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ovary teratoma

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https://www.readbyqxmd.com/read/28050596/an-ovarian-mature-cystic-teratoma-evolving-in-squamous-cell-carcinoma-a-case-report-and-review-of-the-literature
#1
REVIEW
C Goudeli, A Varytimiadi, N Koufopoulos, J Syrios, E Terzakis
Mature cystic teratomas (MCT), also known as dermoid cysts, are the most common ovarian germ cell tumors and the most common ovarian neoplasms in patients younger than 20 years. Malignant transformation (MT) is a rare complication of MCTs which may occur in 1-2% of the cases. Squamous cell carcinoma (SCC) is the most frequent histology arising from MCTs and its appearance depends on diverse risk factors such as patient's age, the size of the tumor and levels of serum tumor markers. Diagnosis and treatment constitute a big challenge due to the rarity and the aggressive course of this entity...
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28042664/well-formed-cerebellum-and-brainstem-like-structures-in-a-mature-ovarian-teratoma-neuropathological-observations
#2
Masayuki Shintaku 新宅雅幸, Toshiko Sakuma, Chiho Ohbayashi, Motoyoshi Maruo
In the surgical case of a mature cystic teratoma of the ovary that arose in a 16-year-old girl, a large amount of well-differentiated and highly organized cerebellar tissue was found. Three layers of the cerebellar cortex were well formed, and synaptophysin-positive "glomeruli" were found in the granule cell layer. Some Purkinje cells exhibited focal expansion and a dysmorphic appearance of the dendrites. Adjacent to the cerebellar tissue, a large space lined by the ependymal layer and a club-shaped CNS tissue mass resembling the brainstem were found, and structures reminiscent of the midbrain tectum and pontine nuclei were distinguished within this mass...
January 2, 2017: Neuropathology: Official Journal of the Japanese Society of Neuropathology
https://www.readbyqxmd.com/read/28040316/ovarian-teratoma-development-after-anti-nmda-receptor-encephalitis-treatment
#3
Taku Omata, Kazuo Kodama, Yoshimi Watanabe, Yukiko Iida, Yoshiaki Furusawa, Akiko Takashima, Yukitoshi Takahashi, Hiroshi Sakuma, Keiko Tanaka, Katsunori Fujii, Naoki Shimojo
BACKGROUND: Anti-NMDA-R receptor encephalitis occurs predominantly in younger women and is often comorbid with ovarian teratoma, a feature that is often absent in children. Here, we report our experience with two pediatric patients, in whom no tumors were present during treatment for encephalitis, but in whom ovarian teratomas developed without encephalitis relapse after treatment was completed. CASES: Patient 1 was a 14-year-old girl who was diagnosed due to characteristic symptoms and anti-NMDA-R antibody...
December 28, 2016: Brain & Development
https://www.readbyqxmd.com/read/28018955/wilms-tumor-of-the-ovary
#4
Vinita M Alexander, Jane Meisel, Shannon O'Brien, Namita Khanna
Extrarenal Wilms' tumor of the ovary is a very rare tumor likely derived from embryonic mesonephros. We present the first reported case of a teratoid extrarenal Wilms' tumor of the ovary with a short review of the existing literature. In the case, a 26-year-old woman presented with back pain and was found to have a dermoid cyst; three years later, she presented again, now pregnant, with severe abdominal pain. She was diagnosed with an immature teratoma consisting of a Wilms' tumor (immature component) arising within a mature teratoma and treated exclusively with surgery and surveillance...
February 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28018806/management-of-familial-ovarian-teratoma-the-need-for-guidance
#5
Sarah Braungart, Majella McCullagh
Ovarian teratomas in prepubertal females are uncommon, but familial ones are exceedingly rare. We report an ovarian teratoma in an 8-year-old girl, her mother, and her maternal grandmother. The risk of a metachronous tumor and subsequent complications (such as torsion) in the contralateral ovary remain unclear. There is no clear guidance on follow-up management of patient and family members in the literature. We have reviewed the literature and discuss the challenges for the pediatric surgeon arising from such cases...
