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Glaucia Vanessa Novak, Koken Hayashi, Kohei Sampa, Yosuke Okumura, Gabriela Ribeiro Viola Ferreira, Clovis Artur Silva
Arthritis has been reported as an acute pattern, generally evanescent with oligoarthritis, mostly affecting knees and ankles in childhood systemic polyarteritis nodosa. However, chronic polyarthritis with morning stiffness mimicking juvenile idiopathic arthritis has not been reported. We describe the case of a 4-year old girl who had additive and chronic polyarthritis with edema, tenderness, pain on motion and morning stiffness for 2 months. After 45 days, she also presented painful subcutaneous nodules and erythematous-violaceous lesions in the extensor region of upper and lower limbs...
January 2017: Einstein
Daniela Marasovic-Krstulovic, Zrinka Jurisic, Dijana Perkovic, Jure Aljinovic, Dusanka Martinovic-Kaliterna
We present a case of fulminant diffuse systemic sclerosis (dSSc) developed after the aortic valve replacement followed by fatal congestive heart failure within the 6 months from the initial symptoms. A 61-year-old male developed rapidly progressive diffuse systemic sclerosis following aortic valve replacement due to stenosis of bicuspid aortic valve. He presented with diarrhoea, weight loss, mialgia and arthralgia after cardiac surgery. Heart failure, due to myocardial fibrosis, was noted as a cause of death...
June 2014: Medical Hypotheses
Mohsen Zeeb, Parisa Tayebi Jamil, Ali Berenjian, Mohammad Reza Ganjali, Mohamad Reza Talei Bavil Olyai
BACKGROUND: Piroxicam (PXM) belongs to the wide class of non-steroidal anti-inflammatory drugs (NSAIDs). PXM has been widely applied in the treatment of rheumatoid arthritis, gonarthrosis, osteoarthritis, backaches, neuralgia, mialgia. In the presented work, a green and benign sample pretreatment method called temperature-controlled ionic liquid dispersive liquid phase microextraction (TCIL-DLPME) was followed with stopped-flow injection spectrofluorimetry (SFIS) for quantitation of PXM in pharmaceutical formulations and biological samples...
2013: Daru: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences
Paulo R Machado, Julia Ampuero, Luiz H Guimarães, Leonardo Villasboas, Ana T Rocha, Albert Schriefer, Rosana S Sousa, Anette Talhari, Gerson Penna, Edgar M Carvalho
BACKGROUND: Cutaneous leishmaniasis (CL) is treated with parenteral drugs for decades with decreasing rate cures. Miltefosine is an oral medication with anti-leishmania activity and may increase the cure rates and improve compliance. METHODOLOGY/PRINCIPAL FINDINGS: This study is a randomized, open-label, controlled clinical trial aimed to evaluate the efficacy and safety of miltefosine versus pentavalent antimony (Sb(v)) in the treatment of patients with CL caused by Leishmania braziliensis in Bahia, Brazil...
December 21, 2010: PLoS Neglected Tropical Diseases
Luciana de Almeida Silva Teixeira, Juliana Salviano Mendonça Lopes, André Guilherme da Costa Martins, Fernando Augusto Batista Campos, Sybelle de Souza Castro Miranzi, Gabriel Antônio Nogueira Nascentes
The clinical picture of dengue is characterized by a maximum duration of 14 days despite frequent complaints of longer symptoms. This study evaluated the occurrence of persistent symptoms (> 14 days) and its impact on daily life. A hundred eighteen patients were interviewed, and the main symptoms at diagnosis were mialgia (98.3%), fever (97.5%) and weakness (95.8%). The presence of at least a persistent symptom was related by 77 (65.2%) individuals of wich 10 (8.5%) described it as intense and lasting for 30 days or more...
March 2010: Cadernos de Saúde Pública
Z D Sikharulidze, M G Kopaliani, L O Kilasoniia
The purpose of this study was the evaluation of clinical heroin symptoms and buprenorphine drug addiction in the withdrawal period with the purpose of their comparison, study of parameters of bone metabolism in the both groups. In the study group were included 40 patients with heroin and 27 with buprenorphine addiction in the period of abstinence. Our investigations have shown, that in the both groups, among clinical symptoms ossalgias, arthralgias and mialgias attributes to the expressed dysfunction of vegetative system, were most prominent...
May 2006: Georgian Medical News
Natalino Hajime Yoshinari, Milena Garcia Abrão, Virginia Lúcia Nazário Bonoldi, Cleber Oliveira Soares, Claudio Roberto Madruga, Alessandra Scofield, Carlos Luis Massard, Adivaldo Henrique da Fonseca
This paper reports a case of coinfection caused by pathogens of Lyme disease and babesiosis in brothers. This was the first case of borreliosis in Brazil, acquired in Cotia County, State of S o Paulo, Brazil. Both children had tick bite history, presented erythema migrans, fever, arthralgia, mialgia, and developed positive serology (ELISA and Western-blotting) directed to Borrelia burgdorferi G 39/40 and Babesia bovis antigens, mainly of IgM class antibodies, suggestive of acute disease. Also, high frequencies of antibodies to B...
April 2003: Memórias do Instituto Oswaldo Cruz
Mihaela Cătălina Luca, Carmen Dorobăţ, Carmen Corcaci, Roxana Scurtu, V Luca, Doina Mihalache
Leptospirosis is a zooantroponosis manifested as an infectious disease with a severe evolution, with liver and renal failure and hemorrhagic manifestation. The aim of this study was to present the clinico-biological investigation and the therapeutical aspects of 256 cases of leptospirosis admitted in the Infectious Diseases Hospital Iasi during 4 years (1998-2001). The diagnosis was based on the study of clinico-biological and therapeutical parameters (risk factors, fever, mialgia, headache, algic, eruptive, meningeal, hepatorenal, hemorrhagic syndromes with the serological evidence of the serotypes of leptospirosis); most of the cases were registered in 1998 (23% cases), in adults (31...
April 2002: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
Ubaldo O Martín, Alcides Sensevy, Javier Colombo, Victor Tramontin
Leptospirosis is produced by a bacteria belonging to the Leptospira genus. Water contaminated with this germ which comes from the urine of infected animals is an excellent source of infection for mammals. It gets into the human body through the skin or mucus. The aims of this work were to describe the cases that occurred during the first five months of 2001, and to determine the causes of this phenomenon. There was a total of 49 patients confirmed by the laboratory, 39 of whom completed the epidemiologic form; 24 of whom were over 15 years of age, 19 were male cases, 13 of whom involved in semiurban jobs; 82% presented fever, 74...
2002: Medicina
J Gascón, V Giner, J Vidal, J M Jou, E Mas, M Corachán
Dengue infection is nowadays considered a re-emergent disease. It has a worldwide tropical and subtropical distribution. The dengue virus in a member of the flavivirus family composed by 4 different serotypes. The virus is transmitted by mosquitos of the Aedes genus. With the increment of travels to the endemic areas, dengue is now observed frequently in our country. We analyzed 57 patients, 30 with imported dengue (ID) and 27 with dengue fever suffered during the trip (DDT). This series is compared with other published ones and a review of the subject is presented...
November 7, 1998: Medicina Clínica
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