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https://www.readbyqxmd.com/read/27911871/inhibition-of-cancer-antioxidant-defense-by-natural-compounds
#1
Alicja Sznarkowska, Anna Kostecka, Katarzyna Meller, Krzysztof Piotr Bielawski
All classic, non-surgical anticancer approaches like chemotherapy, radiotherapy or photodynamic therapy kill cancer cells by inducing severe oxidative stress. Even tough chemo- and radiotherapy are still a gold standard in cancer treatment, the identification of non-toxic compounds that enhance their selectivity, would allow for lowering their doses, reduce side effects and risk of second cancers. Many natural products have the ability to sensitize cancer cells to oxidative stress induced by chemo- and radiotherapy by limiting antioxidant capacity of cancer cells...
November 30, 2016: Oncotarget
https://www.readbyqxmd.com/read/27911141/mindfulness-based-intervention-for-perinatal-grief-in-rural-india-improved-mental-health-at-12%C3%A2-months-follow-up
#2
Lisa R Roberts, Susanne B Montgomery
Stillbirth is a significant global health problem that frequently results in perinatal grief with compound negative psychosocial impact. In low-resource settings with exceedingly high stillbirth rates, such as rural Chhattisgarh, India, it is vital to utilize low-cost, effective interventions. Mindfulness-based stress reduction is an evidence-based intervention utilized for a broad range of physical and mental health problems, and is adaptable to specific populations. The objective of this study was to explore the sustained effectiveness of a shortened, culturally adapted mindfulness-based intervention (MBI) designed to address complex grief after stillbirth...
December 2, 2016: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/27909646/the-neural-mechanisms-of-meditative-practices-novel-approaches-for-healthy-aging
#3
REVIEW
Bianca P Acevedo, Sarah Pospos, Helen Lavretsky
OBJECTIVES: Meditation has been shown to have physical, cognitive, and psychological health benefits that can be used to promote healthy aging. However, the common and specific mechanisms of response remain elusive due to the diverse nature of mind-body practices. METHODS: In this review, we aim to compare the neural circuits implicated in focused-attention meditative practices that focus on present-moment awareness to those involved in active-type meditative practices (e...
2016: Current Behavioral Neuroscience Reports
https://www.readbyqxmd.com/read/27905829/post-traumatic-stress-disorder-dimensions-and-asthma-morbidity-in-world-trade-center-rescue-and-recovery-workers
#4
Irina Mindlis, Esperanza Morales-Raveendran, Emily Goodman, Kevin Xu, Clara Vila-Castelar, Kristine Keller, Ginger Crawford, Shynah James, Craig Katz, Laura E Crowley, Rafael E de la Hoz, Steven Markowitz, Juan P Wisnivesky
Objective Using data from a cohort of World Trade Center (WTC) rescue and recovery workers with asthma, we assessed whether meeting criteria for post-traumatic stress disorder (PTSD), sub- PTSD and for specific PTSD symptom dimensions are associated with increased asthma morbidity. Methods Participants underwent a Structured Clinical Interview for Diagnostic and Statistical Manual to assess presence of PTSD following DSM-IV criteria during in-person interviews between December 2013 and April 2015. We defined sub-threshold PTSD as meeting criteria for two of three symptom dimensions: re-experiencing, avoidance, or hyper-arousal...
December 1, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27903561/keeping-weight-off-study-protocol-of-an-rct-to-investigate-brain-changes-associated-with-mindfulness-based-stress-reduction
#5
Carl Fulwiler, Julia A Siegel, Jeroan Allison, Milagros C Rosal, Judson Brewer, Jean A King
INTRODUCTION: Obesity is a growing epidemic fuelled by unhealthy behaviours and associated with significant comorbidities and financial costs. While behavioural interventions produce clinically meaningful weight loss, weight loss maintenance is challenging. This may partially be due to failure to target stress and emotional reactivity. Mindfulness-based stress reduction (MBSR) reduces stress and emotional reactivity and may be a useful tool for behaviour change maintenance. This study seeks to provide a mechanistic understanding for clinical trials of the benefits of MBSR for weight loss maintenance by examining changes in functional connectivity (FC) and the association of these changes with clinical outcomes...
