Masakazu Saeki, Seiichi Munesue, Yuri Higashi, Ai Harashima, Ryohei Takei, Satoshi Takada, Shinichi Nakanuma, Tetsuo Ohta, Shintaro Yagi, Hidehiro Tajima, Yasuhiko Yamamoto
Sinusoidal obstruction syndrome (SOS) is a serious liver disorder that occurs after liver transplantation, hematopoietic stem cell transplantation, and the administration of anticancer drugs. Since SOS is a life-threatening condition that can progress to liver failure, early detection and prompt treatment are required for the survival of patients with this condition. In this study, female CD1 mice were divided into treatment and control groups after the induction of an SOS model using monocrotaline (MCT, 270 mg/kg body weight intraperitoneally)...
November 15, 2023: International Journal of Molecular Sciences