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https://www.readbyqxmd.com/read/29052951/basic-self-disturbance-neurocognition-and-metacognition-a-pilot-study-among-help-seeking-adolescents-with-and-without-attenuated-psychosis-syndrome
#1
Dan Koren, Ravit Scheyer, Noa Reznik, Merav Adres, Alan Apter, Josef Parnas, Larry J Seidman
AIM: The goal of this pilot study was to assess the association between basic self-disturbance (SD) and deficits in neurocognitive and metacognitive functioning among help-seeking adolescents with and without attenuated psychosis syndrome (APS). METHODS: Sixty-one non-psychotic, help-seeking adolescents (age 13-18) were assessed with the examination of anomalous self-experience, the structured interview for prodromal syndromes and a new metacognitive approach to neurocognitive assessment applied to two non-social (executive functions and verbal memory) and two social (theory of mind and emotion recognition) domains...
October 20, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29051700/adolescent-sex-differences-in-response-to-a-mindfulness-intervention-a-call-for-research
#2
Karen Bluth, Patricia N E Roberson, Susan S Girdler
Research on mindfulness interventions with adolescents has burgeoned over the last ten years, and findings have demonstrated increases in overall emotional wellbeing post-intervention. However, little is known about the differences between males and females in response to mindfulness interventions in this age group. In the present study we examine sex differences in outcomes of physiological stress markers during the Trier Social Stress Test (TSST) and emotional wellbeing measures before and after a mindfulness intervention (N = 15) with 10 female and 5 male adolescents...
July 2017: Journal of Child and Family Studies
https://www.readbyqxmd.com/read/29045126/characterization-of-three-druggable-hotspots-in-the-aurora-a-tpx2-interaction-using-biochemical-biophysical-and-fragment-based-approaches
#3
Patrick J McIntyre, Patrick M Collins, Lukáš Vrzal, Kristian Birchall, Laurence H Arnold, Chido Mpamhanga, Peter J Coombs, Selena G Burgess, Mark W Richards, Anja Winter, Václav Veverka, Frank von Delft, Andy Merritt, Richard Bayliss
The mitotic kinase Aurora-A and its partner protein TPX2 (Targeting Protein for Xenopus kinesin-like protein 2), are overexpressed in cancers and it has been proposed that they work together as an oncogenic holoenzyme. TPX2 is responsible for activating Aurora-A during mitosis, ensuring proper cell division. Disruption of the interface with TPX2 is therefore a potential target for novel anti-cancer drugs that exploit the increased sensitivity of cancer cells to mitotic stress. Here, we investigate the interface using co-precipitation assays and isothermal titration calorimetry to quantify the energetic contribution of individual residues of TPX2...
October 18, 2017: ACS Chemical Biology
https://www.readbyqxmd.com/read/29040891/acceptance-lowers-stress-reactivity-dismantling-mindfulness-training-in-a-randomized-controlled-trial
#4
Emily K Lindsay, Shinzen Young, Joshua M Smyth, Kirk Warren Brown, J David Creswell
OBJECTIVE: Mindfulness interventions, which train practitioners to monitor their present-moment experience with a lens of acceptance, are known to buffer stress reactivity. Little is known about the active mechanisms driving these effects. We theorize that acceptance is a critical emotion regulation mechanism underlying mindfulness stress reduction effects. METHOD: In this three-arm parallel trial, mindfulness components were dismantled into three structurally equivalent 15-lesson smartphone-based interventions: (1) training in both monitoring and acceptance (Monitor+Accept), (2) training in monitoring only (Monitor Only), or (3) active control training (Coping control)...
October 8, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29039681/complementary-and-alternative-medicine-services-in-the-military-health-system
#5
Patricia M Herman, Melony E Sorbero, Ann C Sims-Columbia
OBJECTIVES: Surveys of military personnel indicate substantial use of complementary and alternative medicine (CAM) that possibly exceeds use in the general U.S. POPULATION: Although military treatment facilities (MTFs) are known to offer CAM, surveys do not indicate where service members receive this care. This study offers a comprehensive system-wide accounting of the types of CAM offered across the military health system (MHS), the conditions for which it is used, and its level of use...
