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https://www.readbyqxmd.com/read/28735388/epigenetics-and-rna-processing-connections-to-drought-salt-and-aba
#1
Min May Wong, Geeng Loo Chong, Paul E Verslues
There have been great research advances in epigenetics, RNA splicing, and mRNA processing over recent years. In parallel, there have been many advances in abiotic stress and Abscisic Acid (ABA) signaling. Here we overview studies that have examined stress-induced changes in the epigenome and RNA processing as well as cases where disrupting these processes changes the plant response to abiotic stress. We also highlight some examples where specific connections of stress or ABA signaling to epigenetics or RNA processing have been found...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28727625/decreasing-stress-and-burnout-in-nurses-efficacy-of-blended-learning-with-stress-management-and-resilience-training-program
#2
Donna L Magtibay, Sherry S Chesak, Kevin Coughlin, Amit Sood
OBJECTIVE: The study's purpose was to assess efficacy of blended learning to decrease stress and burnout among nurses through use of the Stress Management and Resiliency Training (SMART) program. BACKGROUND: Job-related stress in nurses leads to high rates of burnout, compromises patient care, and costs US healthcare organizations billions of dollars annually. Many mindfulness and resiliency programs are taught in a format that limits nurses' attendance. METHODS: Consistent with blended learning, participants chose the format that met their learning styles and goals; Web-based, independent reading, facilitated discussions...
July 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28722002/report-of-occurrence-and-endodontic-management-of-three-rooted-maxillary-first-and-second-premolars-in-the-same-individual
#3
Kothandaraman Sathyanarayanan, Manali Ramakrishnan Srinivasan, Sundaresan Balagopal, Lingeswaran Poornima
Anatomical variations should be kept in mind in clinical and carefully looked for in radiographic evaluation during endodontic treatment of maxillary premolars. These teeth have highly variable root canal morphology. Although three separate roots in the maxillary first premolars have been reported, it is a rarity to find both the first and second premolars possessing three separate roots. This case report describes the diagnosis and endodontic management of maxillary first and second premolars with three canals and three separate roots...
May 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28721742/mindfulness-based-stress-reduction-in-middle-aged-and-older-adults-with-memory-complaints-a-mixed-methods-study
#4
Lotte Berk, Rafke Hotterbeekx, Jim van Os, Martin van Boxtel
OBJECTIVES: In a rapidly aging world population, an increasingly large group faces age-related decline in cognitive functioning. Cognitive complaints of older adults are often related to worries and concerns associated with age-related functional decline. Mindfulness-Based Stress Reduction (MBSR) can successfully target stress, worry and ruminative thinking, but the applicability of this method in middle-aged and older adults with memory complaints is unclear. METHOD: Patients of a university hospital memory clinic (n = 13), aged 45-85 years, with memory complaints but no diagnosis of cognitive disorder, participated in a standard 8-week MBSR program, consisting of weekly group meetings and a one-day silent retreat...
July 19, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28721461/influence-of-adjuvant-detached-mindfulness-and-stress-management-training-compared-to-pharmacologic-treatment-in-primiparae-with-postpartum-depression
#5
Mohammad Ahmadpanah, Marzieh Nazaribadie, Elham Aghaei, Ali Ghaleiha, Azade Bakhtiari, Mohammad Haghighi, Dena Sadeghi Bahmani, Amineh Akhondi, Hafez Bajoghli, Leila Jahangard, Edith Holsboer-Trachsler, Serge Brand
Ten to 15% of mothers experience postpartum depression (PPD). If untreated, PPD may negatively affect mothers' and infants' mental health in the long term. Accordingly, effective treatments are required. In the present study, we investigated the effect of detached mindfulness (DM) and stress management training (SMT) as adjuvants, compared to pharmacologic treatment only, on symptoms of depression in women with PPD. Forty-five primiparae (mean age: M = 24.5 years) with diagnosed PPD and treated with an SSRI (citalopram; CIT) took part in the study...
