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https://www.readbyqxmd.com/read/28731929/impact-of-aortic-rather-than-brachial-pulsatile-haemodynamics-on-variations-in-end-organ-measures-across-the-full-adult-blood-pressure-range
#1
Bryan Hodson, Gavin R Norton, Imraan Ballim, Carlos D Libhaber, Pinhas Sareli, Angela J Woodiwiss
AIMS: To determine the extent to which the adverse effects of blood pressure (BP) are mediated by pulsatile haemodynamic changes across the normotensive as compared with the hypertensive adult brachial BP range, and whether aortic rather than brachial pulsatile changes best index these effects. METHODS: In 1307 community participants, the contribution of pulsatile haemodynamics (applanation tonometry and SphygmoCor software) to variations in left ventricular mass index (LVMI) (echocardiography) (n = 920), carotid intima-media thickness (IMT) (n = 712) and estimated glomerular filtration rate (eGFR) (n = 1164) were assessed...
July 20, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28731768/self-organized-velocity-pulses-of-dense-colloidal-suspensions-in-microchannel-flow
#2
Philipp Kanehl, Holger Stark
We present a numerical study of dense colloidal suspensions in a pressure-driven microchannel flow in two dimensions. The colloids are modeled as elastic and frictional spheres suspended in a Newtonian fluid, which we simulate using the method of multiparticle collision dynamics. The model reproduces periodic velocity and density pulse trains, traveling upstream in the microchannel, which are found in experiments conducted by Isa et al. [Phys. Rev. Lett. 102, 058302 (2009)PRLTAO0031-900710.1103/PhysRevLett...
July 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28731326/oxygen-partial-pressure-during-pulsed-laser-deposition-deterministic-role-on-thermodynamic-stability-of-atomic-termination-sequence-at-srruo3-batio3-interface
#3
Yeong Jae Shin, Lingfei Wang, Yoonkoo Kim, Ho-Hyun Nahm, Daesu Lee, Jeong Rae Kim, Sang Mo Yang, Jong-Gul Yoon, Jin-Seok Chung, Miyoung Kim, Seo Hyoung Chang, Tae Won Noh
With recent trends on miniaturizing oxide-based devices, the need for atomic-scale control of surface/interface structures by pulsed laser deposition (PLD) has increased. In particular, realizing uniform atomic termination at the surface/interface is highly desirable. However, a lack of understanding on the surface formation mechanism in PLD has limited a deliberate control of surface/interface atomic stacking sequences. Here, taking the prototypical SrRuO3/BaTiO3/SrRuO3 (SRO/BTO/SRO) heterostructure as a model system, we investigated the formation of different interfacial termination sequences (BaO-RuO2 or TiO2-SrO) with oxygen partial pressure (PO2) during PLD...
July 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28729675/oxygen-induced-impairment-in-arterial-function-is-corrected-by-slow-breathing-in-patients-with-type-1-diabetes
#4
Luciano Bernardi, Daniel Gordin, Marco Bordino, Milla Rosengård-Bärlund, Anna Sandelin, Carol Forsblom, Per-Henrik Groop
Hyperoxia and slow breathing acutely improve autonomic function in type-1 diabetes. However, their effects on arterial function may reveal different mechanisms, perhaps potentially useful. To test the effects of oxygen and slow breathing we measured arterial function (augmentation index, pulse wave velocity), baroreflex sensitivity (BRS) and oxygen saturation (SAT), during spontaneous and slow breathing (6 breaths/min), in normoxia and hyperoxia (5 L/min oxygen) in 91 type-1 diabetic and 40 age-matched control participants...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28728486/relationship-between-neck-circumference-insulin-resistance-and-arterial-stiffness-in-overweight-and-obese-subjects
#5
Francesco Fantin, Gabriele Comellato, Andrea P Rossi, Elisa Grison, Elena Zoico, Gloria Mazzali, Mauro Zamboni
Background Only a few studies have investigated the relationship between neck circumference and cardiometabolic risk. The aim of this study was to assess the relationships between neck circumference, waist circumference, metabolic variables and arterial stiffness in a group of overweight and obese subjects evaluating a possible independent role of neck circumference in determining arterial stiffness. Methods and results We studied 95 subjects (53 women) with an age range of 20-77 years and body mass index range from 25...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28726796/three-year-change-in-endothelin-1-and-markers-of-vascular-remodelling-in-a-bi-ethnic-south-african-cohort-the-sabpa-study
#6
C S du Plooy, C M C Mels, H W Huisman, R Kruger
South Africans are at high risk for developing cardiovascular disease. Endothelin-1 is known for its vasoconstrictive properties and its ability to contribute to vascular structural changes. In this study we investigated the association of change in endothelin-1 levels and change in markers implicated in vascular remodelling after 3 years. Serum endothelin-1 levels and markers of vascular remodelling such as carotid intima-media thickness, carotid cross-sectional wall area (CSWA) and arterial compliance were measured...