November 30, 2016: BMJ Open
https://www.readbyqxmd.com/read/27899710/quantifying-and-exploring-camouflaging-in-men-and-women-with-autism
#6
Meng-Chuan Lai, Michael V Lombardo, Amber Nv Ruigrok, Bhismadev Chakrabarti, Bonnie Auyeung, Peter Szatmari, Francesca Happé, Simon Baron-Cohen
Autobiographical descriptions and clinician observations suggest that some individuals with autism, particularly females, 'camouflage' their social communication difficulties, which may require considerable cognitive effort and lead to increased stress, anxiety and depression. Using data from 60 age- and IQ-matched men and women with autism (without intellectual disability), we operationalized camouflaging in adults with autism for the first time as the quantitative discrepancy between the person's 'external' behavioural presentation in social-interpersonal contexts (measured by the Autism Diagnostic Observation Schedule) and the person's 'internal' status (dispositional traits measured by the Autism Spectrum Quotient and social cognitive capability measured by the 'Reading the Mind in the Eyes' Test)...
November 29, 2016: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/27899398/feasibility-qualitative-findings-and-satisfaction-of-a-brief-tai-chi-mind-body-programme-for-veterans-with-post-traumatic-stress-symptoms
#7
Barbara L Niles, DeAnna L Mori, Craig P Polizzi, Anica Pless Kaiser, Annie M Ledoux, Chenchen Wang
OBJECTIVE: To examine feasibility, qualitative feedback and satisfaction associated with a 4-session introduction to Tai Chi for veterans with post-traumatic stress symptoms. DESIGN: We observed and reported recruitment and retention rates, participant characteristics, adherence, and satisfaction across 2 cohorts. We also examined qualitative feedback provided by questionnaires, focus groups and individual interviews. MAIN OUTCOME MEASURES: Rates of recruitment and retention, focus group and individual feedback interviews, self-reported satisfaction...
November 29, 2016: BMJ Open
https://www.readbyqxmd.com/read/27898147/existentiell-kris-i-livets-slutskede-f%C3%A3-rst%C3%A3-rker-de-fysiska-symtomen-minskad-%C3%A3-ngest-och-k%C3%A3-nsla-av-gemenskap-kan-minska-upplevelsen-av-sm%C3%A3-rta
#8
Peter Strang
Existential anxiety might reinforce bodily symptoms All crises have existential elements, but the crisis will transform to a predominantly existential crisis, when the dying person is no longer shielded from stressful thoughts about death, meaninglessness, existential loneliness and unsolved guilt issues. The suffering is not merely on an existential level, as the connection between body and mind is strong and existential anxiety might reinforce bodily symptoms, e.g. pain. In this article, the influence of death anxiety and loneliness is discussed in relation to pain treatment in palliative care...
November 22, 2016: Läkartidningen
https://www.readbyqxmd.com/read/27895218/a-new-approach-to-identify-high-burnout-medical-staffs-by-kernel-k-means-cluster-analysis-in-a-regional-teaching-hospital-in-taiwan
#9
Yii-Ching Lee, Shian-Chang Huang, Chih-Hsuan Huang, Hsin-Hung Wu
This study uses kernel k-means cluster analysis to identify medical staffs with high burnout. The data collected in October to November 2014 are from the emotional exhaustion dimension of the Chinese version of Safety Attitudes Questionnaire in a regional teaching hospital in Taiwan. The number of effective questionnaires including the entire staffs such as physicians, nurses, technicians, pharmacists, medical administrators, and respiratory therapists is 680. The results show that 8 clusters are generated by kernel k-means method...
