keyword
MENU ▼
Read by QxMD icon Read
search

sleep loss

keyword
https://www.readbyqxmd.com/read/29042189/dietary-disinhibition-mediates-the-relationship-between-poor-sleep-quality-and-body-weight
#1
Michelle L Blumfield, Bei Bei, Iona Z Zimberg, Sean W Cain
BACKGROUND: Inadequate sleep independently influences eating habits and weight status. However, the relationship between these three factors has not been well quantified. The objective of this study was to examine if eating behavior (i.e. dietary restraint, disinhibition and hunger) mediates the relationship between sleep and body mass index (BMI) in a large sample of American adults. METHOD: Cross-sectional data from the Nathan Kline Institute Rockland sample were assessed (n = 602; 38...
October 14, 2017: Appetite
https://www.readbyqxmd.com/read/29038203/effect-of-continuous-positive-airway-pressure-weight-loss-or-continuous-positive-airway-pressure-plus-weight-loss-on-central-hemodynamics-and-arterial-stiffness
#2
Snigdha Jain, Indira Gurubhagavatula, Raymond Townsend, Samuel T Kuna, Karen Teff, Thomas A Wadden, Jesse Chittams, Alexandra L Hanlon, Greg Maislin, Hassam Saif, Preston Broderick, Zeshan Ahmad, Allan I Pack, Julio A Chirinos
Obesity and obstructive sleep apnea tend to coexist. Little is known about the effects of obstructive sleep apnea, obesity, or their treatment on central aortic pressures and large artery stiffness. We randomized 139 adults with obesity (body mass index >30 kg/m(2)) and moderate-to-severe obstructive sleep apnea to (1) continuous positive airway pressure (CPAP) therapy (n=45), (2) weight loss (WL) therapy (n=48), or (3) combined CPAP and WL (n=46) for 24 weeks. We assessed the effect of these interventions on central pressures and carotid-femoral pulse wave velocity (a measure of large artery stiffness), measured with arterial tonometry...
October 16, 2017: Hypertension
https://www.readbyqxmd.com/read/29033864/novel-measures-to-assess-the-effects-of-partial-sleep-deprivation-on-sensory-working-and-permanent-memory
#3
Dominique Gosselin, Joseph De Koninck, Kenneth Campbell
Sleepiness has repeatedly been demonstrated to affect performance on a variety of cognitive tasks. While the effects of total sleep deprivation (TSD) have been extensively studied, acute partial sleep deprivation (PSD), a more frequent form of sleep loss, has been studied much less often. The present study examined the effects of sleep deprivation on novel tasks involving classic sensory, working, and permanent memory systems. While the tasks did implicate different memory systems, they shared a need for effortful, sustained attention to maintain successful performance...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29029348/dysregulation-of-sleep-behavioral-states-in-narcolepsy
#4
Sarah F Schoch, Esther Werth, Rositsa Poryazova, Thomas E Scammell, Christian R Baumann, Lukas L Imbach
Study Objectives: Patients with narcolepsy suffer from poor maintenance of wakefulness and fragmented night sleep, but the underlying mechanism of sleep boundary dysregulation remains little understood. The goal of this study was to quantify abnormal sleep-wake regulation in narcolepsy patients. Methods: Using a model-based approach (state space analysis), we analyzed overnight EEG recordings in ten patients with narcolepsy type 1 and age- and gender-matched healthy control subjects...
October 5, 2017: Sleep
https://www.readbyqxmd.com/read/29029309/limited-efficacy-of-caffeine-and-recovery-costs-during-and-following-5-days-of-chronic-sleep-restriction-caffeine-and-sleep-restriction
#5
Tracy Jill Doty, Christine J So, Elizabeth M Bergman, Sara K Trach, Ruthie H Ratcliffe, Angela M Yarnell, Vincent F Capaldi, James E Moon, Thomas J Balkin, Phillip J Quartana
Objectives: To investigate the effects of caffeine on psychomotor vigilance and sleepiness during sleep restriction and following subsequent recovery sleep. Methods: Participants were N=48 healthy good sleepers. All participants underwent 5 nights of sleep satiation [time-in-bed (TIB): 10 hrs], followed by 5 nights of sleep restriction (TIB: 5 hrs), and 3 nights of recovery sleep (TIB: 8 hrs) in a sleep laboratory. Caffeine (200 mg) or placebo was administered in the form of chewing gum at 0800 and 1200 hrs each day during the sleep restriction phase...
