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https://www.readbyqxmd.com/read/29222619/improvement-in-obstructive-sleep-apnea-after-a-tailored-behavioural-sleep%C3%A2-medicine-intervention-targeting-healthy-eating-and-physical-activity-a-randomised-controlled-trial
#1
Helena Igelström, Pernilla Åsenlöf, Margareta Emtner, Eva Lindberg
PURPOSE: The aim of the present single-centre randomised controlled trial was to assess the effect of a behavioural sleep medicine (BSM) intervention on obstructive sleep apnea (OSA) severity in patients who have been referred for new treatment with continuous positive airway pressure (CPAP). METHODS: After baseline assessment including ventilatory and anthropometric parameters, and physical activity monitoring, 86 patients who were overweight (BMI ≥ 25) and had moderate-severe OSA with apnea-hypopnea index (AHI) ≥ 15 were randomised into a control group (CG; CPAP and advice about weight loss) or an experimental group (ExpG; CPAP and BSM intervention targeting physical activity and eating behaviour)...
December 8, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29222551/neutrophil-and-t-cell-homeostasis-in-the-closed-eye
#2
Cameron K Postnikoff, Kelly K Nichols
Purpose: This study sought to examine the changes and phenotype of the tear neutrophil and T-cell populations between early eyelid closure and after a full night of sleep. Methods: Fourteen healthy participants were recruited and trained to wash the ocular surface with PBS for at-home self-collection of ocular surface and tear leukocytes following up to 1 hour of sleep and a full night of sleep (average 7 hours), on separate days. Cells were isolated, counted, and incubated with fluorescently labeled antibodies to identify neutrophils, monocytes, and T cells...
December 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29213496/effects-of-a-cognitive-training-program-and-sleep-hygiene-for-executive-functions-and-sleep-quality-in-healthy-elderly
#3
Katie Moraes de Almondes, Maria Emanuela Matos Leonardo, Ana Maria Souza Moreira
Introduction: The aging process causes changes in the sleep-wake cycle and cognition, especially executive functions. Interventions are required to minimize the impact of the losses caused by the aging process. Objective: To evaluate the effects of a cognitive training program and psychoeducation on sleep hygiene techniques for executive functions and sleep quality in healthy elderly. Methods: The participants were 41 healthy elderly randomized into four groups ([CG] control group, cognitive training group [CTG], sleep hygiene group [SHG] and cognitive training and hygiene group [THG])...
January 2017: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29208534/loss-of-cdkl5-disrupts-respiratory-function-in-mice
#4
Kun-Ze Lee, Wenlin Liao
Cyclin-dependent kinase-like 5 (CDKL5) is an X-linked gene encoding a serine-threonine kinase that is highly expressed in the central nervous system. Mutations in CDKL5 cause neurological and psychiatric symptoms, including early-onset seizures, motor dysfunction, autistic features and sleep breathing abnormalities in patients. It remains to be addressed whether loss of CDKL5 causes respiratory dysfunction in mice. Here, we examined the respiratory pattern of male Cdkl5-/y mice at 1-3 months of age during resting breathing and respiratory challenge (i...
December 2, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/29207559/tooth-wear-is-frequent-in-adult-patients-with-celiac-disease
#5
Massimo Amato, Fabiana Zingone, Mario Caggiano, Paola Iovino, Cristina Bucci, Carolina Ciacci
(1) Background: Celiac disease (CD) patients can be affected by mouth and tooth disorders, which are influenced by their gluten-free diet. The aim of our research was to evaluate the pathological conditions of the stomatognathic system observed in celiac patients on a gluten-free diet. (2) Methods: we consecutively recruited celiac patients on a gluten-free diet at our celiac center, as well as healthy volunteers. Two dentists examined all patients/controls and checked them for any mouth disorder. (3) Results: Forty-nine patients affected by celiac disease (age at test 31...
