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https://www.readbyqxmd.com/read/29223522/custom-made-titanium-3d-printed-interbody-cages-for-treatment-of-osteoporotic-fracture-related-spinal-deformity
#1
Timothy Siu, Jeffrey M Rogers, Kainu Lin, Robert Thompson, Mark Owbridge
BACKGROUND: Advances in minimally invasive interbody fusion have greatly enhanced surgeons' capability to correct adult spinal deformity with reduced morbidity. However, the feasibility of such approaches is limited in patients with previous osteoporotic fractures as the resultant vertebral deformity renders the endplate geometry incongruous with conventional interbody implants. Current 3D printing technology offers a novel solution by fabricating custom-made implants tailored to individual anatomy...
December 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29221814/use-of-interventional-radiology-as-initial-hemorrhage-control-to-improve-outcomes-for-potentially-lethal-multiple-blunt-injuries
#2
Hiroyuki Otsuka, Toshiki Sato, Keiji Sakurai, Hiromichi Aoki, Takeshi Yamagiwa, Shinichi Iizuka, Sadaki Inokuchi
INTRODUCTION: Recently, trauma management has been markedly improved with interventional radiology (IVR) and damage-control strategies. However, the indications for its use in hemodynamically unstable patients with severe trauma remains unclear. In some cases, IVR may be more effective than surgery for damage-control hemostasis; however, performing IVR in life-threatening trauma settings is challenging. To address this, we practiced and evaluated a trauma-management system with emergency physicians who trained for both severe trauma management, and techniques of surgery and IVR...
December 6, 2017: Injury
https://www.readbyqxmd.com/read/29218392/unusual-circumstances-to-diagnose-cervical-pott-s-disease
#3
Mohamed Ali Kedous, Ahmed Msakni, Wael Chebbi, Mourad Zaraa, Mohsen Trabelsi
Tuberculous spondylodiscitis usually affects the dorso-lumbar spine, and its cervical location is a rare condition that can mimic other diseases and consequently cause treatment delays. We report a case of tuberculous spondylodiscitis of the lower cervical spine discovered under unusual circumstances in a patient with severe polytrauma involving a cranio-cerebral trauma, a non-displaced fracture of the two laminæ and the spinous process of the C6 vertebrae as well as fibular and tibial shaft fractures. The patient underwent static tibial nailing, and a collar with occipital and chin supports was applied...
December 7, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29216909/which-measuring-site-in-ankylosing-spondylitis-is-best-to-detect-bone-loss-and-what-predicts-the-decline-results-from-a-5-year-prospective-study
#4
Anna Deminger, Eva Klingberg, Mattias Lorentzon, Mats Geijer, Jan Göthlin, Martin Hedberg, Eva Rehnberg, Hans Carlsten, Lennart T Jacobsson, Helena Forsblad-d'Elia
BACKGROUND: Studies have shown increased prevalence of osteoporosis and increased risk for vertebral fractures in patients with ankylosing spondylitis (AS). Measurements of bone mineral density (BMD) in the lumbar spine anterior-posterior (AP) projection may be difficult to interpret due to the ligamentous calcifications, and the lateral projection might be a better measuring site. Our objectives were to investigate BMD changes after 5 years at different measuring sites in patients with AS and to evaluate disease-related variables and medications as predictors for BMD changes...
December 8, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/29214508/bone-histomorphometry-in-acromegaly-patients-with-fragility-vertebral-fractures
#5
L Dalle Carbonare, V Micheletti, E Cosaro, M T Valenti, M Mottes, G Francia, M V Davì
CONTEXT: The high risk of vertebral fractures (VFs) in acromegaly patients despite normal bone mineral density (BMD) is well known. The reasons for this paradoxical finding of skeleton fragility are poorly understood due to the limited data on bone histomorphometry in acromegaly. OBJECTIVE: This study aimed to analyze histomorphometric parameters including bone microarchitecture in acromegaly patients with VFs and normal BMD compared to normal subjects, and also to evaluate the differences between active and controlled acromegaly patients...
