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https://www.readbyqxmd.com/read/28632771/avian-influenza-in-latin-america-a-systematic-review-of-serological-and-molecular-studies-from-2000-2015
#1
Alejandra Afanador-Villamizar, Carlos Gomez-Romero, Andres Diaz, Julian Ruiz-Saenz
Avian influenza or bird flu is a highly contagious acute viral disease that can occur in epidemics and cross-border forms in poultry and wild birds. The characteristics of avian influenza viruses (AIVs) allow the emergence of new viral variants, some with zoonotic and pandemic potential. AIVs have been identified in Latin America; however, there is a lack of understanding of these viruses at the regional level. We performed a systematic literature review on serological or molecular evidence of AIVs circulation in Latin America...
2017: PloS One
https://www.readbyqxmd.com/read/28631116/environmental-factors-and-zoonotic-pathogen-ecology-in-urban-exploiter-species
#2
REVIEW
Jamie L Rothenburger, Chelsea H Himsworth, Nicole M Nemeth, David L Pearl, Claire M Jardine
Knowledge of pathogen ecology, including the impacts of environmental factors on pathogen and host dynamics, is essential for determining the risk that zoonotic pathogens pose to people. This review synthesizes the scientific literature on environmental factors that influence the ecology and epidemiology of zoonotic microparasites (bacteria, viruses and protozoa) in globally invasive urban exploiter wildlife species (i.e., rock doves [Columba livia domestica], European starlings [Sturnus vulgaris], house sparrows [Passer domesticus], Norway rats [Rattus norvegicus], black rats [R...
June 19, 2017: EcoHealth
https://www.readbyqxmd.com/read/28631053/characterization-of-an-orf-virus-isolate-from-an-outbreak-in-heilongjiang-province-china
#3
Yongzhong Yu, Qiang Tan, Wenbo Zhao, Xue Zhang, Jinzhu Ma, Zhijun Wu, Zhanbo Zhu, Yudong Cui
Contagious ecthyma, caused by orf virus (ORFV), is an epitheliotrophic contagious disease with zoonotic implications that mainly affects sheep, goats, wild ruminants, and humans. Recently, a novel ORFV strain, OV/HLJ/04, was successfully isolated from the skin and mucosal lesions of a goat with severe clinical sore mouth symptoms in Heilongjiang province of China. The OV/HLJ/04 isolate was characterized by electron microscopy, serological tests, and experimental reproduction of disease. The purified virions exhibited a typical ovoid shape when observed by electron microscopy...
June 19, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28630747/global-patterns-in-coronavirus-diversity
#4
Simon J Anthony, Christine K Johnson, Denise J Greig, Sarah Kramer, Xiaoyu Che, Heather Wells, Allison L Hicks, Damien O Joly, Nathan D Wolfe, Peter Daszak, William Karesh, W I Lipkin, Stephen S Morse, Jonna A K Mazet, Tracey Goldstein
Since the emergence of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrom Coronavirus (MERS-CoV) it has become increasingly clear that bats are important reservoirs of CoVs. Despite this, only 6% of all CoV sequences in GenBank are from bats. The remaining 94% largely consist of known pathogens of public health or agricultural significance, indicating that current research effort is heavily biased towards describing known diseases rather than the 'pre-emergent' diversity in bats...
January 2017: Virus Evolution
https://www.readbyqxmd.com/read/28630383/balb-c-mice-immunity-to-hydatidosis-induced-by-in-vitro-reared-echinococcus-granulosus-adult-worm-antigens
#5
Hamid Reza Rahimi, Tahereh Mohammadzadeh, Seyed Mahmoud Sadjjadi, Bahador Sarkari, Farzaneh Zahabiun
BACKGROUND: Echinococcosis is a zoonotic parasitic disease caused by the larval stage of Echinococcus granulosus. Several native and recombinant antigens, derived from different stages of E. granulosus life cycle, have been used for vaccine trials. In vitro reared adult worms are good candidates for vaccination as they do not produce fertile egg/s and do not have any risk of contamination for researchers. OBJECTIVE: To evaluate different antigens derived from in vitro reared E...
