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https://www.readbyqxmd.com/read/29444463/a-comparative-study-on-oxidative-stress-response-in-the-hepatopancreas-and-midgut-of-the-white-shrimp-litopenaeus-vannamei-under-gradual-changes-to-low-or-high-ph-environment
#1
Si-Yin Han, Meng-Qiang Wang, Bao-Jie Wang, Mei Liu, Ke-Yong Jiang, Lei Wang
White shrimp Litopenaeus vannamei were reared under conditions of gradual changes to a low pH (gradual-low pH, 6.65-8.20) or a high pH (gradual-high pH, 8.20-9.81) versus a normal pH environment (8.14-8.31) during a 28-day period. Survival of shrimp, and ROS production, antioxidant responses and oxidative damage in the hepatopancreas and midgut were investigated. Consequently, shrimp enhanced MnSOD, GPx, and Hsp70 transcripts as early defense mechanism in the hepatopancreas and midgut to scavenge excessive ROS during short-term (≤7 d) gradual-low and high pH stress...
February 11, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29444412/heart-rate-variability-responses-to-acute-and-repeated-post-exercise-sauna-in-trained-cyclists
#2
Anthony S Leicht, Aaron Halliday, Wade H Sinclair, Shaun D'Auria, Martin Buchheit, Glen P Kenny, Jamie Stanley
Short- to medium-term (i.e. 4-14 days) heating protocols induce physiological adaptations including improved cardiac autonomic modulations, as assessed using heart rate variability, which may contribute to greater exercise performance. Whether similar cardiac autonomic changes occur during an intense heating protocol (sauna) reported to increase plasma volume in athletes remains to be confirmed. This study examined the changes in heart rate and its variability during a single, extreme heat (sauna) exposure and repeated exposures in athletes...
February 14, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29444319/beneficial-effects-of-water-soluble-chestnut-castanea-sativa-mill-tannin-extract-on-chicken-small-intestinal-epithelial-cell-culture
#3
M Brus, L Gradišnik, M Trapecar, D Škorjanc, R Frangež
Feed and water supplementation with powdered hydrolyzable tannins from chestnut represents a valuable alternative strategy to antibiotics in animal nutrition. In this study, we evaluated the effects and safety of a water-soluble form of chestnut tannin (WST) in an in vitro model of chicken small intestinal epithelial cells (CSIEC). A chicken cell culture was established, and WST in concentrations of 0.025, 0.05, 0.1, and 0.2% were tested for cytotoxicity, cell proliferation, metabolic activity, production of reactive oxygen species, intracellular antioxidative potential, genotoxicity, and influence on the epithelia cell cycle...
February 12, 2018: Poultry Science
https://www.readbyqxmd.com/read/29444214/minimally-invasive-esophagectomy-may-contribute-to-long-term-respiratory-function-after-esophagectomy-for-esophageal-cancer
#4
K Kosumi, N Yoshida, K Okadome, T Eto, D Kuroda, M Ohuchi, Y Kiyozumi, K Nakamura, D Izumi, R Tokunaga, K Harada, K Mima, H Sawayama, T Ishimoto, M Iwatsuki, Y Baba, Y Miyamoto, M Watanabe, H Baba
Evidence suggests that minimally invasive esophagectomy has several advantages with regard to short-term outcomes, compared to open esophagectomy in esophageal cancer patients. However, the impact of minimally invasive esophagectomy on long-term respiratory function remains unknown. The objective of this study is to assess the association between use of the minimally invasive esophagectomy and long-term respiratory dysfunction in esophageal cancer patients after esophagectomy. This retrospective single institution study using prospectively collected data included 87 consecutive esophageal cancer patients who had undergone esophagectomy...
February 9, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29444151/predicting-1-year-mortality-after-hospitalization-for-community-acquired-pneumonia
#5
Ane Uranga, Jose M Quintana, Urko Aguirre, Amaia Artaraz, Rosa Diez, Silvia Pascual, Aitor Ballaz, Pedro P España
BACKGROUND: Community-acquired pneumonia (CAP) is a major public health problem with high short- and long-term mortality. The main aim of this study was to develop and validate a specific prognostic index for one-year mortality in patients admitted for CAP. METHODS: This was an observational, prospective study of adults aged ≥18 years admitted to Galdakao-Usansolo Hospital (Bizkaia, Spain) from January 2001 to July 2009 with a diagnosis of CAP surviving the first 15 days...