December 6, 2017: Pituitary
https://www.readbyqxmd.com/read/29214357/investigation-and-analysis-of-osteoporosis-falls-and-fragility-fractures-in-elderly-people-in-the-beijing-area-a-study-on-the-bone-health-status-of-elderly-people-%C3%A2-%C3%A2-80%C3%A2-years-old-with-life-self-care
#6
Jian Zhou, Ming-Zhao Qin, Qian Liu, Jin-Ping Liu
Among ≥ 80 years old and under life self-care in the Beijing area, the prevalences of osteoporosis, falls, and fragility fracture were high; and these prevalences were even higher in women. The treatment rate of osteoporosis is very low. Therefore, comprehensive and standardized prevention and treatment should be promoted. PURPOSE: The purpose of this study is to investigate prevalence of osteoporosis, falls, and fragility fractures in this population, and analyze related factors, in order to provide a basis for standardized prevention and treatment...
December 6, 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29209416/reliability-of-analysis-of-the-bone-mineral-density-of-the-second-and-fifth-metatarsals-using-dual-energy-x-ray-absorptiometry-dxa
#7
N Stewart Pritchard, James M Smoliga, Anh-Dung Nguyen, Micah C Branscomb, David R Sinacore, Jeffrey B Taylor, Kevin R Ford
Background: Metatarsal fractures, especially of the fifth metatarsal, are common injuries of the foot in a young athletic population, but the risk factors for this injury are not well understood. Dual-energy x-ray absorptiometry (DXA) provides reliable measures of regional bone mineral density to predict fracture risk in the hip and lumbar spine. Recently, sub-regional metatarsal reliability was established in fresh cadaveric specimens and associated with ultimate fracture force. The purpose of this study was to assess the reliability of DXA bone mineral density measurements of sub-regions of the second and fifth metatarsals in a young, active population...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29208525/novel-familial-mutation-of-lrp5-causing-high-bone-mass-genetic-analysis-clinical-presentation-and-characterization-of-bone-matrix-mineralization
#8
K M Roetzer, G Uyanik, A Brehm, J Zwerina, S Zandieh, T Czech, P Roschger, B M Misof, K Klaushofer
The Wnt signalling pathway is a critical regulator of bone mass and quality. Several heterozygous mutations in the LRP5 gene, a Wnt co-receptor, causing high bone mass (LRP5-HBM) have been described to date. The pathogenic mechanism is thought to be a gain-of-function caused by impaired inhibition of the canonical Wnt signalling pathway, thereby leading to increased bone formation. We report the cases of two affected family members, a 53-year-old mother and her 23-year-old daughter, with high bone mass (T-scores mother: lumbar spine 11...
December 5, 2017: Bone
https://www.readbyqxmd.com/read/29207490/is-trabecular-bone-score-valuable-in-bone-microstructure-assessment-after-gastric-bypass-in-women-with-morbid-obesity
#9
Agustina Pia Marengo, Fernando Guerrero Pérez, Luis San Martín, Rosa Monseny, Anna Casajoana, Rocio Valera, Nuria Virgili, Andreu Simó Servat, Albert Prats, Carmen Gómez-Vaquero, Nuria Vilarrasa
INTRODUCTION: The effects of bariatric surgery on skeletal health raise many concerns. Trabecular bone score (TBS) is obtained through the analysis of lumbar spine dual X-ray absorptiometry (DXA) images and allows an indirect assessment of skeletal microarchitecture (MA). The aim of our study was to evaluate the changes in bone mineral density (BMD) and alterations in bone microarchitecture assessed by TBS in morbidly obese women undergoing Roux-en-Y gastric bypass (RYGB), over a three-year follow-up...