July 18, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/28712420/the-role-of-trait-mindfulness-in-quality-of-life-and-asthma-control-among-adolescents-with-asthma
#6
Linda Cillessen, Monique O van de Ven, Johan C Karremans
OBJECTIVE: The current study focused on the role of trait mindfulness in asthma-related quality of life (QoL) and asthma control in adolescent asthma patients. Furthermore, potential underlying mechanisms (general and asthma-specific stress) of this relationship were investigated. METHODS: In this cross-sectional study, questionnaire data of 94 adolescents with asthma that were prescribed daily asthma medication were included. Two Structural Equation Models (SEMs), a direct model and an indirect model, were tested...
August 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28707471/one-step-identification-of-antibody-degradation-pathways-using-fluorescence-signatures-generated-by-cross-reactive-dna-based-arrays
#7
Shunsuke Tomita, Ayumi Matsuda, Suguru Nishinami, Ryoji Kurita, Kentaro Shiraki
Therapeutic antibodies are prone to degradation via a variety of pathways during each stage of the manufacturing process. Hence, a low-cost, rapid, and broadly applicable tool that is able to identify when and how antibodies degrade would be highly desirable to control the quality of therapeutic antibody products. With this goal in mind, we have developed signature-based sensing system to discriminate differently degraded therapeutic antibodies. The use of arrays consisting of conjugates between nanographene oxide and fluorophore-modified single-stranded DNAs under acidic pH conditions generated unique fluorescence signatures for each state of the antibodies...
July 18, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28707425/experiential-acceptance-and-trait-mindfulness-as-predictors-of-analogue-post-traumatic-stress
#8
Paul A Boelen, Lonneke I M Lenferink
OBJECTIVES: Experiential acceptance and trait-mindfulness are associated with post-traumatic stress disorder (PTSD) after traumatic events. This study was a preliminary attempt to examine (1) associations of experiential acceptance and trait-mindfulness with post-traumatic stress (PTS) associated with negative, but not necessarily traumatizing, life events ('analogue' PTS), (2) the role of these variables in the context of neuroticism as well as worry and rumination - two other regulatory strategies associated with PTS, and (3) the impact of pre-trauma tendencies towards experiential acceptance and mindfulness on analogue PTS...
July 14, 2017: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/28702717/mindfulness-based-stress-reduction-and-group-support-decrease-stress-in-adolescents-with-cardiac-diagnoses-a-randomized-two-group-study
#9
Vicki A Freedenberg, Pamela S Hinds, Erika Friedmann
Adolescents with cardiac diagnoses face unique challenges that can cause psychosocial distress. This study compares a Mindfulness-Based Stress Reduction (MBSR) program to a video online support group for adolescents with cardiac diagnoses. MBSR is a structured psycho-educational program which includes yoga, meditation, cognitive restructuring, and group support. A published feasibility study by our group showed significant reduction in anxiety following this intervention. Participants were randomized to MBSR or video online support group, and completed measures of anxiety, depression, illness-related stress, and coping pre- and post-6-session interventions...
July 12, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28701943/aberrant-long-range-temporal-correlations-in-depression-are-attenuated-after-psychological-treatment
#10
Matti Gärtner, Mona Irrmischer, Emilia Winnebeck, Maria Fissler, Julia M Huntenburg, Titus A Schroeter, Malek Bajbouj, Klaus Linkenkaer-Hansen, Vadim V Nikulin, Thorsten Barnhofer
The spontaneous oscillatory activity in the human brain shows long-range temporal correlations (LRTC) that extend over time scales of seconds to minutes. Previous research has demonstrated aberrant LRTC in depressed patients; however, it is unknown whether the neuronal dynamics normalize after psychological treatment. In this study, we recorded EEG during eyes-closed rest in depressed patients (N = 71) and healthy controls (N = 25), and investigated the temporal dynamics in depressed patients at baseline, and after attending either a brief mindfulness training or a stress reduction training...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28694675/changes-in-psychosocial-well-being-after-mindfulness-based-stress-reduction-a-prospective-cohort-study
#11
Renee J Hill, Lindsey C McKernan, Li Wang, Rogelio A Coronado
Objectives: The primary purpose of the current study was to assess the effects of a mindfulness-based stress reduction (MBSR) program, facilitated by non-psychologist clinicians, for improving psychosocial well-being. A secondary purpose of the current study was to explore the role of self-compassion as a potential underlying factor for improvements in emotional distress. Application of these findings to a physical therapy setting is provided. Methods: One hundred and thirty participants with a variety of medical complaints completed an eight-week MBSR program at Vanderbilt University's Osher Center for Integrative Medicine...