December 2016: European Journal of Pediatric Surgery Reports
https://www.readbyqxmd.com/read/28017339/malignant-oestrogen-producing-teratoma-in-a-cat
#6
Y Machida, M Michishita, M Wada, T Hori, E Kawakami, H Yoshimura, K Ohkusu-Tsukada, K Taya, K Takahashi
A 5-year-old female domestic shorthair cat was presented with abdominal distension and serum biochemical evaluation indicated a high concentration of oestradiol (32.81 pg/ml). Exploratory laparotomy revealed a large cystic mass in the right ovary with cystic fluid containing a high level of oestradiol (18.80 pg/ml). The tumour was composed of immature neuroectodermal tissue, mature cartilage, smooth muscle, adipose tissue and aggregated, poorly differentiated mesenchymal cells. It contained cysts of various sizes that were lined by epithelium of different types...
December 22, 2016: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/28009311/-malignant-tumors-in-ovarian-mature-cystic-teratomas-intraoperative-diagnostic-basis
#7
A Khachatryan
Extremely rare ovarian primary tumors formed in a mature cystic teratomaare described in the literature. This research work studies the frequency of malignant mature cystic teratoma, as well as their clinical and morphological features and necessity of intraoperative histological examination of all teratomas. Cases histories of 56 patients, suffering from ovarian mature cystic teratomahave been studied in MC Shengavit in the period of 2003 - 2015. Among them 4 patients with the somatic malignancies were identified...
November 2016: Georgian Medical News
https://www.readbyqxmd.com/read/27987343/mature-cystic-teratoma-coexisting-with-clear-cell-carcinoma-in-the-ovary
#8
Koki Shimura, Mariko Matsumoto, Takuya Sugahara, Takuro Yamamoto, Nozomi Ogiso, Yoji Urata, Tomoharu Okubo
Mature cystic teratoma (MCT) is the most common benign ovarian tumor; clear-cell carcinoma (CCC) is a relatively common malignant ovarian tumor in Japan, but there are few reports on the coexistence of MCT and CCC. Here we report a case of simultaneous MCT and CCC in the ovary and review the relevant literature. The patient was a 49-year-old woman. A 5-cm MCT was found in the left ovary on initial gynecological examination, and she was referred to hospital for treatment because it was expanding. Magnetic resonance imaging showed a multilocular cystic tumor 16 × 10 × 9...
December 17, 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27981940/squamous-cell-carcinoma-arising-in-background-of-mature-cystic-teratoma
#9
Muhammad Zubair, Shoaib Naiyar Hashmi, Saeed Afzal, Iqbal Muhammad, Hafeez Ud Din, Syed Naeem Raza Hamdani
Mature cystic teratoma of ovary is a common benign adnexal tumor in females. Malignant transformation in a mature cystic teratoma of the ovary occurs in only 1 - 2% of cases. Most common malignant transformation is squamous cell carcinoma (70-80% of cases), occurring mostly in postmenopausal women with large sized cysts. Here, we report a case of 46-year lady who presented with pain in lower abdomen. Ultrasound and CT scan revealed complex adnexal mass measuring 16x9 cm. Size and older age of the patients should be regarded as important predictors of malignant transformation in mature cystic teratoma...
November 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27938333/pseudomyxoma-peritonei-of-a-mature-ovarian-teratoma-caused-by-mismatch-repair-deficiency-in-a-patient-with-lynch-syndrome-a-case-report
#10
Yoshimasa Gohda, Rei Noguchi, Tomoko Horie, Toru Igari, Harumi Nakamura, Yasunori Ohta, Kiyoshi Yamaguchi, Tsuneo Ikenoue, Seira Hatakeyama, Nozomi Yusa, Yoichi Furukawa, Hideaki Yano
BACKGROUND: Pseudomyxoma peritonei (PMP) is a rare disease with an estimated incidence of 1-2 cases per million individuals per year. PMP is characterized by the accumulation of abundant mucinous or gelatinous fluid derived from disseminated tumorous cells. Most of the tumorous cells are originated from rupture of appendiceal neoplasms, but some are from the metastasis of cancer of the colon, ovary, fallopian tube, urachus, colorectum, gallbladder, stomach, pancreas, lung and breast. Although frequent mutations in KRAS and/or GNAS genes have been reported, precise molecular mechanism underlying PMP remains to be elucidated...