December 2, 2017: Nutrients
https://www.readbyqxmd.com/read/29206823/-thoracic-and-lumbar-fractures-in-adolescents-an-eight-year-study
#10
Félix Adolfo Sánchez-Chávez, Jorge Arturo Cabrera-Escamilla
METHODS: In order to know the characteristics of these lesions in our environment and compare with those the adults, a transversal and descriptive study of adolescents between 12 and 18 years who were hospitalized for thoracic and lumbar fracture in two centers of high level trauma in our country for 8 years was performed. The variables studied were applied statistical analysis descriptive and correlation. RESULTS: They were found significant date by associating the causes of damage with associated lesions (p = 0...
November 2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/29204490/lumbar-chance-fracture-after-direct-anterior-total-hip-arthroplasty
#11
Michael Pitta, Corey J Wallach, Colleen Bauk, William G Hamilton
This report describes a patient with ankylosing spondylitis (AS) who underwent total hip arthroplasty (THA) by the direct anterior approach and sustained a L4-5 extension fracture dislocation with neural deficits. A magnetic resonance imaging revealed an epidural hematoma at the site of the fracture causing critical stenosis. The patient was taken to the operating room for a L3-S1 posterior decompression with L2-pelvis posterior spinal fusion. AS and diffuse idiopathic skeletal hyperostosis create a stiff spine that predisposes to fractures because of the larger moment arms experienced than normal spines...
December 2017: Arthroplasty Today
https://www.readbyqxmd.com/read/29204193/management-and-outcome-analysis-of-pediatric-unstable-thoracolumbar-spine-injury-large-surgical-series-with-literature-review
#12
REVIEW
Guru Dutta Satyarthee, M Sangani, Sumit Sinha, Deepak Agrawal
Pediatric thoracolumbar spine fractures are considered rare injuries with paucity of publication across the globe. Further, spine injuries in children are comparatively rarer, and pediatric spine differs from adults, both biomechanically and anatomically; so, adult spine management strategy cannot be applied to pediatric cases, and exact guidelines for management of pediatric spinal injury is lacking. The current study is undertaken to study epidemiology, surgical management, and outcome of pediatric dorsolumbar unstable spine injury...
July 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29201845/k%C3%A3-mmell-s-disease-treated-with-percutaneous-vertebroplasty-minimum-1-year-follow-up
#13
Jae Won Park, Jong-Hwa Park, Hong Jun Jeon, Jong Young Lee, Byung Moon Cho, Se-Hyuck Park
Objective: To evaluate the radiographic and clinical outcomes of percutaneous vertebroplasty (PVP) in patients with Kümmell's disease. Methods: A retrospective review was conducted for 19 vertebrae in 18 patients, between January 2012 and June 2016. A visual analogue scale (VAS) score was used to determine each patient's subjective level of pain (0=no pain to 10=severe pain) preoperative, immediately postoperative and at the last follow-up (at least 12 months after PVP)...
October 2017: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/29201578/vertebral-compression-fractures-after-lumbar-instrumentation
#14
Michelle Granville, Aldo Berti, Robert E Jacobson
Lumbar spinal stenosis (LSS) is primarily found in an older population. This is a similar demographic group that develops both osteoporosis and vertebral compression fractures (VCF). This report reviewed a series of patients treated for VCF that had previous lumbar surgery for symptomatic spinal stenosis. Patients that only underwent laminectomy or fusion without instrumentation had a similar distribution of VCF as the non-surgical population in the mid-thoracic, or lower thoracic and upper lumbar spine. However, in the patients that had previous short-segment spinal instrumentation, fractures were found to be located more commonly in the mid-lumbar spine or sacrum adjacent to or within one or two spinal segments of the spinal instrumentation...
September 29, 2017: Curēus
https://www.readbyqxmd.com/read/29201304/minimally-invasive-plate-osteosynthesis-using-a-screw-compression-method-for-treatment-of-humeral-shaft-fractures
#15
Sang-Hun Ko, Jae-Ryong Cha, Chae Chil Lee, Yong Tae Joo, Kyeong Su Eom
Background: This study aims to compare the surgical outcomes of open reduction and internal fixation (ORIF) and minimally invasive plate osteosynthesis (MIPO) using a screw compression method in simple humeral shaft fractures. Methods: This retrospective study was performed with 50 patients who had surgical interventions for the treatment of simple humeral shaft fractures and had follow-ups of at least 12 months in Ulsan University Hospital between August 2008 and June 2015...