October 5, 2017: Sleep
https://www.readbyqxmd.com/read/29029302/acute-kynurenine-challenge-disrupts-sleep-wake-architecture-and-impairs-contextual-memory-in-adult-rats
#6
Ana Pocivavsek, Annalisa M Baratta, Jessica A Mong, Shaun S Viechweg
Study Objectives: Tryptophan metabolism via the kynurenine pathway may represent a key molecular link between sleep loss and cognitive dysfunction. Modest increases in the kynurenine pathway metabolite kynurenic acid (KYNA), which acts as an antagonist at N-methyl-d-aspartate and α7 nicotinic acetylcholine receptors in the brain, result in cognitive impairments. As glutamatergic and cholinergic neurotransmissions are critically involved in modulation of sleep, our current experiments tested the hypothesis that elevated KYNA adversely impacts sleep quality...
September 28, 2017: Sleep
https://www.readbyqxmd.com/read/29029291/nutrition-influences-caffeine-mediated-sleep-loss-in-drosophila
#7
Erin S Keebaugh, Jin Hong Park, Chenchen Su, Ryuichi Yamada, William W Ja
Study objectives: Plant-derived caffeine is regarded as a defensive compound produced to prevent herbivory. Caffeine is generally repellent to insects and often used to study the neurological basis for aversive responses in the model insect, Drosophila melanogaster. Caffeine is also studied for its stimulatory properties where sleep or drowsiness is suppressed across a range of species. Since limiting access to food also inhibits fly sleep-an effect known as starvation-induced sleep suppression-we tested whether aversion to caffeinated food results in reduced nutrient intake and assessed how this might influence fly studies on the stimulatory effects of caffeine...
October 3, 2017: Sleep
https://www.readbyqxmd.com/read/29024871/brain-energetics-during-the-sleep-wake-cycle
#8
REVIEW
Mauro DiNuzzo, Maiken Nedergaard
Brain activity during wakefulness is associated with high metabolic rates that are believed to support information processing and memory encoding. In spite of loss of consciousness, sleep still carries a substantial energy cost. Experimental evidence supports a cerebral metabolic shift taking place during sleep that suppresses aerobic glycolysis, a hallmark of environment-oriented waking behavior and synaptic plasticity. Recent studies reveal that glial astrocytes respond to the reduction of wake-promoting neuromodulators by regulating volume, composition and glymphatic drainage of interstitial fluid...
October 9, 2017: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/29024662/loss-of-clock-results-in-dysfunction-of-brain-circuits-underlying-focal-epilepsy
#9
Peijun Li, Xiaoqin Fu, Nathan A Smith, Julie Ziobro, Julian Curiel, Milagros J Tenga, Brandon Martin, Samuel Freedman, Christian A Cea-Del Rio, Livio Oboti, Tammy N Tsuchida, Chima Oluigbo, Amanda Yaun, Suresh N Magge, Brent O'Neill, Amy Kao, Tesfaye G Zelleke, Dewi T Depositario-Cabacar, Svetlana Ghimbovschi, Susan Knoblach, Chen-Ying Ho, Joshua G Corbin, Howard P Goodkin, Stefano Vicini, Molly M Huntsman, William D Gaillard, Gregorio Valdez, Judy S Liu
Because molecular mechanisms underlying refractory focal epilepsy are poorly defined, we performed transcriptome analysis on human epileptogenic tissue. Compared with controls, expression of Circadian Locomotor Output Cycles Kaput (CLOCK) is decreased in epileptogenic tissue. To define the function of CLOCK, we generated and tested the Emx-Cre; Clock(flox/flox) and PV-Cre; Clock(flox/flox) mouse lines with targeted deletions of the Clock gene in excitatory and parvalbumin (PV)-expressing inhibitory neurons, respectively...
