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Magnetic resonance imaging

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https://www.readbyqxmd.com/read/28214332/comparison-of-several-white-matter-tracts-in-feline-and-canine-brain-by-using-magnetic-resonance-diffusion-tensor-imaging
#1
Olivier Jacqmot, Bert Van Thielen, Alex Michotte, Inneke Willekens, Filip Verhelle, Peter Goossens, Filip De Ridder, Jan Pieter Clarys, Anne Vanbinst, Cindy Peleman, Johan de Mey
Recently, we published a first anatomical Diffusion Tensor Imaging (DTI) atlas regarding white matter tracts in the canine brain. The purpose of this study was to show the significance of DTI in the revelation of the white matter fibres in the feline brain (i.e. to obtain an anatomical DTI atlas of images) and to descriptively compare these to previously obtained white matter fibre images of the canine brain. DTI MR Images of 4 cats euthanised for reasons other than neurological disorders were obtained with a 3 T system...
February 18, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28214172/does-successful-rotator-cuff-repair-improve-muscle-atrophy-and-fatty-infiltration-of-the-rotator-cuff-a-retrospective-magnetic-resonance-imaging-study-performed-shortly-after-surgery-as-a-reference
#2
Noritaka Hamano, Atsushi Yamamoto, Hitoshi Shitara, Tsuyoshi Ichinose, Daisuke Shimoyama, Tsuyoshi Sasaki, Tsutomu Kobayashi, Yohei Kakuta, Toshihisa Osawa, Kenji Takagishi
BACKGROUND: Muscle atrophy and fatty infiltration in the rotator cuff muscles are often observed in patients with chronic rotator cuff tears. The recovery from these conditions has not been clarified. METHODS: Ninety-four patients were included in this study. The improvement in muscle atrophy and fatty infiltration in successfully repaired rotator cuff tears was evaluated by magnetic resonance imaging at 1 year and 2 years after surgery and was compared with muscle atrophy and fatty infiltration observed on magnetic resonance imaging at 2 weeks after surgery to discount any changes due to the medial retraction of the torn tendon...
February 15, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28214165/agenesis-of-the-corpus-callosum-and-aicardi-syndrome-a%C3%A2-neuroimaging-and-clinical-comparison
#3
T Govil-Dalela, A Kumar, R Agarwal, H T Chugani
BACKGROUND: Agenesis of the corpus callosum can occur in individuals with epilepsy, either in isolation or as part of various neurological conditions, such as Aicardi syndrome. In this study, we evaluated the clinical and neuroradiological differences between children with nonsyndromic agenesis of the corpus callosum and those with Aicardi syndrome. METHODS: We evaluated 31 children with epilepsy and agenesis of the corpus callosum (11 males, 20 females), 14 of whom had Aicardi syndrome (all females)...
January 4, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28214153/arrhythmogenic-right-ventricular-dysplasia-atypical-clinical-presentation
#4
José Marçalo, Luiz Menezes Falcão
A 67-year-old man was admitted to our hospital after episodes of syncope preceded by malaise and diffuse neck and chest discomfort. No family history of cardiac disease was reported. Laboratory workup was within normal limits, including D-dimers, serum troponin I and arterial blood gases. The electrocardiogram showed sinus rhythm with T-wave inversion in leads V1 to V3. Computed tomography angiography to investigate pulmonary embolism showed no abnormal findings. Transthoracic echocardiography (TTE) displayed massive enlargement of the right ventricle with intact interatrial septum and no pulmonary hypertension...
February 14, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/28214127/functionalized-superparamagnetic-iron-oxide-nanoparticles-provide-highly-efficient-iron-labeling-in-macrophages-for-magnetic-resonance-based-detection-in-vivo
#5
Jack Sharkey, Philip J Starkey Lewis, Michael Barrow, Salamah M Alwahsh, June Noble, Eilidh Livingstone, Ross J Lennen, Maurits A Jansen, Jaime Garcia Carrion, Neill Liptrott, Shareen Forbes, Dave J Adams, Amy E Chadwick, Stuart J Forbes, Patricia Murray, Matthew J Rosseinsky, Christopher E Goldring, B Kevin Park
BACKGROUND AIMS: Tracking cells during regenerative cytotherapy is crucial for monitoring their safety and efficacy. Macrophages are an emerging cell-based regenerative therapy for liver disease and can be readily labeled for medical imaging. A reliable, clinically applicable cell-tracking agent would be a powerful tool to study cell biodistribution. METHODS: Using a recently described chemical design, we set out to functionalize, optimize and characterize a new set of superparamagnetic iron oxide nanoparticles (SPIONs) to efficiently label macrophages for magnetic resonance imaging-based cell tracking in vivo...
