-brachial index; and (1) physical activity (metabolic equivalent [MET]-hr/wk), (2) walking pace (slow versus medium and/or fast), and (3) physical function (12-item Short Form Health Survey [SF-12]) at baseline...
August 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/27190385/factors-influencing-pathological-ankle-brachial-index-values-along-the-chronic-kidney-disease-spectrum-the-nefrona-study
#9
David Arroyo, Angels Betriu, Joan Valls, Jose L Gorriz, Vicente Pallares, Maria Abajo, Marta Gracia, Jose Manuel Valdivielso, Elvira Fernandez
BACKGROUND: The ankle-brachial index (ABI) is widely used to diagnose subclinical peripheral artery disease (PAD) in the general population, but data assessing its prevalence and related factors in different chronic kidney disease (CKD) stages are scarce. The aim of this study is to evaluate the prevalence and associated factors of pathological ABI values in CKD patients. METHODS: NEFRONA is a multicentre prospective project that included 2445 CKD patients from 81 centres and 559 non-CKD subjects from 9 primary care centres across Spain...
May 4, 2016: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/27087869/distribution-of-ankle-brachial-index-among-inpatients-with-cardiovascular-disease-analysis-using-the-kumamoto-university-hospital-medical-database
#10
Seiji Hokimoto, Hirofumi Soejima, Sunao Kojima, Koichi Kaikita, Megumi Yamamuro, Yasuhiro Izumiya, Kenichi Tsujita, Eiichiro Yamamoto, Tomoko Tanaka, Koichi Sugamura, Yuichiro Arima, Kenji Sakamoto, Tomonori Akasaka, Noriaki Tabata, Daisuke Sueta, Izuru Miyoshi, Makiko Usami, Hisao Ogawa
OBJECTIVE: To describe the distribution of ankle-brachial index (ABI) among Japanese cardiovascular inpatients and to explore risk factors of peripheral arterial disease (PAD) associated with ABI ≤0.9. MATERIALS AND METHODS: This study was a retrospective analysis using clinical record databases of patients with cardiovascular disease admitted to the Department of Cardiovascular Medicine, Kumamoto University Hospital between 2007 and 2014. RESULTS: Of 3639 patients included in the analysis, male patients accounted for 62...
2016: Annals of Vascular Diseases
https://www.readbyqxmd.com/read/27044887/randomised-intervention-study-to-assess-the-prevalence-of-subclinical-vascular-disease-and-hidden-kidney-disease-and-its-impact-on-morbidity-and-mortality-the-ilervas-project
#11
Àngels Betriu, Cristina Farràs, María Abajo, Montserrat Martinez-Alonso, David Arroyo, Ferran Barbé, Miquel Buti, Albert Lecube, Manuel Portero, Francisco Purroy, Gerard Torres, José Manuel Valdivielso, Elvira Fernández
BACKGROUND AND OBJECTIVES: Chronic kidney disease (CKD) and atherosclerosis are 2 interrelated diseases that increase the risk of cardiovascular morbidity and mortality. The objectives of the ILERVAS project are: 1) to determine the prevalence of subclinical arterial disease and hidden kidney disease; 2) to assess the impact of early diagnosis of both diseases on cardiovascular morbidity and mortality and also on the progression of CKD; 3) to have a platform of data and biological samples...
July 2016: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/26908866/sex-differences-in-the-incidence-of-peripheral-artery-disease-in-the-chronic-renal-insufficiency-cohort
#12
Grace J Wang, Pamela A Shaw, Raymond R Townsend, Amanda H Anderson, Dawei Xie, Xue Wang, Lisa C Nessel, Emile R Mohler, Stephen M Sozio, Bernard G Jaar, Jing Chen, Jackson Wright, Jonathan J Taliercio, Akinlolu Ojo, Ana C Ricardo, Eva Lustigova, Ronald M Fairman, Harold I Feldman, Bonnie Ky
BACKGROUND: To define how the incidence of peripheral artery disease (PAD) in chronic kidney disease differs according to sex and age. METHODS AND RESULTS: The Chronic Renal Insufficiency Cohort (CRIC) is a multicenter, prospective cohort study of chronic kidney disease participants. Fine and Gray methods were used to determine the cumulative incidence of PAD, defined by an ankle brachial index <0.90 or a confirmed PAD event, with death as a competing event. Adjusted subdistribution hazard ratios from the Fine and Gray model determined the risk of PAD according to sex...