October 11, 2017: Neuron
https://www.readbyqxmd.com/read/29024553/obesity-risk-factors-complications-and-strategies-for-sustainable-long-term-weight-management
#10
Sharon M Fruh
BACKGROUND AND PURPOSE: The aims of this article are to review the effects of obesity on health and well-being and the evidence indicating they can be ameliorated by weight loss, and consider weight-management strategies that may help patients achieve and maintain weight loss. METHODS: Narrative review based on literature searches of PubMed up to May 2016 with no date limits imposed. Search included terms such as "obesity," "overweight," "weight loss," "comorbidity," "diabetes," cardiovascular," "cancer," "depression," "management," and "intervention...
October 2017: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/29021568/the-brain-and-immune-system-prompt-energy-shortage-in-chronic-inflammation-and-ageing
#11
REVIEW
Rainer H Straub
Sequelae frequently seen in patients with chronic inflammatory diseases, such as fatigue, depressed mood, sleep alterations, loss of appetite, muscle wasting, cachectic obesity, bone loss and hypertension, can be the result of energy shortages caused by an overactive immune system. These sequelae can also be found in patients with chronic inflammatory diseases that are in remission and in ageing individuals, despite the immune system being less active in these situations. This Perspectives article proposes a new way of understanding situations of chronic inflammation (such as rheumatic diseases) and ageing based on the principles of evolutionary medicine, energy regulation and neuroendocrine-immune crosstalk...
October 12, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29019886/a-hospital-to-home-evaluation-of-an-enhanced-recovery-protocol-for-elective-pancreaticoduodenectomy-in-china-a-cohort-study
#12
Wei Su, Fangyan Lu, Xiaoyu Zhang, Guogang Li, Wei Chen, Tao Ma, Shunliang Gao, Jianying Lou, Xueli Bai, Tingbo Liang
Enhanced recovery after surgery (ERAS) programs have been shown to decrease postoperative complications and hospital stay in pancreaticoduodenectomy. However, no studies concerned recovery after discharge except readmission. This study evaluated an ERAS program for pancreaticoduodenectomy from hospital to home.A prospective ERAS cohort undergoing elective pancreaticoduodenectomy was compared with a retrospective control group in terms of postoperative complications and hospital stay, and home recovery after discharge...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29019051/the-link-between-narcolepsy-and-autonomic-cardiovascular-dysfunction-a-translational-perspective
#13
REVIEW
Chiara Berteotti, Alessandro Silvani
Narcolepsy is a rare disease that entails excessive daytime sleepiness, often associated with sudden episodes of muscle weakness known as cataplexy. Narcolepsy with cataplexy (NC) is due to the loss of hypothalamic neurons that release the neuropeptides orexin A and B. Orexin neuron projections prominently target brain structures involved in wake-sleep state switching and the central autonomic network. This review provides an updated summary of the links between NC and autonomic cardiovascular dysfunction from a translational perspective...
October 10, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/29017795/long-term-effects-of-sleep-deprivation-on-neuronal-activity-in-four-hypothalamic-areas
#14
Karim Fifel, Johanna H Meijer, Tom Deboer
Lack of adequate sleep has become increasingly common in our 24/7 society. Unfortunately diminished sleep has significant health consequences including metabolic and cardiovascular disease and mental disorders including depression. The pathways by which reduced sleep adversely affects physiology and behavior are unknown. We found that 6h of sleep deprivation in adult male rats induces changes in neuronal activity in the lateral hypothalamus, the paraventricular nucleus, the arcuate nucleus and the mammillary bodies...
October 7, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/29017480/longitudinal-assessment-of-daily-activity-patterns-on-weight-change-after-involuntary-job-loss-the-adapt-study-protocol
#15
Patricia L Haynes, Graciela E Silva, George W Howe, Cynthia A Thomson, Emily A Butler, Stuart F Quan, Duane Sherrill, Molly Scanlon, Darlynn M Rojo-Wissar, Devan N Gengler, David A Glickenstein
BACKGROUND: The World Health Organization has identified obesity as one of the most visible and neglected public health problems worldwide. Meta-analytic studies suggest that insufficient sleep increases the risk of developing obesity and related serious medical conditions. Unfortunately, the nationwide average sleep duration has steadily declined over the last two decades with 25% of U.S. adults reporting insufficient sleep. Stress is also an important indirect factor in obesity, and chronic stress and laboratory-induced stress negatively impact sleep...