June 2017: Iranian Journal of Immunology: IJI
https://www.readbyqxmd.com/read/28629988/4-azidocytidine-r1479-inhibits-henipaviruses-and-other-paramyxoviruses-with-high-potency
#6
Anne L Hotard, Biao He, Stuart T Nichol, Christina F Spiropoulou, Michael K Lo
The henipaviruses Nipah virus and Hendra virus are highly pathogenic zoonotic paramyxoviruses which have caused fatal outbreaks of encephalitis and respiratory disease in humans. Despite the availability of a licensed equine Hendra virus vaccine and a neutralizing monoclonal antibody shown to be efficacious against henipavirus infections in non-human primates, there remains no approved therapeutics or vaccines for human use. To explore the possibility of developing small-molecule nucleoside inhibitors against henipaviruses, we evaluated the antiviral activity of 4'-azidocytidine (R1479), a drug previously identified to inhibit flaviviruses, against henipaviruses along with other representative members of the family Paramyxoviridae...
June 16, 2017: Antiviral Research
https://www.readbyqxmd.com/read/28629726/th2-related-immune-responses-by-the-brucella-abortus-cellular-antigens-malate-dehydrogenase-elongation-factor-and-arginase
#7
Young Bin Im, Soojin Shim, Woo Bin Park, Suk Kim, Han Sang Yoo
Brucellosis is an important zoonotic disease caused by Brucella species. The disease is difficult to control due to the intracellular survival of the bacterium and the lack of precise understanding of pathogenesis. Despite of continuous researches on the pathogenesis of Brucella spp. infection, there is still question on the pathogenesis, especially earlier immune response in the bacterial infection. Malate dehydrogenase (MDH), elongation factor (Tsf), and arginase (RocF), which showed serological reactivity, were purified after gene cloning, and their immune modulating activities were then analyzed in a murine model...
June 16, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28627433/comparison-of-g-protein-sequences-of-south-african-street-rabies-viruses-showing-distinct-progression-of-the-disease-in-a-mouse-model-of-experimental-rabies
#8
Wonhyo Seo, Alexandre Servat, Florence Cliquet, Jenkins Akinbowale, Christophe Prehaud, Monique Lafon, Claude Sabeta
Rabies is a fatal zoonotic disease and infections generally lead to a fatal encephalomyelitis in both humans and animals. In South Africa, domestic (dogs) and the wildlife (yellow mongoose) host species maintain the canid and mongoose rabies variants respectively. In this study, pathogenicity differences of South African canid and mongoose rabies viruses were investigated in a murine model, by assessing the progression of clinical signs and survivorship. Comparison of glycoprotein gene sequences revealed amino acid differences that may underpin the observed pathogenicity differences...
June 13, 2017: Microbes and Infection
https://www.readbyqxmd.com/read/28625886/zoonotic-and-vector-borne-diseases-in-urban-slums-opportunities-for-intervention
#9
Federico Costa, Ticiana Carvalho-Pereira, Mike Begon, Lee Riley, James Childs
Urban slums provide conditions that increase the risk of exposure to vector-borne and zoonotic pathogens. Large interventions, such as social and sanitary changes, are a priority but their implementation is challenging. Integration between the multidisciplinary understanding of pathogens' dynamics and community participatory approaches is a key prevention strategy.
June 15, 2017: Trends in Parasitology
https://www.readbyqxmd.com/read/28624926/limited-awareness-of-animal-influenza-prevention-and-control-among-dai-lue-smallholder-farmers-in-southwest-china
#10
Xiang Zhao, Gareth Davey
Awareness of animal influenza and its prevention and control is important for ensuring livestock health, production and welfare. In China, a country stereotyped as a major source of emerging zoonotic infectious diseases, research on the public understanding of animal influenza is limited to the Han, the main ethnic group. The present qualitative study in Southwest China investigated awareness of animal influenza among the Dai, an ethnic minority. The participants (15 men and 10 women, ages 18-83) were smallholder farmers of pigs and poultry in rural areas of Jinghong, Xishuangbanna, Yunnan Province...