February 2016: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/26845338/serum-vascular-adhesion-protein-1-predicts-end-stage-renal-disease-in-patients-with-type-2-diabetes
#13
Hung-Yuan Li, Hung-An Lin, Feng-Jung Nien, Vin-Cent Wu, Yi-Der Jiang, Tien-Jyun Chang, Hsien-Li Kao, Mao-Shin Lin, Jung-Nan Wei, Cheng-Hsin Lin, Shyang-Rong Shih, Chi-Sheng Hung, Lee-Ming Chuang
BACKGROUND: Diabetes is the leading cause of end-stage renal disease (ESRD) worldwide. Vascular adhesion protein-1 (VAP-1) participates in inflammation and catalyzes the deamination of primary amines into aldehydes, hydrogen peroxide, and ammonia, both of which are involved in the pathogenesis of diabetic complications. We have shown that serum VAP-1 is higher in patients with diabetes and in patients with chronic kidney disease (CKD), and can predict cardiovascular mortality in subjects with diabetes...
2016: PloS One
https://www.readbyqxmd.com/read/26841805/baseline-characterization-of-japanese-peripheral-arterial-disease-patients%C3%A3-analysis-of-surveillance-of-cardiovascular-events-in-antiplatelet-treated-arteriosclerosis-obliterans-patients-in-japan-season
#14
MULTICENTER STUDY
Yukihito Higashi, Tetsuro Miyata, Hiroshi Shigematsu, Hideki Origasa, Masatoshi Fujita, Hiroshi Matsuo, Hiroaki Naritomi, Hiroaki Matsuda, Masahide Nakajima
BACKGROUND: Despite mounting evidence of increased cardiovascular events in patients with peripheral arterial disease (PAD), the overall incidence of cardiovascular events in PAD patients has not been fully clarified in Japan. The prospective Surveillance of cardiovascular Events in Antiplatelet-treated arterioSclerosis Obliterans patients in JapaN (SEASON) is a prospective observational multicenter study and here we report the baseline clinical characteristics, including atherosclerosis risk factor prevalence, in PAD patients treated with antiplatelet agents...
2016: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/26682964/traditional-and-non-traditional-risk-factors-for-incident-peripheral-arterial-disease-among-patients-with-chronic-kidney-disease
#15
Jing Chen, Emile R Mohler, Dawei Xie, Michael Shlipak, Raymond R Townsend, Lawrence J Appel, Akinlolu Ojo, Martin Schreiber, Lisa Nessel, Xiaoming Zhang, Dominic Raj, Louise Strauss, Claudia M Lora, Mahboob Rahman, L Lee Hamm, Jiang He
BACKGROUND: The risk of peripheral arterial disease (PAD) is higher in patients with chronic kidney disease (CKD) compared with those without. However, reasons for this increased risk are not fully understood. METHODS: We studied risk factors for incident PAD among 3169 participants in the Chronic Renal Insufficiency Cohort (CRIC) Study. Patients with CKD aged 21-74 years were recruited between 2003 and 2008 and followed for a median of 6.3 years. Incident PAD was defined as a new onset ankle-brachial index (ABI) of <0...