2016: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/27894461/does-mindfulness-based-cognitive-therapy-benefit-all-people-with-diabetes-and-comorbid-emotional-complaints-equally-moderators-in-the-diamind-trial
#10
Ivan Nyklíček, Jenny van Son, Victor J Pop, Johan Denollet, François Pouwer
OBJECTIVES: Research has shown the effectiveness of mindfulness-based interventions for a variety of emotional problems in different samples, but it is unknown which factors influence this effectiveness. Therefore, the aim of the current study was: which factors (demographic, personality, and baseline levels of mindfulness skills) moderate the effectiveness of Mindfulness-Based Cognitive Therapy (MBCT)? METHODS: Outpatients with diabetes (type 1 or type 2; N=139) and an elevated level of emotional distress participated in the Diabetes and Mindfulness (DiaMind) trial...
December 2016: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/27894358/attentional-and-affective-consequences-of-technology-supported-mindfulness-training-a-randomised-active-control-efficacy-trial
#11
Sheffy Bhayee, Patricia Tomaszewski, Daniel H Lee, Graeme Moffat, Lou Pino, Sylvain Moreno, Norman A S Farb
BACKGROUND: Mindfulness training (MT) programs represent an approach to attention training with well-validated mental health benefits. However, research supporting MT efficacy is based predominantly on weekly-meeting, facilitator-led, group-intervention formats. It is unknown whether participants might benefit from neurofeedback-assisted, technology-supported MT (N-tsMT), in which meditation is delivered individually, without the need for a facilitator, travel to a training site, or the presence of a supportive group environment...
November 29, 2016: BMC Psychology
https://www.readbyqxmd.com/read/27893234/mindful-parenting-predicts-mothers-and-infants-hypothalamic-pituitary-adrenal-activity-during-a-dyadic-stressor
#12
Heidemarie K Laurent, Larissa G Duncan, April Lightcap, Faaiza Khan
Mindfulness in the parenting relationship has been proposed to help both parents and children better regulate stress, though this has not yet been shown at the physiological level. In this study, we tested relations between maternal mindfulness in parenting and both mothers' and their infants' hypothalamic-pituitary-adrenal (HPA) axis activity during a dyadic stressor 3 months later. Participants were 73 mother-infant dyads from a larger longitudinal study. At 3 months postpartum, mothers completed self-report measures of general dispositional mindfulness and parenting-specific mindfulness, as well as stressful life events...
November 28, 2016: Developmental Psychology
https://www.readbyqxmd.com/read/27891137/a-user-s-view-of-the-parameters-derived-from-the-induction-curves-of-maximal-chlorophyll-a-fluorescence-perspectives-for-analyzing-stress
#13
Julie Ripoll, Nadia Bertin, Luc P R Bidel, Laurent Urban
Analysis of the fast kinetics of the induction curve of maximal fluorescence represents a relatively recent development for chlorophyll a fluorescence measurements. The parameters of the so-called JIP-test are exploited by an increasingly large community of users to assess plant stress and its consequences. We provide here evidence that these parameters are capable to distinguish between stresses of different natures or intensities, and between stressed plants of different genetic background or at different developmental stages at the time of stress...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27891085/pain-perception-can-be-modulated-by-mindfulness-training-a-resting-state-fmri-study
#14
I-Wen Su, Fang-Wei Wu, Keng-Chen Liang, Kai-Yuan Cheng, Sung-Tsang Hsieh, Wei-Zen Sun, Tai-Li Chou
The multi-dimensional nature of pain renders difficult a holistic understanding of it. The conceptual framework of pain is said to be cognitive-evaluative, in addition to being sensory-discriminative and affective-motivational. To compare participants' brain-behavior response before and after a 6-week mindfulness-based stress reduction training course on mindfulness in relation to pain modulation, three questionnaires (the Dallas Pain Questionnaire, Short Form McGill Pain Questionnaire-SFMPQ, and Kentucky Inventory of Mindfulness) as well as resting-state functional magnetic resonance imaging were administered to participants, divided into a pain-afflicted group (N = 18) and a control group (N = 16)...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27890474/an-exploratory-study-of-mindfulness-based-stress-reduction-for-emotional-eating
#15
Emily Levoy, Asimina Lazaridou, Judson Brewer, Carl Fulwiler
Emotional eating is an important predictor of weight loss and weight regain after weight loss. This two part study's primary aim was to explore changes in emotional eating in a general population of individuals taking the Mindfulness Based Stress Reduction (MBSR) program, with a secondary aim to explore whether changes in mindfulness predicted changes in emotional eating. Self-reported survey data exploring these questions were collected before and after the intervention for two sequential studies (Study 1 and Study 2)...
