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https://www.readbyqxmd.com/read/29786066/repeated-social-defeat-induced-neuroinflammation-anxiety-like-behavior-and-resistance-to-fear-extinction-were-attenuated-by-the-cannabinoid-receptor-agonist-win55-212-2
#1
Sabrina Francesca Lisboa, Anzela Niraula, Leonardo Barbosa Resstel, Francisco Silveira Guimaraes, Jonathan P Godbout, John F Sheridan
Psychosocial stress contributes to the development of psychiatric disorders. Repeated social defeat (RSD) is a murine stressor that causes a release of inflammatory monocytes into circulation. Moreover, RSD-induced anxiety-like behavior is dependent on the recruitment of these monocytes to the brain. Activation of the endocannabinoid (ECB) system may modulate both neuroendocrine and inflammatory responses mediated by stress. Therefore, we hypothesized that a cannabinoid receptor agonist would attenuate RSD-induced inflammation, anxiety, and stress sensitization...
April 17, 2018: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29782423/the-development-of-the-working-alliance-and-its-ability-to-predict-outcome-in-emotion-focused-therapy-for-social-anxiety-disorder
#2
Gilad Adler, Ben Shahar, Tohar Dolev, Sigal Zilcha-Mano
The study focuses on the alliance of 12 patients receiving emotion-focused therapy for social anxiety. Anxiety symptoms and patient perception of the working alliance were examined weekly. The first eight sessions of each patient were coded for within- and between-sessions alliance levels (1008 segments were coded). At the sample level, the alliance shows linear development over time but high variability between individuals. More than half the patients showed alliance development consistent with the rupture-resolution pattern...
May 17, 2018: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/29782305/tatami-mats-a-source-of-pitted-keratolysis-in-a-martial-arts-athlete
#3
Anamaria Balić, Zrinka Bukvić Mokos, Branka Marinović, Daniela Ledić Drvar
Dear Editor, Pitted keratolysis (PK), also known as keratosis plantaris sulcatum, is a non-inflammatory, bacterial, superficial cutaneous infection, characterized by many discrete superficial crateriform ''pits'' and erosions in the thickly keratinized skin of the weight-bearing regions of the soles of the feet (1). The disease often goes unnoticed by the patient, but when it is noticed it is because of the unbearable malodor and hyperhidrosis of the feet, which are socially unacceptable and cause great anxiety to many of the patients...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29781649/treatment-of-social-approach-processes-in-adults-with-social-anxiety-disorder
#4
Lynn E Alden, Kristin Buhr, Melisa Robichaud, Jennifer L Trew, M Leili Plasencia
OBJECTIVE: Despite the social impairment associated with social anxiety disorder (SAD), little research has examined the impact of treatment on positive relational functioning. Accordingly, the authors conducted a treatment outcome study to evaluate a cognitive behavior therapy (CBT) regimen augmented by a relational focus (CBT-R) relative to a graduated exposure-applied relaxation (GEAR) regimen and wait list (WL) control. To examine the mechanism(s) that underlies treatment effects, they used structural equation modeling (SEM) to evaluate two potential mediators, change in judgment biases and in safety behaviors...
June 2018: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/29781648/a-mobile-app-for-social-anxiety-disorder-a-three-arm-randomized-controlled-trial-comparing-mobile-and-pc-based-guided-self-help-interventions
#5
Timo Stolz, Ava Schulz, Tobias Krieger, Alessia Vincent, Antoine Urech, Christian Moser, Stefan Westermann, Thomas Berger
OBJECTIVE: Internet-based cognitive-behavioral treatments (ICBT) have shown promise for various mental disorders, including social anxiety disorder (SAD). Most of these treatments have been delivered on desktop computers. However, the use of smartphones is becoming ubiquitous and could extend the reach of ICBT into users' everyday life. Only a few studies have empirically examined the efficacy of ICBT delivered through a smartphone app and there is no published study on mobile app delivered ICBT for SAD...