June 17, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28624512/epidemiological-investigation-and-risk-factors-of-echinococcus-granulosus-in-yaks-bos-grunniens-tibetan-pigs-and-tibetans-on-qinghai-tibetan-plateau
#11
Kun Li, Lihong Zhang, Hui Zhang, Zhixin Lei, Houqiang Luo, Khalid Mehmood, Muhammad Shahzad, Yanfang Lan, Meng Wang, Jiakui Li
Echinococcus granulosus (E. granulosus) is a diverse zoonotic parasite and causes Cystic echinococcosis (CE) disease in humans and livestock. However, scare information is available about the epidemic situation of E. granulosus infection in yaks, Tibetan pigs and native Tibetans on the Qinghai Tibetan plateau. Therefore, a study was carried out to find prevalence and risk factors of E. granulosus in yaks, Tibetan pigs and Tibetans. Serum samples from yaks (1371), Tibetan pigs (454) and Tibetans (600) were collected and assessed by commercial ELISA kits...
June 15, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28623676/unrecognized-pediatric-and-adult-family-members-of-children-with-acute-brucellosis
#12
Dilek Yılmaz Çiftdoğan, Selda Aslan
BACKGROUND AND AIM: Brucellosis is an infectious, contagious and zoonotic disease that occurs worldwide. The family members of an index case of brucellosis may be especially susceptible, due to sharing the same source of infection and similar risk factors for brucellosis. In this study, we propose to screen pediatric and adult family members of brucellosis index cases for detecting additional unrecognized infected family members. MATERIALS AND METHODS: 114 family members of 41 pediatric patients with brucellosis were evaluated...
June 14, 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28622857/streptococcus-suis-serotype-9-strain-gz0565-contains-a-type-vii-secretion-system-putative-substrate-esxa-that-contributes-to-bacterial-virulence-and-a-vanz-like-gene-that-confers-resistance-to-teicoplanin-and-dalbavancin-in-streptococcus-agalactiae
#13
Liying Lai, Jiao Dai, Huanyu Tang, Shouming Zhang, Chunyan Wu, Wancen Qiu, Chengping Lu, Huochun Yao, Hongjie Fan, Zongfu Wu
Streptococcus suis (SS), an important pathogen for pigs, is not only considered as a zoonotic agent for humans, but is also recognized as a major reservoir of antimicrobial resistance contributing to the spread of resistance genes to other pathogenic Streptococcus species. In addition to serotype 2 (SS2), serotype 9 (SS9) is another prevalent serotype isolated from diseased pigs. Although many SS strains have been sequenced, the complete genome of a non-SS2 virulent strain has been unavailable to date. Here, we report the complete genome of GZ0565, a virulent strain of SS9, isolated from a pig with meningitis...
June 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28622789/characterization-of-the-epidemiology-of-bat-borne-rabies-in-chile-between-2003-and-2013
#14
Raul Alegria-Moran, Daniela Miranda, Matt Barnard, Alonso Parra, Lisette Lapierre
Rabies is a zoonotic disease of great impact to public health. According to the World Health Organization, the country of Chile is currently declared free from human rabies transmitted by dogs. An epidemiological characterization and description was conducted using rabies data from 2003 to 2013 held by the National Program for Prevention and Control of Rabies from the Ministry of Health, consisting of bats samples reported as suspect and samples taken by active surveillance (bats brain tissue). Spatial autocorrelation analysis was performed using Local Indicators of Spatial Association (LISA) statistics, particularly Moran's I index, for the detection of spatial clusters...
August 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28621333/francisella-requires-dynamic-type-vi-secretion-system-and-clpb-to-deliver-effectors-for-phagosomal-escape
#15
Maj Brodmann, Roland F Dreier, Petr Broz, Marek Basler
Francisella tularensis is an intracellular pathogen that causes the fatal zoonotic disease tularaemia. Critical for its pathogenesis is the ability of the phagocytosed bacteria to escape into the cell cytosol. For this, the bacteria use a non-canonical type VI secretion system (T6SS) encoded on the Francisella pathogenicity island (FPI). Here we show that in F. novicida T6SS assembly initiates at the bacterial poles both in vitro and within infected macrophages. T6SS dynamics and function depends on the general purpose ClpB unfoldase, which specifically colocalizes with contracted sheaths and is required for their disassembly...