July 20, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28726571/primary-blast-causes-delayed-effects-without-cell-death-in-shell-encased-brain-cell-aggregates
#7
Thomas Sawyer, Yushan Wang, David V Ritzel, Tyson Josey, Mercy Villanueva, Cory Vair, Yanfeng Song, Yimin Shei, Steven Parks, Peggy Nelson, Grant Hennes, Lori McLaws, Changyan Fan
Previous work used underwater explosive exposures to isolate the effects of shock-induced principle stress without shear on rat brain aggregate cultures. This current study has utilized simulated air blast to expose aggregates in suspension and enclosed within a spherical shell, enabling the examination of a much more complex biomechanical insult. Culture medium-filled spheres were exposed to single pulse overpressures of 15-30 psi (6-7 msec duration) and measurements within the sphere at defined sites showed complex and spatially dependent pressure changes...
July 20, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28724951/n-terminal-pro-brain-natriuretic-peptide-and-associated-factors-in-the-general-working-population-a-baseline-survey-of-the-uranosaki-cohort-study
#8
Atsushi Tanaka, Hisako Yoshida, Atsushi Kawaguchi, Jun-Ichi Oyama, Norihiko Kotooka, Shigeru Toyoda, Teruo Inoue, Masafumi Natsuaki, Koichi Node
Few data on clinical characteristics associated with N-terminal pro-brain natriuretic peptide (NT-proBNP) or the clinical value of measuring NT-proBNP in the working population are available. The aim of the present study was to investigate the levels of NT-proBNP and their association with clinical variables in the Japanese general working population by using baseline data from the Uranosaki cohort study. In the study, the plasma concentration of NT-proBNP and some biomarkers were measured in addition to the standard health checkups at the workplace...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724946/diastolic-augmentation-index-improves-radial-augmentation-index-in-assessing-arterial-stiffness
#9
Yang Yao, Liling Hao, Lisheng Xu, Yahui Zhang, Lin Qi, Yingxian Sun, Benqiang Yang, Frans N van de Vosse, Yudong Yao
Arterial stiffness is an important risk factor for cardiovascular events. Radial augmentation index (AI r ) can be more conveniently measured compared with carotid-femoral pulse wave velocity (cfPWV). However, the performance of AI r in assessing arterial stiffness is limited. This study proposes a novel index AI rd , a combination of AI r and diastolic augmentation index (AI d ) with a weight α, to achieve better performance over AI r in assessing arterial stiffness. 120 subjects (43 ± 21 years old) were enrolled...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724570/childhood-thyroid-function-body-composition-and-cardiovascular-function
#10
Mirjana Barjaktarovic, Tim Korevaar, Romy Gaillard, Yolanda B de Rijke, Theo J Visser, Vincent Wv Jaddoe, Robin P Peeters
OBJECTIVE: The cardiovascular system is a known target for thyroid hormone. Early-life cardiovascular alterations may lead to a higher risk of cardiovascular disease in adulthood. Little is known about the effects of thyroid hormone on cardiovascular function during childhood, including the role of body composition in this association. DESIGN: Population-based prospective cohort of children (N=4251, median age 6 years, 95% range 5.7-8.0 years). METHODS: Thyroid stimulating hormone (TSH) and free thyroxine (FT4) concentrations were measured to assess thyroid function...
July 19, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28723965/the-prevalence-and-metabolic-characteristics-of-polycystic-ovary-syndrome-in-the-qatari-population
#11
Soha R Dargham, Lina Ahmed, Eric S Kilpatrick, Stephen L Atkin
OBJECTIVE: The prevalence of polycystic ovary syndrome (PCOS) in the Qatari population is unknown and hence the estimated impact on the local population cannot be determined. The purpose of this study was to estimate the prevalence and metabolic features of PCOS among Qatari women. DESIGN: Cross sectional analysis. PATIENTS: 3,017 Qatari subjects volunteered to be phenotyped and genotyped for the Qatar Biobank from which all women between the ages of 18-40 years were identified (750)...
