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https://www.readbyqxmd.com/read/28495654/minimally-invasive-surgical-ablation-should-we-ablate-harder-or-smarter
#1
EDITORIAL
David Callans, Ramanan Kumareswaran
No abstract text is available yet for this article.
May 8, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28490605/adhesion-modulation-using-glue-droplet-spreading-in-spider-capture-silk
#2
Gaurav Amarpuri, Ci Zhang, Todd A Blackledge, Ali Dhinojwala
Orb web spiders use sticky capture spiral silk to retain prey in webs. Capture spiral silk is composed of an axial fibre of flagelliform silk covered with glue droplets that are arranged in a beads-on-a-string morphology that allows multiple droplets to simultaneously extend and resist pull off. Previous studies showed that the adhesion of capture silk is responsive to environmental humidity, increasing up to an optimum humidity that varied among different spider species. The maximum adhesion was hypothesized to occur when the viscoelasticity of the glue optimized contributions from glue spreading and bulk cohesion...
May 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28467651/n-bodipys-come-into-play-smart-dyes-for-photonic-materials
#3
César Ray, Laura Díaz-Casado, Edurne Avellanal, Jorge Bañuelos, Luis Cerdán, Inmaculada García-Moreno, Florencio Moreno, Beatriz L Maroto, Iñigo López-Arbeloa, Santiago de la Moya Cerero
N-BODIPYs (diaminoboron dipyrromethenes) are unveiled as a new family of BODIPY dyes with huge technological potential. Their synthetic access is accomplished from a judicious design focused on stabilizing the involved diaminoboron chelate. Once stabilized, achieved N-BODIPYs retain the effective photophysical behavior exhibited by other boron-substituted BODIPYs, such as the O-BODIPYs. However, key bonding features of nitrogen, when compared with oxygen (enhanced bond valence and different bond directionality) open up new possibilities for functionalizing BODIPYs, allowing the increase of the number of pendant moieties (from two in O-BODIPYs, up to four in N-BODIPYs) near the chromophore and, therefore, a smarter photophysics modulation...
May 3, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28419302/the-posthuman-as-hollow-idol-a-nietzschean-critique-of-human-enhancement
#4
Ciano Aydin
In this paper, the author aims to show that transhumanists are confused about their own conception of the posthuman: transhumanists anticipate radical transformation of the human through technology and at the same time assume that the criteria to determine what is "normal" and what is "enhanced" are univocal, both in our present time and in the future. Inspired by Nietzsche's notion of the Overhuman, the author argues that the slightest "historical and phenomenological sense" discloses copious variations of criteria, both diachronic and synchronic, for what can be considered "normal" and "enhanced...
June 1, 2017: Journal of Medicine and Philosophy
https://www.readbyqxmd.com/read/28409090/the-smarter-pilot-study-testing-feasibility-of-real-time-feedback-for-dietary-self-monitoring
#5
Lora E Burke, Yaguang Zheng, Qianheng Ma, Juliet Mancino, India Loar, Edvin Music, Mindi Styn, Linda Ewing, Brian French, Dan Sieworek, Asim Smailagic, Susan M Sereika
Self-monitoring (SM) of food intake is central to weight loss treatment. Technology makes it possible to reinforce this behavior change strategy by providing real-time feedback (FB) tailored to the diary entry. To test the feasibility of providing 1-4 daily FB messages tailored to dietary recordings via a smartphone, we conducted a 12-week pilot randomized clinical trial in Pittsburgh, PA in US in 2015. We compared 3 groups: SM using the Lose It! smartphone app (Group 1); SM + FB (Group 2); and SM + FB + attending three in-person group sessions (Group 3)...
June 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28381476/moderate-to-vigorous-physical-activity-but-not-sedentary-time-predicts-changes-in-cardiometabolic-risk-factors-in-10-y-old-children-the-active-smarter-kids-study
#6
Turid Skrede, Mette Stavnsbo, Eivind Aadland, Katrine N Aadland, Sigmund A Anderssen, Geir K Resaland, Ulf Ekelund
Background: Cross-sectional data have suggested an inverse relation between physical activity and cardiometabolic risk factors that is independent of sedentary time. However, little is known about which subcomponent of physical activity may predict cardiometabolic risk factors in youths.Objective: We examined the independent prospective associations between objectively measured sedentary time and subcomponents of physical activity with individual and clustered cardiometabolic risk factors in healthy children aged 10 y...