June 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/28619055/molecular-typing-of-leptospira-interrogans-serovar-hardjo-isolates-from-leptospirosis-outbreaks-in-brazilian-livestock
#16
Maria Raquel V Cosate, Tetsu Sakamoto, Tiago Antônio de Oliveira Mendes, Élvio C Moreira, Carlos G Regis da Silva, Bruno S A F Brasil, Camila S F Oliveira, Vasco Ariston de Azevedo, José Miguel Ortega, Rômulo C Leite, João Paulo Haddad
BACKGROUND: Leptospirosis is caused by pathogenic spirochetes of the genus Leptospira spp. This zoonotic disease is distributed globally and affects domestic animals, including cattle. Leptospira interrogans serogroup Sejroe serovar Hardjo and Leptospira borgpetersenii serogroup Sejroe serovar Hardjo remain important species associated with this reproductive disease in livestock production. Previous studies on Brazilian livestock have reported that L. interrogans serovar Hardjo is the most prevalent leptospiral agent in this country and is related to clinical signs of leptospirosis, which lead to economic losses in production...
June 15, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28617836/molecular-diversity-and-frequency-of-the-diarrheagenic-enteric-protozoan-giardia-duodenalis-and-cryptosporidium-spp-in-a-hospital-setting-in-northern-spain
#17
José Manuel Azcona-Gutiérrez, Aida de Lucio, Marta Hernández-de-Mingo, Concepción García-García, Luis Miguel Soria-Blanco, Lucía Morales, María Aguilera, Isabel Fuentes, David Carmena
BACKGROUND: Human giardiosis and cryptosporidiosis are caused by the enteric protozoan parasites Giardia duodenalis and Cryptosporidium spp. Both pathogens are major contributors to the global burden of diarrhoeal disease, affecting primarily children and immunodebilitated individuals in resource-poor settings. Giardiosis and cryptosporidiosis also represent an important, often underestimate, public health threat in developed countries. In Spain only limited information is currently available on the epidemiology of these infections...
2017: PloS One
https://www.readbyqxmd.com/read/28616494/community-based-surveillance-of-zoonotic-parasites-in-a-one-health-world-a-systematic-review
#18
REVIEW
J M Schurer, E Mosites, C Li, S Meschke, P Rabinowitz
The One Health (OH) concept provides an integrated framework for observing and improving health issues involving human, animal, and environmental factors, and has been applied in particular to zoonotic disease problems. We conducted a systematic review of English and Chinese language peer-reviewed and grey literature databases to identify zoonotic endoparasite research utilizing an OH approach in community-based settings. Our review identified 32 articles where specimens collected simultaneously from all three OH domains (people, animals, and the environment) were assessed for endoparasite infection or exposure...
December 2016: One Health
https://www.readbyqxmd.com/read/28616486/goat-farm-management-and-brucella-serological-test-among-goat-keepers-and-livestock-officers-2011-2012-nakhon-si-thammarat-province-southern-thailand
#19
Thanidtha Te-Chaniyom, Alan F Geater, Wandee Kongkaew, Usa Chethanond, Virasakdi Chongsuvivatwong
Brucellosis, a zoonotic disease particularly affecting goats, emerged in Thailand in 2003, resulting in both an occupational hazard for goat keepers and livestock officers, and production losses. Farm management practices have been identified as risk factors associated with Brucella sero-positivity in many studies. Our finding in this study should be considered in order to strengthen the system of biosecurity control in farm animals as one health approach. The objectives of the study were to describe the distribution of potential risk factors by types of goat farms and to document the prevalence of human Brucella sero-positivity among goat keepers and livestock officers in Nakhon Si Thammarat, Thailand...
December 2016: One Health
https://www.readbyqxmd.com/read/28616478/human-livestock-contacts-and-their-relationship-to-transmission-of-zoonotic-pathogens-a-systematic-review-of-literature
#20
REVIEW
Gijs Klous, Anke Huss, Dick J J Heederik, Roel A Coutinho
BACKGROUND: Micro-organisms transmitted from vertebrate animals - including livestock - to humans account for an estimated 60% of human pathogens. Micro-organisms can be transmitted through inhalation, ingestion, via conjunctiva or physical contact. Close contact with animals is crucial for transmission. The role of intensity and type of contact patterns between livestock and humans for disease transmission is poorly understood. In this systematic review we aimed to summarise current knowledge regarding patterns of human-livestock contacts and their role in micro-organism transmission...
December 2016: One Health
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