June 2018: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/29781314/is-social-media-bad-for-mental-health-and-wellbeing-exploring-the-perspectives-of-adolescents
#6
Michelle O'Reilly, Nisha Dogra, Natasha Whiteman, Jason Hughes, Seyda Eruyar, Paul Reilly
Despite growing evidence of the effects of social media on the mental health of adolescents, there is still a dearth of empirical research into how adolescents themselves perceive social media, especially as knowledge resource, or how they draw upon the wider social and media discourses to express a viewpoint. Accordingly, this article contributes to this scarce literature. Six focus groups took place over 3 months with 54 adolescents aged 11-18 years, recruited from schools in Leicester and London (UK)...
May 1, 2018: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/29781234/the-unsafe-haven-eating-disorders-as-attachment-relationships
#7
Emma Forsén Mantilla, David Clinton, Andreas Birgegård
OBJECTIVES: Some patients with eating disorders (EDs) seem to experience their illness as an entity, a symbolic other to whom they relate, and which may influence both symptom levels and self-image. Extending previous research, this study investigated whether the patient-ED relationship has attachment qualities. DESIGN: Structural Analysis of Social Behaviour was used to operationalize the patient-ED relationship, and the Attachment Style Questionnaire was used to measure attachment...
May 21, 2018: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/29779855/transportability-of-imagery-enhanced-cbt-for-social-anxiety-disorder
#8
Peter M McEvoy, David M Erceg-Hurn, Kevin C Barber, Jessica R Dupasquier, David A Moscovitch
Pilot and open trials suggest that imagery-enhanced group cognitive behaviour therapy (CBT) is highly effective for social anxiety disorder (SAD). However, before being considered reliable and generalisable, the effects of the intervention need to be replicated by clinicians in a setting that is independent of the protocol developers. The current study compared outcomes from clients with a principal diagnosis of SAD at the Australian clinic where the protocol was developed (n = 123) to those from an independent Canadian clinic (n = 46) to investigate whether the large effects would generalise...
May 14, 2018: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29778712/validation-reliability-and-specificity-of-clinicom%C3%A2-psychiatric-assessment-software
#9
Nelson Handal, James LePage, Philip Dayley, Barbara Baldwin, Amellia Roeser, Joni Kay, Heather Ann Theobald, Michael Nellamattathil, Scott Drotar, Connor Weir, Neil Tindell, Kevin Tice
The purpose of this study was to determine the specificity and reproducibility of CliniCom™ Psychiatric Assessment Software to appropriately diagnose five prevalent mental health disorders. This online assessment tool incorporates proprietary algorithms for its propensity assessment. Unlike other questionnaires, which require a survey per specific mental disorder, CliniCom can simultaneously assess multiple mental disorders for an individual. CliniCom was concordant with other commonly used assessment tools in diagnosing five prevalent disorders including: Attention Deficit and Hyperactivity Disorder, Generalized Anxiety Disorder, Major Depressive Disorder, Obsessive Compulsive Disorder, and Social Phobia...
May 12, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29777479/frontal-delta-beta-cross-frequency-coupling-in-high-and-low-social-anxiety-an-index-of-stress-regulation
#10
Eefje S Poppelaars, Anita Harrewijn, P Michiel Westenberg, Melle J W van der Molen
Cross-frequency coupling (CFC) between frontal delta (1-4 Hz) and beta (14-30 Hz) oscillations has been suggested as a candidate neural correlate of social anxiety disorder, a disorder characterized by fear and avoidance of social and performance situations. Prior studies have used amplitude-amplitude correlation (AAC) as a CFC measure and hypothesized it as a candidate neural mechanism of affective control. However, using this metric has yielded inconsistent results regarding the direction of CFC, and the functional significance of coupling strength is uncertain...