2018: PloS One
https://www.readbyqxmd.com/read/29444100/super-ranging-a-new-ranging-strategy-in-european-badgers
#6
Aoibheann Gaughran, David J Kelly, Teresa MacWhite, Enda Mullen, Peter Maher, Margaret Good, Nicola M Marples
We monitored the ranging of a wild European badger (Meles meles) population over 7 years using GPS tracking collars. Badger range sizes varied seasonally and reached their maximum in June, July and August. We analysed the summer ranging behaviour, using 83 home range estimates from 48 individuals over 6974 collar-nights. We found that while most adult badgers (males and females) remained within their own traditional social group boundaries, several male badgers (on average 22%) regularly ranged beyond these traditional boundaries...
2018: PloS One
https://www.readbyqxmd.com/read/29443766/meta-analysis-study-comparing-percutaneous-coronary-intervention-drug-eluting-stent-versus-coronary-artery-bypass-surgery-of-unprotected-left-main-coronary-artery-disease-clinical-outcomes-during-short-term-versus-long-term-1-year-follow-up
#7
Waleed E Ali, Satyanarayana R Vaidya, Sylvester U Ejeh, Kingsley U Okoroafor
BACKGROUND: Results on the safety and long-term efficacy of drug-eluting stent placement in unprotected left main coronary artery disease (ULMCAD) compared with those of coronary artery bypass surgery (CABG) remain inconsistent across randomized clinical trials and recent meta-analysis studies. We aimed to compare the clinical outcomes and safety over short- and long-term follow-ups by conducting a meta-analysis of large pooled data from randomized controlled trials and up-to-date observational studies...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29443392/spatial-aspects-of-oncogenic-signaling-determine-response-to-combination-therapy-in-slice-explants-from-kras-driven-lung-tumors
#8
Katja Närhi, Ashwini S Nagaraj, Elina Parri, Riku Turkki, Petra W van Duijn, Annabrita Hemmes, Jenni Lahtela, Virva Uotinen, Mikko I Mäyränpää, Kaisa Salmenkivi, Jari Räsänen, Nina Linder, Jan Trapman, Antti Rannikko, Olli Kallioniemi, Taija Af Hällström, Johan Lundin, Wolfgang Sommergruber, Simon Anders, Emmy W Verschuren
A key question in precision medicine is how functional heterogeneity in solid tumors informs therapeutic sensitivity. We demonstrate that spatial characteristics of oncogenic signaling and therapy response can be modeled in precision-cut slices from Kras-driven non-small cell lung cancer (NSCLC) of varying histopathologies. Unexpectedly, profiling of in situ tumors demonstrates that signaling stratifies mostly according to histopathology, showing enhanced AKT and SRC activity in adenosquamous carcinoma (ASC), and MAPK activity in adenocarcinoma (AC)...
February 14, 2018: Journal of Pathology
https://www.readbyqxmd.com/read/29443094/in-vivo-imaging-of-muscle-tendon-morphogenesis-in-drosophila-pupae
#9
Sandra B Lemke, Frank Schnorrer
Muscles together with tendons and the skeleton enable animals including humans to move their body parts. Muscle morphogenesis is highly conserved from animals to humans. Therefore, the powerful Drosophila model system can be used to study concepts of muscle-tendon development that can also be applied to human muscle biology. Here, we describe in detail how morphogenesis of the adult muscle-tendon system can be easily imaged in living, developing Drosophila pupae. Hence, the method allows investigating proteins, cells and tissues in their physiological environment...
February 6, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29443087/a-quantitative-sensory-testing-paradigm-to-obtain-measures-of-pain-processing-in-patients-undergoing-breast-cancer-surgery
#10
Noud van Helmond, Hans Timmerman, Søren S Olesen, Asbjørn M Drewes, Joris Kleinhans, Oliver H Wilder-Smith, Kris C Vissers, Monique A Steegers
Chronic pain following surgery, persistent postsurgical pain, is an important highly prevalent condition contributing to significant symptom burden and lower quality of life. Persistent postsurgical pain is relatively refractory to treatment hence generating a high need for preventive strategies and treatments. Therefore, the identification of patients at risk of developing persistent pain is an area of active ongoing research. Recently it was demonstrated that peri-operative disruptions in central pain processing may be able to predict persistent postsurgical pain at long term follow-up in breast cancer patients...