2017: PloS One
https://www.readbyqxmd.com/read/28722695/cardiac-cycle-efficiency-and-dicrotic-pressure-variations-new-parameters-for-fluid-therapy-a-pilot-observational-study
#12
Antonio Messina, Salvatore M Romano, Eleonora Bonicolini, Davide Colombo, Gianmaria Cammarota, Marco Chiostri, Francesco Della Corte, Paolo Navalesi, Didier Payen, Stefano Romagnoli
BACKGROUND: During a fluid challenge, the changes in cardiac performance and peripheral circulatory tone are closely related to the position of the ventricle on the Frank-Starling curve. Some patients have a good haemodynamic response to a fluid challenge, others hardly any response. The early haemodynamic effects of a fluid challenge could predict the final response before the entire fluid volume has been administered. OBJECTIVE: To assess whether a multivariate logistic regression model, including pulse pressure variation (PPV), cardiac cycle efficiency (CCE), arterial elastance and the difference between the dicrotic pressure and both systolic and mean arterial pressure (SAP - Pdic and MAP - Pdic) can predict cardiac responsiveness early during a fluid challenge in comparison with the standard procedure described elsewhere...
June 19, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28722185/valsalva-maneuver-exacerbates-left-atrial-compression-in-patients-with-large-hiatal-hernia
#13
Christopher Naoum, Leonard Kritharides, Sonali R Gnanenthiran, David Martin, Gregory L Falk, John Yiannikas
INTRODUCTION: Hiatal hernia (HH) can cause left atrial (LA) compression and impair LA filling. We evaluated the cardiac effects of preload reduction and abdominal strain induced by Valsalva maneuver (VM) in large HH patients. METHODS: LA and left ventricular (LV) dimensions were measured using 2D transthoracic echocardiography at rest and during VM in HH patients (n=55, 70±10 years) and controls (n=22, 67±6 years). Biplane LV volumes (n=39) and mitral inflow pulse-wave Doppler parameters (n=27) were also evaluated...
July 18, 2017: Echocardiography
https://www.readbyqxmd.com/read/28721143/the-effect-of-antihypertensive-treatment-on-arterial-stiffness-and-serum-concentration-of-selected-matrix-metalloproteinases
#14
Marek Rajzer, Wiktoria Wojciechowska, Tomasz Kameczura, Agnieszka Olszanecka, Danuta Fedak, Michał Terlecki, Kalina Kawecka-Jaszcz, Danuta Czarnecka
INTRODUCTION: The aim of the study was to assess the arterial stiffness and serum levels of selected metalloproteinases (MMPs) in hypertensive patients and their changes following antihypertensive therapy. MATERIAL AND METHODS: The study group consisted of 95 patients with essential arterial hypertension (HT) stage 1 or 2 (mean age: 53.1 ±13.0 years). The control group consisted of 31 normotensives of the same age range. Hypertension patients were randomized to one of the following monotherapies for 6 months: quinapril, losartan, amlodipine, hydrochlorothiazide or bisoprolol...
June 2017: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/28719470/diurnal-variation-and-repeatability-of-arterial-stiffness-and-cardiac-output-measurements-in-the-third-trimester-of-uncomplicated-pregnancy
#15
Mohamed W Osman, Francesca Leone, Mintu Nath, Asma Khalil, David R Webb, Thompson G Robinson, Hatem A Mousa
AIM: To investigate same day repeated measures and diurnal variation of arterial stiffness, cardiac output (CO), stroke volume (SV) and total peripheral resistance (TPR) during the third trimester of normal pregnancy. METHODOLOGY: Pulse wave velocity (PWV) and augmentation index (AIx) were recorded using the Arteriograph, while CO, SV and TPR were recorded using noninvasive cardiac output monitoring. The measurements were obtained in the third trimester of pregnancy from 21 healthy pregnant women at four time points (morning, afternoon, evening and midnight) over a 24-h period...