May 17, 2018: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/29777110/using-network-analysis-for-the-prediction-of-treatment-dropout-in-patients-with-mood-and-anxiety-disorders-a-methodological-proof-of-concept-study
#11
Wolfgang Lutz, Brian Schwartz, Stefan G Hofmann, Aaron J Fisher, Kristin Husen, Julian A Rubel
There are large health, societal, and economic costs associated with attrition from psychological services. The recently emerged, innovative statistical tool of complex network analysis was used in the present proof-of-concept study to improve the prediction of attrition. Fifty-eight patients undergoing psychological treatment for mood or anxiety disorders were assessed using Ecological Momentary Assessments four times a day for two weeks before treatment (3,248 measurements). Multilevel vector autoregressive models were employed to compute dynamic symptom networks...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29776708/predictors-of-treatment-outcome-for-the-unified-protocol-for-transdiagnostic-treatment-of-emotional-disorders-in-children-up-c
#12
Sarah M Kennedy, Niza A Tonarely, Jamie A Sherman, Jill Ehrenreich-May
Various efficacious treatment packages exist for youth anxiety, and cognitive behavior therapy (CBT) is now considered to be a well-established treatment for child anxiety disorders (Higa-McMillan, Francis, Rith-Najarian, & Chorpita, 2016). Improving outcomes for the significant proportion of anxious youth who demonstrate inadequate response to CBT is imperative, but our understanding of who does and does not benefit is incomplete. Further, there are no known empirical studies of predictors of treatment response for youth who receive a transdiagnostic intervention for anxiety or depression, and it is therefore unclear whether predictors of response to a transdiagnostic treatment for children are similar to those found in previous studies of anxiety-specific treatments...
May 15, 2018: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29774787/variability-of-attention-bias-in-socially-anxious-adolescents-differences-in-fixation-duration-toward-adult-and-adolescent-face-stimuli
#13
Andrea Trubanova Wieckowski, Nicole N Capriola-Hall, Rebecca Elias, Thomas H Ollendick, Susan W White
Prior research on attention bias in anxious youth, often utilising a visual dot probe task, has yielded inconsistent findings, which may be due to how bias is assessed and/or variability in the phenomenon. The present study utilises eye gaze tracking to assess attention bias in socially anxious adolescents, and explores several methodological and within-subject factors that may contribute to variability in attention bias. Attention bias to threat was measured in forty-two treatment-seeking adolescents (age 12-16 years) diagnosed with Social Anxiety Disorder...
May 18, 2018: Cognition & Emotion
https://www.readbyqxmd.com/read/29773244/are-anxiety-disorders-publications-continuing-on-a-trajectory-of-growth-a-look-at-boschen-s-2008-predictions-and-beyond
#14
Gordon J G Asmundson, Aleiia J N Asmundson
The relative health of a field of research can be approximated by assessing peer-reviewed journal publication trends for articles pertinent to that field. The most recent comprehensive assessment of publication trends in the anxiety disorders indicated that the field was on a continuing trajectory of growth (Boschen, 2008). We conducted an updated search of Medline for publications on each of the anxiety disorders from 2006 to 2016. Results indicated that there was continuing growth in anxiety disorders research overall and, particularly, for posttraumatic stress disorder, social anxiety disorder, generalized anxiety disorder, and obsessive compulsive disorder...
May 14, 2018: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/29772912/relations-between-empathy-and-anxiety-dimensions-in-inpatient-adolescents
#15
Malgorzata Gambin, Carla Sharp
BACKGROUND AND OBJECTIVES: A better understanding of the relationships between empathy and internalizing disorders is needed to plan therapeutic interventions for children and adolescents. Several studies have revealed positive relations of internalizing symptoms to personal distress and affective empathy. However, there is a lack of studies that take into account the multidimensional nature of anxiety in its relation to empathy. DESIGN: Structural equation modeling was used to test the moderated mediation model of the relations between empathy, depression and anxiety dimensions and the moderating role of gender on these associations in inpatient adolescents...