October 17, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29037123/ultrafine-particles-exposure-reveals-the-importance-of-foxo1-notch-activation-complex-for-vascular-regeneration
#6
Kyung In Baek, Rene R Packard, Jefferey J Hsu, Arian Saffari, Zhao Ma, Anh Phuong Luu, Andrew Pietersen, Hilary Yen, Bin Ren, Yichen Ding, Constantinos Sioutas, Rongsong Li, Tzung K Hsiai
AIMS: Redox active ultrafine particles (UFP,<i> d</i> < 0.2 µm) promote vascular oxidative stress and atherosclerosis. Notch signaling is intimately involved in vascular homeostasis, in which FOXO1 acts a co-activator of the Notch activation complex. We elucidated the importance of FOXO1/Notch transcriptional activation complex to restore vascular regeneration following UFP exposure. RESULTS: In a zebrafish model of tail injury and repair, transgenic <i>Tg(fli1:GFP) </i>embryos developed vascular regeneration at 3 days post tail amputation, whereas UFP exposure impaired regeneration (<i>P</i> < 0...
October 17, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/29026290/mindfulness-training-for-psychological-stress-in-family-caregivers-of-persons-with-dementia-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#7
REVIEW
Zheng Liu, Qian-Lin Chen, Yu-Ying Sun
Caring for a relative with dementia is extremely challenging; conventional interventions may not be highly effective or easily available on some occasions. This study aimed to explore the efficacy of mindfulness training in improving stress-related outcomes in family caregivers of people with dementia using a meta-analytic review. We searched randomized controlled trials (RCT) through April 2017 from five electronic databases, and assessed the risk of bias using the Cochrane Collaboration tool. Seven RCTs were included in our review...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29025117/preliminary-investigation-of-workplace-provided-compressed-mindfulness-based-stress-reduction-with-pediatric-medical-social-workers
#8
Kelly Trowbridge, Lisa Mische Lawson, Stephanie Andrews, Jodi Pecora, Sabra Boyd
Mindfulness practices, including mindfulness meditation, show promise for decreasing stress among health care providers. This exploratory study investigates the feasibility of a two-day compressed mindfulness-based stress reduction (cMBSR) course provided in the hospital workplace with pediatric health care social workers. The standard course of Jon Kabat-Zinn's MBSR requires a participant commitment to eight weeks of instruction consisting of one 2.5-hour-per-week class, a single day retreat, and 45 minutes of practice for six of seven days each week...
September 8, 2017: Health & Social Work
https://www.readbyqxmd.com/read/29019964/building-iot-services-for-aging-in-place-using-standard-based-iot-platforms-and-heterogeneous-iot-products
#9
Sheik Mohammad Mostakim Fattah, Nak-Myoung Sung, Il-Yeup Ahn, Minwoo Ryu, Jaeseok Yun
An aging population and human longevity is a global trend. Many developed countries are struggling with the yearly increasing healthcare cost that dominantly affects their economy. At the same time, people living with old adults suffering from a progressive brain disorder such as Alzheimer's disease are enduring even more stress and depression than those patients while caring for them. Accordingly, seniors' ability to live independently and comfortably in their current home for as long as possible has been crucial to reduce the societal cost for caregiving and thus give family members peace of mind, called 'aging in place' (AIP)...
October 11, 2017: Sensors
https://www.readbyqxmd.com/read/29017960/upper-respiratory-tract-nociceptor-stimulation-and-stress-response-following-acute-and-repeated-cyfluthrin-inhalation-in-normal-and-pregnant-rats-physiological-rat-specific-adaptions-can-easily-be-misunderstood-as-adversities
#10
Juergen Pauluhn
This paper reviews the results from past regulatory and mechanistic inhalation studies in rats with the type II pyrethroid Cyfluthrin. Apart from many chemical irritants, Cyfluthrin was shown to be a neuroexcitatory agent without any inherent tissue-destructive or irritant property. Thus, any Cyfluthrin-induced neuroexcitatory afferent sensory stimulus from peripheral nociceptors in the upper respiratory tract is likely to be perceived as a transient stimulus triggering annoyance and/or avoidance by both rats and humans...