January 18, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29443022/detecting-behavioral-deficits-in-rats-after-traumatic-brain-injury
#11
Nicole Hausser, Kathia Johnson, Margaret A Parsley, Jutatip Guptarak, Heidi Spratt, Stacy L Sell
With the increasing incidence of traumatic brain injury (TBI) in both civilian and military populations, TBI is now considered a chronic disease; however, few studies have investigated the long-term effects of injury in rodent models of TBI. Shown here are behavioral measures that are well-established in TBI research for times early after injury, such as two weeks, until two months. Some of these methods have previously been used at later times after injury, up to one year, but by very few laboratories. The methods demonstrated here are a short neurological assessment to test reflexes, a Beam-Balance to test balance, a Beam-Walk to test balance and motor coordination, and a working memory version of the Morris water maze that can be sensitive to deficits in reference memory...
January 30, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29443001/short-and-medium-range-structures-of-80gese-sub-2-sub-20ga-sub-2-sub-se-sub-3-sub-chalcogenide-glasses
#12
Elena Petracovschi, Laurent Calvez, Laurent Cormier, David LE Coq, Jincheng Du
The short and medium range structures of the 80GeSe2-20Ga2Se3 (or Ge23.5Ga11.8Se64.7) chalcogenide glasses have been studied by combining ab initio molecular dynamics (AIMD) simulations and experimental neutron diffraction studies. Structure factor and total correlation function were calculated from glass structures generated from AIMD simulations and compared with neutron diffraction experiments showing reasonable agreement. The atom structures of the ternary chalcogenide glasses were analyzed in detailed and it was found that gallium atoms are four-fold coordinated by selenium and form [GaSe4] tetrahedra...
February 14, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/29442592/is-source-information-automatically-available-in-working-memory
#13
Hui Chen, Richard A Carlson, Brad Wyble
We often remember information without its source (e.g., word or picture format). This phenomenon has been studied extensively in long-term memory but rarely in the context of short-term working memory (WM), which leaves open the question of whether source amnesia can result from a lack of memory encoding rather than forgetting. This study provided a series of striking and novel demonstrations showing participants' inability to report the source of a color representation immediately after that color was used in a task and stored in memory...
February 1, 2018: Psychological Science
https://www.readbyqxmd.com/read/29442579/changes-in-cryphonectria-parasitica-populations-affects-natural-biological-control-of-chestnut-blight
#14
Marin Ježić, Jelena Mlinarec, Rosemary Vuković, Zorana Katanić, Ljiljana Krstin, Lucija Nuskern, Igor Poljak, Marilena Idžojtić, Mirta Tkalec, Mirna Curkovic-Perica
Invasive species, especially plant pathogens have a potential to completely eradicate native plant species and remodel landscapes. Tripartite interaction among sweet chestnut, Castanea sativa, chestnut blight-causing invasive fungus, Cryphonectria parasitica, and a hyperparasitic virus, Cryphonectria parasitica hypovirus 1 (CHV1) were studied in two populations. The number of different vegetative compatibility (vc) types of C. parasitica more than doubled over the ten years, while the hypovirulence incidence dropped in one population, and slightly increased in the other one...
February 14, 2018: Phytopathology
https://www.readbyqxmd.com/read/29442543/dolutegravir-dual-therapy-as-maintenance-treatment-in-hiv-infected-patients-a-review
#15
Rosaleen Boswell, Michelle M Foisy, Christine A Hughes
OBJECTIVE: To review available evidence for dolutegravir-based dual therapy as maintenance treatment in HIV-1 infected patients. DATA SOURCES: A literature search was conducted using PubMed, MEDLINE, and Google Scholar to the end of January 2018. Conference abstracts and article bibliographies were also reviewed. STUDY SELECTION AND DATA EXTRACTION: All English-language, randomized, and observational studies were included. DATA SYNTHESIS: In all, 12 studies were identified: 10 were observational, and 2 were randomized trials...