December 9, 2016: BMC Medical Genetics
https://www.readbyqxmd.com/read/27843812/an-unusual-case-of-malignant-struma-ovarii-causing-thyrotoxicosis
#11
Elli Anagnostou, Antonios Polymeris, Georgios Morphopoulos, Alexios Travlos, Vassiliki Sarantopoulou, Irini Papaspyrou
BACKGROUND: Struma ovarii (SO) is a specialized monodermal teratoma predominantly composed of mature thyroid tissue, accounting for approximately 5% of all ovarian teratomas. Thyrotoxicosis is seen in about 8% of patients with SO. Most SO cases are benign with only 5-10% being malignant, and malignant SO causing thyrotoxicosis is very uncommon. CASE: A 64-year-old woman had been diagnosed with thyrotoxicosis 2 years previously. The thyroid gland was palpable with a micronodular texture, and the patient was euthyroid under carbimazole...
September 2016: European Thyroid Journal
https://www.readbyqxmd.com/read/27801756/ovarian-epithelial-inclusions-with-mucinous-differentiation-a-clinicopathologic-study-of-42-cases
#12
Jeffrey D Seidman, Jayashree Krishnan
Ovarian epithelial inclusions lined by mucinous epithelium are rare and of uncertain origin. Ovaries containing such inclusions were studied in 42 women. The inclusions were divided into 3 groups: serous epithelial lined with typical ciliated morphology but with distinct basophilic cytoplasmic mucin in some or all of the lining cells, those lined by typical mucinous epithelium, and those lined by a combination of typical mucinous epithelium and serous epithelium. The mean patient age was 61.5 years. Pure mucinous inclusions were found in 27 patients, serous-type inclusions with cytoplasmic mucin in 20, and mixed type in 10...
October 31, 2016: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/27793140/rare-case-of-complete-colon-structure-in-a-mature-cystic-teratoma-of-the-ovary-in-menopausal-woman-a-case-report
#13
Eun Young Ki, Dong Gyu Jang, Dong Jun Jeong, Chang Jin Kim, Sung Jong Lee
BACKGROUND: Mature cystic teratoma (MCT) of the ovary is benign germ cell tumor and shows the highest incidence in women of reproductive age. Histologically, it includes components derived from endoderm, mesoderm, and ectoderm. Although there have been many reports of MCT having small part of the intestinal component, ovarian MCT containing complete colon structure was very rare. CASE PRESENTATION: A 54-year-old woman underwent laparoscopic left salpingo-oophorectomy due to an incidentally found ovarian mass...
October 28, 2016: BMC Women's Health
https://www.readbyqxmd.com/read/27776544/anti-n-methyl-d-aspartate-receptor-encephalitis-with-an-imaging-invisible-ovarian-teratoma-a-case-report
#14
Zainab M Abdul-Rahman, Peter K Panegyres, Margareta Roeck, David Hawkins, Jude Bharath, Paul Grolman, Cliffe Neppe, David Palmer
BACKGROUND: Anti-N-methyl-D-aspartate receptor encephalitis is a recently discovered disease entity of paraneoplastic limbic encephalitis. It largely affects young women and is often associated with an ovarian teratoma. It is a serious yet treatable condition if diagnosed early. Its remedy involves immunotherapy and surgical removal of the teratoma of the ovaries. This case of anti-N-methyl-D-aspartate receptor encephalitis involves an early surgical intervention with bilateral oophorectomy, despite negative imaging evidence of a teratoma...
October 24, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27769689/fetiform-teratoma-in-the-ovary-of-a-7-year-old-girl-a-case-report
#15
Hanna R Goldberg, Lisa Allen, Sari Kives
BACKGROUND: Fetiform teratoma, a highly differentiated mature cystic teratoma resembling a fetus, is rare and typically found in the ovaries of women of reproductive age. In this report we describe, to our knowledge, the youngest case of ovarian fetiform teratoma. CASE: A 7-year-old girl presented with acute abdominal pain. Radiological examinations revealed a 5.2-cm ovarian complex cystic mass with fetal-like components in favor of fetus in fetu and teratoma. After surgical removal, the mass resembled a fetus consisting of a head, two eye slits, two small upper limb projections, and hair...