July 2017: Journal of Manual & Manipulative Therapy
https://www.readbyqxmd.com/read/28692014/effect-of-mindfulness-based-stress-reduction-training-on-health-care-worker-safety-a-randomized-waitlist-controlled-trial
#12
Morgan Anne Valley, Lorann Stallones
OBJECTIVE: The study assessed the impact of mindfulness training on occupational safety of hospital health care workers. METHODS: The study used a randomized waitlist-controlled trial design to test the effect of an 8-week mindfulness-based stress reduction (MBSR) course on self-reported health care worker safety outcomes, measured at baseline, postintervention, and 6 months later. RESULTS: Twenty-three hospital health care workers participated in the study (11 in immediate intervention group; 12 in waitlist control group)...
July 6, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28690665/use-of-integrative-medicine-in-the-united-states-military-health-system
#13
REVIEW
Cathaleen Madsen, Megan Vaughan, Tracey Pérez Koehlmoos
Integrative medicine (IM) is a model of care which uses both conventional and nonconventional therapies in a "whole person" approach to achieve optimum mental, physical, emotional, spiritual, and environmental health, and is increasingly popular among patients and providers seeking to relieve chronic or multifactorial conditions. The US Department of Defense (DoD) shows particular interest in and usage of IM for managing chronic conditions including the signature "polytrauma triad" of chronic pain, traumatic brain injury (TBI), and posttraumatic stress disorder (PTSD) among its beneficiaries in the Military Health System (MHS)...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28687263/brief-mindfulness-practices-for-healthcare-providers-a-systematic-literature-review
#14
REVIEW
Heather Gilmartin, Anupama Goyal, Mary C Hamati, Jason Mann, Sanjay Saint, Vineet Chopra
Mindfulness practice, where an individual maintains openness, patience, and acceptance, while focusing attention on a situation in a non-judgmental way, can improve symptoms of anxiety, burnout, and depression. The practice is relevant for healthcare providers; however, the time commitment is a barrier to practice. For this reason, brief mindfulness interventions (e.g. ≤ four hours) are being introduced. We systematically reviewed the literature from inception to January 2017 regarding the effects of brief mindfulness interventions on provider well-being and behavior...
July 4, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28686822/mindfulness-based-stress-reduction-for-older-adults-with-stress-disorders-and-neurocognitive-difficulties-a-randomized-controlled-trial
#15
Julie Loebach Wetherell, Tamara Hershey, Steven Hickman, Susan R Tate, David Dixon, Emily S Bower, Eric J Lenze
OBJECTIVE: To determine whether neurocognitive performance and clinical outcomes can be enhanced by a mindfulness intervention in older adults with stress disorders and cognitive complaints. To explore decreased hypothalamic-pituitary-adrenal (HPA) axis activity as a possible mechanism. METHODS: 103 adults aged 65 years or older with an anxiety or depressive disorder (diagnosed according to DSM-IV criteria) and subjective neurocognitive difficulties were recruited in St...