December 4, 2017: Nutrients
https://www.readbyqxmd.com/read/29206481/age-memory-loss-and-perceptions-of-dementia-in-south-asian-ethnic-minorities
#6
Clarissa M Giebel, Angela Worden, David Challis, David Jolley, Kamaldeep Singh Bhui, Ahmed Lambat, Eleni Kampanellou, Nitin Purandare
BACKGROUND: South Asian older adults are represented less frequently in mainstream mental health services or those for people with dementia. This study aimed to explore in detail the perceptions of dementia (symptoms, causes, consequences, treatments) held by South Asians and to discern how these understandings vary by age and by the self-recognition of memory problems, as these influence help-seeking behaviour. METHODS: Participants were allocated to three groups: younger adults; older adults; and older adults with subjective memory problems...
December 5, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/29200617/the-relationship-between-bruxism-sleep-quality-and-headaches-in-schoolchildren
#7
Carolina Carvalho Bortoletto, Mônica da Consolação Canuto Salgueiro, Renata Valio, Yara Dadalti Fragoso, Pamella de Barros Motta, Lara Jansiski Motta, Fernanda Yukie Kobayashi, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Alessandro Deana, Sandra Kalil Bussadori
[Purpose] Present study aimed to evaluate the relationship between sleep bruxism and headache in school children. [Subjects and Methods] This study was conducted with 103 children aged 3-6 years. The exclusion criteria were early tooth loss, dental appliance was used, physical or psychological limitations, chronic disease and continuous medication. Sleep bruxism was diagnosed based on an indication by parents of the occurrence of teeth clenching/grinding and incisor/occlusal tooth wear, following the criteria of the American Academy of Sleep Medicine...
November 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29198969/validation-of-a-touchscreen-psychomotor-vigilance-task
#8
Lucia Arsintescu, Kenji H Kato, Patrick F Cravalho, Nathan H Feick, Leland S Stone, Erin E Flynn-Evans
OBJECTIVE: The purpose of this study was to compare a psychomotor vigilance task developed for use on touchscreen devices with the original PVT-192 in conditions of acute sleep loss and circadian desynchronization. BACKGROUND: The Psychomotor Vigilance Task (PVT) is considered the gold standard fatigue detection test and is used frequently in fatigue research. With the rapid development of new technologies it is essential to develop a PVT available on different platforms such as touchscreen devices...
November 30, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29198751/diabetes-resolution-after-one-anastomosis-gastric-bypass
#9
Adam Abu-Abeid, Yonatan Lessing, Niv Pencovich, Danit Dayan, Joseph M Klausner, Subhi Abu-Abeid
BACKGROUND: Diabetes and other obesity-related diseases are a worldwide pandemic that transcends geographic borders as well as socioeconomic levels. Currently, it is well known that medical treatment alone is insufficient to ensure adequate and sustainable weight loss and co-morbidity resolution. It has been well proven that bariatric surgery can produce almost immediate resolution of diabetes and other co-morbidities as well as long-term weight loss. OBJECTIVES: Here, we present our experience with the one anastomosis gastric bypass (OAGB) in terms of weight loss and diabetes resolution with 1 year of follow-up...
November 3, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29197617/3-d-motion-capture-for-long-term-tracking-of-spontaneous-locomotor-behaviors-and-circadian-sleep-wake-rhythms-in-mouse
#10
Melissa Sourioux, Emma Bestaven, Etienne Guillaud, Sandrine Bertrand, Magali Cabanas, Lea Milan, Willy Mayo, Maurice Garret, Jean-René Cazalets
BACKGROUND: Locomotor activity provides an index of an animal's behavioral state. Here, we report a reliable and cost-effective method that allows long-term (days to months) simultaneous tracking of locomotion in mouse cohorts (here consisting of 24 animals). NEW METHOD: The technique is based on a motion capture system used mainly for human movement study. A reflective marker was placed on the head of each mouse using a surgical procedure and labeled animals were returned to their individual home cages...