July 14, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28718257/risk-factors-for-heat-related-deaths-during-the-june-2015-heat-wave-in-karachi-pakistan
#16
Syed Ghazanfar Saleem, Tehreem Ansari, Ashraf Shamshad Ali, Sara Fatima, Mariam Hassan Rizvi, Muhammad Abdul Samad
BACKGROUND: Mortality as a consequence of heat related illness is a public health concern. Emergency department (ED) experiences increased patients' flow and decreased survival as a consequence of heat stroke during the episodes of heat wave. The present study was conducted to identify the risk factors for mortality among victims of heat wave (17th - 23rd June), 2015 evaluated in the Emergency Department of The Indus Hospital (TIH), Karachi. METHODS: In this cross-sectional study data was retrospectively collected...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28717584/pulse-wave-analysis-with-diffusing-wave-spectroscopy
#17
Markus Belau, Wolfgang Scheffer, Georg Maret
Hypertension is a major risk factor for cardiovascular disease and thus at the origin of many deaths by e.g. heart attack or stroke. Hypertension is caused by many factors including an increase in arterial stiffness which leads to changes in pulse wave velocity and wave reflections. Those often result in an increased left ventricular load which may result in heart failure as well as an increased pulsatile pressure in the microcirculation l to damage to blood vessels. In order to specifically treat the different causes of hypertension it is desirable to perform a pulse wave analysis as a complement to measurements of systolic and diastolic pressure by brachial cuff sphygmomanometry...
July 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28716522/exercise-individualized-by-trimpi-method-reduces-arterial-stiffness-in-early-onset-type-2-diabetic-patients-a-randomized-controlled-trial-with-aerobic-interval-training
#18
Alfonso Bellia, Ferdinando Iellamo, Elisa De Carli, Aikaterini Andreadi, Elvira Padua, Mauro Lombardo, Giuseppe Annino, Francesca Campoli, Sara Tartaglione, Stefano D'Ottavio, David Della-Morte, Davide Lauro
BACKGROUND: Arterial stiffness (AS) and baroreflex sensitivity (BRS) are subclinical markers of vascular diseases in type 2 diabetes (T2D). We evaluated the effects of aerobic interval training (AIT), with loads prescribed according to individual heart rate and lactate profiling obtained during a baseline treadmill test (TRIMPi method), on AS and BRS in patients with early-onset T2D without cardiovascular complications. POPULATION STUDY AND METHODS: Twenty-two sedentary overweight T2D patients (aged 57±7years) were randomized to 12-weeks open-label of supervised AIT by TRIMPi (n=8) or unsupervised physical activity as per usual care (SOC) (n=11)...
June 17, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28714271/influence-of-residual-renal-function-in-carotid-modeling-as-a-marker-of-early-atherosclerosis-in-dialysis-patients
#19
Merita Rroji, Nereida Spahia, Saimir Seferi, Myftar Barbullushi, Goce Spasovski
Atherosclerosis is frequently present in patients with chronic kidney disease (CKD) treated with dialysis. We evaluated the association between residual renal function (RRF), phosphate level, inflammation and other risk factors in carotid modeling as a marker of early atherosclerosis in peritoneal dialysis (PD) compared with hemodialysis (HD) patients. We studied 39 stable PD and 53 HD patients on renal replacement therapy (RRT) for 3 to 36 months duration. B-mode ultrasonography was used to determine carotid artery intima media thickness (CIMT)...
July 17, 2017: Therapeutic Apheresis and Dialysis
https://www.readbyqxmd.com/read/28714239/self-powered-real-time-arterial-pulse-monitoring-using-ultrathin-epidermal-piezoelectric-sensors
#20
Dae Yong Park, Daniel J Joe, Dong Hyun Kim, Hyewon Park, Jae Hyun Han, Chang Kyu Jeong, Hyelim Park, Jung Gyu Park, Boyoung Joung, Keon Jae Lee
Continuous monitoring of an arterial pulse using a pressure sensor attached on the epidermis is an important technology for detecting the early onset of cardiovascular disease and assessing personal health status. Conventional pulse sensors have the capability of detecting human biosignals, but have significant drawbacks of power consumption issues that limit sustainable operation of wearable medical devices. Here, a self-powered piezoelectric pulse sensor is demonstrated to enable in vivo measurement of radial/carotid pulse signals in near-surface arteries...
July 17, 2017: Advanced Materials
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