December 2017: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/29200862/association-between-serum-cystatin-c-and-bone-mineral-density-in-korean-adults
#16
Dongwon Yi, Ah Reum Khang, Hye Won Lee, Seok Man Son, Yang Ho Kang
Background: Serum cystatin C has been known as a novel marker of preclinical renal dysfunction, and higher cystatin C levels are associated with increased risks of hip and nonvertebral fractures. However, there are few reports on the association between serum cystatin C and bone mineral density (BMD), especially in the Asian population. We evaluated the association between cystatin C levels and BMD of the spine and hip in Korean adults. Methods: A cross-sectional study was performed in 865 Korean adults (325 men and 540 women) who participated in a comprehensive medical examination program and underwent bone densitometry...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29196764/differences-in-trabecular-microarchitecture-and-simplified-boundary-conditions-limit-the-accuracy-of-qct-based-finite-element-models-of-vertebral-failure
#17
Amira I Hussein, Daniel Louzeiro, Ginu U Unnikrishnan, Elise F Morgan
Vertebral fractures are common in the elderly, but efforts to reduce their incidence have been hampered by incomplete understanding of the failure processes that are involved. This study's goal was to elucidate failure processes in the lumbar vertebra and to assess the accuracy of quantitative computed tomography (QCT)-based finite element (FE) simulations of these processes. Following QCT scanning, spine segments (n=27) consisting of L1 with adjacent intervertebral discs and neighboring endplates of T12 and L2 were compressed axially in a stepwise manner...
December 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/29191468/malunion-of-post-traumatic-thoracolumbar-fractures
#18
REVIEW
C Mazel, L Ajavon
Thoracolumbar malunion is the result of loss of correction, insufficient correction, or even no correction (both in the frontal and sagittal planes) of a thoracolumbar fracture. The main causes are incorrect assessment of the fracture's complexity (burst fracture), its potential progression to kyphosis, and associated disc or ligament damage. It can also be the result of a poorly conducted initial treatment. The types of malunion have changed over the years because of the introduction of vertebroplasty and kyphoplasty...
November 27, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29191100/preliminary-results-of-anterior-lumbar-interbody-fusion-anterior-column-realignment-for-the-treatment-of-sagittal-malalignment
#19
Pooria Hosseini, Gregory M Mundis, Robert K Eastlack, Ramin Bagheri, Enrique Vargas, Stacie Tran, Behrooz A Akbarnia
OBJECTIVE Sagittal malalignment decreases patients' quality of life and may require surgical correction to achieve realignment goals. High-risk posterior-based osteotomy techniques are the current standard treatment for addressing sagittal malalignment. More recently, anterior lumbar interbody fusion, anterior column realignment (ALIF ACR) has been introduced as an alternative for correction of sagittal deformity. The objective of this paper was to report clinical and radiographic results for patients treated using the ALIF-ACR technique...
December 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/29189523/bilateral-sacral-ala-fractures-are-strongly-associated-with-lumbopelvic-instability
#20
Julius A Bishop, Sean Dangelmajer, Ian Corcoran-Schwartz, Michael J Gardner, Milton L Chip Routt, Tiffany N Castillo
OBJECTIVES: To quantify the incidence of lumbopelvic instability in the setting of unilateral and bilateral sacral fractures and assess whether the presence of bilateral sacral fractures on axial imaging is a useful screening test for lumbopelvic instability. DESIGN: Retrospective case series. SETTING: Level I trauma center at an academic medical center. PATIENTS/PARTICIPANTS: A hospital database was used to identify patients diagnosed with a sacral fracture by The International Classification of Diseases, Ninth Revision (ICD-9) code from 2000 to 2014...
December 2017: Journal of Orthopaedic Trauma
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