October 18, 2016: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/27769025/primary-retroperitoneal-mature-cystic-teratoma-in-an-adult-a-case-report
#16
Hassan Peyvandi, Fahimeh Arsan, Athena Alipour-Faz, Maryam Yousefi
BACKGROUND: Mature cystic teratoma is one of the most common tumors of the ovaries; however, primary retroperitoneal lesions are rare entities in adults. CASE SUMMARY: We report a case of a 33 year-old woman noticing a mass in her epigastric and left upper abdominal region without any specific signs and symptoms. Radiological evaluation revealed a retroperitoneal mass with extension from the posterior aspect of the pancreas to the pelvic cavity, composed of calcifications and cystic elements...
October 11, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27702736/a-huge-ovarian-mucinous-cystadenoma-associated-with-contralateral-teratoma-and-polycystic-ovary-syndrome-in-an-obese-adolescent-girl
#17
Patcharapa Thaweekul, Yuthadej Thaweekul, Karicha Mairiang
A 13-year-old, obese girl presented with acute abdominal pain with abdominal distension for a year. The physical examination revealed marked abdominal distension with a large well-circumscribed mass sized 13×20 cm. Her body mass index (BMI) was 37.8 kg/m2. An abdominal CT scan revealed a huge multiloculated cystic mass and a left adnexal mass. She had an abnormal fasting plasma glucose and low HDL-C. Laparotomy, right salpingooophorectomy, left cystectomy, lymph node biopsies and partial omentectomy were performed...
December 2016: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27663301/laparoscopic-outcomes-of-adnexal-surgery-in-older-children-and-adolescents
#18
Ozlem Dural, Cenk Yasa, Ercan Bastu, Funda Gungor Ugurlucan, Gamze Yilmaz, Bahar Yuksel, Suleyman Engin Akhan, Faruk Buyru
STUDY OBJECTIVE: To evaluate the outcomes of laparoscopic surgery for the treatment of adnexal pathology in older children and adolescents. DESIGN: A retrospective cohort review. SETTING: A tertiary academic center in Istanbul, Turkey. PARTICIPANTS: Pediatric and adolescent patients aged between 9 and 19 years (n = 69) who underwent laparoscopic surgery for adnexal pathology from January 2005 through September 2015. The patients who were pregnant or with non-gynecologic pathology detected during surgery were excluded from the study...
February 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/27636886/mature-and-immature-solid-teratomas-involving-uterine-corpus-cervix-and-ovary
#19
Simona Stolnicu, Emoke Szekely, Calin Molnar, Claudiu V Molnar, Iulia Barsan, Valeria D'Alfonso, Cosmin Moldovan, Gang Zheng, Brigitte M Ronnett, Robert A Soslow
Extragonadal teratomas are rare, and localization in the endometrium and cervix is exceptional, with fewer than 10 case reports documented so far in the English literature. We report here the case of a 46-year-old patient who presented with simultaneous immature teratoma in the endometrium and mature teratomas in the ovary in association with gliomatosis peritonei but with no evidence of gestational origin; she subsequently developed multiple solid mature teratomas in the cervix and parauterine tissue. No other similar cases have been previously reported to our knowledge...
September 15, 2016: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/27623329/-ovarian-carcinoid-tumor-responsible-of-permanent-facial-erythrosis-and-flushings-during-sexual-intercourse
#20
B Talvande, A Dorange, M Lecouflet, M Le Nezet, B Kianifard, H Maillard, M Duquenne
INTRODUCTION: Ovarian neuroendocrine tumors are extremely rare. In the ovary, the term of neuroendocrine tumor is usually related to carcinoid tumors although it may be sometimes applied to neuroendocrine carcinomas of non-small cells or small cells cancers usually occurring in the lungs. These carcinoid tumors may develop de novo or from other tumors including teratomas. CASE REPORT: We report a patient who presented with an ovarian carcinoid tumor developed, near or from a dermoid cyst, which was original by its mode of discovery in the dermatology department...
November 2016: La Revue de Médecine Interne
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