July 5, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28686520/mindfulness-based-interventions-for-women-with-breast-cancer-an-updated-systematic-review-and-meta-analysis
#16
Heidemarie Haller, María M Winkler, Petra Klose, Gustav Dobos, Sherko Kümmel, Holger Cramer
BACKGROUND: The aim of this meta-analysis was to systematically update the evidence for mindfulness-based stress reduction (MBSR) and mindfulness-based cognitive therapy (MBCT) in women with breast cancer. MATERIAL AND METHODS: In October 2016, PubMed, Scopus, and Central were searched for randomized controlled trials on MBSR/MBCT in breast cancer patients. The primary outcome was health-related quality of life. Secondary outcomes were fatigue, sleep stress, depression, anxiety, and safety...
July 7, 2017: Acta Oncologica
https://www.readbyqxmd.com/read/28686006/mindfulness-based-stress-reduction-in-women-with-overweight-or-obesity-a-randomized-clinical-trial
#17
Nazia Raja-Khan, Katrina Agito, Julie Shah, Christy M Stetter, Theresa S Gustafson, Holly Socolow, Allen R Kunselman, Diane K Reibel, Richard S Legro
OBJECTIVE: To evaluate the feasibility and cardiometabolic effects of mindfulness-based stress reduction (MBSR) in women with overweight or obesity. METHODS: Eighty-six women with BMI ≥ 25 kg/m(2) were randomized to 8 weeks of MBSR or health education and followed for 16 weeks. The primary outcome was the Toronto Mindfulness Scale. Secondary outcomes included the Perceived Stress Scale-10, fasting glucose, and blood pressure. RESULTS: Compared to health education, the MBSR group demonstrated significantly improved mindfulness at 8 weeks (mean change from baseline, 4...
July 7, 2017: Obesity
https://www.readbyqxmd.com/read/28683799/mindfulness-and-compassion-oriented-practices-at-work-reduce-distress-and-enhance-self-care-of-palliative-care-teams-a-mixed-method-evaluation-of-an-on-the-job-program
#18
Claudia L Orellana-Rios, Lukas Radbruch, Martina Kern, Yesche U Regel, Andreas Anton, Shane Sinclair, Stefan Schmidt
BACKGROUND: Maintaining a sense of self-care while providing patient centered care, can be difficult for practitioners in palliative medicine. We aimed to pilot an "on the job" mindfulness and compassion-oriented meditation training for interdisciplinary teams designed to reduce distress, foster resilience and strengthen a prosocial motivation in the clinical encounter. METHODS: Our objective was to explore the feasibility and effectiveness of this newly developed training...
July 6, 2017: BMC Palliative Care
https://www.readbyqxmd.com/read/28681962/systematic-review-of-management-of-chronic-pain-after-surgery
#19
REVIEW
V Wylde, J Dennis, A D Beswick, J Bruce, C Eccleston, N Howells, T J Peters, R Gooberman-Hill
BACKGROUND: Pain present for at least 3 months after a surgical procedure is considered chronic postsurgical pain (CPSP) and affects 10-50 per cent of patients. Interventions for CPSP may focus on the underlying condition that indicated surgery, the aetiology of new-onset pain or be multifactorial in recognition of the diverse causes of this pain. The aim of this systematic review was to identify RCTs of interventions for the management of CPSP, and synthesize data across treatment type to estimate their effectiveness and safety...
July 6, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28680447/a-review-of-dietary-ziziphus-jujuba-fruit-jujube-developing-health-food-supplements-for-brain-protection
#20
REVIEW
Jianping Chen, Xiaoyan Liu, Zhonggui Li, Airong Qi, Ping Yao, Zhongyu Zhou, Tina T X Dong, Karl W K Tsim
The fruits of Ziziphus jujuba, known as jujube or Chinese date, are being consumed all around the world because of their health benefits, as both food and herbal medicine. Traditionally, one of the main functions of jujube, as described in herbal medicine, is to benefit our brain by calming down the mind and improving quality of sleep. Here, the activities of jujubes on nervous system are summarized and discussed. Jujube possesses neuroprotective activities, including protecting neuronal cells against neurotoxin stress, stimulating neuronal differentiation, increasing expression of neurotrophic factors, and promoting memory and learning...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
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