October 10, 2017: BMC Public Health
https://www.readbyqxmd.com/read/29016235/telemedicine-support-groups-for-home-parenteral-nutrition-users
#16
Eve-Lynn Nelson, Donna Macan Yadrich, Noreen Thompson, Shawna Wright, Kathaleen Stone, Natasia Adams, Marilyn Werkowitch, Carol E Smith
Patients receiving home parenteral nutrition (HPN), a life-sustaining intravenous (IV) infusion that provides nourishment and hydration to patients with short gut or inflammatory bowel diseases, are often isolated and not in visual contact with peers or health providers. One completed clinical trial (Clinical Trials.gov NCT0190028) and 1 ongoing clinical trial (Clinical Trials.gov NCT02987569) are evaluating a mobile videoconferencing-delivered support group intervention for patients on HPN and their caregivers...
October 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28993495/sleep-research-goes-wild-new-methods-and-approaches-to-investigate-the-ecology-evolution-and-functions-of-sleep
#17
REVIEW
Niels C Rattenborg, Horacio O de la Iglesia, Bart Kempenaers, John A Lesku, Peter Meerlo, Madeleine F Scriba
Despite being a prominent aspect of animal life, sleep and its functions remain poorly understood. As with any biological process, the functions of sleep can only be fully understood when examined in the ecological context in which they evolved. Owing to technological constraints, until recently, sleep has primarily been examined in the artificial laboratory environment. However, new tools are enabling researchers to study sleep behaviour and neurophysiology in the wild. Here, we summarize the various methods that have enabled sleep researchers to go wild, their strengths and weaknesses, and the discoveries resulting from these first steps outside the laboratory...
November 19, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28988235/readmissions-and-emergency-department-visits-after-bariatric-surgery-at-saudi-arabian-hospital-the-rates-reasons-and-risk-factors
#18
Anwar Ahmed, Doaa AlBuraikan, Bashayr ALMuqbil, Wijdan AlJohi, Wala Alanazi, Budor AlRasheed
BACKGROUND: Saudi Arabian hospital readmissions and emergency department (ED) visits following bariatric surgery and discharge have never been investigated. This study aimed to evaluate the rates and reasons of hospital readmissions and ED visits related to surgical weight loss interventions at the King Abdulaziz Medical City - Riyadh. METHODS: We conducted a retrospective cohort study on 301 patients who underwent bariatric surgery between January 2011 and July 2016...
October 7, 2017: Obesity Facts
https://www.readbyqxmd.com/read/28986235/alpha-synuclein-epigenetics-mitochondria-metabolism-calcium-traffic-circadian-dysfunction-in-parkinson-s-disease-an-integrated-strategy-for-management
#19
REVIEW
Oliver T Phillipson
The motor deficits which characterise the sporadic form of Parkinson's disease arise from age-related loss of a subset of dopamine neurons in the substantia nigra. Although motor symptoms respond to dopamine replacement therapies, the underlying disease process remains. This review details some features of the progressive molecular pathology and proposes deployment of a combination of nutrients: R-lipoic acid, acetyl-l-carnitine, ubiquinol, melatonin (or receptor agonists) and vitamin D3, with the collective potential to slow progression of these features...
October 3, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28985629/dsm-5-alternative-model-of-personality-disorder-testing-the-trait-perspective-captured-in-criterion-b
#20
REVIEW
Joshua D Miller, Chelsea Sleep, Donald R Lynam
We review the trait model (i.e., Criterion B) included as a central piece of the alternative model of personality disorder (PD) included in DSM-5. The pathological traits are organized into five domains with 25 facets that overlap substantially with basic personality models (e.g., five-factor model). These PD traits can be reliably assessed using a variety of measures; however, questions of poor discriminant validity have been raised. Concerns were raised that this model would result in the loss of clinically meaningful constructs (e...
September 23, 2017: Current Opinion in Psychology
keyword
keyword
38849
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"