July 2016: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/26559609/association-of-body-mass-index-and-left-ventricular-mass-index-with-abnormally-low-and-high-ankle-brachial-indices-in-chronic-kidney-disease
#16
Szu-Chia Chen, Wen-Hsien Lee, Po-Chao Hsu, Jiun-Chi Huang, Chee-Siong Lee, Tsung-Hsien Lin, Wen-Chol Voon, Wen-Ter Lai, Sheng-Hsiung Sheu, Ho-Ming Su
Obesity, left ventricular hypertrophy (LVH) and peripheral artery disease are frequently noted in patients with chronic kidney disease (CKD), thereby suggesting a close and causal relationship among them. This study was designed to assess whether the combination of an increased body mass index (BMI) and left ventricular mass index (LVMI) are independently associated with abnormally low and high ABI in patients with CKD stages 3-5. A total of 566 patients were included in the study and were classified into four groups according to sex-specific median BMIs and LVMIs...
March 2016: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/26455728/lower-limb-ischaemia-in-patients-with-diabetic-foot-ulcers-and-gangrene-recognition-anatomic-patterns-and-revascularization-strategies
#17
Joseph L Mills
The confluence of several chronic conditions--in particular ageing, peripheral artery disease, diabetes, and chronic kidney disease--has created a global wave of lower limbs at risk for major amputation. While frequently asymptomatic or not lifestyle limiting, at least 1% of the population has peripheral artery disease of sufficient severity to be limb threatening. To avoid the critical error of failing to diagnose ischaemia, all patients with diabetic foot ulcers and gangrene should routinely undergo physiologic evaluation of foot perfusion...
January 2016: Diabetes/metabolism Research and Reviews
https://www.readbyqxmd.com/read/26356694/metabolic-syndrome-associated-risk-factors-and-high-sensitivity-c-reactive-protein-independently-predict-arterial-stiffness-in-9903-subjects-with-and-without-chronic-kidney-disease
#18
Sung-Sheng Tsai, Yu-Sheng Lin, Chia-Pin Lin, Jawl-Shan Hwang, Lung-Sheng Wu, Pao-Hsien Chu
Metabolic syndrome (MS), high-sensitivity C-reactive protein (hs-CRP), and chronic kidney disease (CKD) are related to cardiovascular diseases. Although MS is common in CKD subjects, the contribution of MS-associated risk factors and hs-CRP to arterial stiffness in CKD has not been well studied.In this cross-sectional cohort study, we enrolled 9903 subjects who underwent brachial-ankle pulse wave velocity (baPWV) measurements from our database of Health Care Center. CKD was defined as an estimated glomerular filtration rate (eGFR) <60 mL/min/1...
September 2015: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26354563/prevalence-of-peripheral-arterial-disease-diagnosed-by-ankle-brachial-index-among-chronic-kidney-disease-patients-in-a-tertiary-care-unit
#19
Saeed Laghari, Kifayat Ullah, Imtiaz Masroor, Ghias Butt, Farina Kifayat
The objective of this study is to determine the prevalence of peripheral vascular disease (PVD) in patients with chronic kidney disease (CKD). Seventy-two patients with CKD stage 3 or above were included in this study. Blood samples were taken from each patient to determine complete blood counts, serum albumin, electrolytes, lipid profile and blood sugar random/fasting. The glomerular filtration rate (GFR) was estimated with the Cockcroft-Gault formula. The ankle-brachial index (ABI) was determined to identify the presence of PVD...
September 2015: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/26181592/the-addition-of-vascular-calcification-scores-to-traditional-risk-factors-improves-cardiovascular-risk-assessment-in-patients-with-chronic-kidney-disease
#20
Sophie Liabeuf, Lucie Desjardins, Momar Diouf, Mohamed Temmar, Cédric Renard, Gabriel Choukroun, Ziad A Massy
BACKGROUND: Although a variety of non-invasive methods for measuring cardiovascular (CV) risk (such as carotid intima media thickness, pulse wave velocity (PWV), coronary artery and aortic calcification scores (measured either by CT scan or X-ray) and the ankle brachial index (ABI)) have been evaluated separately in chronic kidney disease (CKD) cohorts, few studies have evaluated these methods simultaneously. Here, we looked at whether the addition of non-invasive methods to traditional risk factors (TRFs) improves prediction of the CV risk in patients at different CKD stages...
2015: PloS One
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