November 24, 2016: Appetite
https://www.readbyqxmd.com/read/27889445/mindfulness-training-for-health-profession-students-the-effect-of-mindfulness-training-on-psychological-well-being-learning-and-clinical-performance-of-health-professional-students-a-systematic-review-of-randomized-and-non-randomized-controlled-trials
#16
REVIEW
Janet McConville, Rachael McAleer, Andrew Hahne
BACKGROUND: High levels of stress have been identified in medical students and increasingly in other health profession student population groups. As stress can affect psychological well-being and interfere with learning and clinical performance, there is a clear argument for universities to include health professional student well-being as an outcome in core curriculum. Mindfulness training is a potential construct to manage stress and enhance academic success. OBJECTIVES: The aims of this systematic review were to assess the effectiveness of mindfulness training in medical and other health professional student population groups and to compare the effectiveness of the different mindfulness-based programs...
October 24, 2016: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/27887679/-mindfulness-based-interventions-in-obsessive-compulsive-disorder-mechanisms-of-action-and-presentation-of-a-pilot-study
#17
M Gasnier, A Pelissolo, G Bondolfi, S Pelissolo, M Tomba, L Mallet, K N'diaye
Obsessive-compulsive disorder (OCD) is a frequent and severe disease, potentially inducing a major impairment for the patient and burden for their family. Recent research in psychiatry and neuroscience have led to better comprehension of the disease's mechanisms and helped to improve its treatment. However, a large proportion of patients have refractory symptoms, including for traditional cognitive and behavioral therapy by exposure and response prevention (ERP), leading clinicians to look for new treatments...
November 22, 2016: L'Encéphale
https://www.readbyqxmd.com/read/27882630/workplace-stress-burnout-and-coping-a-qualitative-study-of-the-experiences-of-australian-disability-support-workers
#18
Megan J Judd, Kate P Dorozenko, Lauren J Breen
Disability support workers (DSWs) are the backbone of contemporary disability support services and the interface through which disability philosophies and policies are translated into practical action. DSWs often experience workplace stress and burnout, resulting in a high turnover rate of employees within the non-professional disability service workforce. The full implementation of the National Disability Insurance Scheme in Australia is set to intensify the current challenges of attracting and retaining DSWs, as the role becomes characterised by greater demands, ambiguity and conflict...
November 23, 2016: Health & Social Care in the Community
https://www.readbyqxmd.com/read/27870432/sex-and-stress-men-and-women-show-different-cortisol-responses-to-psychological-stress-induced-by-the-trier-social-stress-test-and-the-iowa-singing-social-stress-test
#19
Alaine E Reschke-Hernández, Katrina L Okerstrom, Angela Bowles Edwards, Daniel Tranel
Acute psychological stress affects each of us in our daily lives and is increasingly a topic of discussion for its role in mental illness, aging, cognition, and overall health. A better understanding of how such stress affects the body and mind could contribute to the development of more effective clinical interventions and prevention practices. Over the past 3 decades, the Trier Social Stress Test (TSST) has been widely used to induce acute stress in a laboratory setting based on the principles of social evaluative threat, namely, a judged speech-making task...
January 2, 2017: Journal of Neuroscience Research
https://www.readbyqxmd.com/read/27868176/-mindfulness-training-for-psychiatrists-in-residency-a-pilot-study
#20
H J R Hoenders, S H Booij, H Knegtering, H van den Brink
Medical students and psychiatrists in residency run a high risk for burnout. Furthermore, while at medical school, students seem to experience a reduction in empathy; this seems to be linked to a high level of stress. Interventions based on mindfulness training appear to reduce stress and increase empathy in medical students. Trainees in psychiatric residency might also benefit from mindfulness training.<br/> AIM: To assess the effects that a mindfulness course has on perceived stress and empathy in psychiatrists in residency...
2016: Tijdschrift Voor Psychiatrie
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