November 29, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29194294/task-switching-following-24%C3%A2-h-of-total-sleep-deprivation-a-functional-mri-study
#11
Ann Nakashima, Fethi Bouak, Quan Lam, Ingrid Smith, Oshin Vartanian
Task switching is a ubiquitous feature of many human activities that involve multitasking. In addition, owing to occupational demands, many individuals are required to engage in task switching under various levels of sleep deprivation, such as those who work in military and medical contexts. Nevertheless, little is known about the effects that sleep loss has on the neural bases of task switching. To address this shortcoming, we administered a cued switching task to participants following a night of normal sleep and also following a night of total sleep deprivation - in counterbalanced order...
November 29, 2017: Neuroreport
https://www.readbyqxmd.com/read/29194205/a-protective-eye-shield-reduces-limbal-strain-and-its-variability-during-simulated-sleep-in-adults-with-glaucoma
#12
Alison Flatau, Francisco Solano, Joan L Jefferys, Christopher Damion, Harry A Quigley
PURPOSE: To determine the effect of wearing a protective eye shield (mask) on limbal strain magnitude and variability in glaucoma eyes when sleeping with 1 side of the face down (FD) against a pillow. METHODS: A prospective, randomized, interventional trial was conducted at the Wilmer Eye Institute with 36 glaucoma patients. A contact lens sensor measured limbal strain (output in equivalent millivolts) during intervals of up to 60 minutes in lateral decubitus, FD, and supine positions...
November 30, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29189700/effectiveness-of-support-groups-to-improve-the-quality-of-life-of-people-with-idiopathic-pulmonary-fibrosis-a-pre-post-test-pilot-study
#13
Daniela Magnani, Graziana Lenoci, Sara Balduzzi, Giovanna Artioli, Paola Ferri
BACKGROUND AND AIM OF THE WORK: Idiopathic Pulmonary Fibrosis (IPF) is an interstitial lung disease, which progressively leads to severe disability and death. The average survival expectancy, ranges from 3 to 5 years from diagnosis, and the available medicines do not lead to healing. The progression of IPF lead to a decline in forced vital capacity (FVC), dyspnea, cough, continuous sleep interruptions, resulting in increased fatigue and deteriorating quality of life (QOL), progressive limitation of daily life activities and social life, with repercussions on psychological and emotional well-being, aggravated by anxiety, loss of sense of self-confidence and depression...
November 30, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/29189544/is-obstructive-sleep-apnea-associated-with-progressive-glaucomatous-optic-neuropathy
#14
Swarup S Swaminathan, Amitabha S Bhakta, Wei Shi, William J Feuer, Alexandre R Abreu, Alejandro D Chediak, David S Greenfield
PURPOSE: To evaluate the relationship between obstructive sleep apnea syndrome (OSAS) and glaucoma progression, and to examine the correlation between OSAS severity and rate of visual field (VF) loss. METHODS: Patients with concurrent diagnoses of open-angle glaucoma and OSAS between 2010-2016 were identified. Enrollment criteria consisted of glaucomatous optic neuropathy and VF loss, ≥5 reliable VFs, ≥2 years of follow-up, and polysomnography (PSG) within 12 months of final VF...
November 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29186205/narcolepsy-susceptibility-gene-ccr3-modulates-sleep-wake-patterns-in-mice
#15
Hiromi Toyoda, Yoshiko Honda, Susumu Tanaka, Taku Miyagawa, Makoto Honda, Kazuki Honda, Katsushi Tokunaga, Tohru Kodama
Narcolepsy is caused by the loss of hypocretin (Hcrt) neurons and is associated with multiple genetic and environmental factors. Although abnormalities in immunity are suggested to be involved in the etiology of narcolepsy, no decisive mechanism has been established. We previously reported chemokine (C-C motif) receptor 3 (CCR3) as a novel susceptibility gene for narcolepsy. To understand the role of CCR3 in the development of narcolepsy, we investigated sleep-wake patterns of Ccr3 knockout (KO) mice. Ccr3 KO mice exhibited fragmented sleep patterns in the light phase, whereas the overall sleep structure in the dark phase did not differ between Ccr3 KO mice and wild-type (WT) littermates...