May 17, 2018: Anxiety, Stress, and Coping
https://www.readbyqxmd.com/read/29772772/multiplicative-effects-of-social-and-psychological-risk-factors-on-college-students-suicidal-behaviors
#16
Shervin Assari
Less is known about the multiplicative effects of social and psychological risk and protective factors of suicidality on college campuses. The current study aimed to investigate the multiplicative effects of social (identifying oneself as gay/lesbian, financial difficulty, violence victimization, and religiosity) and psychological (anxiety, depression, problem alcohol use, drug use) and risk/protective factors on suicidal behaviors among college students in the United States. Using a cross-sectional design, the Healthy Mind Study (HMS; 2016⁻2017), is a national online survey of college students in the United States...
May 17, 2018: Brain Sciences
https://www.readbyqxmd.com/read/29772261/maternal-immune-activation-with-staphylococcal-enterotoxin-a-produces-unique-behavioral-changes-in-c57bl-6-mouse-offspring
#17
Ruthy Glass, Sara Norton, Nicholas Fox, Alexander W Kusnecov
Stimulation of the immune system during pregnancy, known as maternal immune activation (MIA), can cause long-lasting neurobiological and behavioral changes in the offspring. This phenomenon has been implicated in the etiology of developmental psychiatric disorders, such as autism and schizophrenia. Much of this evidence is predicated on animal models using bacterial agents such as LPS and/or viral mimics such as Poly I:C, both of which act through toll-like receptors. However, fewer studies have examined the role of direct activation of maternal T-cells during pregnancy using microbial agents...
May 14, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29769115/lifestyle-choices-and-mental-health-a-longitudinal-survey-with-german-and-chinese-students
#18
Julia Velten, Angela Bieda, Saskia Scholten, André Wannemüller, Jürgen Margraf
BACKGROUND: A healthy lifestyle can be beneficial for one's mental health. Thus, identifying healthy lifestyle choices that promote psychological well-being and reduce mental problems is useful to prevent mental disorders. The aim of this longitudinal study was to evaluate the predictive values of a broad range of lifestyle choices for positive mental health (PMH) and mental health problems (MHP) in German and Chinese students. METHOD: Data were assessed at baseline and at 1-year follow-up...
May 16, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29766462/disgust-and-fear-common-emotions-between-eating-and-phobic-disorders
#19
Rami Bou Khalil, Ibrahim R Bou-Orm, Yara Tabet, Lama Souaiby, Hayat Azouri
Eating disorders (ED) are prevalent mental illnesses composed mainly of anorexia nervosa, bulimia nervosa and binge eating disorders. Anxiety disorders are another set of mental illnesses, with phobic disorder (PD) being the most prevalent disorder. ED and PD are highly comorbid. The aim of this study is to assess, in 131 individuals attending an outpatient clinic for different health issues, the level of fear related to situations generating avoidance such as in social anxiety and specific phobias according to the fear questionnaire (FQ), the level of disgust according to the disgust scale (DS-R) and the vulnerability towards ED according to the SCOFF scale to demonstrate that high levels of both fear and disgust increase the vulnerability towards ED...
May 15, 2018: Eating and Weight Disorders: EWD
https://www.readbyqxmd.com/read/29764602/psychiatric-disorders-among-people-living-with-hiv-aids-in-iran-prevalence-severity-service-utilization-and-unmet-mental-health-needs
#20
Behrang Shadloo, Masoumeh Amin-Esmaeili, Abbas Motevalian, Minoo Mohraz, Abbas Sedaghat, Mohammad Mehdi Gouya, Afarin Rahimi-Movaghar
BACKGROUND: HIV and psychiatric disorders are closely correlated and are accompanied by some similar risk factors. OBJECTIVE: The aim of this study was to assess psychiatric comorbidity and health service utilization for mental problems among people living with HIV/AIDS in Iran. METHODS: A total of 250 cases were randomly selected from a large referral center for HIV treatment and care in Tehran, Iran. Psychiatric disorders in the past 12 months including mood, anxiety, and substance use disorders were assessed through face-to-face interview, using a validated Persian translation of the Composite International Diagnostic Interview (CIDI v2...
July 2018: Journal of Psychosomatic Research
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