October 7, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28994478/treatment-of-developmental-stress-disorder-mind-body-and-brain-analysis-and-pharmacology-coupled
#11
Joseph McFadden
The schism between psychiatry, psychology and analysis, while long present, has widened even more in the past half-century with the advances in psychopharmacology. With the advances in electronic brain imaging, particularly in developmental and post-traumatic stress disorders, there has emerged both an understanding of brain changes resulting from severe, chronic stress and an ability to target brain chemistry in ways that can relieve clinical symptomatology. The use of alpha-1 adrenergic brain receptor antagonists decreases many of the manifestations of PTSD...
November 2017: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/28993747/the-use-of-virtual-reality-facilitates-dialectical-behavior-therapy%C3%A2-observing-sounds-and-visuals-mindfulness-skills-training-exercises-for-a-latino-patient-with-severe-burns-a-case-study
#12
Jocelyn Gomez, Hunter G Hoffman, Steven L Bistricky, Miriam Gonzalez, Laura Rosenberg, Mariana Sampaio, Azucena Garcia-Palacios, Maria V Navarro-Haro, Wadee Alhalabi, Marta Rosenberg, Walter J Meyer, Marsha M Linehan
Sustaining a burn injury increases an individual's risk of developing psychological problems such as generalized anxiety, negative emotions, depression, acute stress disorder, or post-traumatic stress disorder. Despite the growing use of Dialectical Behavioral Therapy® (DBT®) by clinical psychologists, to date, there are no published studies using standard DBT® or DBT® skills learning for severe burn patients. The current study explored the feasibility and clinical potential of using Immersive Virtual Reality (VR) enhanced DBT® mindfulness skills training to reduce negative emotions and increase positive emotions of a patient with severe burn injuries...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28990394/striving-for-positive-aging-among-chinese-older-people-effects-of-life-stress-and-control-beliefs-in-a-longitudinal-study
#13
Luo Lu, Shu-Fang Kao
We examined effects of life stress and control beliefs on a constellation of subjective indicators of well-being for older people, including meaning in life, happiness, peace of mind, and positive aging perception. The Chinese cultural background provided the sociocultural milieu for the present study. In a longitudinal study, 301 older Chinese adults completed a questionnaire survey twice, 6 months apart. Regression analyses found that stress caused by major life-changing events (acute) and financial hardship (chronic) were consistent negative predictors of all well-being indicators...
January 1, 2017: International Journal of Aging & Human Development
https://www.readbyqxmd.com/read/28990206/child-maltreatment-and-eating-disorders-among-men-and-women-in-adulthood-results-from-a-nationally-representative-united-states-sample
#14
Tracie O Afifi, Jitender Sareen, Janique Fortier, Tamara Taillieu, Sarah Turner, Kristene Cheung, Christine A Henriksen
OBJECTIVE: Child maltreatment is associated with an increased likelihood of having mood disorders, anxiety disorders, post-traumatic stress disorder, substance use disorders, and personality disorders, but far less is known about eating disorders. The objective of the current study was to examine the associations between child maltreatment, including harsh physical punishment, physical abuse, sexual abuse, emotional abuse, emotional neglect, physical neglect, and exposure to intimate partner violence, and eating disorders in adulthood among men and women...
October 9, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28990190/a-randomized-waitlist-control-community-study-of-social-cognition-and-interaction-training-for-people-with-schizophrenia
#15
Anne Gordon, Penelope J Davis, Susan Patterson, Christopher A Pepping, James G Scott, Kerri Salter, Melissa Connell
OBJECTIVE: Social Cognition and Interaction Training (SCIT) has demonstrated effectiveness in improving social cognition and functioning of people with schizophrenia. This pilot study examines the acceptability, feasibility, and effectiveness of SCIT with individuals who have schizophrenia-spectrum disorders and are receiving care through a public mental health service. METHOD: In a pragmatic randomized waitlist controlled trial, 36 participants (aged 19-55 years) with a schizophrenia spectrum disorder were randomly allocated to SCIT or treatment as usual (TAU)...