April 5, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28319656/the-role-of-pulses-in-sustainable-and-healthy-food-systems
#7
REVIEW
John McDermott, Amanda J Wyatt
Improving nutrition is a development priority, particularly in low- and middle-income countries (LMICs) in Africa and South Asia, in which there is a persistent burden of undernutrition and increasing obesity. Healthy food systems can play a necessary role, aligned with other multisectoral actions, in addressing this challenge. Contributing to improved nutrition and health outcomes through food-based solutions is complex. In considering the role that pulses can play in addressing this challenge, there are useful conceptual frameworks and emerging lessons...
March 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28306149/medicare-access-and-chip-reauthorization-act-what-do-geriatrics-healthcare-professionals-need-to-know-about-the-quality-payment-program
#8
Kathleen T Unroe, Peter A Hollmann, Alanna C Goldstein, Michael L Malone
Commencing in 2017, the Medicare Access and CHIP Reauthorization Act (MACRA) of 2015 will change how Medicare pays health professionals. By enacting MACRA, Congress brought an end to the (un)sustainable growth rate formula while also setting forth a vision for how to transform the U.S. healthcare system so that clinicians deliver higher-quality care with smarter spending by the Centers for Medicare and Medicaid Services (CMS). In October 2016, CMS released the first of what stakeholders anticipate will be a number of (annual) rules related to implementation of MACRA...
April 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28281865/a-randomized-controlled-trial-to-improve-the-success-of-women-assistant-professors
#9
Jeane Ann Grisso, Mary Dupuis Sammel, Arthur H Rubenstein, Rebecca M Speck, Emily F Conant, Patricia Scott, Lucy Wolf Tuton, Alyssa Friede Westring, Stewart Friedman, Stephanie B Abbuhl
BACKGROUND: Given the persistent disparity in the advancement of women compared with men faculty in academic medicine, it is critical to develop effective interventions to enhance women's careers. We carried out a cluster-randomized, multifaceted intervention to improve the success of women assistant professors at a research-intensive medical school. MATERIALS AND METHODS: Twenty-seven departments/divisions were randomly assigned to intervention or control groups...
February 28, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28268935/deep-neural-network-architectures-for-forecasting-analgesic-response
#10
Paul Nickerson, Patrick Tighe, Benjamin Shickel, Parisa Rashidi
Response to prescribed analgesic drugs varies between individuals, and choosing the right drug/dose often involves a lengthy, iterative process of trial and error. Furthermore, a significant portion of patients experience adverse events such as post-operative urinary retention (POUR) during inpatient management of acute postoperative pain. To better forecast analgesic responses, we compared conventional machine learning methods with modern neural network architectures to gauge their effectiveness at forecasting temporal patterns of postoperative pain and analgesic use, as well as predicting the risk of POUR...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28266250/mammography-developing-a-smarter-and-safer-alternative
#11
Ruud Jg van Sloun, Libertario Demi, Hessel Wijkstra, Massimo Mischi
No abstract text is available yet for this article.
April 2017: Future Oncology
https://www.readbyqxmd.com/read/28254064/smart-biomaterials-smarter-medicine
#12
EDITORIAL
(no author information available yet)
No abstract text is available yet for this article.
February 2017: EBioMedicine
https://www.readbyqxmd.com/read/28227141/deep-neural-network-architectures-for-forecasting-analgesic-response
#13
Paul Nickerson, Patrick Tighe, Benjamin Shickel, Parisa Rashidi, Paul Nickerson, Patrick Tighe, Benjamin Shickel, Parisa Rashidi, Parisa Rashidi, Paul Nickerson, Patrick Tighe, Benjamin Shickel
Response to prescribed analgesic drugs varies between individuals, and choosing the right drug/dose often involves a lengthy, iterative process of trial and error. Furthermore, a significant portion of patients experience adverse events such as post-operative urinary retention (POUR) during inpatient management of acute postoperative pain. To better forecast analgesic responses, we compared conventional machine learning methods with modern neural network architectures to gauge their effectiveness at forecasting temporal patterns of postoperative pain and analgesic use, as well as predicting the risk of POUR...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28221220/impact-of-the-united-states-preventive-services-task-force-d-recommendation-on-prostate-cancer-screening-and-staging
#14
Renu S Eapen, Annika Herlemann, Samuel L Washington, Matthew R Cooperberg
PURPOSE OF REVIEW: In 2012, the United States Preventive Services Task Force (USPSTF) issued a grade 'D' recommendation against the use of routine prostate-specific antigen (PSA)-based screening for any men. This recommendation reflects critical misinterpretations of the available evidence base regarding benefits and harms of PSA screening and has influenced the nationwide landscape of prostate cancer screening, diagnosis, and treatment. RECENT FINDINGS: Following the USPSTF recommendation, a substantial decline in PSA screening was noted for all age groups...