February 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29442241/does-the-number-of-operating-specialists-influence-the-conversion-rate-and-outcomes-after-laparoscopic-colorectal-cancer-surgery
#16
Nader K Francis, Nathan J Curtis, Louise Crilly, Emma Noble, Tamsin Dyke, Rob Hipkiss, Richard Dalton, Andrew Allison, Emad Salib, Jonathan Ockrim
BACKGROUND: Laparoscopic techniques in colorectal surgery have been widely utilised due to short-term patient benefits but conversion to open surgery is associated with adverse short- and long-term patient outcomes. The aim of this study was to investigate the influence of dual specialist operating on the conversion rate and patient outcomes following laparoscopic colorectal surgery. METHODS: A prospectively populated colorectal cancer surgery database was reviewed...
February 13, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29442181/do-functional-outcomes-and-cuff-integrity-correlate-after-single-versus-double-row-rotator-cuff-repair-a-systematic-review-and-meta-analysis-study
#17
Mohamed H Sobhy, Ahmed Hany Khater, Medhat Ragab Hassan, Ossama El Shazly
PURPOSE: The purpose of this study is to perform a systematic review and meta-analysis of all available level I prospective randomized controlled trials comparing arthroscopic single-row (SR) with double-row (DR) rotator cuff repairs by both clinical outcomes and radiological re-tear rates. METHODS: PubMed, EMBASE, Google Scholar, and Cochrane databases search was done for level I RCTs comparing clinical and radiological outcomes after SR versus DR rotator cuff repair...
February 13, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29442177/effectiveness-of-rotigotine-plus-intensive-and-goal-based-rehabilitation-versus-rotigotine-alone-in-de-novo-parkinsonian-subjects-a-randomized-controlled-trial-with-18-month-follow-up
#18
D Ferrazzoli, P Ortelli, G Riboldazzi, R Maestri, G Frazzitta
BACKGROUND: Dopamine Replacement Therapy (DRT) represents the most effective treatment for Parkinson's disease (PD). Nevertheless, several symptoms are unresponsive to treatment and its long-term use leads to serious side effects. To optimize the pharmacological management of PD, dopamine-agonists are often prescribed to "de-novo" patients. Moreover, several studies have shown the effectiveness and the synergic effect of rehabilitation in treating PD. OBJECTIVE: To evaluate the synergism between DRT and rehabilitation in treating PD, by investigating the short and the long-term effectiveness of a multidisciplinary, intensive and goal-based rehabilitation treatment (MIRT) in a group of patients treated with Rotigotine...
February 13, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29441995/short-term-curative-effect-of-s-1-plus-oxaliplatin-as-perioperative-chemotherapy-for-locally-advanced-gastric-cancer-a-prospective-comparison-study
#19
Qun Zhao, Yong Li, Jian Huang, Liqiao Fan, Bibo Tan, Yuan Tian, Peigang Yang, Zhikai Jiao, Xuefeng Zhao, Zhidong Zhang, Dong Wang, Yu Liu
This research aimed to investigate the efficacy of S-1 plus oxaliplatin (SOX) as perioperative chemotherapy for locally advanced gastric cancer. We enrolled 102 patients with preoperative clinical stage T3-4N×M0 gastric cancer who were then randomly assigned to receive SOX as either perioperative chemotherapy (group A, 50 patients) or postoperative adjuvant chemotherapy (group B, 52 patients). Short-term curative efficacy and adverse effects of perioperative chemotherapy were analyzed. The rates of R0 resection, surgical complications, combined multiple organ resection, overall survival (OS), and disease-free survival (DFS) were compared between the groups...
April 1, 2017: Die Pharmazie
https://www.readbyqxmd.com/read/29441804/using-social-media-to-explore-the-consequences-of-domestic-violence-on-mental-health
#20
Mingming Liu, Jia Xue, Nan Zhao, Xuefei Wang, Dongdong Jiao, Tingshao Zhu
A great deal of research has focused on the negative consequences of domestic violence (DV) on mental health. However, current studies cannot provide direct and reliable evidence on the impacts of DV on mental health in a short term as it is not feasible to measure mental health shortly before and after an unpredictable event like DV. This study aims to explore the short-term outcomes of DV on individuals' mental health. We collected a sample of 232 victims (77% female) and 232 nonvictims (gender and location matched with 232 victims) on Sina Weibo...
February 1, 2018: Journal of Interpersonal Violence
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