October 9, 2017: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28989553/a-randomized-controlled-pilot-intervention-study-of-a-mindfulness-based-self-leadership-training-mbslt-on-stress-and-performance
#16
Juliane Sampl, Thomas Maran, Marco R Furtner
The present randomized pilot intervention study examines the effects of a mindfulness-based self-leadership training (MBSLT) specifically developed for academic achievement situations. Both mindfulness and self-leadership have a strong self-regulatory focus and are helpful in terms of stress resilience and performance enhancements. Based on several theoretical points of contact and a specific interplay between mindfulness and self-leadership, the authors developed an innovative intervention program that improves mood as well as performance in a real academic setting...
2017: Mindfulness
https://www.readbyqxmd.com/read/28989549/the-effectiveness-of-mindfulness-based-stress-reduction-on-psychological-distress-and-cognitive-functioning-in-patients-with-multiple-sclerosis-a-pilot-study
#17
Roos J Blankespoor, Melanie P J Schellekens, Sandra H Vos, Anne E M Speckens, Brigit A de Jong
Patients with multiple sclerosis (MS) often suffer from psychological distress and cognitive dysfunctioning. These factors negatively impact the health-related quality of life. Only recently behavioral therapeutic approaches are being used to treat psychological distress in MS. The aim of the present pilot study was not only to investigate the effectiveness of mindfulness-based stress reduction (MBSR) on psychological distress but also to explore whether it can improve cognitive functioning among patients with MS...
2017: Mindfulness
https://www.readbyqxmd.com/read/28989548/mindful-with-your-baby-feasibility-acceptability-and-effects-of-a-mindful-parenting-group-training-for-mothers-and-their-babies-in-a-mental-health-context
#18
Eva S Potharst, Evin Aktar, Marja Rexwinkel, Margo Rigterink, Susan M Bögels
Many mothers experience difficulties after the birth of a baby. Mindful parenting may have benefits for mothers and babies, because it can help mothers regulate stress, and be more attentive towards themselves and their babies, which may have positive effects on their responsivity. This study examined the effectiveness of Mindful with your baby, an 8-week mindful parenting group training for mothers with their babies. The presence of the babies provides on-the-spot practicing opportunities and facilitates generalization of what is learned...
2017: Mindfulness
https://www.readbyqxmd.com/read/28989547/teaching-mindfulness-to-teachers-a-systematic-review-and-narrative-synthesis
#19
REVIEW
Lisa-Marie Emerson, Anna Leyland, Kristian Hudson, Georgina Rowse, Pam Hanley, Siobhan Hugh-Jones
School teachers report high levels of stress which impact on their engagement with pupils and effectiveness as a teacher. Early intervention or prevention approaches may support teachers to develop positive coping and reduce the experience and impact of stress. This article reviews research on one such approach: mindfulness-based interventions (MBIs) for school teachers. A systematic review and narrative synthesis were conducted for quantitative and qualitative studies that report the effects of MBIs for teachers of children aged 5-18 years on symptoms of stress and emotion regulation and self-efficacy...
2017: Mindfulness
https://www.readbyqxmd.com/read/28987079/effectiveness-of-biofield-therapy-for-patients-diagnosed-with-fibromyalgia
#20
Fernando Sarmento, Hideaki Tanaka, Eduarda Cordeiro, Kiyoshi Suzuki
Context • Fibromyalgia (FM) is a disorder with an unknown etiology; symptoms include physical and psychological stress, widespread chronic pain, insomnia, and depression. Mind-body medicine and aerobic exercise have shown positive effects for symptom control. Several studies have reported positive effects for biofield therapy for FM, but when other studies have compared the treatment with a sham control, they have not found those beneficial effects. Objective • The study intended to examine the effects of a biofield therapy called Okada purifying therapy on patients' FM symptoms...
October 2, 2017: Alternative Therapies in Health and Medicine
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