February 15, 2017: Cytotherapy
https://www.readbyqxmd.com/read/28213908/a-randomized-controlled-trial-of-lacosamide-versus-sodium-valproate-in-status-epilepticus
#6
Usha K Misra, Deepanshu Dubey, Jayantee Kalita
OBJECTIVE: To compare the efficacy and safety of lacosamide (LCM) and sodium valproate (SVA) in lorazepam (LOR)-resistant status epilepticus (SE). METHODS: Patients with LOR-resistant SE were randomized to intravenous LCM 400 mg at a rate of 60 mg/kg/min or SVA 30 mg/kg at a rate of 100 mg/min. The SE severity score (STESS), duration of SE and its etiology, and magnetic resonance imaging (MRI) findings were noted. Primary outcome was seizure cessation for 1 h, and secondary outcomes were 24 h seizure remission, in hospital death and severe adverse events (SAEs)...
February 18, 2017: Epilepsia
https://www.readbyqxmd.com/read/28213852/-imaging-of-the-lumbosacral-plexus-diagnostics-and-treatment-planning-with-high-resolution-procedures
#7
S Jengojan, C Schellen, G Bodner, G Kasprian
BACKGROUND: Technical advances in magnetic resonance (MR) and ultrasound-based neurography nowadays facilitate the radiological assessment of the lumbosacral plexus. OBJECTIVE: Anatomy and imaging of the lumbosacral plexus and diagnostics of the most common pathologies. MATERIAL AND METHODS: Description of the clinically feasible combination of magnetic resonance imaging (MRI) and ultrasound diagnostics, case-based illustration of imaging techniques and individual advantages of MRI and ultrasound-based diagnostics for various pathologies of the lumbosacral plexus and its peripheral nerves...
February 17, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28213833/molecular-imaging-in-synthetic-biology-and-synthetic-biology-in-molecular-imaging
#8
REVIEW
Assaf A Gilad, Mikhail G Shapiro
Biomedical synthetic biology is an emerging field in which cells are engineered at the genetic level to carry out novel functions with relevance to biomedical and industrial applications. This approach promises new treatments, imaging tools, and diagnostics for diseases ranging from gastrointestinal inflammatory syndromes to cancer, diabetes, and neurodegeneration. As these cellular technologies undergo pre-clinical and clinical development, it is becoming essential to monitor their location and function in vivo, necessitating appropriate molecular imaging strategies, and therefore, we have created an interest group within the World Molecular Imaging Society focusing on synthetic biology and reporter gene technologies...
February 17, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28213703/proximal-tibial-bony-and-meniscal-slopes-are-higher-in-acl-injured-subjects-than-controls-a-comparative-mri-study
#9
Ashraf Elmansori, Timothy Lording, Raphaël Dumas, Khalifa Elmajri, Philippe Neyret, Sébastien Lustig
PURPOSE: Increased tibial slope is reported as a risk factor of non-contact anterior cruciate ligament (ACL) injury, but the effect of the soft tissues on slope remains unclear. The primary aims of this study were to compare the tibial bony and soft tissue slopes between patients with and without ACL injury, and to investigate the relationship between the meniscal slopes (MS) and the tibial bony slope. Our hypothesis was that the menisci would correct the inclination of the bony tibial slope towards the horizontal...