2017: PloS One
https://www.readbyqxmd.com/read/29184345/vagus-nerve-stimulation-modulates-complexity-of-heart-rate-variability-differently-during-sleep-and-wakefulness
#16
Karthi Balasubramanian, K Harikumar, Nithin Nagaraj, Sandipan Pati
Progressive loss of heart rate variability (HRV) and complexity are associated with increased risk of mortality in patients with cardiovascular disease and are a candidate marker for patients at risk of sudden cardiac death. HRV is influenced by the cardiac autonomic nervous system (ANS), although it is unclear which arm of the ANS (sympathetic or parasympathetic) needs to be perturbed to increase the complexity of HRV. In this case-control study, we have analyzed the relation between modulation of vagus nerve stimulation (VNS) and changes in complexity of HRV as a function of states of vigilance...
October 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/29183826/developmental-ethanol-induced-sleep-fragmentation-behavioral-hyperactivity-cognitive-impairment-and-parvalbumin-cell-loss-are-prevented-by-lithium-co-treatment
#17
M Lewin, M Ilina, J Betz, K Masiello, M Hui, D A Wilson, M Saito
Developmental ethanol exposure is a well-known cause of lifelong cognitive deficits, behavioral hyperactivity, emotional dysregulation, and more. In healthy adults, sleep is thought to have a critical involvement in each of these processes. Our previous work has demonstrated that some aspects of cognitive impairment in adult mice exposed at postnatal day 7 (P7) to ethanol (EtOH) correlate with slow-wave sleep (SWS) fragmentation (Wilson et al., 2016). We and others have also previously demonstrated that co-treatment with LiCl on the day of EtOH exposure prevents many of the anatomical and physiological impairments observed in adults...
November 26, 2017: Neuroscience
https://www.readbyqxmd.com/read/29181707/role-of-sex-and-the-environment-in-moderating-weight-gain-due-to-inadequate-sleep
#18
REVIEW
Jamie E Coborn, Monica M Houser, Claudio E Perez-Leighton, Jennifer A Teske
PURPOSE OF REVIEW: The growing prevalence of obesity, inadequate sleep and sleep disorders together with the negative impact of lack of sleep on overall health highlights the need for therapies targeted towards weight gain due to sleep loss. RECENT FINDINGS: Sex disparities in obesity and sleep disorders are present; yet, the role of sex is inadequately addressed and thus it is unclear whether sensitivity to sleep disruption differs between men and women. Like sex, environmental factors contribute to the development of obesity and poor sleep...
December 2017: Current Obesity Reports
https://www.readbyqxmd.com/read/29180134/learning-and-memory-are-impaired-in-the-object-recognition-task-during-metestrus-diestrus-and-after-sleep-deprivation
#19
Joshua Cordeira, Sai Saroja Kolluru, Heather Rosenblatt, Jenny Kry, Robert E Strecker, Robert W McCarley
Females are an under-represented research model and the mechanisms through which sleep loss impairs cognition are not clear. Since levels of reproductive hormones and the estrous cycle are sensitive to sleep loss and necessary for learning and memory, we hypothesized that sleep deprivation impacts learning and memory in female mice by interfering with the estrous cycle. We used the object recognition task to assess learning and memory in female mice during separate phases of the estrous cycle and after sleep loss...
November 24, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29170758/design-and-rationale-for-a-technology-based-healthy-lifestyle-intervention-in-older-adults-grieving-the-loss-of-a-spouse
#20
Sarah T Stahl, James Emanuel, Steven M Albert, Mary Amanda Dew, Richard Schulz, Gregg Robbins-Welty, Charles F Reynolds
Introduction: Experiencing the death of a spouse during late life is associated with an increased risk of developing debilitating mental health problems. Healthy lifestyle practices, such as regular exercise, healthy eating, and good sleep hygiene are promising strategies to influence the mental health and associated physical symptoms of late-life spousal bereavement. Objective: This paper describes the design and rationale of an intervention development study addressing selective and indicated prevention of depression, anxiety, and/or complicated grief disorder(s) among adults 60 years and older who are grieving the recent loss (within 8 months) of a spouse or partner...
December 2017: Contemporary Clinical Trials Communications
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