May 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/28214248/fruit-promoting-smarter-lunchrooms-interventions-results-from-a-cluster-rct
#15
Katherine N Greene, Gnel Gabrielyan, David R Just, Brian Wansink
INTRODUCTION: The Smarter Lunchrooms Movement was developed to provide schools with simple, low-cost solutions to encourage students to make healthier food choices at school. The objective of this study was to evaluate the impact of fruit-promoting Smarter Lunchroom interventions on middle school students' selection and consumption of fruits. DESIGN: A 9-week cluster RCT was conducted using a pre-test/post-test control group design in upstate New York in February-April 2014...
February 13, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28213316/opportunities-for-epilepsy-outcomes-of-the-milken-institute-state-of-the-science-retreat
#16
Sonya B Dumanis, Ekemini A U Riley, LaTese Briggs, YooRi Kim, Erik Lontok, Danielle Salka, Melissa Stevens
The Milken Institute Center for Strategic Philanthropy has launched a Giving Smarter Program in Epilepsy to inform philanthropists on the state of the science for the epilepsy field, key challenges, and solutions to address them. As part of the program, the Milken Institute Center for Strategic Philanthropy hosted a retreat to identify strategic investments that would accelerate epilepsy research to ultimately improve care. The top three prioritized opportunities from the retreat were to 1) invest in data standards and analytical tool development, 2) support young investigators, and 3) promote cross-sector collaborations especially between basic scientists, preclinical researchers, clinicians, and patients...
February 14, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28174517/a-practical-guide-to-approaching-biased-agonism-at-g-protein-coupled-receptors
#17
Jaimee Gundry, Rachel Glenn, Priya Alagesan, Sudarshan Rajagopal
Biased agonism, the ability of a receptor to differentially activate downstream signaling pathways depending on binding of a "biased" agonist compared to a "balanced" agonist, is a well-established paradigm for G protein-coupled receptor (GPCR) signaling. Biased agonists have the promise to act as smarter drugs by specifically targeting pathogenic or therapeutic signaling pathways while avoiding others that could lead to side effects. A number of biased agonists targeting a wide array of GPCRs have been described, primarily based on their signaling in pharmacological assays...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28137701/a-smarter-pathway-for-delivering-cue-exposure-therapy-the-design-and-development-of-a-smartphone-app-targeting-alcohol-use-disorder
#18
Angelina Isabella Mellentin, Elsebeth Stenager, Bent Nielsen, Anette Søgaard Nielsen, Fei Yu
BACKGROUND: Although the number of alcohol-related treatments in app stores is proliferating, none of them are based on a psychological framework and supported by empirical evidence. Cue exposure treatment (CET) with urge-specific coping skills (USCS) is often used in Danish treatment settings. It is an evidence-based psychological approach that focuses on promoting "confrontation with alcohol cues" as a means of reducing urges and the likelihood of relapse. OBJECTIVE: The objective of this study was to describe the design and development of a CET-based smartphone app; an innovative delivery pathway for treating alcohol use disorder (AUD)...
January 30, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28129576/evaluating-the-effectiveness-of-active-vehicle-safety-systems
#19
Eunbi Jeong, Cheol Oh
Advanced vehicle safety systems have been widely introduced in transportation systems and are expected to enhance traffic safety. However, these technologies mainly focus on assisting individual vehicles that are equipped with them, and less effort has been made to identify the effect of vehicular technologies on the traffic stream. This study proposed a methodology to assess the effectiveness of active vehicle safety systems (AVSSs), which represent a promising technology to prevent traffic crashes and mitigate injury severity...
March 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28125970/the-use-of-the-mhealth-program-smarter-pregnancy-in-preconception-care-rationale-study-design-and-data-collection-of-a-randomized-controlled-trial
#20
Matthijs R van Dijk, Elsje C Oostingh, Maria P H Koster, Sten P Willemsen, Joop S E Laven, Régine P M Steegers-Theunissen
BACKGROUND: Unhealthy nutrition and lifestyle contribute to the worldwide rising prevalence of non-communicable diseases. This also accounts for the reproductive population, in which unhealthy behavior affects fertility and pregnancy outcome. Maternal smoking, alcohol consumption and inadequate folic acid supplement use are strongly associated with fetal complications as small for gestational age, premature birth and congenital malformations. In the Netherlands 83% of the perinatal mortality rate is due to these complications and is relatively high compared to other European countries...
January 26, 2017: BMC Pregnancy and Childbirth
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