February 17, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28213448/detection-and-monitoring-of-acute-myocarditis-applying-quantitative-cardiovascular-magnetic-resonance
#10
Florian von Knobelsdorff-Brenkenhoff, Johannes Schüler, Serkan Dogangüzel, Matthias A Dieringer, Andre Rudolph, Andreas Greiser, Peter Kellman, Jeanette Schulz-Menger
BACKGROUND: Cardiovascular magnetic resonance based on the Lake Louise Criteria is used to make the diagnosis of acute myocarditis. Novel quantitative parametric mapping techniques promise to overcome some of its limitations. We aimed to evaluate quantitative cardiovascular magnetic resonance to detect and monitor acute myocarditis. METHODS AND RESULTS: Eighteen patients with clinical diagnosis of acute myocarditis (25 years [23-38 years]; 78% males) were prospectively enrolled and repeatedly underwent cardiovascular magnetic resonance at 1...
February 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28213445/ultra-high-field-fmri-reveals-a-role-for-the-subiculum-in-scene-perceptual-discrimination
#11
Carl J Hodgetts, Natalie L Voets, Adam G Thomas, Stuart Clare, Andrew D Lawrence, Kim S Graham
Recent 'representational' accounts suggest a key role for the hippocampus in complex scene perception. Due to limitations in scanner field strength, however, the functional neuroanatomy of hippocampal-dependent scene perception is unknown. Here, we applied 7-Tesla high-resolution functional magnetic resonance imaging (fMRI) alongside a perceptual oddity task, modified from non-human primate studies. This task requires subjects to discriminate highly similar scenes, faces or objects from multiple viewpoints, and has revealed selective impairments during scene discrimination following hippocampal lesions...
February 17, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28213439/tau-and-%C3%AE-amyloid-are-associated-with-medial-temporal-lobe-structure-function-and-memory-encoding-in-normal-aging
#12
Shawn M Marks, Samuel N Lockhart, Suzanne L Baker, William J Jagust
Normal aging is associated with decline in episodic memory, and also with aggregation of the β-amyloid (Aβ) and tau proteins and atrophy of medial temporal lobe structures crucial to memory formation. While some evidence suggests that Aβ is associated with aberrant neural activity, the relationships between these two aggregated proteins, neural function, and brain structure are poorly understood. Using in vivo human Aβ and tau imaging, we demonstrate that increased Aβ and tau are both associated with aberrant functional magnetic resonance imaging activity in the medial temporal lobes during memory encoding in cognitively normal older adults...
February 17, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28213198/a-rare-presentation-of-an-enterogenous-cyst-as-an-intra-axial-pontine-lesion
#13
Tengfei Li, Xia Wu, Yuekang Zhang
A 56-year-old man was admitted to our hospital with intermittent right facial numbness for one year and walking instability for six months. Magnetic resonance imaging revealed an ovoid and well-demarcated intra-axial pontine lesion. Cyst fenestration and biopsy were carried out and the diagnosis of enterogenous cyst was made by MRI and pathologic findings. Preoperative symptoms resolved completely three months after surgery and no evidence of recurrence was found during 3 years of follow-up. Although total resection of enterogenous cysts is recommended, cyst fenestration may be useful if the cyst is adherent to vital neurovascular structures...
February 14, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28213118/the-global-signal-in-fmri-nuisance-or-information
#14
Thomas T Liu, Alican Nalci, Maryam Falahpour
The global signal is widely used as a regressor or normalization factor for removing the effects of global variations in the analysis of functional magnetic resonance imaging (fMRI) studies. However, there is considerable controversy over its use because of the potential bias that can be introduced when it is applied to the analysis of both task-related and resting-state fMRI studies. In this paper we take a closer look at the global signal, examining in detail the various sources that can contribute to the signal...
February 14, 2017: NeuroImage
https://www.readbyqxmd.com/read/28213112/laminar-imaging-of-positive-and-negative-bold-in-human-visual-cortex-at-7t
#15
Alessio Fracasso, Peter R Luijten, Serge O Dumoulin, Natalia Petridou
Deciphering the direction of information flow is critical to understand the brain. Data from non-human primate histology shows that connections between lower to higher areas (e.g. retina→V1), and between higher to lower areas (e.g. V1←V2) can be dissociated based upon the distribution of afferent synapses at the laminar level. Ultra-high field scanners opened up the possibility to image brain structure and function at an unprecedented level of detail. Taking advantage of the increased spatial resolution available, it could theoretically be possible to disentangle activity from different cortical depths from human cerebral cortex, separately studying different compartments across depth...
February 14, 2017: NeuroImage
https://www.readbyqxmd.com/read/28213087/a-rare-case-of-bruns-syndrome-with-bilateral-superior-oblique-palsy-and-dorsal-midbrain-syndrome
#16
Rebika Dhiman, Medha Sharma, Anin Sethi, Sanjay Sharma, Atin Kumar, Rohit Saxena
We report a case of an 11-year-old boy referred for evaluation of esotropia associated with a 4-year history of intermittent headaches and vomiting triggered by sudden movements, such as sneezing and coughing. Magnetic resonance imaging (MRI) performed 3 years previously was reported to be normal. A thorough clinical examination revealed the clinical features of Dorsal midbrain syndrome with Bruns syndrome and bilateral superior oblique palsy. Advanced MRI sequences revealed a freely mobile intraventricular cysticercus causing obstructive panhydrocephalus...
February 14, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28212618/clinical-features-and-outcome-in-patients-with-osseomuscular-type-of-wilson-s-disease
#17
Hao Yu, Juan-Juan Xie, Yu-Chao Chen, Qin-Yun Dong, Yi Dong, Wang Ni, Zhi-Ying Wu
BACKGROUND: Wilson's disease with osseomuscular type is a rare condition, which often lacks typical hepatic and neurological symptoms and causes misdiagnoses easily. During the past 10 years, eight Chinese patients of osseomuscular type of Wilson's disease were identified in our clinic. METHODS: Clinical information was gathered from medical records and follow-ups. The genetic testing was performed in each patient. Serum ceruloplasmin, Kayser-Fleischer rings, liver function, brain magnetic resonance imaging and abdominal ultrasonography were also evaluated...
February 17, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28212385/the-effect-of-tumour-size-on-drug-transport-and-uptake-in-3-d-tumour-models-reconstructed-from-magnetic-resonance-images
#18
Wenbo Zhan, Wladyslaw Gedroyc, Xiao Yun Xu
Drug transport and its uptake by tumour cells are strongly dependent on tumour properties, which vary in different types of solid tumours. By simulating the key physical and biochemical processes, a numerical study has been carried out to investigate the transport of anti-cancer drugs in 3-D tumour models of different sizes. The therapeutic efficacy for each tumour is evaluated by using a pharmacodynamics model based on the predicted intracellular drug concentration. Simulation results demonstrate that interstitial fluid pressure and interstitial fluid loss vary non-linearly with tumour size...
2017: PloS One
https://www.readbyqxmd.com/read/28212053/transthoracic-echocardiography-pitfalls-and-limitations-as-delineated-at-cardiac-ct-and-mr-imaging
#19
Sachin B Malik, Natalie Chen, Rex A Parker, Joe Y Hsu
Transthoracic echocardiography ( TTE transthoracic echocardiography ) is a critical tool in the field of clinical cardiology. It often serves as one of the first-line imaging modalities in the evaluation of cardiac disease owing to its low cost, portability, widespread availability, lack of ionizing radiation, and ability to evaluate both anatomy and function of the heart. Consequently, a large majority of patients undergoing a cardiac computed tomography (CT) or magnetic resonance (MR) imaging examination will have a TTE transthoracic echocardiography available for review...
February 17, 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28212052/proton-density-fat-fraction-measurements-at-1-5-and-3-t-hepatic-mr-imaging-same-day-agreement-among-readers-and-across-two-imager-manufacturers
#20
Suraj D Serai, Jonathan R Dillman, Andrew T Trout
Purpose To determine the agreement of proton density fat fraction (PDFF) measurements obtained with hepatic magnetic resonance (MR) imaging among readers, imager manufacturers, and field strengths. Materials and Methods This HIPAA-compliant study was approved by the institutional review board. After providing informed consent, 24 adult volunteers underwent imaging with one 1.5-T MR unit (Ingenia; Philips Healthcare, Best, the Netherlands) and two different 3.0-T units (750 W [GE Healthcare, Waukesha, Wis] and Ingenia) on the same day to estimate hepatic PDFF...
February 24, 2017: Radiology
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